PL209954B1 - Sposób oczyszczania białek interferonu i jego zastosowanie - Google Patents

Sposób oczyszczania białek interferonu i jego zastosowanie

Info

Publication number
PL209954B1
PL209954B1 PL354769A PL35476902A PL209954B1 PL 209954 B1 PL209954 B1 PL 209954B1 PL 354769 A PL354769 A PL 354769A PL 35476902 A PL35476902 A PL 35476902A PL 209954 B1 PL209954 B1 PL 209954B1
Authority
PL
Poland
Prior art keywords
proteins
purification
interferon
protein
sodium
Prior art date
Application number
PL354769A
Other languages
English (en)
Polish (pl)
Other versions
PL354769A1 (en
Inventor
Lucia Scapol
Giuseppe Claudio Viscomi
Original Assignee
Alfa Wassermann Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alfa Wassermann Spa filed Critical Alfa Wassermann Spa
Publication of PL354769A1 publication Critical patent/PL354769A1/xx
Publication of PL209954B1 publication Critical patent/PL209954B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/811—Interferon

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL354769A 2001-07-06 2002-06-27 Sposób oczyszczania białek interferonu i jego zastosowanie PL209954B1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2001BO000426A ITBO20010426A1 (it) 2001-07-06 2001-07-06 Processo per la purificazione di proteine farmacologicamente attive mediante cromatografia in scambio cationico

Publications (2)

Publication Number Publication Date
PL354769A1 PL354769A1 (en) 2003-01-13
PL209954B1 true PL209954B1 (pl) 2011-11-30

Family

ID=11439471

Family Applications (1)

Application Number Title Priority Date Filing Date
PL354769A PL209954B1 (pl) 2001-07-06 2002-06-27 Sposób oczyszczania białek interferonu i jego zastosowanie

Country Status (27)

Country Link
US (1) US6866782B2 (en:Method)
EP (1) EP1273592B1 (en:Method)
JP (1) JP3940037B2 (en:Method)
KR (1) KR100771252B1 (en:Method)
CN (1) CN100484954C (en:Method)
AR (1) AR034663A1 (en:Method)
AT (1) ATE307824T1 (en:Method)
BG (1) BG65748B1 (en:Method)
BR (1) BR0202431A (en:Method)
CA (1) CA2388716C (en:Method)
CU (1) CU23149A3 (en:Method)
DE (1) DE60206847T2 (en:Method)
DK (1) DK1273592T3 (en:Method)
DZ (1) DZ3236A1 (en:Method)
EG (1) EG23150A (en:Method)
ES (1) ES2250544T3 (en:Method)
HR (1) HRP20020480B1 (en:Method)
HU (1) HUP0202124A2 (en:Method)
IT (1) ITBO20010426A1 (en:Method)
ME (1) MEP3408A (en:Method)
MX (1) MXPA02006303A (en:Method)
PL (1) PL209954B1 (en:Method)
RS (1) RS51512B (en:Method)
RU (1) RU2274471C2 (en:Method)
SI (1) SI1273592T1 (en:Method)
SK (1) SK287827B6 (en:Method)
UY (1) UY27354A1 (en:Method)

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JP2007500852A (ja) * 2003-05-16 2007-01-18 クリオバイオフィジカ， インコーポレイテッド 外部勾配クロマトフォーカシング
JP3920913B2 (ja) * 2004-03-30 2007-05-30 寛 柳澤 タンパク質の分離方法
US7449116B2 (en) * 2004-10-01 2008-11-11 Agilent Technologies, Inc. Methods and systems for protein separation
US7943046B2 (en) * 2004-10-01 2011-05-17 Agilent Technologies, Inc Methods and systems for on-column protein delipidation
ES2532804T3 (es) * 2006-04-12 2015-03-31 Crealta Pharmaceuticals Llc Purificación de proteínas con tensioactivo catiónico
WO2009073975A1 (en) * 2007-12-10 2009-06-18 National Research Council Of Canada Production of recombinant interferon proteins
DE102009032179A1 (de) 2009-07-07 2011-01-13 Biogenerix Ag Verfahren zur Reinigung von Interferon beta
CN101768601B (zh) * 2010-02-01 2013-08-07 山东泉港药业有限公司 一种重组人血白蛋白—干扰素α2b的生产方法
SG10201605397PA (en) * 2011-07-01 2016-08-30 Hoffmann La Roche Method For Separation Of Monomeric Polypeptides From Aggregated Polypeptides
US8921113B2 (en) 2012-12-21 2014-12-30 Dionex Corporation Buffer kit and method of generating a linear pH gradient
US9650412B2 (en) * 2013-03-08 2017-05-16 Genzyme Corporation Integrated continuous manufacturing of therapeutic protein drug substances
CN104236983A (zh) * 2013-06-14 2014-12-24 中国科学院大连化学物理研究所 溶液样品中含长烷基链的离子液体的去除方法
TWI709569B (zh) 2014-01-17 2020-11-11 美商健臻公司 無菌層析樹脂及其用於製造方法的用途
TWI671312B (zh) 2014-01-17 2019-09-11 美商健臻公司 無菌層析法及製法
WO2016079598A1 (en) * 2014-11-18 2016-05-26 Unichem Laboratories Limited An improved process for the preparation of pharmacopoeial grade interferon alpha 2b
CN106496302B (zh) * 2015-09-08 2021-12-10 三生国健药业（上海）股份有限公司 一种用离子交换层析纯化蛋白质的方法
GB201517450D0 (en) * 2015-10-02 2015-11-18 Ipsen Biopharm Ltd Method
JP2018536418A (ja) * 2015-12-09 2018-12-13 ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ 脱離条件下で発酵固体からタンパク質を精製する方法
GB2568936B (en) 2017-12-01 2019-12-25 Ford Global Tech Llc Liquid cooled injector
BR112021003420A2 (pt) 2018-08-31 2021-05-18 Genzyme Corporation resina cromatográfica estéril e uso da mesma em processos de manufatura
US11022585B2 (en) 2019-06-09 2021-06-01 Dionex Corporation Methods and systems for optimizing buffer conditions with liquid chromatography
CN111138523A (zh) * 2019-12-10 2020-05-12 天津生机集团股份有限公司 一种从重组鸡干扰素α复性液中纯化制备重组鸡干扰素α的方法
CN113968900B (zh) * 2020-07-23 2023-07-25 中元汇吉生物技术股份有限公司 一种纯化C1q蛋白的方法
CN115918902A (zh) * 2022-12-19 2023-04-07 新疆农业科学院农业质量标准与检测技术研究所 一种通过微水波扩散重力法预处理葡萄脱水并获取高酚葡萄提取物的方法

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DE1617401A1 (de) * 1966-05-02 1972-02-17 Centre Nat Rech Scient Verfahren zur Herstellung von Interferon-Praeparaten
US4228154A (en) * 1979-02-26 1980-10-14 Armour Pharmaceutical Company Purification of plasma albumin by ion exchange chromatography
US4534906A (en) * 1982-11-01 1985-08-13 Genentech, Inc. Removal of impurities from human leukocyte interferon preparations
DE3515336C2 (de) * 1985-04-27 1994-01-20 Boehringer Ingelheim Int Verfahren zur Herstellung und Reinigung von â-Interferon
US5196323A (en) * 1985-04-27 1993-03-23 Boehringer Ingelheim International Gmbh Process for preparing and purifying alpha-interferon
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US5521287A (en) * 1992-05-20 1996-05-28 The Green Cross Corporation Recombinant human serum albumin, process for producing the same and pharmaceutical preparation containing the same
US5440018A (en) * 1992-05-20 1995-08-08 The Green Cross Corporation Recombinant human serum albumin, process for producing the same and pharmaceutical preparation containing the same
US5728553A (en) * 1992-09-23 1998-03-17 Delta Biotechnology Limited High purity albumin and method of producing
US5367054A (en) * 1993-04-12 1994-11-22 Stolle Research & Development Corp. Large-scale purification of egg immunoglobulin
ES2161793T3 (es) * 1994-04-09 2001-12-16 Hoffmann La Roche Proceso para la produccion de alfa-interferona.
JP3702474B2 (ja) * 1994-06-01 2005-10-05 三菱ウェルファーマ株式会社 血清アルブミン製剤の製造方法
RU2081122C1 (ru) * 1994-06-16 1997-06-10 Институт биоорганической химии им.М.М.Шемякина и Ю.А.Овчинникова РАН Способ выделения и очистки инсулина или его биотехнологических предшественников
US5486470A (en) * 1994-07-21 1996-01-23 Merck & Co., Inc. Purified herpes simplex virus protease and methods of purification
CA2157219C (en) 1994-08-31 2010-10-05 Munehiro Noda Process for purifying recombinant human serum albumin
EP1736483A3 (en) * 1995-09-07 2008-07-30 Pharming Intellectual Property BV Purification of alpha-1 proteinase inhibitor
RU2132386C1 (ru) * 1997-06-20 1999-06-27 Государственный научный центр вирусологии и биотехнологии "Вектор" Способ получения рекомбинантного интерферона-гамма человека
GB9902000D0 (en) * 1999-01-30 1999-03-17 Delta Biotechnology Ltd Process

Also Published As

Publication number Publication date
ES2250544T3 (es) 2006-04-16
JP3940037B2 (ja) 2007-07-04
CN1396176A (zh) 2003-02-12
HRP20020480B1 (en) 2006-11-30
AR034663A1 (es) 2004-03-03
RS51512B (sr) 2011-06-30
EG23150A (en) 2004-05-31
BG65748B1 (bg) 2009-09-30
EP1273592B1 (en) 2005-10-26
SK8592002A3 (en) 2003-01-09
BR0202431A (pt) 2003-09-09
HUP0202124A2 (hu) 2003-10-28
US6866782B2 (en) 2005-03-15
RU2002117383A (ru) 2004-01-27
MXPA02006303A (es) 2003-02-10
SK287827B6 (sk) 2011-11-04
KR100771252B1 (ko) 2007-10-30
YU50502A (sh) 2005-09-19
CN100484954C (zh) 2009-05-06
UY27354A1 (es) 2003-04-30
MEP3408A (en) 2010-10-10
EP1273592A2 (en) 2003-01-08
JP2003096092A (ja) 2003-04-03
BG106768A (en) 2003-05-30
SI1273592T1 (sl) 2006-02-28
RU2274471C2 (ru) 2006-04-20
US20030010715A1 (en) 2003-01-16
CA2388716C (en) 2008-01-08
DE60206847D1 (de) 2005-12-01
ATE307824T1 (de) 2005-11-15
EP1273592A3 (en) 2003-03-19
CU23149A3 (es) 2006-06-29
DZ3236A1 (fr) 2005-04-20
KR20030005005A (ko) 2003-01-15
DE60206847T2 (de) 2006-07-06
DK1273592T3 (da) 2006-01-02
CA2388716A1 (en) 2003-01-06
ITBO20010426A1 (it) 2003-01-06
ITBO20010426A0 (it) 2001-07-06
HU0202124D0 (en:Method) 2002-09-28
PL354769A1 (en) 2003-01-13
HRP20020480A2 (en) 2003-02-28

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