PT1689233E - Inibidores bicíclicos de mek - Google Patents

Inibidores bicíclicos de mek Download PDF

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Publication number
PT1689233E
PT1689233E PT04811728T PT04811728T PT1689233E PT 1689233 E PT1689233 E PT 1689233E PT 04811728 T PT04811728 T PT 04811728T PT 04811728 T PT04811728 T PT 04811728T PT 1689233 E PT1689233 E PT 1689233E
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PT
Portugal
Prior art keywords
heteroaryl
aryl
alkyl
cycloalkyl
trifluoromethyl
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PT04811728T
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English (en)
Portuguese (pt)
Inventor
Eli Wallace
Hong Woon Yang
Jim Blake
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Array Biopharma Inc
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Publication of PT1689233E publication Critical patent/PT1689233E/pt

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    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
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    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
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    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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