AR034663A1 - Proceso para la purificacion de proteinas farmacologicamente activas mediante cromatografia de intercambio cationico - Google Patents

Proceso para la purificacion de proteinas farmacologicamente activas mediante cromatografia de intercambio cationico

Info

Publication number
AR034663A1
AR034663A1 ARP020102459A ARP020102459A AR034663A1 AR 034663 A1 AR034663 A1 AR 034663A1 AR P020102459 A ARP020102459 A AR P020102459A AR P020102459 A ARP020102459 A AR P020102459A AR 034663 A1 AR034663 A1 AR 034663A1
Authority
AR
Argentina
Prior art keywords
purification
pharmacologically active
cation exchange
exchange chromatography
proteins
Prior art date
Application number
ARP020102459A
Other languages
English (en)
Spanish (es)
Original Assignee
Alfa Wassermann Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alfa Wassermann Spa filed Critical Alfa Wassermann Spa
Publication of AR034663A1 publication Critical patent/AR034663A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/811—Interferon

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ARP020102459A 2001-07-06 2002-06-28 Proceso para la purificacion de proteinas farmacologicamente activas mediante cromatografia de intercambio cationico AR034663A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2001BO000426A ITBO20010426A1 (it) 2001-07-06 2001-07-06 Processo per la purificazione di proteine farmacologicamente attive mediante cromatografia in scambio cationico

Publications (1)

Publication Number Publication Date
AR034663A1 true AR034663A1 (es) 2004-03-03

Family

ID=11439471

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP020102459A AR034663A1 (es) 2001-07-06 2002-06-28 Proceso para la purificacion de proteinas farmacologicamente activas mediante cromatografia de intercambio cationico

Country Status (27)

Country Link
US (1) US6866782B2 (en:Method)
EP (1) EP1273592B1 (en:Method)
JP (1) JP3940037B2 (en:Method)
KR (1) KR100771252B1 (en:Method)
CN (1) CN100484954C (en:Method)
AR (1) AR034663A1 (en:Method)
AT (1) ATE307824T1 (en:Method)
BG (1) BG65748B1 (en:Method)
BR (1) BR0202431A (en:Method)
CA (1) CA2388716C (en:Method)
CU (1) CU23149A3 (en:Method)
DE (1) DE60206847T2 (en:Method)
DK (1) DK1273592T3 (en:Method)
DZ (1) DZ3236A1 (en:Method)
EG (1) EG23150A (en:Method)
ES (1) ES2250544T3 (en:Method)
HR (1) HRP20020480B1 (en:Method)
HU (1) HUP0202124A2 (en:Method)
IT (1) ITBO20010426A1 (en:Method)
ME (1) MEP3408A (en:Method)
MX (1) MXPA02006303A (en:Method)
PL (1) PL209954B1 (en:Method)
RS (1) RS51512B (en:Method)
RU (1) RU2274471C2 (en:Method)
SI (1) SI1273592T1 (en:Method)
SK (1) SK287827B6 (en:Method)
UY (1) UY27354A1 (en:Method)

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EP1739089A4 (en) * 2004-03-30 2007-05-02 Hiroshi Yanagisawa PROCESS FOR DISINTER SEPARATION
US7943046B2 (en) * 2004-10-01 2011-05-17 Agilent Technologies, Inc Methods and systems for on-column protein delipidation
US7449116B2 (en) * 2004-10-01 2008-11-11 Agilent Technologies, Inc. Methods and systems for protein separation
JP5033177B2 (ja) * 2006-04-12 2012-09-26 サビエント ファーマセウティカルズ インク． 陽イオン界面活性剤によるタンパク質の精製
CA2708291A1 (en) * 2007-12-10 2009-06-18 National Research Council Of Canada Production of recombinant interferon proteins
DE102009032179A1 (de) 2009-07-07 2011-01-13 Biogenerix Ag Verfahren zur Reinigung von Interferon beta
CN101768601B (zh) * 2010-02-01 2013-08-07 山东泉港药业有限公司 一种重组人血白蛋白—干扰素α2b的生产方法
JP6292718B2 (ja) * 2011-07-01 2018-03-14 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 凝集ポリペプチドから単量体ポリペプチドを分離するための方法
US8921113B2 (en) 2012-12-21 2014-12-30 Dionex Corporation Buffer kit and method of generating a linear pH gradient
CN105377874A (zh) * 2013-03-08 2016-03-02 建新公司 治疗性蛋白药物物质的整合连续制造
CN104236983A (zh) * 2013-06-14 2014-12-24 中国科学院大连化学物理研究所 溶液样品中含长烷基链的离子液体的去除方法
TWI709569B (zh) 2014-01-17 2020-11-11 美商健臻公司 無菌層析樹脂及其用於製造方法的用途
TWI671312B (zh) 2014-01-17 2019-09-11 美商健臻公司 無菌層析法及製法
EP3221450A1 (en) * 2014-11-18 2017-09-27 Unichem Laboratories Limited An improved process for the preparation of pharmacopoeial grade interferon alpha 2b
CN106496302B (zh) * 2015-09-08 2021-12-10 三生国健药业（上海）股份有限公司 一种用离子交换层析纯化蛋白质的方法
GB201517450D0 (en) * 2015-10-02 2015-11-18 Ipsen Biopharm Ltd Method
KR20180085737A (ko) * 2015-12-09 2018-07-27 바스프 에스이 탈착 조건 하에서 발효 고형분으로부터 단백질을 정제하는 방법
GB2568936B (en) 2017-12-01 2019-12-25 Ford Global Tech Llc Liquid cooled injector
KR102824467B1 (ko) 2018-08-31 2025-06-26 젠자임 코포레이션 멸균 크로마토그래피 수지 및 제조 공정에서 이의 용도
US11022585B2 (en) 2019-06-09 2021-06-01 Dionex Corporation Methods and systems for optimizing buffer conditions with liquid chromatography
CN111138523A (zh) * 2019-12-10 2020-05-12 天津生机集团股份有限公司 一种从重组鸡干扰素α复性液中纯化制备重组鸡干扰素α的方法
CN113968900B (zh) * 2020-07-23 2023-07-25 中元汇吉生物技术股份有限公司 一种纯化C1q蛋白的方法
CN115918902A (zh) * 2022-12-19 2023-04-07 新疆农业科学院农业质量标准与检测技术研究所 一种通过微水波扩散重力法预处理葡萄脱水并获取高酚葡萄提取物的方法

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US4228154A (en) * 1979-02-26 1980-10-14 Armour Pharmaceutical Company Purification of plasma albumin by ion exchange chromatography
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US5196323A (en) * 1985-04-27 1993-03-23 Boehringer Ingelheim International Gmbh Process for preparing and purifying alpha-interferon
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US5521287A (en) * 1992-05-20 1996-05-28 The Green Cross Corporation Recombinant human serum albumin, process for producing the same and pharmaceutical preparation containing the same
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US5728553A (en) * 1992-09-23 1998-03-17 Delta Biotechnology Limited High purity albumin and method of producing
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ATE205256T1 (de) * 1994-04-09 2001-09-15 Hoffmann La Roche Verfahren zur herstellung von alpha-interferon
JP3702474B2 (ja) * 1994-06-01 2005-10-05 三菱ウェルファーマ株式会社 血清アルブミン製剤の製造方法
RU2081122C1 (ru) * 1994-06-16 1997-06-10 Институт биоорганической химии им.М.М.Шемякина и Ю.А.Овчинникова РАН Способ выделения и очистки инсулина или его биотехнологических предшественников
US5486470A (en) * 1994-07-21 1996-01-23 Merck & Co., Inc. Purified herpes simplex virus protease and methods of purification
ES2211889T3 (es) 1994-08-31 2004-07-16 Mitsubishi Pharma Corporation Procedimiento para la purificacion de albumina de suero recombinante.
EP1736483A3 (en) * 1995-09-07 2008-07-30 Pharming Intellectual Property BV Purification of alpha-1 proteinase inhibitor
RU2132386C1 (ru) * 1997-06-20 1999-06-27 Государственный научный центр вирусологии и биотехнологии "Вектор" Способ получения рекомбинантного интерферона-гамма человека
GB9902000D0 (en) * 1999-01-30 1999-03-17 Delta Biotechnology Ltd Process

Also Published As

Publication number Publication date
HU0202124D0 (en:Method) 2002-09-28
DE60206847D1 (de) 2005-12-01
ITBO20010426A0 (it) 2001-07-06
CU23149A3 (es) 2006-06-29
BG106768A (en) 2003-05-30
RU2274471C2 (ru) 2006-04-20
KR20030005005A (ko) 2003-01-15
SK8592002A3 (en) 2003-01-09
PL209954B1 (pl) 2011-11-30
US20030010715A1 (en) 2003-01-16
CN1396176A (zh) 2003-02-12
EP1273592B1 (en) 2005-10-26
YU50502A (sh) 2005-09-19
JP2003096092A (ja) 2003-04-03
MXPA02006303A (es) 2003-02-10
SI1273592T1 (sl) 2006-02-28
CN100484954C (zh) 2009-05-06
HRP20020480B1 (en) 2006-11-30
EG23150A (en) 2004-05-31
RU2002117383A (ru) 2004-01-27
ATE307824T1 (de) 2005-11-15
ITBO20010426A1 (it) 2003-01-06
BG65748B1 (bg) 2009-09-30
RS51512B (sr) 2011-06-30
DZ3236A1 (fr) 2005-04-20
HUP0202124A2 (hu) 2003-10-28
SK287827B6 (sk) 2011-11-04
HRP20020480A2 (en) 2003-02-28
CA2388716C (en) 2008-01-08
KR100771252B1 (ko) 2007-10-30
PL354769A1 (en) 2003-01-13
ES2250544T3 (es) 2006-04-16
CA2388716A1 (en) 2003-01-06
EP1273592A3 (en) 2003-03-19
US6866782B2 (en) 2005-03-15
BR0202431A (pt) 2003-09-09
JP3940037B2 (ja) 2007-07-04
DE60206847T2 (de) 2006-07-06
DK1273592T3 (da) 2006-01-02
UY27354A1 (es) 2003-04-30
MEP3408A (en) 2010-10-10
EP1273592A2 (en) 2003-01-08

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