RU2481336C2 - Циклопента(d)пиримидины в качестве ингибиторов протеинкиназ акт - Google Patents

Циклопента(d)пиримидины в качестве ингибиторов протеинкиназ акт Download PDF

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RU2481336C2
RU2481336C2 RU2009103899/04A RU2009103899A RU2481336C2 RU 2481336 C2 RU2481336 C2 RU 2481336C2 RU 2009103899/04 A RU2009103899/04 A RU 2009103899/04A RU 2009103899 A RU2009103899 A RU 2009103899A RU 2481336 C2 RU2481336 C2 RU 2481336C2
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Russia
Prior art keywords
methyl
cyclopenta
dihydro
piperazin
dihydrochloride
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RU2009103899/04A
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Russian (ru)
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RU2009103899A (ru
Inventor
Ян С. МИТЧЕЛ
Джеймс Ф. БЛЭЙК
Руи КСУ
Николас К. КАЛЛАН
Денгминг КСИАО
Кит Ли СПЕНСЕР
Йозеф Р. БЕНКСИК
Дзун ЛИАНГ
Брайан САФИНА
Цзун ЛИ
Кристин ЧАБОТ
Илай М. УОЛЛЕС
Анна Л. БАНКА
Стивен Т. ШЛЕХТЕР
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Эррэй Биофарма Инк.
Дженентек, Инк.
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Application filed by Эррэй Биофарма Инк., Дженентек, Инк. filed Critical Эррэй Биофарма Инк.
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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RU2009103899/04A 2006-07-06 2007-07-05 Циклопента(d)пиримидины в качестве ингибиторов протеинкиназ акт RU2481336C2 (ru)

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US81876206P 2006-07-06 2006-07-06
US60/818,762 2006-07-06
PCT/US2007/072876 WO2008006032A1 (en) 2006-07-06 2007-07-05 Cyclopenta [d] pyrimidines as akt protein kinase inhibitors

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RU2009103899A RU2009103899A (ru) 2010-08-20
RU2481336C2 true RU2481336C2 (ru) 2013-05-10

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US (3) US8003651B2 (https=)
EP (1) EP2049500B1 (https=)
JP (3) JP5268904B2 (https=)
KR (2) KR101527232B1 (https=)
CN (2) CN101631778B (https=)
AR (1) AR061844A1 (https=)
AT (1) ATE523499T1 (https=)
AU (1) AU2007269052B2 (https=)
BR (1) BRPI0713555A2 (https=)
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CL (1) CL2007001992A1 (https=)
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HR (1) HRP20110882T1 (https=)
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TW (1) TWI428335B (https=)
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UA95641C2 (xx) * 2006-07-06 2011-08-25 Эррей Биофарма Инк. Гідроксильовані піримідильні циклопентани як інгібітори акт протеїнкінази$гидроксилированные пиримидильные циклопентаны как ингибиторы акт протеинкиназы
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