SG11201507467VA - Sovaprevir polymorphs and methods of manufacture thereof - Google Patents
Sovaprevir polymorphs and methods of manufacture thereofInfo
- Publication number
- SG11201507467VA SG11201507467VA SG11201507467VA SG11201507467VA SG11201507467VA SG 11201507467V A SG11201507467V A SG 11201507467VA SG 11201507467V A SG11201507467V A SG 11201507467VA SG 11201507467V A SG11201507467V A SG 11201507467VA SG 11201507467V A SG11201507467V A SG 11201507467VA
- Authority
- SG
- Singapore
- Prior art keywords
- sovaprevir
- polymorphs
- manufacture
- methods
- sovaprevir polymorphs
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361786927P | 2013-03-15 | 2013-03-15 | |
PCT/US2014/028348 WO2014144087A1 (en) | 2013-03-15 | 2014-03-14 | Sovaprevir polymorphs and methods of manufacture thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201507467VA true SG11201507467VA (en) | 2015-10-29 |
Family
ID=50483591
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201507467VA SG11201507467VA (en) | 2013-03-15 | 2014-03-14 | Sovaprevir polymorphs and methods of manufacture thereof |
Country Status (11)
Country | Link |
---|---|
US (2) | US9227952B2 (en) |
EP (1) | EP2970192A1 (en) |
JP (1) | JP2016513732A (en) |
KR (1) | KR20160005686A (en) |
AU (1) | AU2014227849A1 (en) |
BR (1) | BR112015023351A2 (en) |
IL (1) | IL241290A0 (en) |
MX (1) | MX2015013020A (en) |
PH (1) | PH12015502122A1 (en) |
SG (1) | SG11201507467VA (en) |
WO (1) | WO2014144087A1 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2448494T3 (en) | 2006-07-13 | 2014-03-14 | Achillion Pharmaceuticals, Inc. | 4-amino-4-oxobutanoyl peptides as viral replication inhibitors |
GB201112231D0 (en) | 2011-07-15 | 2011-08-31 | Verdant Bioproducts Ltd | Micro-organism |
CN109641874A (en) | 2016-05-10 | 2019-04-16 | C4医药公司 | C for target protein degradation3The glutarimide degron body of carbon connection |
WO2017197055A1 (en) | 2016-05-10 | 2017-11-16 | C4 Therapeutics, Inc. | Heterocyclic degronimers for target protein degradation |
EP3454862A4 (en) | 2016-05-10 | 2020-02-12 | C4 Therapeutics, Inc. | Spirocyclic degronimers for target protein degradation |
Family Cites Families (58)
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WO1991001327A1 (en) | 1989-07-19 | 1991-02-07 | The Upjohn Company | Peptides containing diamino-glycols as transition-state mimics |
JP2668003B2 (en) | 1992-06-12 | 1997-10-27 | ファイザー インク. | Inhibitors for angiotensin I chymase, including human heart chymase |
US6608027B1 (en) | 1999-04-06 | 2003-08-19 | Boehringer Ingelheim (Canada) Ltd | Macrocyclic peptides active against the hepatitis C virus |
AU2002248147B2 (en) | 2000-11-20 | 2006-04-06 | Bristol-Myers Squibb Company | Hepatitis C tripeptide inhibitors |
US6867185B2 (en) | 2001-12-20 | 2005-03-15 | Bristol-Myers Squibb Company | Inhibitors of hepatitis C virus |
US7119072B2 (en) | 2002-01-30 | 2006-10-10 | Boehringer Ingelheim (Canada) Ltd. | Macrocyclic peptides active against the hepatitis C virus |
DE60334205D1 (en) | 2002-05-20 | 2010-10-28 | Bristol Myers Squibb Co | Heterocyclische sulfonamid-hepatitis-c-virus-hemmer |
ES2361011T3 (en) | 2002-05-20 | 2011-06-13 | Bristol-Myers Squibb Company | HEPATITIS VIRUS INHIBITORS C. |
PL213029B1 (en) | 2002-05-20 | 2012-12-31 | Bristol Myers Squibb Co | Substituted cycloalkyl p1' hepatitis c virus inhibitors |
US20060199773A1 (en) | 2002-05-20 | 2006-09-07 | Sausker Justin B | Crystalline forms of (1R,2S)-N-[(1,1-dimethylethoxy)carbonyl]-3-methyl-L-valyl-(4R)-4-[(6-methoxy-1-isoquinolinyl)oxy]-L-prolyl-1-amino-N-(cyclopropylsulfonyl)-2-ethenyl-cyclopropanecarboxamide, monopotassium salt |
MY140680A (en) | 2002-05-20 | 2010-01-15 | Bristol Myers Squibb Co | Hepatitis c virus inhibitors |
KR100840715B1 (en) | 2002-05-28 | 2008-06-23 | 삼성전자주식회사 | Back light assembly and liquid crystal display having the same |
EP1408031A1 (en) | 2002-10-09 | 2004-04-14 | 3 D Gene Pharma | Pyrolidine derivatives useful in treatment of hepatitis C virus infection |
US7601709B2 (en) | 2003-02-07 | 2009-10-13 | Enanta Pharmaceuticals, Inc. | Macrocyclic hepatitis C serine protease inhibitors |
CA2515216A1 (en) | 2003-02-07 | 2004-08-26 | Enanta Pharmaceuticals, Inc. | Macrocyclic hepatitis c serine protease inhibitors |
ATE486889T1 (en) | 2003-03-05 | 2010-11-15 | Boehringer Ingelheim Int | PEPTIDE ANALOGUES WITH INHIBITORY EFFECT ON HEPATITIS C |
ES2320771T3 (en) | 2003-04-16 | 2009-05-28 | Bristol-Myers Squibb Company | PEPTIDIC INHIBITORS OF MACROCICLIC ISOQUINOLINE VIRUS OF HEPATITIS C. |
US7176208B2 (en) | 2003-04-18 | 2007-02-13 | Enanta Pharmaceuticals, Inc. | Quinoxalinyl macrocyclic hepatitis C serine protease inhibitors |
JP4447603B2 (en) | 2003-05-21 | 2010-04-07 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Hepatitis C inhibitor compound |
WO2004113365A2 (en) | 2003-06-05 | 2004-12-29 | Enanta Pharmaceuticals, Inc. | Hepatitis c serine protease tri-peptide inhibitors |
PE20050251A1 (en) | 2003-07-18 | 2005-04-13 | Vertex Pharma | SERINE PROTEASE INHIBITORS, ESPECIALLY HCV PROTEASE NS3-NS4A |
UY28525A1 (en) | 2003-09-22 | 2005-04-29 | Boehringer Ingelheim Int | ACTIVE MACROCICLIC PEPTIDES AGAINST HEPATITIS C VIRUSES |
CA2540858C (en) | 2003-10-14 | 2009-12-08 | Intermune, Inc. | Macrocyclic carboxylic acids and acylsulfonamides as inhibitors of hcv replication |
US7491794B2 (en) | 2003-10-14 | 2009-02-17 | Intermune, Inc. | Macrocyclic compounds as inhibitors of viral replication |
US7132504B2 (en) | 2003-11-12 | 2006-11-07 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
US7309708B2 (en) | 2003-11-20 | 2007-12-18 | Birstol-Myers Squibb Company | Hepatitis C virus inhibitors |
US7135462B2 (en) | 2003-11-20 | 2006-11-14 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
EP1730167B1 (en) | 2004-01-21 | 2011-01-12 | Boehringer Ingelheim International GmbH | Macrocyclic peptides active against the hepatitis c virus |
ES2336009T3 (en) | 2004-01-30 | 2010-04-07 | Medivir Ab | INHIBITORS OF THE NS-3 SERINA PROTEASA HCV. |
AU2005224092A1 (en) | 2004-03-15 | 2005-09-29 | Boehringer Ingelheim International, Gmbh | Process for preparing macrocyclic dipeptides which are suitable for the treatment of hepatitis C viral infections |
EA012389B1 (en) | 2004-03-30 | 2009-10-30 | Интермун, Инк. | Macrocyclic compounds as inhibitors of viral replication |
AU2005274700B2 (en) | 2004-07-16 | 2011-11-10 | Gilead Sciences, Inc. | Antiviral compounds |
UY29016A1 (en) | 2004-07-20 | 2006-02-24 | Boehringer Ingelheim Int | ANALOGS OF INHIBITING DIPEPTIDES OF HEPATITIS C |
CA2573346C (en) | 2004-07-20 | 2011-09-20 | Boehringer Ingelheim International Gmbh | Hepatitis c inhibitor peptide analogs |
US7153848B2 (en) | 2004-08-09 | 2006-12-26 | Bristol-Myers Squibb Company | Inhibitors of HCV replication |
EP1794178A1 (en) | 2004-09-17 | 2007-06-13 | Boehringer Ingelheim International Gmbh | Process for preparing macrocyclic hcv protease inhibitors |
US7659263B2 (en) | 2004-11-12 | 2010-02-09 | Japan Tobacco Inc. | Thienopyrrole compound and use thereof as HCV polymerase inhibitor |
US7323447B2 (en) | 2005-02-08 | 2008-01-29 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
CA2600367C (en) | 2005-03-08 | 2014-08-12 | Boehringer Ingelheim International Gmbh | Process for preparing macrocyclic compounds |
US7592336B2 (en) | 2005-05-10 | 2009-09-22 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
WO2006130686A2 (en) | 2005-06-02 | 2006-12-07 | Schering Corporation | Hcv protease inhibitors in combination with food |
US7608592B2 (en) | 2005-06-30 | 2009-10-27 | Virobay, Inc. | HCV inhibitors |
US7601686B2 (en) | 2005-07-11 | 2009-10-13 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
TWI389908B (en) | 2005-07-14 | 2013-03-21 | Gilead Sciences Inc | Antiviral compounds |
JP2009501732A (en) | 2005-07-20 | 2009-01-22 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Hepatitis C inhibitor peptide analog |
EA019888B1 (en) | 2005-07-25 | 2014-07-30 | Интермьюн, Инк. | Intermediate compound for making macrocyclic inhibitors of hepatitis c virus replication and method of synthesis thereof |
JO2768B1 (en) | 2005-07-29 | 2014-03-15 | تيبوتيك فارماسيوتيكالز ليمتد | Macrocylic Inhibitors Hepatitis C Virus |
EP1934243B1 (en) | 2005-09-09 | 2011-05-25 | Boehringer Ingelheim International GmbH | Ring-closing metathesis process for the preparation of macrocyclic peptides |
DK1999129T3 (en) | 2005-10-11 | 2011-02-07 | Intermune Inc | Compounds and Methods for Inhibiting the Replication of Hepatitis C Virus |
US7772183B2 (en) | 2005-10-12 | 2010-08-10 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
US7741281B2 (en) | 2005-11-03 | 2010-06-22 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
ES2448494T3 (en) | 2006-07-13 | 2014-03-14 | Achillion Pharmaceuticals, Inc. | 4-amino-4-oxobutanoyl peptides as viral replication inhibitors |
EP1881002A1 (en) | 2006-07-20 | 2008-01-23 | Tibotec Pharmaceuticals Ltd. | HCV NS-3 serine protease inhibitors |
EA200900969A1 (en) | 2007-01-08 | 2010-02-26 | Феномикс Корпорейшн | MACROCYCLIC INHIBITORS OF HEPATITIS C PROTEASE |
WO2008095058A1 (en) | 2007-02-01 | 2008-08-07 | Taigen Biotechnology Co. Ltd. | Hcv protease inhibitors |
BRPI0922912A8 (en) | 2008-12-10 | 2018-01-02 | Achillion Pharmaceuticals Inc | 4-amino-4-oxobutanoyl peptides as viral replication inhibitors |
TW201329025A (en) * | 2011-11-01 | 2013-07-16 | Astex Therapeutics Ltd | Pharmaceutical compounds |
JP2016512845A (en) | 2013-03-15 | 2016-05-09 | アキリオン ファーマシューティカルズ,インコーポレーテッド | Sobaprevir tablets |
-
2014
- 2014-03-14 MX MX2015013020A patent/MX2015013020A/en unknown
- 2014-03-14 WO PCT/US2014/028348 patent/WO2014144087A1/en active Application Filing
- 2014-03-14 AU AU2014227849A patent/AU2014227849A1/en not_active Abandoned
- 2014-03-14 KR KR1020157029000A patent/KR20160005686A/en not_active Application Discontinuation
- 2014-03-14 EP EP14717363.7A patent/EP2970192A1/en not_active Withdrawn
- 2014-03-14 SG SG11201507467VA patent/SG11201507467VA/en unknown
- 2014-03-14 BR BR112015023351A patent/BR112015023351A2/en not_active IP Right Cessation
- 2014-03-14 JP JP2016502765A patent/JP2016513732A/en active Pending
- 2014-03-14 US US14/211,948 patent/US9227952B2/en not_active Expired - Fee Related
-
2015
- 2015-09-07 IL IL241290A patent/IL241290A0/en unknown
- 2015-09-14 PH PH12015502122A patent/PH12015502122A1/en unknown
- 2015-11-25 US US14/951,703 patent/US9540346B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
WO2014144087A1 (en) | 2014-09-18 |
IL241290A0 (en) | 2015-11-30 |
KR20160005686A (en) | 2016-01-15 |
JP2016513732A (en) | 2016-05-16 |
EP2970192A1 (en) | 2016-01-20 |
US9227952B2 (en) | 2016-01-05 |
AU2014227849A1 (en) | 2015-10-01 |
MX2015013020A (en) | 2016-06-10 |
BR112015023351A2 (en) | 2017-07-18 |
US9540346B2 (en) | 2017-01-10 |
US20160176847A1 (en) | 2016-06-23 |
US20140275163A1 (en) | 2014-09-18 |
PH12015502122A1 (en) | 2016-01-25 |
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