ATE35137T1 - Thieno(2,3-d)pyrimidin-derivate und deren salze. - Google Patents

Thieno(2,3-d)pyrimidin-derivate und deren salze.

Info

Publication number
ATE35137T1
ATE35137T1 AT84116052T AT84116052T ATE35137T1 AT E35137 T1 ATE35137 T1 AT E35137T1 AT 84116052 T AT84116052 T AT 84116052T AT 84116052 T AT84116052 T AT 84116052T AT E35137 T1 ATE35137 T1 AT E35137T1
Authority
AT
Austria
Prior art keywords
sup
carbon atoms
salts
alkyl group
pyrimidine derivatives
Prior art date
Application number
AT84116052T
Other languages
English (en)
Inventor
Kunihiro Ninomiya
Issei Nitta
Akihiro Tobe
Mitsuo Egawa
Ryoji Kikumoto
Original Assignee
Mitsubishi Chem Ind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Chem Ind filed Critical Mitsubishi Chem Ind
Application granted granted Critical
Publication of ATE35137T1 publication Critical patent/ATE35137T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
AT84116052T 1984-01-05 1984-12-21 Thieno(2,3-d)pyrimidin-derivate und deren salze. ATE35137T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP59000479A JPS60146891A (ja) 1984-01-05 1984-01-05 〔２，３−ｄ〕チエノピリミジン誘導体およびその塩
EP84116052A EP0150469B1 (de) 1984-01-05 1984-12-21 Thieno(2,3-d)pyrimidin-Derivate und deren Salze

Publications (1)

Publication Number Publication Date
ATE35137T1 true ATE35137T1 (de) 1988-07-15

Family

ID=11474905

Family Applications (1)

Application Number Title Priority Date Filing Date
AT84116052T ATE35137T1 (de) 1984-01-05 1984-12-21 Thieno(2,3-d)pyrimidin-derivate und deren salze.

Country Status (8)

Country Link
US (1) US4695568A (de)
EP (1) EP0150469B1 (de)
JP (1) JPS60146891A (de)
AT (1) ATE35137T1 (de)
CA (1) CA1224782A (de)
DE (1) DE3472106D1 (de)
DK (1) DK165744C (de)
HU (1) HU191161B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4734418A (en) * 1984-12-14 1988-03-29 Mitsui Petrochemical Industries, Ltd. Quinazoline compounds and antihypertensives
US4703120A (en) * 1986-04-28 1987-10-27 Ortho Pharmaceutical Corporation Furo(3,4-d)pyrimidine-2,4-dione derivatives and intermediates thereof
GB8912335D0 (en) * 1989-05-30 1989-07-12 Smithkline Beckman Intercredit Compounds
DE19636769A1 (de) * 1996-09-10 1998-03-12 Basf Ag 3-Substituierte Pyrido [4',3':4,5]thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung
JPH10298078A (ja) * 1997-05-06 1998-11-10 Mitsubishi Chem Corp 抗不安薬
GB0216027D0 (en) 2002-07-10 2002-08-21 Arachnova Therapeutics Ltd New therapeutic use
GB0112494D0 (en) * 2001-05-22 2001-07-11 Arachnova Therapeutics Ltd New therapeutic use
DE60326585D1 (de) * 2002-07-10 2009-04-23 Dynogen Pharmaceuticals Inc 4-(2-fluorophenyl)-6-methyl-2(1-piperazinyl)thieno(2,3-d) pyrimidin bei der behandlung von funktionalen darmstörungen
DE10232750A1 (de) * 2002-07-18 2004-02-05 Basf Ag Verfahren zur Herstellung von macrocyclischen Ketonen durch Dieckmann-Kondensation in der Gasphase
US20060167005A1 (en) * 2002-08-29 2006-07-27 David Cavalla New therapeutic uses of (4-(2-fluorophenyl)-6-methyl-2-(1-piperazinyl) thieno [2,3-d] pyrimidine
BRPI0406749A (pt) * 2003-01-13 2005-12-20 Dynogen Pharmaceuticals Inc Métodos relacionados ao tratamento de distúrbios fincionais do intestino e composição farmacêutica
ATE359079T1 (de) * 2003-01-13 2007-05-15 Dynogen Pharmaceuticals Inc Verfahren zur behandlung von übelkeit, erbrechen, würgereiz oder jede kombination daraus
ATE365554T1 (de) * 2003-04-04 2007-07-15 Dynogen Pharmaceuticals Inc Methode zur behandlung von erkrankungen der unteren harnwege
WO2005002583A1 (en) * 2003-07-07 2005-01-13 Mitsubishi Pharma Corporation Use of thieno`2,3-d ! pyrimidines for the prophylaxis or treatment of hyperactivity disorder
US20060293309A1 (en) * 2005-03-28 2006-12-28 Dynogen Pharmaceuticals, Inc. Method of treating disorders and conditions using peripherally-restricted antagonists and inhibitors
WO2007120445A1 (en) * 2006-03-31 2007-10-25 Dynogen Pharmaceuticals, Inc. SOLUBLE SALTS OF THIENO [2,3-d] PYRIMIDINE DERIVATIVES
EP2016082A2 (de) * 2006-03-31 2009-01-21 Dynogen Pharmaceuticals, Inc. Kristalline formen von 4-(2-fluorophenyl)-6-methyl-2-(piperazin-1-yl)-thien-(2,3-d)-pyrimidin
EP2947084B8 (de) * 2013-01-18 2021-03-10 Guangzhou Maxinovel Pharmaceuticals Co. Fünf- oder sechsendige heterocyclische verbindung und herstellungsverfahren, pharmazeutische zusammensetzung und verwendung davon

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3883651A (en) * 1969-08-08 1975-05-13 Boehringer Sohn Ingelheim Pharmaceutical compositions containing a 2-(aminoalkylamino)-4-amino-thieno{8 3,2-d{9 pyrimidine and method of use
US4054656A (en) * 1975-09-10 1977-10-18 Mead Johnson & Company Thieno[2,3-d]pyrimidine antiallergic agents
GB1570494A (en) * 1975-11-28 1980-07-02 Ici Ltd Thienopyrimidine derivatives and their use as pesticides
ZA782648B (en) * 1977-05-23 1979-06-27 Ici Australia Ltd The prevention,control or eradication of infestations of ixodid ticks
US4471117A (en) * 1979-06-21 1984-09-11 Janssen Pharmaceutica N.V. 3,4-Dihydro-2H-pyrimido(2,1-b)benzothiazoles
JPS5692875A (en) * 1979-12-27 1981-07-27 Dainippon Pharmaceut Co Ltd 2-aminoquinazoline derivative
FI824314L (fi) * 1981-12-16 1983-06-17 Sankyo Co Thienopyrimidin-derivater, deras framstaellning och deras medicinska anvaendning
FR2521144A1 (fr) * 1982-02-08 1983-08-12 Sanofi Sa Nouveaux derives de la piperazinyl-2 phenyl-4 quinazoline possedant des proprietes antidepressives, methode de preparation desdits composes et medicaments en contenant

Also Published As

Publication number Publication date
DK617184A (da) 1985-07-06
HUT37435A (en) 1985-12-28
DK165744B (da) 1993-01-11
US4695568A (en) 1987-09-22
EP0150469A1 (de) 1985-08-07
DK165744C (da) 1993-06-07
JPH0367071B2 (de) 1991-10-21
EP0150469B1 (de) 1988-06-15
CA1224782A (en) 1987-07-28
HU191161B (en) 1987-01-28
DK617184D0 (da) 1984-12-20
DE3472106D1 (en) 1988-07-21
JPS60146891A (ja) 1985-08-02

Similar Documents

Publication Publication Date Title
ATE35137T1 (de) Thieno(2,3-d)pyrimidin-derivate und deren salze.
ATE37179T1 (de) Dihydropyridazinone.
HUT52059A (en) Process for producing pharmaceutical compositions and new quinoline derivatives as a group of active components
ES2000346A6 (es) Un procedimiento para la preparacion de derivados de distamicina
GR3004250T3 (de)
ES8802148A1 (es) Procedimiento para preparar derivados de acido quinoloncarboxilico
TW429255B (en) Pyrazine compounds having treatment of central nervous system diseases and disorders
ES2046641T3 (es) Composicion antitumoral.
ES2005031A6 (es) Procedimiento para la obtencion de 1,3-dioxolanos 2,4-disustituidos.
ATE148128T1 (de) Anthracyclinglycosid-derivate und verfahren zu ihrer herstellung
ES2003086A6 (es) Procedimiento de obtencion de tienoquinolicinsulfonamidas
FR2608598B1 (fr) Nouveaux derives de l'indane, leur procede de preparation et les nouveaux intermediaires ainsi obtenus, leur application comme medicaments et les compositions les renfermant
FI861947A (fi) Hexensyror.
EP0347880A3 (de) Imidazo[2,1-b]benzothiazol-Verbindungen und diese enthaltende Antiulkus-Zubereitungen
HK1032916A1 (en) N,n'-bis(sulfonyl)hydrazines useful as antineoplastic agents
DE3268541D1 (en) Benzodioxane-imidazoline compounds, their preparation and use
ES8300776A1 (es) Procedimiento para la obtencion de nuevos derivados de la tiazolo (3,2-a)pirimidina
ES8502981A1 (es) Procedimiento de preparacion de derivados de piperacina.
ES2010225A6 (es) Procedimiento de preparacion de nuevos derivados de piperazina diona-2,6.
ES8705427A1 (es) Un procedimiento para la preparacion de nuevas 3-alcoxi-2-(n-pirrolidino)-n-pirimidinil- o n-pirazinil-propilaminas
HUT41029A (en) Process for preparing dioxolo-benzisoxazole derivatives
TH4071A (th) ขบวนการสำหรับการเตรียมอนุพันธ์ชนิดใหม่ของควินอลดินเอมีด

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EEFA Change of the company name
REN Ceased due to non-payment of the annual fee