RS49738B - Kompleks platine, njegovo dobijanje i terapeutska primena - Google Patents

Kompleks platine, njegovo dobijanje i terapeutska primena

Info

Publication number
RS49738B
RS49738B YUP-719/00A YU71900A RS49738B RS 49738 B RS49738 B RS 49738B YU 71900 A YU71900 A YU 71900A RS 49738 B RS49738 B RS 49738B
Authority
RS
Serbia
Prior art keywords
platinum complex
preparation
carbon atoms
therapeutic application
halogen atom
Prior art date
Application number
YUP-719/00A
Other languages
English (en)
Inventor
Frantisek Žak
Adolf Mistr
Anna Poulova
Milan Melka
Jaroslav Turanek
Dana Zaluska
Original Assignee
Pliva-Lachema A.S.,
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pliva-Lachema A.S., filed Critical Pliva-Lachema A.S.,
Publication of YU71900A publication Critical patent/YU71900A/sh
Publication of RS49738B publication Critical patent/RS49738B/sr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)

Abstract

Kompleks platine sa oksidacionim brojem IV formule (I): naznačen time, što je X, atom halogena, B je, nezavisno jedan od drugog, atom halogena, hidroksilna grupa ili karboksilatna grupa koja sadrži 1 do 6 atoma ugljenika, i A je –NH2-R grupa, gde je R triciklična ugljovodonična grupa koji sadrži 10 do 14 atoma ugljenika, koji mogu po potrebi da budu supstituisani na tricikličnom prstenu jednom ili dve alkil grupe od kojih svaka sadrži 1 do 4 atoma ugljenika. Prijava sadrži još 7 zahteva.
YUP-719/00A 1998-05-27 1999-05-24 Kompleks platine, njegovo dobijanje i terapeutska primena RS49738B (sr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CZ19981628A CZ288912B6 (cs) 1998-05-27 1998-05-27 Komplex platiny v oxidačním čísle IV, způsob přípravy tohoto komplexu, tento komplex jako léčivo a farmaceutická kompozice tento komplex obsahující

Publications (2)

Publication Number Publication Date
YU71900A YU71900A (sh) 2002-10-18
RS49738B true RS49738B (sr) 2008-04-04

Family

ID=5463562

Family Applications (1)

Application Number Title Priority Date Filing Date
YUP-719/00A RS49738B (sr) 1998-05-27 1999-05-24 Kompleks platine, njegovo dobijanje i terapeutska primena

Country Status (24)

Country Link
US (1) US6503943B1 (sr)
EP (1) EP1082330B1 (sr)
JP (1) JP3575686B2 (sr)
CN (1) CN1124279C (sr)
AU (1) AU741380B2 (sr)
BG (1) BG64599B1 (sr)
BR (1) BR9910669B1 (sr)
CA (1) CA2332054C (sr)
CZ (1) CZ288912B6 (sr)
DE (1) DE69901177T2 (sr)
ES (1) ES2175968T3 (sr)
HR (1) HRP20000791B1 (sr)
HU (1) HU224716B1 (sr)
IL (1) IL139529A (sr)
MX (1) MXPA00011621A (sr)
NO (1) NO328930B1 (sr)
PL (1) PL191132B1 (sr)
PT (1) PT1082330E (sr)
RS (1) RS49738B (sr)
RU (1) RU2200164C2 (sr)
SI (1) SI1082330T1 (sr)
SK (1) SK284436B6 (sr)
UA (1) UA56315C2 (sr)
WO (1) WO1999061451A1 (sr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ296045B6 (cs) * 2003-03-31 2005-12-14 Pliva-Lachema A. S. Farmaceutická kompozice obsahující jako účinnou látku komplex čtyřmocné platiny a způsob její výroby
CZ295584B6 (cs) * 2004-02-12 2005-08-17 Pliva-Lachema A. S. Farmaceutická kompozice obsahující jako účinnou látku platinový komplex a způsob výroby této kompozice
WO2004087126A1 (en) * 2003-03-31 2004-10-14 Pliva-Lachema A.S. Pharmaceutical composition containing platinum complex as active substance and method of manufacturing thereof
US20080146555A1 (en) 2004-06-18 2008-06-19 Gpc Biotech, Inc Uses of Kinase Inhibitors and Compositions Thereof
US20080272022A1 (en) * 2004-07-14 2008-11-06 Gpc Biotech Ag Variable-Dose Packaging System
CZ2004945A3 (cs) * 2004-09-08 2006-01-11 Pliva - Lachema A. S. Farmaceutická kompozice pro rektální nebo vaginální podání, zpusob její prípravy a tato kompozice pro pouzití jako lécivo
CZ2004964A3 (cs) * 2004-09-14 2006-03-15 Pliva-Lachema A. S. Perorální farmaceutická kompozice pro cílený transport komplexu platiny do kolorektální oblasti, zpusob její prípravy a tato kompozice pro pouzití jako lécivo
EP1819716A4 (en) * 2004-11-10 2010-02-17 Univ South Florida PLATINUM COMPLEXES FOR MEDICINAL PRODUCTS LAID DOWN
US20090047365A1 (en) * 2005-02-28 2009-02-19 Eisai R & D Management Co., Ltd. Novel Concomitant Use of Sulfonamide Compound with Anti-Cancer Agent
EP1792622A1 (en) 2005-11-11 2007-06-06 GPC Biotech AG Anti-proliferative combination therapy comprising a platinum-based chemotherapeutic agent and EGFR inhibitors or pyrimidine analogues
CZ300590B6 (cs) * 2006-06-20 2009-06-24 Pliva - Lachema A. S. Farmaceutická kompozice pro injekcní podání
CZ300120B6 (cs) * 2006-06-20 2009-02-11 Pliva - Lachema A. S. Farmaceutická kompozice pro injekcní podání
CZ300424B6 (cs) * 2006-06-20 2009-05-13 Pliva - Lachema A. S. Farmaceutická kompozice pro perorální podání
KR100829173B1 (ko) * 2006-09-19 2008-05-13 광주과학기술원 물에 대한 용해도가 우수한 플라틴 복합체의 포접복합체 및그 제조방법
GB2457454B (en) * 2008-02-12 2010-05-12 Pliva Lachema As Polymorphic crystalline form II of (OC-6-43)-bis(acetate)(1-tricyclo[3,3,1,13,7]decylamine) ammine dichloroplatinum (IV)
GB2457455B (en) * 2008-02-12 2010-04-21 Pliva Lachema As Polymorphic crystalline form (I) of (OC-6-43)-Bis(Acetato)-1-(Tricyclo[3,3,1,1 (3,7)]Decylamine)Amminedichloroplatinum(IV)
GB2457452B (en) * 2008-02-12 2010-05-12 Pliva Lachema As Amorphous form of (OC-6-43)-bis(acetate)(1-tricyclo[3,3,1,13,7]decylamine) amminedichloroplatinum (IV)
GB2457453B (en) * 2008-02-12 2010-05-12 Pliva Lachema As Polymorphic crystalline form III of (OC-6-43)-bis(acetate)(1-tricyclo[3,3,1,13,7]decylamine) ammine dichloroplatinum (IV)
WO2010149666A1 (en) 2009-06-22 2010-12-29 Medexis S.A. Methods for treating neoplasia
WO2011029639A2 (en) 2009-09-08 2011-03-17 Medexis S.A. Compounds and methods for treating neoplasia
WO2012013816A1 (en) 2010-07-30 2012-02-02 Medexis S.A. Compounds and methods for treating neoplasia
AU2014405305B2 (en) 2014-09-03 2019-09-19 Vuab Pharma A.S. Platinum (IV) complex with increased antitumor efficacy
CN104984356A (zh) * 2015-05-14 2015-10-21 昆明贵研药业有限公司 赛特铂的环糊精复合物及制备方法
RU2613513C2 (ru) * 2015-07-17 2017-03-16 Федеральное государственное бюджетное учреждение науки Институт проблем химической физики Российской академии наук (ИПХФ РАН) Способ получения комплексов платины (IV) с аминонитроксильными радикалами
RU2726826C2 (ru) * 2016-12-27 2020-07-15 Общество с ограниченной ответственностью "Плат-АН" (ООО "Плат-АН") Композиция на основе аминонитроксильного комплекса платины и доксорубицина и способ лечения опухолей
DK4025581T3 (da) * 2019-09-05 2024-02-26 Vuab Pharma A S Nye platin-(IV)-komplekser med en væsentligt forhøjet anti-tumorvirkning

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE113054T1 (de) * 1988-02-02 1994-11-15 Johnson Matthey Inc Pt(iv) komplexe.
FI905018A0 (fi) * 1989-10-17 1990-10-12 Bristol Myers Squibb Co I vatten och loesningsmedel loesliga axiala hydroxi-och mono- och dikarboxylsyraderivat med stor tumoeraktivitet.
GB9105037D0 (en) * 1991-03-09 1991-04-24 Johnson Matthey Plc Improvements in chemical compounds
JPH10265380A (ja) * 1997-03-17 1998-10-06 Bristol Myers Squibb Co 抗ガン剤

Also Published As

Publication number Publication date
EP1082330B1 (en) 2002-04-03
SK17732000A3 (sk) 2001-05-10
NO20005990L (no) 2000-11-27
BR9910669A (pt) 2001-01-30
HUP0102549A2 (hu) 2001-11-28
CA2332054A1 (en) 1999-12-02
DE69901177D1 (de) 2002-05-08
WO1999061451A1 (en) 1999-12-02
NO20005990D0 (no) 2000-11-27
SK284436B6 (sk) 2005-04-01
DE69901177T2 (de) 2002-10-02
PL344346A1 (en) 2001-11-05
MXPA00011621A (es) 2003-03-12
BG64599B1 (bg) 2005-08-31
BR9910669B1 (pt) 2011-07-26
CN1303388A (zh) 2001-07-11
IL139529A (en) 2004-06-20
ES2175968T3 (es) 2002-11-16
PL191132B1 (pl) 2006-03-31
HRP20000791B1 (en) 2006-07-31
AU3809399A (en) 1999-12-13
JP3575686B2 (ja) 2004-10-13
BG104972A (en) 2001-08-31
CN1124279C (zh) 2003-10-15
JP2002516332A (ja) 2002-06-04
HRP20000791A2 (en) 2001-02-28
PT1082330E (pt) 2002-09-30
HU224716B1 (en) 2006-01-30
CA2332054C (en) 2005-06-28
CZ288912B6 (cs) 2001-09-12
SI1082330T1 (en) 2002-08-31
YU71900A (sh) 2002-10-18
EP1082330A1 (en) 2001-03-14
RU2200164C2 (ru) 2003-03-10
AU741380B2 (en) 2001-11-29
CZ162898A3 (cs) 1999-12-15
US6503943B1 (en) 2003-01-07
IL139529A0 (en) 2001-11-25
HUP0102549A3 (en) 2004-04-28
NO328930B1 (no) 2010-06-21
UA56315C2 (uk) 2003-05-15

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