PL190566B1 - Peletka, zawierająca rdzeń pokryty itrakonazolem i polimerem i sposób jej wytwarzania oraz postać dawki farmaceutycznej - Google Patents
Peletka, zawierająca rdzeń pokryty itrakonazolem i polimerem i sposób jej wytwarzania oraz postać dawki farmaceutycznejInfo
- Publication number
- PL190566B1 PL190566B1 PL98335542A PL33554298A PL190566B1 PL 190566 B1 PL190566 B1 PL 190566B1 PL 98335542 A PL98335542 A PL 98335542A PL 33554298 A PL33554298 A PL 33554298A PL 190566 B1 PL190566 B1 PL 190566B1
- Authority
- PL
- Poland
- Prior art keywords
- polymer
- itraconazole
- pellets
- water
- cores
- Prior art date
Links
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- 239000003429 antifungal agent Substances 0.000 title claims abstract description 13
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- VHVPQPYKVGDNFY-DFMJLFEVSA-N 2-[(2r)-butan-2-yl]-4-[4-[4-[4-[[(2r,4s)-2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-1,2,4-triazol-3-one Chemical compound O=C1N([C@H](C)CC)N=CN1C1=CC=C(N2CCN(CC2)C=2C=CC(OC[C@@H]3O[C@](CN4N=CN=C4)(OC3)C=3C(=CC(Cl)=CC=3)Cl)=CC=2)C=C1 VHVPQPYKVGDNFY-DFMJLFEVSA-N 0.000 claims description 61
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP97200914 | 1997-03-26 | ||
| PCT/EP1998/001773 WO1998042318A1 (en) | 1997-03-26 | 1998-03-18 | Pellets having a core coated with an antifungal and a polymer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL335542A1 PL335542A1 (en) | 2000-04-25 |
| PL190566B1 true PL190566B1 (pl) | 2005-12-30 |
Family
ID=8228147
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL98335542A PL190566B1 (pl) | 1997-03-26 | 1998-03-18 | Peletka, zawierająca rdzeń pokryty itrakonazolem i polimerem i sposób jej wytwarzania oraz postać dawki farmaceutycznej |
Country Status (30)
| Country | Link |
|---|---|
| EP (1) | EP0969821B1 (https=) |
| JP (1) | JP3608800B2 (https=) |
| KR (1) | KR100520936B1 (https=) |
| CN (1) | CN1206984C (https=) |
| AP (1) | AP1227A (https=) |
| AT (1) | ATE241969T1 (https=) |
| AU (1) | AU734248B2 (https=) |
| BG (1) | BG64434B1 (https=) |
| BR (1) | BR9806174A (https=) |
| CA (1) | CA2269501C (https=) |
| CY (1) | CY2384B1 (https=) |
| CZ (1) | CZ295502B6 (https=) |
| DE (1) | DE69815316T2 (https=) |
| DK (1) | DK0969821T3 (https=) |
| EE (1) | EE03904B1 (https=) |
| ES (1) | ES2201485T3 (https=) |
| HU (1) | HU224217B1 (https=) |
| ID (1) | ID21477A (https=) |
| IL (1) | IL129575A (https=) |
| NO (1) | NO325102B1 (https=) |
| NZ (1) | NZ335364A (https=) |
| OA (1) | OA11162A (https=) |
| PL (1) | PL190566B1 (https=) |
| PT (1) | PT969821E (https=) |
| RU (1) | RU2218153C2 (https=) |
| SI (1) | SI0969821T1 (https=) |
| SK (1) | SK284813B6 (https=) |
| TR (1) | TR199900990T2 (https=) |
| UA (1) | UA60318C2 (https=) |
| WO (1) | WO1998042318A1 (https=) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI1104291T1 (sl) | 1998-07-17 | 2006-02-28 | Janssen Pharmaceutica Nv | Pelete, ki imajo jedro oblozeno s fungicidom in polimerom |
| ES2157731B1 (es) * | 1998-07-21 | 2002-05-01 | Liconsa Liberacion Controlada | Preparacion farmaceutica oral de un compuesto de actividad antifungica y procedimiento para su preparacion. |
| ES2251985T3 (es) | 1999-03-24 | 2006-05-16 | R.P. Scherer Technologies, Inc. | Particula granulada para mejorar la solubilidad acuosa de farmacos, y su procedimiento de preparacion. |
| KR100432949B1 (ko) * | 2000-06-13 | 2004-05-31 | 코오롱제약주식회사 | 생체이용율이 향상된 이트라코나졸의 분립체 조성물과이를 이용한 이트라코나졸 제제 및 그 제조방법 |
| US6663897B2 (en) * | 2001-02-06 | 2003-12-16 | Dsm Ip Assets B.V. | Oral itraconazole formulations and methods of making the same |
| US7659404B2 (en) | 2001-02-14 | 2010-02-09 | Tibotec Pharmaceuticals Ltd. | Broad spectrum 2-(substituted-amino)-benzothiazole sulfonamide HIV protease inhibitors |
| OA12464A (en) | 2001-04-09 | 2006-05-24 | Tibotec Pharm Ltd | Broadspectrum 2-(substituted-amino)-benzoxazole sulfonamide HIV protease inhibitors. |
| WO2002092595A1 (en) | 2001-05-11 | 2002-11-21 | Tibotec Pharmaceuticals Ltd. | Broadspectrum 2-amino-benzoxazole sulfonamide hiv protease inhibitors |
| WO2002100407A1 (en) * | 2001-06-12 | 2002-12-19 | Smartrix Technologies Inc. | Itraconazole granulations: pharmaceutical formulations for oral administration and method of preparing same |
| US8071133B2 (en) | 2001-08-20 | 2011-12-06 | Stiefel Laboratories, Inc. | Oral dosage forms of water insoluble drugs and methods of making the same |
| MY138657A (en) | 2001-12-21 | 2009-07-31 | Tibotec Pharm Ltd | broadspectrum heterocyclic substituted phenyl containing sulfonamide hiv protease inhibitors |
| MY142238A (en) | 2002-03-12 | 2010-11-15 | Tibotec Pharm Ltd | Broadspectrum substituted benzimidazole sulfonamide hiv protease inhibitors |
| IL165043A0 (en) | 2002-05-17 | 2005-12-18 | Tibotec Pharm Ltd | broadspectrum substituted benzisoxazole sulfonamide hiv protease inhibitors |
| NZ538714A (en) | 2002-08-14 | 2007-03-30 | Tibotec Pharm Ltd | Broadspectrum substituted oxindole sulfonamide HIV protease inhibitors |
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1998
- 1998-03-18 SK SK544-99A patent/SK284813B6/sk not_active IP Right Cessation
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- 1998-03-18 PT PT98919155T patent/PT969821E/pt unknown
- 1998-03-18 ES ES98919155T patent/ES2201485T3/es not_active Expired - Lifetime
- 1998-03-18 SI SI9830489T patent/SI0969821T1/xx unknown
- 1998-03-18 EE EEP199900453A patent/EE03904B1/xx unknown
- 1998-03-18 WO PCT/EP1998/001773 patent/WO1998042318A1/en not_active Ceased
- 1998-03-18 RU RU99112123/15A patent/RU2218153C2/ru active
- 1998-03-18 JP JP54490198A patent/JP3608800B2/ja not_active Expired - Lifetime
- 1998-03-18 ID IDW990316A patent/ID21477A/id unknown
- 1998-03-18 AU AU72107/98A patent/AU734248B2/en not_active Expired
- 1998-03-18 AT AT98919155T patent/ATE241969T1/de active
- 1998-03-18 DE DE69815316T patent/DE69815316T2/de not_active Expired - Lifetime
- 1998-03-18 DK DK98919155T patent/DK0969821T3/da active
- 1998-03-18 HU HU0002056A patent/HU224217B1/hu active IP Right Grant
- 1998-03-18 BR BR9806174-7A patent/BR9806174A/pt not_active Application Discontinuation
- 1998-03-18 PL PL98335542A patent/PL190566B1/pl unknown
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- 1998-03-18 UA UA99042468A patent/UA60318C2/uk unknown
- 1998-03-18 KR KR10-1999-7003848A patent/KR100520936B1/ko not_active Expired - Lifetime
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1999
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