RU2158266C2 - Способ получения пуриновых соединений, используемое в нем промежуточное соединение и способ его получения - Google Patents

Способ получения пуриновых соединений, используемое в нем промежуточное соединение и способ его получения Download PDF

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Publication number
RU2158266C2
RU2158266C2 RU96121936/04A RU96121936A RU2158266C2 RU 2158266 C2 RU2158266 C2 RU 2158266C2 RU 96121936/04 A RU96121936/04 A RU 96121936/04A RU 96121936 A RU96121936 A RU 96121936A RU 2158266 C2 RU2158266 C2 RU 2158266C2
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RU
Russia
Prior art keywords
formula
compound
amino group
compounds
hydrogen
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RU96121936/04A
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English (en)
Russian (ru)
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RU96121936A (ru
Inventor
Джон Роберт Мэнсфилд Дэйлз
Original Assignee
СмитКлайн Бичем ПЛК
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Application filed by СмитКлайн Бичем ПЛК filed Critical СмитКлайн Бичем ПЛК
Publication of RU96121936A publication Critical patent/RU96121936A/ru
Application granted granted Critical
Publication of RU2158266C2 publication Critical patent/RU2158266C2/ru

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Chemical Treatment Of Metals (AREA)
  • Saccharide Compounds (AREA)
RU96121936/04A 1994-04-19 1995-04-19 Способ получения пуриновых соединений, используемое в нем промежуточное соединение и способ его получения RU2158266C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9407698.1 1994-04-19
GB9407698A GB9407698D0 (en) 1994-04-19 1994-04-19 Pharmaceuticals

Publications (2)

Publication Number Publication Date
RU96121936A RU96121936A (ru) 1999-01-27
RU2158266C2 true RU2158266C2 (ru) 2000-10-27

Family

ID=10753741

Family Applications (1)

Application Number Title Priority Date Filing Date
RU96121936/04A RU2158266C2 (ru) 1994-04-19 1995-04-19 Способ получения пуриновых соединений, используемое в нем промежуточное соединение и способ его получения

Country Status (40)

Country Link
US (2) US6846927B1 (ko)
EP (1) EP0756597B1 (ko)
JP (1) JP3936734B2 (ko)
KR (1) KR100327147B1 (ko)
CN (1) CN1045963C (ko)
AP (2) AP582A (ko)
AT (1) ATE201209T1 (ko)
AU (1) AU691000B2 (ko)
BG (1) BG63464B1 (ko)
BR (1) BR9507494A (ko)
CA (1) CA2188181C (ko)
CZ (1) CZ287674B6 (ko)
DE (1) DE69520945T2 (ko)
DK (1) DK0756597T3 (ko)
DZ (1) DZ1872A1 (ko)
EG (1) EG20938A (ko)
ES (1) ES2158948T3 (ko)
FI (1) FI119691B (ko)
GB (1) GB9407698D0 (ko)
GR (1) GR3036338T3 (ko)
HK (1) HK1012348A1 (ko)
HU (1) HU226209B1 (ko)
IL (1) IL113409A (ko)
IN (1) IN183830B (ko)
MA (1) MA23518A1 (ko)
MX (1) MX9604942A (ko)
MY (1) MY128846A (ko)
NO (1) NO315000B1 (ko)
NZ (1) NZ287858A (ko)
OA (1) OA10376A (ko)
PL (1) PL181219B1 (ko)
PT (1) PT756597E (ko)
RO (1) RO118950B1 (ko)
RU (1) RU2158266C2 (ko)
SA (1) SA95150619B1 (ko)
SK (1) SK283193B6 (ko)
TW (1) TW311138B (ko)
UA (1) UA47401C2 (ko)
WO (1) WO1995028402A2 (ko)
ZA (1) ZA953110B (ko)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9615276D0 (en) * 1996-07-20 1996-09-04 Smithkline Beecham Plc Pharmaceuticals
GB9615253D0 (en) * 1996-07-20 1996-09-04 Smithkline Beecham Plc Pharmaceuticals
GB9807116D0 (en) * 1998-04-02 1998-06-03 Smithkline Beecham Plc Novel process
GB9807114D0 (en) 1998-04-02 1998-06-03 Smithkline Beecham Plc Novel process
WO2004018470A2 (en) * 2002-08-26 2004-03-04 Teva Pharmaceutical Industries Ltd. Crystalline solid famciclovir forms i, ii, iii and preparation thereof
US20040266795A1 (en) * 2003-04-30 2004-12-30 Genny Shamai Process for the preparation of famciclovir
EP1556383A1 (en) * 2003-09-04 2005-07-27 Teva Pharmaceutical Industries Ltd. Process for preparing famciclovir
US7458839B2 (en) * 2006-02-21 2008-12-02 Fci Americas Technology, Inc. Electrical connectors having power contacts with alignment and/or restraining features
US20050215787A1 (en) * 2004-03-26 2005-09-29 Joshi Ramesh A An improved process for the preparation of purines
WO2005116031A1 (en) 2004-05-18 2005-12-08 Teva Pharmaceutical Industries Ltd. Drying process for preparing crystalline solid famciclovir
GB2426247A (en) * 2005-05-20 2006-11-22 Arrow Int Ltd Methods of preparing purine derivatives such as famciclovir
CN102070636B (zh) * 2011-01-17 2012-05-23 浙江大学 喷昔洛韦的制备方法
CN104086552B (zh) * 2014-07-31 2016-01-13 济南兆康医药科技有限公司 一种喷昔洛韦的精制方法
CN104496991A (zh) * 2014-11-04 2015-04-08 常州康丽制药有限公司 高品质2-氨基-6-氯-9-(4-羟基-3–羟甲基丁基)嘌呤的制备方法
CN104744472A (zh) * 2015-03-12 2015-07-01 常州康丽制药有限公司 高品质2-氨基-6-氯-9-(4-羟基-3-羟甲基丁基)嘌呤的制备方法
CN108314685B (zh) * 2018-03-16 2020-08-25 上药康丽（常州）药业有限公司 一种2-氨基-6-氯-9-(4-乙酰氧基-3-乙酰氧甲基丁基)嘌呤的制备方法
CN110713490A (zh) * 2018-07-12 2020-01-21 浙江医药股份有限公司新昌制药厂 一种喷昔洛韦的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3485225D1 (de) * 1983-08-18 1991-12-05 Beecham Group Plc Antivirale guanin-derivate.
DE3582399D1 (de) * 1984-09-20 1991-05-08 Beecham Group Plc Purin-derivate und ihre pharmazeutische verwendung.
ES2098219T3 (es) * 1987-08-01 1997-05-01 Beecham Group Plc Compuestos de purina y su preparacion.
GB8817607D0 (en) * 1988-07-23 1988-09-01 Beecham Group Plc Novel process
GB8822236D0 (en) * 1988-09-21 1988-10-26 Beecham Group Plc Chemical process

Also Published As

Publication number Publication date
NO315000B1 (no) 2003-06-23
GR3036338T3 (en) 2001-11-30
SK283193B6 (sk) 2003-03-04
PL316943A1 (en) 1997-02-17
AP582A (en) 1997-04-09
BG63464B1 (bg) 2002-02-28
AP9600870A0 (en) 1996-10-31
WO1995028402A2 (en) 1995-10-26
RO118950B1 (ro) 2004-01-30
EP0756597A1 (en) 1997-02-05
DE69520945T2 (de) 2002-03-28
CZ305396A3 (en) 1997-06-11
NZ287858A (en) 1998-06-26
FI119691B (fi) 2009-02-13
CA2188181A1 (en) 1995-10-26
BG100926A (en) 1997-07-31
SK133296A3 (en) 1997-05-07
US7355043B2 (en) 2008-04-08
NO964395L (no) 1996-10-15
IN183830B (ko) 2000-04-29
WO1995028402A3 (en) 1996-01-25
HK1012348A1 (en) 1999-07-30
AP703A (en) 1998-12-04
JPH09512000A (ja) 1997-12-02
IL113409A0 (en) 1995-07-31
GB9407698D0 (en) 1994-06-15
CN1045963C (zh) 1999-10-27
JP3936734B2 (ja) 2007-06-27
KR970702280A (ko) 1997-05-13
DZ1872A1 (fr) 2002-02-17
CN1150427A (zh) 1997-05-21
BR9507494A (pt) 1997-08-12
SA95150619B1 (ar) 2005-05-04
MA23518A1 (fr) 1995-12-31
MX9604942A (es) 1998-05-31
CZ287674B6 (en) 2001-01-17
HUT75339A (en) 1997-05-28
KR100327147B1 (ko) 2002-07-27
TW311138B (ko) 1997-07-21
UA47401C2 (uk) 2002-07-15
HU226209B1 (en) 2008-06-30
US6846927B1 (en) 2005-01-25
EG20938A (en) 2000-06-28
ES2158948T3 (es) 2001-09-16
ZA953110B (en) 1996-05-20
AU691000B2 (en) 1998-05-07
PL181219B1 (pl) 2001-06-29
AP9500730A0 (en) 1995-04-30
FI964193A (fi) 1996-12-18
HU9602891D0 (en) 1996-12-30
NO964395D0 (no) 1996-10-15
FI964193A0 (fi) 1996-10-18
EP0756597B1 (en) 2001-05-16
OA10376A (en) 2001-11-20
MY128846A (en) 2007-02-28
CA2188181C (en) 2007-04-17
IL113409A (en) 1999-08-17
DK0756597T3 (da) 2001-08-20
ATE201209T1 (de) 2001-06-15
DE69520945D1 (de) 2001-06-21
PT756597E (pt) 2001-11-30
AU2670695A (en) 1995-11-10
US20050101570A1 (en) 2005-05-12

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