RS20060259A - Macrocyclic carboxylic acids and acylsulfonamides as inhibitors of hcv replication - Google Patents
Macrocyclic carboxylic acids and acylsulfonamides as inhibitors of hcv replicationInfo
- Publication number
- RS20060259A RS20060259A YUP-2006/0259A YUP20060259A RS20060259A RS 20060259 A RS20060259 A RS 20060259A YU P20060259 A YUP20060259 A YU P20060259A RS 20060259 A RS20060259 A RS 20060259A
- Authority
- RS
- Serbia
- Prior art keywords
- acylsulfonamides
- inhibitors
- methods
- carboxylic acids
- hcv replication
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
Abstract
Prikazani pronalazak obezbeđuje jedinjenja opštih formula I-IX kao i kompozicije, uključujući farmaceutske kompozicije, koje sadrže ova jedinjenja. Prikazani pronalazak dalje obebeđuje postupke lečenja, uključujući postupke lečenja infekcije virusa hepatitisa C i postupaka lečenja fibroze jetre, postupci generalno uključuju davanje pojedincima kojima je potrebno efikasne količine ovih jedinjenja ili kompozicija.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US51154103P | 2003-10-14 | 2003-10-14 | |
US61246004P | 2004-09-22 | 2004-09-22 | |
PCT/US2004/033970 WO2005037214A2 (en) | 2003-10-14 | 2004-10-13 | Macrocyclic carboxylic acids and acylsulfonamides as inhibitors of hcv replication |
Publications (1)
Publication Number | Publication Date |
---|---|
RS20060259A true RS20060259A (en) | 2008-08-07 |
Family
ID=34467992
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RS20060259A RS54573B1 (sr) | 2003-10-14 | 2004-10-13 | Makrociklične karboksilne kiseline i acilsulfonamidi kao inhibitori replikacije hcv |
RS20110578A RS20110578A3 (sr) | 2003-10-14 | 2004-10-13 | Makrociklične karboksilne kiseline i acilsulfonamidi kao inhibitori replikacije hcv |
YUP-2006/0259A RS20060259A (en) | 2003-10-14 | 2004-10-13 | Macrocyclic carboxylic acids and acylsulfonamides as inhibitors of hcv replication |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RS20060259A RS54573B1 (sr) | 2003-10-14 | 2004-10-13 | Makrociklične karboksilne kiseline i acilsulfonamidi kao inhibitori replikacije hcv |
RS20110578A RS20110578A3 (sr) | 2003-10-14 | 2004-10-13 | Makrociklične karboksilne kiseline i acilsulfonamidi kao inhibitori replikacije hcv |
Country Status (30)
Country | Link |
---|---|
EP (2) | EP2407470A3 (sr) |
JP (3) | JP4584260B2 (sr) |
KR (1) | KR100853579B1 (sr) |
CN (2) | CN102020697B (sr) |
AP (2) | AP2287A (sr) |
AR (2) | AR046422A1 (sr) |
AU (1) | AU2004281780B2 (sr) |
BR (1) | BRPI0415373A (sr) |
CA (1) | CA2540858C (sr) |
CY (1) | CY1113809T1 (sr) |
DK (1) | DK1680137T3 (sr) |
EA (1) | EA011857B8 (sr) |
EC (2) | ECSP066570A (sr) |
ES (1) | ES2398912T3 (sr) |
GE (1) | GEP20084560B (sr) |
HK (2) | HK1100164A1 (sr) |
HR (1) | HRP20130098T1 (sr) |
IL (3) | IL174704A (sr) |
IS (1) | IS2876B (sr) |
MA (1) | MA28152A1 (sr) |
MX (1) | MXPA06003963A (sr) |
MY (1) | MY144593A (sr) |
NO (1) | NO343231B1 (sr) |
NZ (1) | NZ546347A (sr) |
OA (1) | OA13315A (sr) |
PL (1) | PL1680137T3 (sr) |
PT (1) | PT1680137E (sr) |
RS (3) | RS54573B1 (sr) |
TW (2) | TWI375679B (sr) |
WO (1) | WO2005037214A2 (sr) |
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