DK4025581T3 - Nye platin-(IV)-komplekser med en væsentligt forhøjet anti-tumorvirkning - Google Patents

Nye platin-(IV)-komplekser med en væsentligt forhøjet anti-tumorvirkning Download PDF

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Publication number
DK4025581T3
DK4025581T3 DK19765241.5T DK19765241T DK4025581T3 DK 4025581 T3 DK4025581 T3 DK 4025581T3 DK 19765241 T DK19765241 T DK 19765241T DK 4025581 T3 DK4025581 T3 DK 4025581T3
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DK
Denmark
Prior art keywords
complexes
significantly increased
tumor activity
increased anti
new platinum
Prior art date
Application number
DK19765241.5T
Other languages
English (en)
Inventor
Vladimír Kysilka
Jan Mengler
Milos Mikoska
Original Assignee
Vuab Pharma A S
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Publication date
Application filed by Vuab Pharma A S filed Critical Vuab Pharma A S
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Publication of DK4025581T3 publication Critical patent/DK4025581T3/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086Platinum compounds
    • C07F15/0093Platinum compounds without a metal-carbon linkage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK19765241.5T 2019-09-05 2019-09-05 Nye platin-(IV)-komplekser med en væsentligt forhøjet anti-tumorvirkning DK4025581T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2019/073686 WO2021043402A1 (en) 2019-09-05 2019-09-05 New platinum iv complexes with substantially increased antitumor efficacy

Publications (1)

Publication Number Publication Date
DK4025581T3 true DK4025581T3 (da) 2024-02-26

Family

ID=67874458

Family Applications (1)

Application Number Title Priority Date Filing Date
DK19765241.5T DK4025581T3 (da) 2019-09-05 2019-09-05 Nye platin-(IV)-komplekser med en væsentligt forhøjet anti-tumorvirkning

Country Status (11)

Country Link
US (1) US20220289781A1 (da)
EP (1) EP4025581B1 (da)
JP (1) JP7386972B2 (da)
CN (1) CN114341147B (da)
AU (1) AU2019464913A1 (da)
BR (1) BR112022003645A2 (da)
CA (1) CA3153380A1 (da)
DK (1) DK4025581T3 (da)
FI (1) FI4025581T3 (da)
IL (1) IL291110A (da)
WO (1) WO2021043402A1 (da)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE113054T1 (de) 1988-02-02 1994-11-15 Johnson Matthey Inc Pt(iv) komplexe.
CZ288912B6 (cs) 1998-05-27 2001-09-12 Lachema, A. S. Komplex platiny v oxidačním čísle IV, způsob přípravy tohoto komplexu, tento komplex jako léčivo a farmaceutická kompozice tento komplex obsahující
EP1622585A4 (en) * 2003-05-02 2009-07-01 Aronex Pharmaceuticals Inc LIPID-PLATINUM COMPLEXES AND APPLICATION METHOD THEREFOR
WO2010027428A1 (en) 2008-08-26 2010-03-11 Massachusetts Institute Of Technology Platinum ( iv) complexes for use in dual mode pharmaceutical therapy
CN102924528B (zh) * 2012-10-29 2015-04-15 东南大学 抗肿瘤二价铂配合物以及该配合物和其配体的制备方法
WO2014100417A1 (en) * 2012-12-19 2014-06-26 Blend Therapeutics, Inc. Compounds, compositions, and methods for the treatment of cancers
RU2666898C1 (ru) 2014-09-03 2018-09-13 Вуаб Фарма А.С. Комплексы платины (iv) с повышенной противораковой эффективностью
US20180186823A1 (en) 2015-06-23 2018-07-05 Placon Therapeutics, Inc. Platinum compounds, compositions, and uses thereof
CN110183494B (zh) * 2019-05-20 2023-01-24 昆明贵研药业有限公司 一种可口服的新型抗肿瘤Pt(IV)配合物制备方法及其应用

Also Published As

Publication number Publication date
US20220289781A1 (en) 2022-09-15
FI4025581T3 (fi) 2024-03-01
CN114341147A (zh) 2022-04-12
WO2021043402A1 (en) 2021-03-11
BR112022003645A2 (pt) 2022-05-24
JP2022551390A (ja) 2022-12-09
EP4025581A1 (en) 2022-07-13
IL291110A (en) 2022-07-01
CN114341147B (zh) 2024-05-07
JP7386972B2 (ja) 2023-11-27
EP4025581B1 (en) 2024-02-07
AU2019464913A1 (en) 2022-03-03
CA3153380A1 (en) 2021-03-11

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