NO20062089L - Makrosykliske karboksylsyrer og acylsulfonamider som inhibitorer av HCV-replikasjon - Google Patents
Makrosykliske karboksylsyrer og acylsulfonamider som inhibitorer av HCV-replikasjonInfo
- Publication number
- NO20062089L NO20062089L NO20062089A NO20062089A NO20062089L NO 20062089 L NO20062089 L NO 20062089L NO 20062089 A NO20062089 A NO 20062089A NO 20062089 A NO20062089 A NO 20062089A NO 20062089 L NO20062089 L NO 20062089L
- Authority
- NO
- Norway
- Prior art keywords
- acylsulfonamides
- inhibitors
- carboxylic acids
- hcv replication
- methods
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Foreliggende oppfinnelse tilveiebringer forbindelser med de generelle formlene I-IX, så vel som forbindelser som inkluderer farmasøytiske sammensetninger, omfattende en emneforbindelse. Foreliggende oppfinnelse tilveiebringer også behandlingsfremgangsmåter inkludert fremgangsmåter for behandling av hepatitt C virusinfeksjon og fremgangsmåter for behandling av leverfibrose, der fremgangsmåtene generelt involverer tilførsel til et individ med sådant behov av en effektiv mengde av en subjektforbindelse eller en emnesammensetning.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US51154103P | 2003-10-14 | 2003-10-14 | |
US61246004P | 2004-09-22 | 2004-09-22 | |
PCT/US2004/033970 WO2005037214A2 (en) | 2003-10-14 | 2004-10-13 | Macrocyclic carboxylic acids and acylsulfonamides as inhibitors of hcv replication |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20062089L true NO20062089L (no) | 2006-05-09 |
NO343231B1 NO343231B1 (no) | 2018-12-10 |
Family
ID=34467992
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20062089A NO343231B1 (no) | 2003-10-14 | 2006-05-09 | Forbindelse og farmasøytisk sammensetning omfattende nevnte forbindelse og anvendelse derav i behandling av HCV-infeksjon. |
Country Status (30)
Country | Link |
---|---|
EP (2) | EP1680137B1 (no) |
JP (3) | JP4584260B2 (no) |
KR (1) | KR100853579B1 (no) |
CN (2) | CN102020697B (no) |
AP (2) | AP2287A (no) |
AR (2) | AR046422A1 (no) |
AU (1) | AU2004281780B2 (no) |
BR (1) | BRPI0415373A (no) |
CA (1) | CA2540858C (no) |
CY (1) | CY1113809T1 (no) |
DK (1) | DK1680137T3 (no) |
EA (1) | EA011857B8 (no) |
EC (2) | ECSP066570A (no) |
ES (1) | ES2398912T3 (no) |
GE (1) | GEP20084560B (no) |
HK (2) | HK1100164A1 (no) |
HR (1) | HRP20130098T1 (no) |
IL (3) | IL174704A (no) |
IS (1) | IS2876B (no) |
MA (1) | MA28152A1 (no) |
MX (1) | MXPA06003963A (no) |
MY (1) | MY144593A (no) |
NO (1) | NO343231B1 (no) |
NZ (1) | NZ546347A (no) |
OA (1) | OA13315A (no) |
PL (1) | PL1680137T3 (no) |
PT (1) | PT1680137E (no) |
RS (3) | RS20110578A3 (no) |
TW (2) | TW201245229A (no) |
WO (1) | WO2005037214A2 (no) |
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Free format text: KORREKT PCT NR. ER PCT/US2004/033970. |