RU92004542A - Ароматические амидиновые производные и антикоагулирующее средство - Google Patents

Ароматические амидиновые производные и антикоагулирующее средство

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Publication number
RU92004542A
RU92004542A RU92004542/04A RU92004542A RU92004542A RU 92004542 A RU92004542 A RU 92004542A RU 92004542/04 A RU92004542/04 A RU 92004542/04A RU 92004542 A RU92004542 A RU 92004542A RU 92004542 A RU92004542 A RU 92004542A
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RU
Russia
Prior art keywords
group
optionally
aromatic
amidinum
derivatives
Prior art date
Application number
RU92004542/04A
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English (en)
Other versions
RU2139851C1 (ru
Inventor
Нагахара Такаясу
Каная Наоаки
Инамуре Казуе
Екояма Юкио
Original Assignee
Дайити Фармасьютикал Ко., Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Дайити Фармасьютикал Ко., Лтд. filed Critical Дайити Фармасьютикал Ко., Лтд.
Priority to TJ94000190A priority Critical patent/TJ229R3/xx
Publication of RU92004542A publication Critical patent/RU92004542A/ru
Application granted granted Critical
Publication of RU2139851C1 publication Critical patent/RU2139851C1/ru

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Claims (1)

  1. Предлагается ароматическое амидиновое производное, представленное общей формулой, или его соль:
    Figure 00000001

    где группа, представленная формулой
    Figure 00000002

    является группой, выбранной из индолила, бензофуранила, бензотиенила, бензимидазолила, бензоксазолила, бензотиазолила, нафтила, тетрагидронафтила, и инданила; X является простой связью, атомом кислорода, атомом серы, или карбонильной группой, а Y является насыщенной или ненасыщенной гетероциклической частью с 5 или 6 членами или циклической углеводородной частью, необязательно имеющей группу - заместителя, аминогруппой, необязательно имеющей группу - заместителя, или аминоалкильной группой, необязательно имеющей группу - заместителя, которое может быть полезно в качестве активного агента антикоагулирующего средства. Соединение обладает высокой антикоагулирующей способностью благодаря своей прекрасной FXa - ингибирующей активности.
RU92004542A 1991-10-31 1992-10-30 Ароматическое амидиновое производное и фармацевтическая композиция RU2139851C1 (ru)

Priority Applications (1)

Application Number Priority Date Filing Date Title
TJ94000190A TJ229R3 (en) 1991-10-31 1994-12-29 Aromatic amidine derivatives and salts thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP3-286088 1991-10-31
JP28608891 1991-10-31

Publications (2)

Publication Number Publication Date
RU92004542A true RU92004542A (ru) 1995-05-20
RU2139851C1 RU2139851C1 (ru) 1999-10-20

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US (4) US5576343A (ru)
EP (1) EP0540051B1 (ru)
JP (2) JP2879718B2 (ru)
KR (1) KR100205152B1 (ru)
CN (3) CN1049434C (ru)
AT (1) ATE136293T1 (ru)
AU (1) AU666137B2 (ru)
BG (1) BG63237B2 (ru)
CA (1) CA2081836C (ru)
CZ (1) CZ284381B6 (ru)
DE (1) DE69209615T2 (ru)
DK (1) DK0540051T3 (ru)
EE (1) EE03024B1 (ru)
ES (1) ES2088073T3 (ru)
FI (1) FI107923B (ru)
GR (1) GR3019832T3 (ru)
HK (1) HK1002999A1 (ru)
HR (1) HRP921147B1 (ru)
HU (1) HU221976B1 (ru)
IL (1) IL103564A (ru)
MX (1) MX9206295A (ru)
NO (1) NO302948B1 (ru)
NZ (1) NZ244936A (ru)
PL (1) PL170312B1 (ru)
RU (1) RU2139851C1 (ru)
SG (1) SG78251A1 (ru)
SK (1) SK327692A3 (ru)
TW (1) TW210998B (ru)
ZA (1) ZA928276B (ru)

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