NO328930B1 - Platinumkompleks, inklusjonskompleks derav, fremgangsmate for fremstilling derav samt terapeutisk sammensetning - Google Patents

Platinumkompleks, inklusjonskompleks derav, fremgangsmate for fremstilling derav samt terapeutisk sammensetning Download PDF

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Publication number
NO328930B1
NO328930B1 NO20005990A NO20005990A NO328930B1 NO 328930 B1 NO328930 B1 NO 328930B1 NO 20005990 A NO20005990 A NO 20005990A NO 20005990 A NO20005990 A NO 20005990A NO 328930 B1 NO328930 B1 NO 328930B1
Authority
NO
Norway
Prior art keywords
complex
platinum
formula
carbon atoms
group
Prior art date
Application number
NO20005990A
Other languages
English (en)
Norwegian (no)
Other versions
NO20005990D0 (no
NO20005990L (no
Inventor
Milan Melka
Frantisek Zak
Adolf Mistr
Anna Poulova
Jaroslav Turanek
Dana Zaluska
Original Assignee
Pliva Lachema As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pliva Lachema As filed Critical Pliva Lachema As
Publication of NO20005990D0 publication Critical patent/NO20005990D0/no
Publication of NO20005990L publication Critical patent/NO20005990L/no
Publication of NO328930B1 publication Critical patent/NO328930B1/no

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086Platinum compounds
    • C07F15/0093Platinum compounds without a metal-carbon linkage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
NO20005990A 1998-05-27 2000-11-27 Platinumkompleks, inklusjonskompleks derav, fremgangsmate for fremstilling derav samt terapeutisk sammensetning NO328930B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CZ19981628A CZ288912B6 (cs) 1998-05-27 1998-05-27 Komplex platiny v oxidačním čísle IV, způsob přípravy tohoto komplexu, tento komplex jako léčivo a farmaceutická kompozice tento komplex obsahující
PCT/CZ1999/000015 WO1999061451A1 (en) 1998-05-27 1999-05-24 Platinum complex, its preparation and therapeutic application

Publications (3)

Publication Number Publication Date
NO20005990D0 NO20005990D0 (no) 2000-11-27
NO20005990L NO20005990L (no) 2000-11-27
NO328930B1 true NO328930B1 (no) 2010-06-21

Family

ID=5463562

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20005990A NO328930B1 (no) 1998-05-27 2000-11-27 Platinumkompleks, inklusjonskompleks derav, fremgangsmate for fremstilling derav samt terapeutisk sammensetning

Country Status (24)

Country Link
US (1) US6503943B1 (cs)
EP (1) EP1082330B1 (cs)
JP (1) JP3575686B2 (cs)
CN (1) CN1124279C (cs)
AU (1) AU741380B2 (cs)
BG (1) BG64599B1 (cs)
BR (1) BR9910669B1 (cs)
CA (1) CA2332054C (cs)
CZ (1) CZ288912B6 (cs)
DE (1) DE69901177T2 (cs)
ES (1) ES2175968T3 (cs)
HR (1) HRP20000791B1 (cs)
HU (1) HU224716B1 (cs)
IL (1) IL139529A (cs)
MX (1) MXPA00011621A (cs)
NO (1) NO328930B1 (cs)
PL (1) PL191132B1 (cs)
PT (1) PT1082330E (cs)
RS (1) RS49738B (cs)
RU (1) RU2200164C2 (cs)
SI (1) SI1082330T1 (cs)
SK (1) SK284436B6 (cs)
UA (1) UA56315C2 (cs)
WO (1) WO1999061451A1 (cs)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ296045B6 (cs) * 2003-03-31 2005-12-14 Pliva-Lachema A. S. Farmaceutická kompozice obsahující jako účinnou látku komplex čtyřmocné platiny a způsob její výroby
CZ295584B6 (cs) * 2004-02-12 2005-08-17 Pliva-Lachema A. S. Farmaceutická kompozice obsahující jako účinnou látku platinový komplex a způsob výroby této kompozice
WO2004087126A1 (en) * 2003-03-31 2004-10-14 Pliva-Lachema A.S. Pharmaceutical composition containing platinum complex as active substance and method of manufacturing thereof
US20080146555A1 (en) 2004-06-18 2008-06-19 Gpc Biotech, Inc Uses of Kinase Inhibitors and Compositions Thereof
EP1781230A1 (en) * 2004-07-14 2007-05-09 GPC Biotech AG Variable-dose packaging system
CZ296169B6 (cs) * 2004-09-08 2006-01-11 Pliva - Lachema A. S. Farmaceutická kompozice pro rektální nebo vaginální podání, zpusob její prípravy a tato kompozice pro pouzití jako lécivo
CZ2004964A3 (cs) * 2004-09-14 2006-03-15 Pliva-Lachema A. S. Perorální farmaceutická kompozice pro cílený transport komplexu platiny do kolorektální oblasti, zpusob její prípravy a tato kompozice pro pouzití jako lécivo
US7977500B2 (en) * 2004-11-10 2011-07-12 University Of South Florida Platinum complexes for targeted drug delivery
US20090047365A1 (en) * 2005-02-28 2009-02-19 Eisai R & D Management Co., Ltd. Novel Concomitant Use of Sulfonamide Compound with Anti-Cancer Agent
EP1792622A1 (en) 2005-11-11 2007-06-06 GPC Biotech AG Anti-proliferative combination therapy comprising a platinum-based chemotherapeutic agent and EGFR inhibitors or pyrimidine analogues
CZ300120B6 (cs) * 2006-06-20 2009-02-11 Pliva - Lachema A. S. Farmaceutická kompozice pro injekcní podání
CZ300590B6 (cs) * 2006-06-20 2009-06-24 Pliva - Lachema A. S. Farmaceutická kompozice pro injekcní podání
CZ300424B6 (cs) * 2006-06-20 2009-05-13 Pliva - Lachema A. S. Farmaceutická kompozice pro perorální podání
KR100829173B1 (ko) * 2006-09-19 2008-05-13 광주과학기술원 물에 대한 용해도가 우수한 플라틴 복합체의 포접복합체 및그 제조방법
GB2457453B (en) * 2008-02-12 2010-05-12 Pliva Lachema As Polymorphic crystalline form III of (OC-6-43)-bis(acetate)(1-tricyclo[3,3,1,13,7]decylamine) ammine dichloroplatinum (IV)
GB2457455B (en) * 2008-02-12 2010-04-21 Pliva Lachema As Polymorphic crystalline form (I) of (OC-6-43)-Bis(Acetato)-1-(Tricyclo[3,3,1,1 (3,7)]Decylamine)Amminedichloroplatinum(IV)
GB2457452B (en) * 2008-02-12 2010-05-12 Pliva Lachema As Amorphous form of (OC-6-43)-bis(acetate)(1-tricyclo[3,3,1,13,7]decylamine) amminedichloroplatinum (IV)
GB2457454B (en) * 2008-02-12 2010-05-12 Pliva Lachema As Polymorphic crystalline form II of (OC-6-43)-bis(acetate)(1-tricyclo[3,3,1,13,7]decylamine) ammine dichloroplatinum (IV)
WO2010149666A1 (en) 2009-06-22 2010-12-29 Medexis S.A. Methods for treating neoplasia
US20120238488A1 (en) 2009-09-08 2012-09-20 Konstantinos Alevizopoulos Compounds and methods for treating neoplasia
WO2012013816A1 (en) 2010-07-30 2012-02-02 Medexis S.A. Compounds and methods for treating neoplasia
EP3189064B1 (en) 2014-09-03 2018-08-08 Vuab Pharma A. S. Platinum (iv) complex with increased antitumor efficacy
CN104984356A (zh) * 2015-05-14 2015-10-21 昆明贵研药业有限公司 赛特铂的环糊精复合物及制备方法
RU2613513C2 (ru) * 2015-07-17 2017-03-16 Федеральное государственное бюджетное учреждение науки Институт проблем химической физики Российской академии наук (ИПХФ РАН) Способ получения комплексов платины (IV) с аминонитроксильными радикалами
RU2726826C2 (ru) * 2016-12-27 2020-07-15 Общество с ограниченной ответственностью "Плат-АН" (ООО "Плат-АН") Композиция на основе аминонитроксильного комплекса платины и доксорубицина и способ лечения опухолей
JP7386972B2 (ja) * 2019-09-05 2023-11-27 ブイユーエービー ファーマ エー.エス. 実質的に増加した抗腫瘍効果を有する新規白金iv錯体

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE113054T1 (de) * 1988-02-02 1994-11-15 Johnson Matthey Inc Pt(iv) komplexe.
FI905018A0 (fi) * 1989-10-17 1990-10-12 Bristol Myers Squibb Co I vatten och loesningsmedel loesliga axiala hydroxi-och mono- och dikarboxylsyraderivat med stor tumoeraktivitet.
GB9105037D0 (en) * 1991-03-09 1991-04-24 Johnson Matthey Plc Improvements in chemical compounds
JPH10265380A (ja) * 1997-03-17 1998-10-06 Bristol Myers Squibb Co 抗ガン剤

Also Published As

Publication number Publication date
DE69901177D1 (de) 2002-05-08
HUP0102549A3 (en) 2004-04-28
EP1082330B1 (en) 2002-04-03
PT1082330E (pt) 2002-09-30
CA2332054A1 (en) 1999-12-02
WO1999061451A1 (en) 1999-12-02
AU3809399A (en) 1999-12-13
RS49738B (sr) 2008-04-04
JP3575686B2 (ja) 2004-10-13
NO20005990D0 (no) 2000-11-27
DE69901177T2 (de) 2002-10-02
BG104972A (en) 2001-08-31
CZ288912B6 (cs) 2001-09-12
SK17732000A3 (sk) 2001-05-10
IL139529A0 (en) 2001-11-25
ES2175968T3 (es) 2002-11-16
CA2332054C (en) 2005-06-28
AU741380B2 (en) 2001-11-29
MXPA00011621A (es) 2003-03-12
IL139529A (en) 2004-06-20
HUP0102549A2 (hu) 2001-11-28
BR9910669B1 (pt) 2011-07-26
YU71900A (sh) 2002-10-18
RU2200164C2 (ru) 2003-03-10
UA56315C2 (uk) 2003-05-15
EP1082330A1 (en) 2001-03-14
HRP20000791B1 (en) 2006-07-31
BR9910669A (pt) 2001-01-30
JP2002516332A (ja) 2002-06-04
US6503943B1 (en) 2003-01-07
SI1082330T1 (en) 2002-08-31
PL191132B1 (pl) 2006-03-31
NO20005990L (no) 2000-11-27
PL344346A1 (en) 2001-11-05
BG64599B1 (bg) 2005-08-31
HU224716B1 (en) 2006-01-30
CN1303388A (zh) 2001-07-11
CN1124279C (zh) 2003-10-15
HRP20000791A2 (en) 2001-02-28
SK284436B6 (sk) 2005-04-01
CZ162898A3 (cs) 1999-12-15

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