SE510666C2 - Nya Kristallmodifikationer - Google Patents

Nya Kristallmodifikationer

Info

Publication number
SE510666C2
SE510666C2 SE9604793A SE9604793A SE510666C2 SE 510666 C2 SE510666 C2 SE 510666C2 SE 9604793 A SE9604793 A SE 9604793A SE 9604793 A SE9604793 A SE 9604793A SE 510666 C2 SE510666 C2 SE 510666C2
Authority
SE
Sweden
Prior art keywords
omeprazole
neutral
solution
solvent
water
Prior art date
Application number
SE9604793A
Other languages
English (en)
Swedish (sv)
Other versions
SE9604793D0 (sv
SE9604793L (sv
Inventor
Martin Bohlin
Karol Horvath
Sverker Von Unge
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20405146&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SE510666(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astra Ab filed Critical Astra Ab
Priority to SE9604793A priority Critical patent/SE510666C2/sv
Publication of SE9604793D0 publication Critical patent/SE9604793D0/xx
Priority to TW086118449A priority patent/TW538039B/zh
Priority to ZA9711046A priority patent/ZA9711046B/xx
Priority to RU99116303/04A priority patent/RU2184734C2/ru
Priority to DE69720774T priority patent/DE69720774T2/de
Priority to IL13045097A priority patent/IL130450A0/xx
Priority to SI9730528T priority patent/SI0946547T1/xx
Priority to EEP199900259A priority patent/EE03923B1/xx
Priority to US09/000,154 priority patent/US6162816A/en
Priority to NZ336024A priority patent/NZ336024A/en
Priority to ES97951367T priority patent/ES2194231T3/es
Priority to HK00101986.4A priority patent/HK1022909B/en
Priority to TR1999/01410T priority patent/TR199901410T2/xx
Priority to CN97180849A priority patent/CN1109684C/zh
Priority to SK765-99A priority patent/SK285151B6/sk
Priority to CA002274076A priority patent/CA2274076C/en
Priority to AU55026/98A priority patent/AU730129B2/en
Priority to ARP970105920A priority patent/AR010361A1/es
Priority to KR1019997005574A priority patent/KR20000069595A/ko
Priority to UA99073869A priority patent/UA55436C2/uk
Priority to CZ19992202A priority patent/CZ294784B6/cs
Priority to BR9714059-7A priority patent/BR9714059A/pt
Priority to PT97951367T priority patent/PT946547E/pt
Priority to HU0001547A priority patent/HU227589B1/hu
Priority to PL97334297A priority patent/PL190377B1/pl
Priority to IDW990483A priority patent/ID21850A/id
Priority to YUP-281/99A priority patent/RS49685B/sr
Priority to JP52868598A priority patent/JP4402174B2/ja
Priority to EP97951367A priority patent/EP0946547B1/en
Priority to PCT/SE1997/002125 priority patent/WO1998028294A1/en
Priority to DK97951367T priority patent/DK0946547T3/da
Priority to AT97951367T priority patent/ATE236898T1/de
Priority to MYPI97006176A priority patent/MY117032A/en
Priority to EG136097A priority patent/EG24414A/xx
Priority to SA97180739A priority patent/SA97180739B1/ar
Publication of SE9604793L publication Critical patent/SE9604793L/xx
Priority to IS5070A priority patent/IS1981B/is
Publication of SE510666C2 publication Critical patent/SE510666C2/sv
Priority to NO19993068A priority patent/NO317191B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SE9604793A 1996-12-20 1996-12-20 Nya Kristallmodifikationer SE510666C2 (sv)

Priority Applications (37)

Application Number Priority Date Filing Date Title
SE9604793A SE510666C2 (sv) 1996-12-20 1996-12-20 Nya Kristallmodifikationer
TW086118449A TW538039B (en) 1996-12-20 1997-12-08 Neutral S-omeprazole in a form or b form, process for preparing the same, and pharmaceutical composition comprising the same
ZA9711046A ZA9711046B (en) 1996-12-20 1997-12-09 A novel compound form.
DK97951367T DK0946547T3 (da) 1996-12-20 1997-12-16 Hidtil ukendt forbindelsesform
AT97951367T ATE236898T1 (de) 1996-12-20 1997-12-16 S-omeprazol in festform
ARP970105920A AR010361A1 (es) 1996-12-20 1997-12-16 "S-OMEPRAZOL [ENANTIoMERO S DE 5-METOXI-2-[[(4--METOXI-3,5-DIMETIL-2-PIRIDINIL)-METIL]SULFINIL]-1H-BENCIMIDAZOL], EN UNA FORMA NEUTRA NO SALINA, PROCESO PARA SU PREPARACION, COMPOSICION FARMACEUTICA, Y SU USO PARA LA MANUFACTURA DE MEDICAMENTOS"
CZ19992202A CZ294784B6 (cs) 1996-12-20 1997-12-16 Nová forma S-omeprazolu
IL13045097A IL130450A0 (en) 1996-12-20 1997-12-16 A novel compound form
SI9730528T SI0946547T1 (en) 1996-12-20 1997-12-16 A novel compound form
EEP199900259A EE03923B1 (et) 1996-12-20 1997-12-16 S-omeprasool neutraalsel kujul, selle valmistamise protsess ja seda sisaldavad ravimsegud
US09/000,154 US6162816A (en) 1996-12-20 1997-12-16 Crystalline form of the S-enantiomer of omeprazole
NZ336024A NZ336024A (en) 1996-12-20 1997-12-16 Neutral crystalline S-omeprazole
ES97951367T ES2194231T3 (es) 1996-12-20 1997-12-16 Una nueva forma de compuesto.
HK00101986.4A HK1022909B (en) 1996-12-20 1997-12-16 A novel compound form
TR1999/01410T TR199901410T2 (xx) 1996-12-20 1997-12-16 Yeni bir bile�im bi�imi.
CN97180849A CN1109684C (zh) 1996-12-20 1997-12-16 新的化合物形态
SK765-99A SK285151B6 (sk) 1996-12-20 1997-12-16 Neutrálna forma S-enantioméru omeprazolu, spôsob jeho prípravy, farmaceutická kompozícia s jeho obsahom a jeho použitie
CA002274076A CA2274076C (en) 1996-12-20 1997-12-16 Crystalline form of s-omeprazole
AU55026/98A AU730129B2 (en) 1996-12-20 1997-12-16 A novel compound form
RU99116303/04A RU2184734C2 (ru) 1996-12-20 1997-12-16 S-омепразол в нейтральной форме, способы его получения, фармацевтическая композиция, содержащая s-омепразол в нейтральной форме, и способ лечения связанного с желудочной кислотой состояния
KR1019997005574A KR20000069595A (ko) 1996-12-20 1997-12-16 신규한 형태의 화합물
UA99073869A UA55436C2 (uk) 1996-12-20 1997-12-16 Нова форма s-омепразолу, спосіб його одержання, фармацевтична композиція та використання у виробництві лікувального засобу
DE69720774T DE69720774T2 (de) 1996-12-20 1997-12-16 S-omeprazol in festform
BR9714059-7A BR9714059A (pt) 1996-12-20 1997-12-16 S-omeprazol em uma forma neutra, processo para preparar o mesmo, uso deste, composição farmacêutica, e, processo para tratar uma condição relacionada com ácido gástrico.
PT97951367T PT946547E (pt) 1996-12-20 1997-12-16 Nova forma de composto
HU0001547A HU227589B1 (en) 1996-12-20 1997-12-16 Crystal form of (s)-omeprazole
PL97334297A PL190377B1 (pl) 1996-12-20 1997-12-16 S-Omeprazol w postaci obojętnej, sposób wytwarzania S-omeprazolu, środek farmaceutyczny i zastosowanie S-omeprazolu
IDW990483A ID21850A (id) 1996-12-20 1997-12-16 Formula senyawa baru
YUP-281/99A RS49685B (sr) 1996-12-20 1997-12-16 Novi oblik jedinjenja
JP52868598A JP4402174B2 (ja) 1996-12-20 1997-12-16 新規な化合物形態
EP97951367A EP0946547B1 (en) 1996-12-20 1997-12-16 A novel compound form
PCT/SE1997/002125 WO1998028294A1 (en) 1996-12-20 1997-12-16 A novel compound form
MYPI97006176A MY117032A (en) 1996-12-20 1997-12-19 A novel compound form.
EG136097A EG24414A (en) 1996-12-20 1997-12-20 A novel compound form
SA97180739A SA97180739B1 (ar) 1996-12-20 1997-12-27 الشكل البللوري للمتشاكل S - enantiomer للأومبرازول omeprazole
IS5070A IS1981B (is) 1996-12-20 1999-06-07 Nýtt form S-handhverfu ómeprasóls og lyfjablöndursem innihalda það
NO19993068A NO317191B1 (no) 1996-12-20 1999-06-21 S-omeprazol i noytral form, fremgangsmate for fremstilling derav, farmasoytisk preparat inneholdende en slik form, og anvendelse derav

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9604793A SE510666C2 (sv) 1996-12-20 1996-12-20 Nya Kristallmodifikationer

Publications (3)

Publication Number Publication Date
SE9604793D0 SE9604793D0 (sv) 1996-12-20
SE9604793L SE9604793L (sv) 1998-06-21
SE510666C2 true SE510666C2 (sv) 1999-06-14

Family

ID=20405146

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9604793A SE510666C2 (sv) 1996-12-20 1996-12-20 Nya Kristallmodifikationer

Country Status (36)

Country Link
US (1) US6162816A (enExample)
EP (1) EP0946547B1 (enExample)
JP (1) JP4402174B2 (enExample)
KR (1) KR20000069595A (enExample)
CN (1) CN1109684C (enExample)
AR (1) AR010361A1 (enExample)
AT (1) ATE236898T1 (enExample)
AU (1) AU730129B2 (enExample)
BR (1) BR9714059A (enExample)
CA (1) CA2274076C (enExample)
CZ (1) CZ294784B6 (enExample)
DE (1) DE69720774T2 (enExample)
DK (1) DK0946547T3 (enExample)
EE (1) EE03923B1 (enExample)
EG (1) EG24414A (enExample)
ES (1) ES2194231T3 (enExample)
HU (1) HU227589B1 (enExample)
ID (1) ID21850A (enExample)
IL (1) IL130450A0 (enExample)
IS (1) IS1981B (enExample)
MY (1) MY117032A (enExample)
NO (1) NO317191B1 (enExample)
NZ (1) NZ336024A (enExample)
PL (1) PL190377B1 (enExample)
PT (1) PT946547E (enExample)
RS (1) RS49685B (enExample)
RU (1) RU2184734C2 (enExample)
SA (1) SA97180739B1 (enExample)
SE (1) SE510666C2 (enExample)
SI (1) SI0946547T1 (enExample)
SK (1) SK285151B6 (enExample)
TR (1) TR199901410T2 (enExample)
TW (1) TW538039B (enExample)
UA (1) UA55436C2 (enExample)
WO (1) WO1998028294A1 (enExample)
ZA (1) ZA9711046B (enExample)

Families Citing this family (60)

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US6699885B2 (en) 1996-01-04 2004-03-02 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and methods of using same
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
US6645988B2 (en) 1996-01-04 2003-11-11 Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
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UA72748C2 (en) * 1998-11-10 2005-04-15 Astrazeneca Ab A novel crystalline form of omeprazole
IL142703A (en) 1998-11-10 2006-04-10 Astrazeneca Ab Crystalline form of omeprazole
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SE9804003D0 (sv) 1998-11-23 1998-11-23 Astra Ab A method of producing drug particles
SE9900274D0 (sv) 1999-01-28 1999-01-28 Astra Ab New compound
JP2000344739A (ja) * 1999-06-01 2000-12-12 Sumitomo Chem Co Ltd Ｎ−保護−アゼチジン−２−カルボン酸の製造方法
TWI289557B (en) 1999-06-17 2007-11-11 Takeda Chemical Industries Ltd A crystal of a hydrate of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl]methyl]sulfinyl]-1H-benzimidazole
SE0000774D0 (sv) * 2000-03-08 2000-03-08 Astrazeneca Ab New formulation
SE0000773D0 (sv) * 2000-03-08 2000-03-08 Astrazeneca Ab New formulation
CN100562318C (zh) * 2000-05-15 2009-11-25 武田药品工业株式会社 晶体的制备方法
GB0016040D0 (en) * 2000-06-29 2000-08-23 Glaxo Group Ltd Novel process for preparing crystalline particles
AU2001276721A1 (en) 2000-08-04 2002-02-18 Takeda Chemical Industries Ltd. Salts of benzimidazole compound and use thereof
SI20875A (sl) 2001-04-25 2002-10-31 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Kristalna oblika omeprazola
US8206741B2 (en) 2001-06-01 2012-06-26 Pozen Inc. Pharmaceutical compositions for the coordinated delivery of NSAIDs
IL159129A0 (en) 2001-06-01 2004-05-12 Pozen Inc PHARMACEUTICAL COMPOSITIONS FOR THE COORDINATED DELIVERY OF NSAIDs
GB2376231A (en) 2001-06-06 2002-12-11 Cipla Ltd Benzimidazole-cyclodextrin inclusion complex
SE0102993D0 (sv) 2001-09-07 2001-09-07 Astrazeneca Ab New self emulsifying drug delivery system
CA2491118A1 (en) * 2002-06-27 2004-01-08 Dr. Reddy's Laboratories Limited A process for preparation of optically pure or optically enriched sulfoxide compounds, including amorphous esomeprazole and salts thereof
US7169793B2 (en) 2002-06-27 2007-01-30 Dr. Reddy's Laboratories Limited Process for preparation of optically pure or optically enriched sulfoxide compounds, including amorphous esomeprazole and salts thereof
WO2004020436A1 (en) * 2002-08-30 2004-03-11 Reddy's Laboratories Limited Amorphous hydrates of esomeprazole magnesium and process for the preparation thereof
AU2003273000A1 (en) 2002-10-16 2004-05-04 Takeda Pharmaceutical Company Limited Stable solid preparations
US20040235903A1 (en) * 2002-10-22 2004-11-25 Khanna Mahavir Singh Amorphous form of esomeprazole salts
US20040242642A1 (en) * 2002-11-18 2004-12-02 Dr. Reddy's Laboratories Limited Crystalline esomeprazole compounds and process for the preparation thereof
MXPA05009183A (es) * 2003-02-28 2005-10-20 Ranbaxy Lab Ltd Polimorfos de s-omeprazol.
JP4787017B2 (ja) * 2003-03-24 2011-10-05 エーザイ・アール・アンド・ディー・マネジメント株式会社 スルホキシド誘導体またはその塩のアモルファスの製造方法
CN1842525A (zh) * 2003-05-05 2006-10-04 兰贝克赛实验室有限公司 苯并咪唑衍生物的钡盐
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US20090298884A1 (en) * 2005-05-06 2009-12-03 Glenmark Generics Ltd. Esomeprazole Strontium Salt, Process For Its Preparation and Pharmaceutical Compositions Containing Same
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US7576219B2 (en) 2005-10-26 2009-08-18 Hanmi Pharm. Co., Ltd Crystalline S-omeprazole strontium hydrate, method for preparing same, and pharmaceutical composition containing same
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BRPI0619158A2 (pt) * 2005-12-05 2011-09-20 Astrazeneca Ab processo para preparar forma que não que não seja sal de esomeprazol, composto, formulação farmacêutica, e, método de tratamento
EP1801110A1 (en) 2005-12-22 2007-06-27 KRKA, tovarna zdravil, d.d., Novo mesto Esomeprazole arginine salt
SI1973896T1 (sl) 2005-12-28 2009-08-31 Union Quimico Farma Postopek priprave (S) - enantiomere omeprazola
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NZ588379A (en) 2008-03-10 2012-07-27 Takeda Pharmaceutical Crystal of benzimidazole compound
EP2143722A1 (en) 2008-07-09 2010-01-13 Lek Pharmaceuticals D.D. Process for preparation of esomeprazole sodium of high chemical purity and new forms of esomeprazole sodium
AU2009290712A1 (en) 2008-09-09 2010-03-18 Astrazeneca Ab Method for delivering a pharmaceutical composition to patient in need thereof
EA201290026A1 (ru) 2009-06-25 2012-07-30 Астразенека Аб Способ лечения пациента, имеющего риск развития язвы, связанной с приемом нестероидных противовоспалительных средств (nsaid)
EP2510089B1 (en) 2009-12-08 2015-10-21 Codexis, Inc. Synthesis of prazole compounds
HUE037616T2 (hu) 2010-12-08 2018-09-28 Codexis Inc Biokatalizátorok és eljárások armodafinil szintéziséhez
EA028049B1 (ru) 2011-12-28 2017-10-31 Поузен Инк. Улучшенные композиции и способы доставки омепразола и ацетилсалициловой кислоты
RU2501549C1 (ru) 2012-08-30 2013-12-20 Авва Девелопмент Лтд Фармацевтическая композиция для лечения гастроэзофагеальной рефлюксной болезни
CN107043367A (zh) * 2017-05-26 2017-08-15 重庆莱美隆宇药业有限公司 一种中性s‑奥美拉唑的干燥工艺
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Also Published As

Publication number Publication date
CN1241183A (zh) 2000-01-12
EE9900259A (et) 2000-02-15
PL334297A1 (en) 2000-02-14
RS49685B (sr) 2007-11-15
IS1981B (is) 2005-01-14
ES2194231T3 (es) 2003-11-16
IL130450A0 (en) 2000-06-01
PL190377B1 (pl) 2005-12-30
EE03923B1 (et) 2002-12-16
DK0946547T3 (da) 2003-06-30
ID21850A (id) 1999-08-05
ATE236898T1 (de) 2003-04-15
CN1109684C (zh) 2003-05-28
AU5502698A (en) 1998-07-17
MY117032A (en) 2004-04-30
HUP0001547A3 (en) 2002-06-28
YU28199A (sh) 2002-03-18
NZ336024A (en) 2001-02-23
WO1998028294A1 (en) 1998-07-02
SA97180739B1 (ar) 2006-05-20
AR010361A1 (es) 2000-06-07
HK1022909A1 (en) 2000-08-25
RU2184734C2 (ru) 2002-07-10
CZ294784B6 (cs) 2005-03-16
CA2274076C (en) 2008-09-30
HU227589B1 (en) 2011-09-28
JP2001507025A (ja) 2001-05-29
ZA9711046B (en) 1998-06-22
CA2274076A1 (en) 1998-07-02
BR9714059A (pt) 2000-05-09
NO993068L (no) 1999-06-21
SE9604793D0 (sv) 1996-12-20
NO993068D0 (no) 1999-06-21
AU730129B2 (en) 2001-02-22
DE69720774D1 (de) 2003-05-15
KR20000069595A (ko) 2000-11-25
IS5070A (is) 1999-06-07
SK285151B6 (sk) 2006-07-07
HUP0001547A2 (hu) 2002-05-29
HU0001547D0 (enExample) 2002-05-29
CZ220299A3 (cs) 2000-02-16
UA55436C2 (uk) 2003-04-15
EP0946547B1 (en) 2003-04-09
SK76599A3 (en) 1999-12-10
NO317191B1 (no) 2004-09-13
TW538039B (en) 2003-06-21
EG24414A (en) 2009-05-25
US6162816A (en) 2000-12-19
SE9604793L (sv) 1998-06-21
TR199901410T2 (xx) 1999-08-23
SI0946547T1 (en) 2003-10-31
PT946547E (pt) 2003-07-31
JP4402174B2 (ja) 2010-01-20
DE69720774T2 (de) 2004-02-05
EP0946547A1 (en) 1999-10-06

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