ATE35137T1 - Thieno(2,3-d)pyrimidin-derivate und deren salze. - Google Patents
Thieno(2,3-d)pyrimidin-derivate und deren salze.Info
- Publication number
- ATE35137T1 ATE35137T1 AT84116052T AT84116052T ATE35137T1 AT E35137 T1 ATE35137 T1 AT E35137T1 AT 84116052 T AT84116052 T AT 84116052T AT 84116052 T AT84116052 T AT 84116052T AT E35137 T1 ATE35137 T1 AT E35137T1
- Authority
- AT
- Austria
- Prior art keywords
- sup
- carbon atoms
- salts
- alkyl group
- pyrimidine derivatives
- Prior art date
Links
- 150000003839 salts Chemical class 0.000 title abstract 2
- DDWBRNXDKNIQDY-UHFFFAOYSA-N thieno[2,3-d]pyrimidine Chemical class N1=CN=C2SC=CC2=C1 DDWBRNXDKNIQDY-UHFFFAOYSA-N 0.000 title abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 5
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical class [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 125000000175 2-thienyl group Chemical group S1C([*])=C([H])C([H])=C1[H] 0.000 abstract 1
- 125000001541 3-thienyl group Chemical group S1C([H])=C([*])C([H])=C1[H] 0.000 abstract 1
- 210000004556 brain Anatomy 0.000 abstract 1
- 125000002993 cycloalkylene group Chemical group 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000004064 dysfunction Effects 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Psychiatry (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP59000479A JPS60146891A (ja) | 1984-01-05 | 1984-01-05 | 〔２，３−ｄ〕チエノピリミジン誘導体およびその塩 |
| EP84116052A EP0150469B1 (de) | 1984-01-05 | 1984-12-21 | Thieno(2,3-d)pyrimidin-Derivate und deren Salze |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE35137T1 true ATE35137T1 (de) | 1988-07-15 |
Family
ID=11474905
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT84116052T ATE35137T1 (de) | 1984-01-05 | 1984-12-21 | Thieno(2,3-d)pyrimidin-derivate und deren salze. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US4695568A (de) |
| EP (1) | EP0150469B1 (de) |
| JP (1) | JPS60146891A (de) |
| AT (1) | ATE35137T1 (de) |
| CA (1) | CA1224782A (de) |
| DE (1) | DE3472106D1 (de) |
| DK (1) | DK165744C (de) |
| HU (1) | HU191161B (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1307786C (en) * | 1984-12-14 | 1992-09-22 | Keiichi Yokoyama | Quinazoline derivatives and antihypertensive preparations containing same as effective components |
| US4703120A (en) * | 1986-04-28 | 1987-10-27 | Ortho Pharmaceutical Corporation | Furo(3,4-d)pyrimidine-2,4-dione derivatives and intermediates thereof |
| GB8912335D0 (en) * | 1989-05-30 | 1989-07-12 | Smithkline Beckman Intercredit | Compounds |
| DE19636769A1 (de) * | 1996-09-10 | 1998-03-12 | Basf Ag | 3-Substituierte Pyrido [4',3':4,5]thieno[2,3-d]pyrimidin-Derivate, ihre Herstellung und Verwendung |
| JPH10298078A (ja) * | 1997-05-06 | 1998-11-10 | Mitsubishi Chem Corp | 抗不安薬 |
| GB0112494D0 (en) * | 2001-05-22 | 2001-07-11 | Arachnova Therapeutics Ltd | New therapeutic use |
| GB0216027D0 (en) | 2002-07-10 | 2002-08-21 | Arachnova Therapeutics Ltd | New therapeutic use |
| AU2003255712B2 (en) * | 2002-07-10 | 2007-03-15 | Arachnova Therapeutics Ltd. | 4-(2-fluorophenyl)-6-methyl-2(1-piperazinyl)thieno(2,3-D) pyrimidine in the treatment of functional bowel disorder |
| DE10232750A1 (de) * | 2002-07-18 | 2004-02-05 | Basf Ag | Verfahren zur Herstellung von macrocyclischen Ketonen durch Dieckmann-Kondensation in der Gasphase |
| JP2006500427A (ja) * | 2002-08-29 | 2006-01-05 | アラクノーバ・セラピューティックス・リミテッド | （４−（２−フルオロフェニル）−６−メチル−２−（１−ピペラジニル）チエノ［２，３−ｄ］ピリミジンの新規治療的使用 |
| BRPI0406749A (pt) * | 2003-01-13 | 2005-12-20 | Dynogen Pharmaceuticals Inc | Métodos relacionados ao tratamento de distúrbios fincionais do intestino e composição farmacêutica |
| AU2004204827B2 (en) * | 2003-01-13 | 2006-06-29 | Dynogen Pharmaceuticals, Inc. | Method of treating nausea, vomiting, retching or any combination thereof |
| ATE365554T1 (de) * | 2003-04-04 | 2007-07-15 | Dynogen Pharmaceuticals Inc | Methode zur behandlung von erkrankungen der unteren harnwege |
| WO2005002583A1 (en) * | 2003-07-07 | 2005-01-13 | Mitsubishi Pharma Corporation | Use of thieno`2,3-d ! pyrimidines for the prophylaxis or treatment of hyperactivity disorder |
| WO2006105117A2 (en) * | 2005-03-28 | 2006-10-05 | Dynogen Pharmaceuticals, Inc. | Method of treating disorders and conditions using peripherally-restricted antagonists and inhibitors |
| WO2007120445A1 (en) * | 2006-03-31 | 2007-10-25 | Dynogen Pharmaceuticals, Inc. | SOLUBLE SALTS OF THIENO [2,3-d] PYRIMIDINE DERIVATIVES |
| JP2009532357A (ja) * | 2006-03-31 | 2009-09-10 | ダイノジェン ファーマシューティカルズ， インコーポレイテッド | ４−（２−フルオロフェニル）−６−メチル−２−（ピペラジン−１−イル）チエノ（２，３−ｄ）ピリミジンの結晶形態 |
| DK2947084T3 (da) * | 2013-01-18 | 2020-11-02 | Guangzhou Maxinovel Pharmaceuticals Co | Fem- og seks-ledet heterocyklisk forbindelse og forberedelsesmetode, farmaceutisk sammensætning og anvendelse deraf |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3883651A (en) * | 1969-08-08 | 1975-05-13 | Boehringer Sohn Ingelheim | Pharmaceutical compositions containing a 2-(aminoalkylamino)-4-amino-thieno{8 3,2-d{9 pyrimidine and method of use |
| US4054656A (en) * | 1975-09-10 | 1977-10-18 | Mead Johnson & Company | Thieno[2,3-d]pyrimidine antiallergic agents |
| GB1570494A (en) * | 1975-11-28 | 1980-07-02 | Ici Ltd | Thienopyrimidine derivatives and their use as pesticides |
| ZA782648B (en) * | 1977-05-23 | 1979-06-27 | Ici Australia Ltd | The prevention,control or eradication of infestations of ixodid ticks |
| US4471117A (en) * | 1979-06-21 | 1984-09-11 | Janssen Pharmaceutica N.V. | 3,4-Dihydro-2H-pyrimido(2,1-b)benzothiazoles |
| JPS5692875A (en) * | 1979-12-27 | 1981-07-27 | Dainippon Pharmaceut Co Ltd | 2-aminoquinazoline derivative |
| FI824314A7 (fi) * | 1981-12-16 | 1983-06-17 | Sankyo Co | Thienopyrimidiinijohdannaiset, niiden valmistus ja niiden lääketieteellinen käyttö. |
| FR2521144A1 (fr) * | 1982-02-08 | 1983-08-12 | Sanofi Sa | Nouveaux derives de la piperazinyl-2 phenyl-4 quinazoline possedant des proprietes antidepressives, methode de preparation desdits composes et medicaments en contenant |
-
1984
- 1984-01-05 JP JP59000479A patent/JPS60146891A/ja active Granted
- 1984-12-20 DK DK617184A patent/DK165744C/da not_active IP Right Cessation
- 1984-12-21 AT AT84116052T patent/ATE35137T1/de not_active IP Right Cessation
- 1984-12-21 EP EP84116052A patent/EP0150469B1/de not_active Expired
- 1984-12-21 DE DE8484116052T patent/DE3472106D1/de not_active Expired
- 1984-12-24 US US06/685,768 patent/US4695568A/en not_active Expired - Lifetime
- 1984-12-28 CA CA000471183A patent/CA1224782A/en not_active Expired
-
1985
- 1985-01-03 HU HU8513A patent/HU191161B/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HUT37435A (en) | 1985-12-28 |
| JPH0367071B2 (de) | 1991-10-21 |
| EP0150469A1 (de) | 1985-08-07 |
| JPS60146891A (ja) | 1985-08-02 |
| DK617184D0 (da) | 1984-12-20 |
| US4695568A (en) | 1987-09-22 |
| EP0150469B1 (de) | 1988-06-15 |
| DK165744C (da) | 1993-06-07 |
| HU191161B (en) | 1987-01-28 |
| DE3472106D1 (en) | 1988-07-21 |
| DK165744B (da) | 1993-01-11 |
| CA1224782A (en) | 1987-07-28 |
| DK617184A (da) | 1985-07-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| EEFA | Change of the company name | ||
| REN | Ceased due to non-payment of the annual fee |