SE9604744D0 - A modified coagulation agent - Google Patents

A modified coagulation agent

Info

Publication number
SE9604744D0
SE9604744D0 SE9604744A SE9604744A SE9604744D0 SE 9604744 D0 SE9604744 D0 SE 9604744D0 SE 9604744 A SE9604744 A SE 9604744A SE 9604744 A SE9604744 A SE 9604744A SE 9604744 D0 SE9604744 D0 SE 9604744D0
Authority
SE
Sweden
Prior art keywords
modified coagulation
coagulation agent
factor
crystals
crystalline
Prior art date
Application number
SE9604744A
Other languages
English (en)
Inventor
Joanna Chmielewska
Tomas Lundqvist
Erifili Mosiaglo
Derek Ogg
Original Assignee
Pharmacia & Upjohn Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Ab filed Critical Pharmacia & Upjohn Ab
Priority to SE9604744A priority Critical patent/SE9604744D0/sv
Publication of SE9604744D0 publication Critical patent/SE9604744D0/sv
Priority to AU55812/98A priority patent/AU5581298A/en
Priority to PCT/SE1997/002160 priority patent/WO1998028412A1/en
Priority to US08/994,328 priority patent/US6069234A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6432—Coagulation factor Xa (3.4.21.6)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21006—Coagulation factor Xa (3.4.21.6)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Catalysts (AREA)
SE9604744A 1996-12-20 1996-12-20 A modified coagulation agent SE9604744D0 (sv)

Priority Applications (4)

Application Number Priority Date Filing Date Title
SE9604744A SE9604744D0 (sv) 1996-12-20 1996-12-20 A modified coagulation agent
AU55812/98A AU5581298A (en) 1996-12-20 1997-12-18 Modified human factor xa
PCT/SE1997/002160 WO1998028412A1 (en) 1996-12-20 1997-12-18 MODIFIED HUMAN FACTOR Xa
US08/994,328 US6069234A (en) 1996-12-20 1997-12-19 Modified coagulation agent

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9604744A SE9604744D0 (sv) 1996-12-20 1996-12-20 A modified coagulation agent

Publications (1)

Publication Number Publication Date
SE9604744D0 true SE9604744D0 (sv) 1996-12-20

Family

ID=20405101

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9604744A SE9604744D0 (sv) 1996-12-20 1996-12-20 A modified coagulation agent

Country Status (4)

Country Link
US (1) US6069234A (sv)
AU (1) AU5581298A (sv)
SE (1) SE9604744D0 (sv)
WO (1) WO1998028412A1 (sv)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6936377B2 (en) * 2003-05-13 2005-08-30 C. Glen Wensley Card with embedded IC and electrochemical cell
US20040253520A1 (en) * 2003-05-13 2004-12-16 Wensley C. Glen Polyimide matrix electrolyte and improved batteries therefrom
US7390336B2 (en) * 2003-07-29 2008-06-24 Solicore, Inc. Polyimide-based lithium metal battery
KR101300453B1 (ko) * 2004-07-22 2013-08-27 솔리코어 인코포레이티드 향상된 전지 탭 및 패키징 설계
DK3078743T3 (da) 2007-09-28 2020-08-10 Portola Pharm Inc Antidoter til faktor xa-inhibitorer og fremgangsmåder til anvendelse af disse
WO2010056765A2 (en) * 2008-11-14 2010-05-20 Portola Pharmaceuticals, Inc. Antidotes for factor xa inhibitors and methods of using the same in combination with blood coagulating agents
PT2414517T (pt) 2009-03-30 2016-12-27 Portola Pharm Inc Antídotos para inibidores do fator xa e métodos de utilização dos mesmos
CN102625712B (zh) 2009-07-15 2017-07-25 博尔托拉制药公司 用于因子xa抑制剂的解毒剂的单位剂量制剂及其使用方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA928276B (en) * 1991-10-31 1993-05-06 Daiichi Seiyaku Co Aromatic amidine derivates and salts thereof.

Also Published As

Publication number Publication date
US6069234A (en) 2000-05-30
WO1998028412A1 (en) 1998-07-02
AU5581298A (en) 1998-07-17

Similar Documents

Publication Publication Date Title
DK274788A (da) Tetrazoler
NO2004008I1 (no) Patentets benevnelse
ES2146774T3 (es) Polimeros de ioneno que contienen aniones biologicamente activos.
TR200102799T2 (tr) Kemokin alıcı bağlayıcı heterosiklik bileşikler
HUP0000547A2 (hu) Cinkmentes inzulinkristályok pulmonáris kompozíciókhoz
TR200100075T2 (tr) 2-Kuinolon ihtiva eden farmasötik bileşimler
ATE253063T1 (de) 5-ht1f-agonisten
HUP9902099A2 (hu) Eljárások és készítmények, angiogenezis gátlására
EA200201119A1 (ru) Лиганды меланокортиновых рецепторов
DE69826684D1 (de) Kovalent gebundenes n,o-carboxymethylchitosan und seine verwendungen
BG103558A (en) Sulphonic acid or sulphonylamino n-(heteroaralkyl)-azaheterocyclylamide compounds
IT1247945B (it) Agente avente attivita' batteriostatica e battericida
SE9604744D0 (sv) A modified coagulation agent
IT1298338B1 (it) Composizioni farmaceutiche per l'ulcera
TR200101547T2 (tr) Askomisinleri içeren topik kompozisyonlar
EA200100141A1 (ru) Терапевтическая композиция на основе изофлавоноидов для применения в лечении опухолей цитотоксическими агентами
EA200000092A1 (ru) Противоаллергические средства
ATE441642T1 (de) Hydantoin derivate mit affinität für somatostatin rezeptoren
DK0669834T3 (da) Anvendelse af topisk påført faktor Xlll til inhibering af blødning
DE69409961T2 (de) Triarylethylenderivate zur therapeutischen verwendung
TR200102502T2 (tr) Trombin reseptör modülatörleri olarak yararlı sübstitüe edilmiş heterosiklik açil-tripeptidler.
EA200100150A1 (ru) Биспиперидины в качестве противотромботических агентов
FR2720938B1 (fr) Composition dermato-cosmétologique et son utilisation.
EA200100151A1 (ru) Производные пиперазинона и их применение
FI960588A0 (sv) Tiokarbamoylföreningar användbara som mikrobicider