RU2218153C2 - Драже, имеющее ядро, покрытое противогрибковым средством и полимером - Google Patents

Драже, имеющее ядро, покрытое противогрибковым средством и полимером Download PDF

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Publication number
RU2218153C2
RU2218153C2 RU99112123/15A RU99112123A RU2218153C2 RU 2218153 C2 RU2218153 C2 RU 2218153C2 RU 99112123/15 A RU99112123/15 A RU 99112123/15A RU 99112123 A RU99112123 A RU 99112123A RU 2218153 C2 RU2218153 C2 RU 2218153C2
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Russia
Prior art keywords
polymer
dragee
itraconazole
water
soluble polymer
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RU99112123/15A
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English (en)
Russian (ru)
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RU99112123A (ru
Inventor
Роже Петрус Гереберн ВАНДЕКРУЙС
КОНДЕ Валентэн Флоран Виктор ДЕ
Поль Мари Виктор Жили
Йозеф Петерс
Original Assignee
Жансен Фармасетика Н.В.
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Publication of RU99112123A publication Critical patent/RU99112123A/ru
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Publication of RU2218153C2 publication Critical patent/RU2218153C2/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds

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  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
RU99112123/15A 1997-03-26 1998-03-18 Драже, имеющее ядро, покрытое противогрибковым средством и полимером RU2218153C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97200914.6 1997-03-26
EP97200914 1997-03-26

Publications (2)

Publication Number Publication Date
RU99112123A RU99112123A (ru) 2001-04-20
RU2218153C2 true RU2218153C2 (ru) 2003-12-10

Family

ID=8228147

Family Applications (1)

Application Number Title Priority Date Filing Date
RU99112123/15A RU2218153C2 (ru) 1997-03-26 1998-03-18 Драже, имеющее ядро, покрытое противогрибковым средством и полимером

Country Status (30)

Country Link
EP (1) EP0969821B1 (https=)
JP (1) JP3608800B2 (https=)
KR (1) KR100520936B1 (https=)
CN (1) CN1206984C (https=)
AP (1) AP1227A (https=)
AT (1) ATE241969T1 (https=)
AU (1) AU734248B2 (https=)
BG (1) BG64434B1 (https=)
BR (1) BR9806174A (https=)
CA (1) CA2269501C (https=)
CY (1) CY2384B1 (https=)
CZ (1) CZ295502B6 (https=)
DE (1) DE69815316T2 (https=)
DK (1) DK0969821T3 (https=)
EE (1) EE03904B1 (https=)
ES (1) ES2201485T3 (https=)
HU (1) HU224217B1 (https=)
ID (1) ID21477A (https=)
IL (1) IL129575A (https=)
NO (1) NO325102B1 (https=)
NZ (1) NZ335364A (https=)
OA (1) OA11162A (https=)
PL (1) PL190566B1 (https=)
PT (1) PT969821E (https=)
RU (1) RU2218153C2 (https=)
SI (1) SI0969821T1 (https=)
SK (1) SK284813B6 (https=)
TR (1) TR199900990T2 (https=)
UA (1) UA60318C2 (https=)
WO (1) WO1998042318A1 (https=)

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EA009590B1 (ru) 2001-05-11 2008-02-28 Тиботек Фармасьютикалз Лтд. 2-аминобензоксазолсульфонамидные ингибиторы вич-протеазы широкого спектра
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JP4578101B2 (ja) 2001-12-21 2010-11-10 テイボテク・フアーマシユーチカルズ・リミテツド 幅広いスペクトルのｈｉｖプロテアーゼ阻害剤である複素環置換フェニル含有スルホンアミド
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JP4681296B2 (ja) 2002-08-14 2011-05-11 テイボテク・フアーマシユーチカルズ・リミテツド スペクトルの広い置換オキシインドールスルホンアミドｈｉｖプロテアーゼ阻害剤
KR100557680B1 (ko) * 2002-11-23 2006-03-07 한국유나이티드제약 주식회사 이트라코나졸의 용해도 개선을 위한 펠렛제제 및 그제조방법
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UA84020C2 (ru) 2003-09-11 2008-09-10 Тиботек Фармасьютикелз Лтд. Ингибитор проникновения вируса вил
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USH672H (en) * 1986-12-31 1989-09-05 E. R. Squibb & Sons, Inc. Stable antifungal capsule formulation
US5366733A (en) * 1988-12-22 1994-11-22 American Cyanamid Company Method for the treatment of periodontal disease by sustained delivery of a therapeutic agent to the periodontal pocket, and composition of matter therefor

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CA2258683C (en) * 1996-06-28 2007-07-31 Schering Corporation Oral composition comprising a triazole antifungal compound

Patent Citations (2)

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USH672H (en) * 1986-12-31 1989-09-05 E. R. Squibb & Sons, Inc. Stable antifungal capsule formulation
US5366733A (en) * 1988-12-22 1994-11-22 American Cyanamid Company Method for the treatment of periodontal disease by sustained delivery of a therapeutic agent to the periodontal pocket, and composition of matter therefor

Also Published As

Publication number Publication date
TR199900990T2 (xx) 1999-10-21
HU224217B1 (hu) 2005-06-28
EE9900453A (et) 2000-04-17
IL129575A (en) 2004-06-20
EP0969821B1 (en) 2003-06-04
EP0969821A1 (en) 2000-01-12
EE03904B1 (et) 2002-12-16
JP2001520663A (ja) 2001-10-30
CZ139899A3 (cs) 1999-10-13
KR100520936B1 (ko) 2005-10-17
ATE241969T1 (de) 2003-06-15
SI0969821T1 (en) 2003-10-31
BG64434B1 (en) 2005-02-28
CN1244796A (zh) 2000-02-16
NZ335364A (en) 2000-08-25
ID21477A (id) 1999-06-17
NO992114D0 (no) 1999-04-30
SK54499A3 (en) 2000-01-18
CA2269501C (en) 2005-11-08
IL129575A0 (en) 2000-02-29
PL335542A1 (en) 2000-04-25
AP9901516A0 (en) 1999-06-30
PT969821E (pt) 2003-10-31
BR9806174A (pt) 1999-10-19
CA2269501A1 (en) 1998-10-01
KR20000052971A (ko) 2000-08-25
CN1206984C (zh) 2005-06-22
BG103356A (en) 2000-03-31
JP3608800B2 (ja) 2005-01-12
NO992114L (no) 1999-08-26
OA11162A (en) 2003-04-16
HUP0002056A2 (hu) 2000-12-28
CY2384B1 (en) 2004-06-04
DE69815316T2 (de) 2004-04-29
DE69815316D1 (de) 2003-07-10
AP1227A (en) 2003-11-24
NO325102B1 (no) 2008-02-04
PL190566B1 (pl) 2005-12-30
CZ295502B6 (cs) 2005-08-17
HUP0002056A3 (en) 2001-01-29
UA60318C2 (uk) 2003-10-15
SK284813B6 (sk) 2005-12-01
WO1998042318A1 (en) 1998-10-01
DK0969821T3 (da) 2003-09-15
AU7210798A (en) 1998-10-20
HK1022840A1 (en) 2000-08-25
AU734248B2 (en) 2001-06-07
ES2201485T3 (es) 2004-03-16

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