KR100520936B1 - 항진균제 및 중합체로 코팅된 코어를 갖는 펠릿제 - Google Patents
항진균제 및 중합체로 코팅된 코어를 갖는 펠릿제 Download PDFInfo
- Publication number
- KR100520936B1 KR100520936B1 KR10-1999-7003848A KR19997003848A KR100520936B1 KR 100520936 B1 KR100520936 B1 KR 100520936B1 KR 19997003848 A KR19997003848 A KR 19997003848A KR 100520936 B1 KR100520936 B1 KR 100520936B1
- Authority
- KR
- South Korea
- Prior art keywords
- coating
- pellets
- itraconazole
- polymer
- pellet
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
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- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP97200914.6 | 1997-03-26 | ||
| EP97200914 | 1997-03-26 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20000052971A KR20000052971A (ko) | 2000-08-25 |
| KR100520936B1 true KR100520936B1 (ko) | 2005-10-17 |
Family
ID=8228147
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR10-1999-7003848A Expired - Lifetime KR100520936B1 (ko) | 1997-03-26 | 1998-03-18 | 항진균제 및 중합체로 코팅된 코어를 갖는 펠릿제 |
Country Status (30)
| Country | Link |
|---|---|
| EP (1) | EP0969821B1 (https=) |
| JP (1) | JP3608800B2 (https=) |
| KR (1) | KR100520936B1 (https=) |
| CN (1) | CN1206984C (https=) |
| AP (1) | AP1227A (https=) |
| AT (1) | ATE241969T1 (https=) |
| AU (1) | AU734248B2 (https=) |
| BG (1) | BG64434B1 (https=) |
| BR (1) | BR9806174A (https=) |
| CA (1) | CA2269501C (https=) |
| CY (1) | CY2384B1 (https=) |
| CZ (1) | CZ295502B6 (https=) |
| DE (1) | DE69815316T2 (https=) |
| DK (1) | DK0969821T3 (https=) |
| EE (1) | EE03904B1 (https=) |
| ES (1) | ES2201485T3 (https=) |
| HU (1) | HU224217B1 (https=) |
| ID (1) | ID21477A (https=) |
| IL (1) | IL129575A (https=) |
| NO (1) | NO325102B1 (https=) |
| NZ (1) | NZ335364A (https=) |
| OA (1) | OA11162A (https=) |
| PL (1) | PL190566B1 (https=) |
| PT (1) | PT969821E (https=) |
| RU (1) | RU2218153C2 (https=) |
| SI (1) | SI0969821T1 (https=) |
| SK (1) | SK284813B6 (https=) |
| TR (1) | TR199900990T2 (https=) |
| UA (1) | UA60318C2 (https=) |
| WO (1) | WO1998042318A1 (https=) |
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| BR9906712A (pt) * | 1998-07-17 | 2000-10-10 | Janssen Pharmaceutica Nv | Péletes que apresentam um núcleo revestido com um antifúngico e um polìmero |
| ES2157731B1 (es) * | 1998-07-21 | 2002-05-01 | Liconsa Liberacion Controlada | Preparacion farmaceutica oral de un compuesto de actividad antifungica y procedimiento para su preparacion. |
| ES2251985T3 (es) | 1999-03-24 | 2006-05-16 | R.P. Scherer Technologies, Inc. | Particula granulada para mejorar la solubilidad acuosa de farmacos, y su procedimiento de preparacion. |
| KR100432949B1 (ko) * | 2000-06-13 | 2004-05-31 | 코오롱제약주식회사 | 생체이용율이 향상된 이트라코나졸의 분립체 조성물과이를 이용한 이트라코나졸 제제 및 그 제조방법 |
| US6663897B2 (en) * | 2001-02-06 | 2003-12-16 | Dsm Ip Assets B.V. | Oral itraconazole formulations and methods of making the same |
| ES2275866T3 (es) | 2001-02-14 | 2007-06-16 | Tibotec Pharmaceuticals Ltd. | 2-(aminosustituido)-benzotiazol-sulfonamidas de amplio esprecto inhibidoras de la proteasa de vih. |
| AR035819A1 (es) | 2001-04-09 | 2004-07-14 | Tibotec Pharm Ltd | 2-(amino sustituido)-benzoxazol sulfonamidas, inhibidoras de la proteasa del hiv, composiciones farmaceuticas que comprenden dichos compuestos, metodo in vitro para inhibir la replicacion retroviral y uso de dichos compuestos en la fabricacion de medicamentos |
| EA009590B1 (ru) | 2001-05-11 | 2008-02-28 | Тиботек Фармасьютикалз Лтд. | 2-аминобензоксазолсульфонамидные ингибиторы вич-протеазы широкого спектра |
| WO2002100407A1 (en) * | 2001-06-12 | 2002-12-19 | Smartrix Technologies Inc. | Itraconazole granulations: pharmaceutical formulations for oral administration and method of preparing same |
| US8071133B2 (en) | 2001-08-20 | 2011-12-06 | Stiefel Laboratories, Inc. | Oral dosage forms of water insoluble drugs and methods of making the same |
| JP4578101B2 (ja) | 2001-12-21 | 2010-11-10 | テイボテク・フアーマシユーチカルズ・リミテツド | 幅広いスペクトルのｈｉｖプロテアーゼ阻害剤である複素環置換フェニル含有スルホンアミド |
| MY142238A (en) | 2002-03-12 | 2010-11-15 | Tibotec Pharm Ltd | Broadspectrum substituted benzimidazole sulfonamide hiv protease inhibitors |
| KR101019648B1 (ko) | 2002-05-17 | 2011-03-07 | 티보텍 파마슈티컬즈 | 광범위 스펙트럼의 치환된 벤즈이속사졸 설폰아미드ｈｉｖ 프로테아제 저해제 |
| JP4681296B2 (ja) | 2002-08-14 | 2011-05-11 | テイボテク・フアーマシユーチカルズ・リミテツド | スペクトルの広い置換オキシインドールスルホンアミドｈｉｖプロテアーゼ阻害剤 |
| KR100557680B1 (ko) * | 2002-11-23 | 2006-03-07 | 한국유나이티드제약 주식회사 | 이트라코나졸의 용해도 개선을 위한 펠렛제제 및 그제조방법 |
| DK1438961T4 (da) * | 2003-01-14 | 2014-11-17 | Acino Pharma Ag | Bioækvivalent sammensætning af itraconazol dispergeret i en hydrofil polymer |
| EP1438960B2 (en) * | 2003-01-14 | 2012-12-19 | Acino Pharma AG | Compostion of itraconazole dispersed in a hydrophilic polymer having enhanced bioavailability |
| WO2005013939A1 (en) | 2003-08-06 | 2005-02-17 | Nirmal Mulye | Pharmaceutical composition containing water soluble drug |
| UA84020C2 (ru) | 2003-09-11 | 2008-09-10 | Тиботек Фармасьютикелз Лтд. | Ингибитор проникновения вируса вил |
| EP1568369A1 (en) | 2004-02-23 | 2005-08-31 | Boehringer Ingelheim Vetmedica Gmbh | Use of meloxicam for the treatment of respiratory diseases in pigs |
| AR048650A1 (es) | 2004-05-04 | 2006-05-10 | Tibotec Pharm Ltd | Derivados de (1,10b-dihidro-2-(aminocarbonil-fenil)-5h-pirazolo[1,5 c][1,3]benzoxazin-5-il)fenil metanona como inhibidores de la replicacion viral del vih |
| EP2422781A1 (en) | 2004-05-07 | 2012-02-29 | Sequoia Pharmaceuticals, Inc. | Resistance-repellent retroviral protease inhibitors |
| CN1953982B (zh) | 2004-05-17 | 2011-07-06 | 泰博特克药品有限公司 | 4-取代-1,5-二氢-吡啶并[3,2-b]吲哚-2-酮 |
| TW200607503A (en) | 2004-05-17 | 2006-03-01 | Tibotec Pharm Ltd | 1-heterocyclyl-1, 5-dihydro-pyrido[3, 2-b]indol-2-ones |
| ES2351702T3 (es) | 2004-05-17 | 2011-02-09 | Tibotec Pharmaceuticals | 1-fenil-1,5-dihidro-pirido[3,2-b]indol-2-onas 6,7,8,9-sustituidas útiles como agentes farmacéuticos antiinfecciosos. |
| US7994187B2 (en) | 2006-04-03 | 2011-08-09 | Tibotec Pharmaceuticals Ltd. | HIV inhibiting 3,4-dihydro-imidazo[4,5-B]pyridin-5-ones |
| CA2661172A1 (en) * | 2006-09-04 | 2008-05-29 | Panacea Biotec Limited | Programmable buoyant delivery technology |
| KR100809903B1 (ko) * | 2006-09-05 | 2008-03-06 | 주식회사유한양행 | 안정화된 클로피도그렐-함유 입자, 그의 제조방법, 및 이를포함하는 약학 조성물 |
| CN101283984B (zh) * | 2007-04-12 | 2010-05-26 | 永胜药品工业股份有限公司 | 高生物使用率的经杀真菌剂和聚合物涂覆的核心微粒状物 |
| JP2008280254A (ja) * | 2007-05-08 | 2008-11-20 | Everest Pharm Industrial Co Ltd | 生体に使用される比率が高い、殺菌剤と重合物を塗粧してる核心微粒状物 |
| US8313527B2 (en) | 2007-11-05 | 2012-11-20 | Allergan, Inc. | Soft prosthesis shell texturing method |
| US8569364B2 (en) | 2007-11-28 | 2013-10-29 | Sequoia Pharmaceuticals, Inc. | 5-substituted benzofurans as inhibitors of cytochrome P450 2D6 |
| US8906647B2 (en) | 2008-02-21 | 2014-12-09 | Sequoia Pharmaceuticals, Inc. | Diamide inhibitors of cytochrome P450 |
| US9050184B2 (en) | 2008-08-13 | 2015-06-09 | Allergan, Inc. | Dual plane breast implant |
| US8877822B2 (en) | 2010-09-28 | 2014-11-04 | Allergan, Inc. | Porogen compositions, methods of making and uses |
| US9205577B2 (en) | 2010-02-05 | 2015-12-08 | Allergan, Inc. | Porogen compositions, methods of making and uses |
| US9138309B2 (en) | 2010-02-05 | 2015-09-22 | Allergan, Inc. | Porous materials, methods of making and uses |
| SG174658A1 (en) | 2010-04-01 | 2011-10-28 | Theravida Inc | Pharmaceutical formulations for the treatment of overactive bladder |
| JP5852640B2 (ja) * | 2010-05-11 | 2016-02-03 | アラーガン、インコーポレイテッドＡｌｌｅｒｇａｎ，Ｉｎｃｏｒｐｏｒａｔｅｄ | ポロゲン組成物、製造方法、および使用 |
| US11202853B2 (en) | 2010-05-11 | 2021-12-21 | Allergan, Inc. | Porogen compositions, methods of making and uses |
| US8679279B2 (en) | 2010-11-16 | 2014-03-25 | Allergan, Inc. | Methods for creating foam-like texture |
| CN102100678B (zh) * | 2011-02-18 | 2012-10-17 | 天津力生制药股份有限公司 | 伊曲康唑硫酸盐微丸及其制备方法 |
| CA2895083A1 (en) | 2012-12-13 | 2014-06-19 | Allergan, Inc. | Device and method for making a variable surface breast implant |
| US10092392B2 (en) | 2014-05-16 | 2018-10-09 | Allergan, Inc. | Textured breast implant and methods of making same |
| WO2017127073A1 (en) * | 2016-01-20 | 2017-07-27 | Theravida, Inc. | Methods and compositions for treating hyperhidrosis |
| PT3781132T (pt) * | 2018-04-16 | 2024-05-16 | Pfizer | Formulações de apixabano |
| CN114767636B (zh) * | 2022-04-11 | 2023-11-07 | 苏州中化药品工业有限公司 | 伊曲康唑微丸、制备方法及伊曲康唑微丸胶囊 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994005263A1 (en) * | 1992-09-03 | 1994-03-17 | Janssen Pharmaceutica N.V. | Beads having a core coated with an antifungal and a polymer |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3346123A1 (de) * | 1983-12-21 | 1985-06-27 | Janssen Pharmaceutica, N.V., Beerse | Pharmazeutische praeparate von in wasser schwerloeslichen oder instabilen arzneistoffen und verfahren zu ihrer herstellung |
| GB8506792D0 (en) * | 1985-03-15 | 1985-04-17 | Janssen Pharmaceutica Nv | Derivatives of y-cyclodextrin |
| USH672H (en) * | 1986-12-31 | 1989-09-05 | E. R. Squibb & Sons, Inc. | Stable antifungal capsule formulation |
| DE68915132T2 (de) * | 1988-12-22 | 1994-12-08 | American Cyanamid Co., Wayne, N.J. | Verfahren zur Behandlung von Periodontitis durch protrahierte Wirkstoffabgabe von Arzneimitteln in der Zahnhöhle, Zusammensetzung davon und Vorrichtung zur Verabreichung. |
| CA2258683C (en) * | 1996-06-28 | 2007-07-31 | Schering Corporation | Oral composition comprising a triazole antifungal compound |
-
1998
- 1998-03-18 JP JP54490198A patent/JP3608800B2/ja not_active Expired - Lifetime
- 1998-03-18 KR KR10-1999-7003848A patent/KR100520936B1/ko not_active Expired - Lifetime
- 1998-03-18 CZ CZ19991398A patent/CZ295502B6/cs not_active IP Right Cessation
- 1998-03-18 TR TR1999/00990T patent/TR199900990T2/xx unknown
- 1998-03-18 IL IL12957598A patent/IL129575A/en not_active IP Right Cessation
- 1998-03-18 AP APAP/P/1999/001516A patent/AP1227A/en active
- 1998-03-18 UA UA99042468A patent/UA60318C2/uk unknown
- 1998-03-18 RU RU99112123/15A patent/RU2218153C2/ru active
- 1998-03-18 ES ES98919155T patent/ES2201485T3/es not_active Expired - Lifetime
- 1998-03-18 EE EEP199900453A patent/EE03904B1/xx unknown
- 1998-03-18 CN CNB988020181A patent/CN1206984C/zh not_active Expired - Lifetime
- 1998-03-18 BR BR9806174-7A patent/BR9806174A/pt not_active Application Discontinuation
- 1998-03-18 PT PT98919155T patent/PT969821E/pt unknown
- 1998-03-18 DE DE69815316T patent/DE69815316T2/de not_active Expired - Lifetime
- 1998-03-18 ID IDW990316A patent/ID21477A/id unknown
- 1998-03-18 AU AU72107/98A patent/AU734248B2/en not_active Expired
- 1998-03-18 WO PCT/EP1998/001773 patent/WO1998042318A1/en not_active Ceased
- 1998-03-18 CA CA002269501A patent/CA2269501C/en not_active Expired - Lifetime
- 1998-03-18 SI SI9830489T patent/SI0969821T1/xx unknown
- 1998-03-18 DK DK98919155T patent/DK0969821T3/da active
- 1998-03-18 EP EP98919155A patent/EP0969821B1/en not_active Expired - Lifetime
- 1998-03-18 NZ NZ335364A patent/NZ335364A/xx not_active IP Right Cessation
- 1998-03-18 HU HU0002056A patent/HU224217B1/hu active IP Right Grant
- 1998-03-18 SK SK544-99A patent/SK284813B6/sk not_active IP Right Cessation
- 1998-03-18 PL PL98335542A patent/PL190566B1/pl unknown
- 1998-03-18 AT AT98919155T patent/ATE241969T1/de active
-
1999
- 1999-04-23 BG BG103356A patent/BG64434B1/bg unknown
- 1999-04-30 NO NO19992114A patent/NO325102B1/no not_active IP Right Cessation
- 1999-09-24 OA OA9900215A patent/OA11162A/en unknown
-
2003
- 2003-11-04 CY CY0300079A patent/CY2384B1/xx unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994005263A1 (en) * | 1992-09-03 | 1994-03-17 | Janssen Pharmaceutica N.V. | Beads having a core coated with an antifungal and a polymer |
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