SI0969821T1 - Pellets having a core coated with an antifungal and a polymer - Google Patents

Pellets having a core coated with an antifungal and a polymer

Info

Publication number
SI0969821T1
SI0969821T1 SI9830489T SI9830489T SI0969821T1 SI 0969821 T1 SI0969821 T1 SI 0969821T1 SI 9830489 T SI9830489 T SI 9830489T SI 9830489 T SI9830489 T SI 9830489T SI 0969821 T1 SI0969821 T1 SI 0969821T1
Authority
SI
Slovenia
Prior art keywords
antifungal
pellets
polymer
core coated
coated
Prior art date
Application number
SI9830489T
Other languages
English (en)
Slovenian (sl)
Inventor
Roger Petrus Gerebern Vandecruys
Conde Valentin Florent Victor De
Paul Marie Victor Gilis
Jozef Peeters
Original Assignee
Janssen Pharmaceutica N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica N.V. filed Critical Janssen Pharmaceutica N.V.
Publication of SI0969821T1 publication Critical patent/SI0969821T1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
SI9830489T 1997-03-26 1998-03-18 Pellets having a core coated with an antifungal and a polymer SI0969821T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP97200914 1997-03-26
EP98919155A EP0969821B1 (en) 1997-03-26 1998-03-18 Pellets having a core coated with an antifungal and a polymer
PCT/EP1998/001773 WO1998042318A1 (en) 1997-03-26 1998-03-18 Pellets having a core coated with an antifungal and a polymer

Publications (1)

Publication Number Publication Date
SI0969821T1 true SI0969821T1 (en) 2003-10-31

Family

ID=8228147

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9830489T SI0969821T1 (en) 1997-03-26 1998-03-18 Pellets having a core coated with an antifungal and a polymer

Country Status (31)

Country Link
EP (1) EP0969821B1 (xx)
JP (1) JP3608800B2 (xx)
KR (1) KR100520936B1 (xx)
CN (1) CN1206984C (xx)
AP (1) AP1227A (xx)
AT (1) ATE241969T1 (xx)
AU (1) AU734248B2 (xx)
BG (1) BG64434B1 (xx)
BR (1) BR9806174A (xx)
CA (1) CA2269501C (xx)
CY (1) CY2384B1 (xx)
CZ (1) CZ295502B6 (xx)
DE (1) DE69815316T2 (xx)
DK (1) DK0969821T3 (xx)
EE (1) EE03904B1 (xx)
ES (1) ES2201485T3 (xx)
HK (1) HK1022840A1 (xx)
HU (1) HU224217B1 (xx)
ID (1) ID21477A (xx)
IL (1) IL129575A (xx)
NO (1) NO325102B1 (xx)
NZ (1) NZ335364A (xx)
OA (1) OA11162A (xx)
PL (1) PL190566B1 (xx)
PT (1) PT969821E (xx)
RU (1) RU2218153C2 (xx)
SI (1) SI0969821T1 (xx)
SK (1) SK284813B6 (xx)
TR (1) TR199900990T2 (xx)
UA (1) UA60318C2 (xx)
WO (1) WO1998042318A1 (xx)

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SI1104291T1 (sl) 1998-07-17 2006-02-28 Janssen Pharmaceutica Nv Pelete, ki imajo jedro oblozeno s fungicidom in polimerom
ES2157731B1 (es) * 1998-07-21 2002-05-01 Liconsa Liberacion Controlada Preparacion farmaceutica oral de un compuesto de actividad antifungica y procedimiento para su preparacion.
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US6663897B2 (en) * 2001-02-06 2003-12-16 Dsm Ip Assets B.V. Oral itraconazole formulations and methods of making the same
CZ304273B6 (cs) 2001-02-14 2014-02-12 Tibotec Pharmaceuticals Ltd. 2-(Substitovaná-amino)benzothiazolsulfonamidová sloučenina, způsob její přípravy a farmaceutická kompozice s jejím obsahem
NZ528954A (en) 2001-04-09 2005-04-29 Tibotec Pharm Ltd Broadspectrum 2-(substituted-amino)-benzoxazole sulfonamide HIV protease inhibitors
PL209029B1 (pl) 2001-05-11 2011-07-29 Tibotec Pharm Ltd Pochodne 2-aminobenzoksazolo-sulfonamidów jako inhibitory proteazy HIV, oraz kompozycje zawierające te związki
WO2002100407A1 (en) * 2001-06-12 2002-12-19 Smartrix Technologies Inc. Itraconazole granulations: pharmaceutical formulations for oral administration and method of preparing same
US8071133B2 (en) 2001-08-20 2011-12-06 Stiefel Laboratories, Inc. Oral dosage forms of water insoluble drugs and methods of making the same
BR0215260A (pt) 2001-12-21 2004-12-07 Tibotec Pharm Ltd Inibidores de hiv protease de sulfonamida contendo fenila substituìda heterocìclica de amplo espectro
MY142238A (en) 2002-03-12 2010-11-15 Tibotec Pharm Ltd Broadspectrum substituted benzimidazole sulfonamide hiv protease inhibitors
IL165043A0 (en) 2002-05-17 2005-12-18 Tibotec Pharm Ltd broadspectrum substituted benzisoxazole sulfonamide hiv protease inhibitors
MXPA05001792A (es) 2002-08-14 2005-04-25 Tibotec Pharm Ltd Oxindolsulfonamida sustituida como inhibidores de proteasa de virus de inmunodeficiencia humana de amplio espectro.
KR100557680B1 (ko) * 2002-11-23 2006-03-07 한국유나이티드제약 주식회사 이트라코나졸의 용해도 개선을 위한 펠렛제제 및 그제조방법
SI1438960T2 (sl) * 2003-01-14 2013-04-30 Cimex Pharma Ag Sestavek itrakonazola, dispergiranega v hidrofilnem polimeru, z izboljšano biorazpoložljivostjo
ES2283725T5 (es) * 2003-01-14 2014-11-28 Acino Pharma Ag Composición bioequivalente de itraconazol dispersada en un polímero hidrófilo
NZ545145A (en) * 2003-08-06 2009-07-31 Nirmal Mulye Pharmaceutical composition containing water soluble drug
MXPA06002780A (es) 2003-09-11 2006-06-14 Tibotec Pharm Ltd Inhibidores de entrada del virus de vih.
EP1568369A1 (en) 2004-02-23 2005-08-31 Boehringer Ingelheim Vetmedica Gmbh Use of meloxicam for the treatment of respiratory diseases in pigs
AR048650A1 (es) 2004-05-04 2006-05-10 Tibotec Pharm Ltd Derivados de (1,10b-dihidro-2-(aminocarbonil-fenil)-5h-pirazolo[1,5 c][1,3]benzoxazin-5-il)fenil metanona como inhibidores de la replicacion viral del vih
CN1997363B (zh) 2004-05-07 2012-03-28 塞阔伊亚药品公司 抗耐药性反转录病毒蛋白酶抑制剂
ES2351702T3 (es) 2004-05-17 2011-02-09 Tibotec Pharmaceuticals 1-fenil-1,5-dihidro-pirido[3,2-b]indol-2-onas 6,7,8,9-sustituidas útiles como agentes farmacéuticos antiinfecciosos.
KR20070015608A (ko) 2004-05-17 2007-02-05 티보텍 파마슈티칼즈 리미티드 1-헤테로사이클일-1,5-디히드로-피리도[3,2-ｂ]인돌-2-온
US7622582B2 (en) 2004-05-17 2009-11-24 Tibotec Bvba Derivatives of 1-phenyl-benzofuro[3,2]pyridin-2(1H)-one
US7994187B2 (en) 2006-04-03 2011-08-09 Tibotec Pharmaceuticals Ltd. HIV inhibiting 3,4-dihydro-imidazo[4,5-B]pyridin-5-ones
BRPI0716481A2 (pt) * 2006-09-04 2014-03-18 Panacea Biotec Ltd Tecnologia de liberação flutuante programável
KR100809903B1 (ko) * 2006-09-05 2008-03-06 주식회사유한양행 안정화된 클로피도그렐-함유 입자, 그의 제조방법, 및 이를포함하는 약학 조성물
CN101283984B (zh) * 2007-04-12 2010-05-26 永胜药品工业股份有限公司 高生物使用率的经杀真菌剂和聚合物涂覆的核心微粒状物
JP2008280254A (ja) * 2007-05-08 2008-11-20 Everest Pharm Industrial Co Ltd 生体に使用される比率が高い、殺菌剤と重合物を塗粧してる核心微粒状物
US8313527B2 (en) 2007-11-05 2012-11-20 Allergan, Inc. Soft prosthesis shell texturing method
JP5745855B2 (ja) 2007-11-28 2015-07-08 セコイア、ファーマシューティカルズ、インコーポレイテッドＳｅｑｕｏｉａ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ． シトクロムｐ４５０ ２ｄ６を阻害するための組成物および方法
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US9050184B2 (en) 2008-08-13 2015-06-09 Allergan, Inc. Dual plane breast implant
US8877822B2 (en) 2010-09-28 2014-11-04 Allergan, Inc. Porogen compositions, methods of making and uses
US8685296B2 (en) * 2010-05-11 2014-04-01 Allergan, Inc. Porogen compositions, method of making and uses
US9205577B2 (en) 2010-02-05 2015-12-08 Allergan, Inc. Porogen compositions, methods of making and uses
US9138309B2 (en) 2010-02-05 2015-09-22 Allergan, Inc. Porous materials, methods of making and uses
SG174658A1 (en) 2010-04-01 2011-10-28 Theravida Inc Pharmaceutical formulations for the treatment of overactive bladder
US11202853B2 (en) 2010-05-11 2021-12-21 Allergan, Inc. Porogen compositions, methods of making and uses
US8679279B2 (en) 2010-11-16 2014-03-25 Allergan, Inc. Methods for creating foam-like texture
CN102100678B (zh) * 2011-02-18 2012-10-17 天津力生制药股份有限公司 伊曲康唑硫酸盐微丸及其制备方法
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US10092392B2 (en) 2014-05-16 2018-10-09 Allergan, Inc. Textured breast implant and methods of making same
CN108697688A (zh) * 2016-01-20 2018-10-23 塞拉维达公司 用于治疗多汗症的方法和组合物
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CN114767636B (zh) * 2022-04-11 2023-11-07 苏州中化药品工业有限公司 伊曲康唑微丸、制备方法及伊曲康唑微丸胶囊

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DE3346123A1 (de) * 1983-12-21 1985-06-27 Janssen Pharmaceutica, N.V., Beerse Pharmazeutische praeparate von in wasser schwerloeslichen oder instabilen arzneistoffen und verfahren zu ihrer herstellung
GB8506792D0 (en) * 1985-03-15 1985-04-17 Janssen Pharmaceutica Nv Derivatives of y-cyclodextrin
PH30929A (en) * 1992-09-03 1997-12-23 Janssen Pharmaceutica Nv Beads having a core coated with an antifungal and a polymer.
HUP9903869A3 (en) * 1996-06-28 2000-07-28 Schering Corp Oral composition comprising a triazole antifungal compound

Also Published As

Publication number Publication date
CZ295502B6 (cs) 2005-08-17
NZ335364A (en) 2000-08-25
EP0969821B1 (en) 2003-06-04
EP0969821A1 (en) 2000-01-12
HUP0002056A2 (hu) 2000-12-28
AP1227A (en) 2003-11-24
PL190566B1 (pl) 2005-12-30
CZ139899A3 (cs) 1999-10-13
PT969821E (pt) 2003-10-31
AU734248B2 (en) 2001-06-07
BR9806174A (pt) 1999-10-19
EE03904B1 (et) 2002-12-16
CA2269501A1 (en) 1998-10-01
HU224217B1 (hu) 2005-06-28
IL129575A0 (en) 2000-02-29
CN1206984C (zh) 2005-06-22
PL335542A1 (en) 2000-04-25
NO992114L (no) 1999-08-26
HK1022840A1 (en) 2000-08-25
AP9901516A0 (en) 1999-06-30
OA11162A (en) 2003-04-16
DK0969821T3 (da) 2003-09-15
JP2001520663A (ja) 2001-10-30
ID21477A (id) 1999-06-17
WO1998042318A1 (en) 1998-10-01
SK54499A3 (en) 2000-01-18
DE69815316T2 (de) 2004-04-29
ES2201485T3 (es) 2004-03-16
CN1244796A (zh) 2000-02-16
DE69815316D1 (de) 2003-07-10
UA60318C2 (uk) 2003-10-15
NO992114D0 (no) 1999-04-30
CY2384B1 (en) 2004-06-04
EE9900453A (et) 2000-04-17
TR199900990T2 (xx) 1999-10-21
KR100520936B1 (ko) 2005-10-17
BG103356A (en) 2000-03-31
KR20000052971A (ko) 2000-08-25
NO325102B1 (no) 2008-02-04
ATE241969T1 (de) 2003-06-15
SK284813B6 (sk) 2005-12-01
IL129575A (en) 2004-06-20
BG64434B1 (en) 2005-02-28
CA2269501C (en) 2005-11-08
AU7210798A (en) 1998-10-20
HUP0002056A3 (en) 2001-01-29
RU2218153C2 (ru) 2003-12-10
JP3608800B2 (ja) 2005-01-12

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