NO323873B1 - Veksthormon sekretagoga - Google Patents
Veksthormon sekretagoga Download PDFInfo
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- NO323873B1 NO323873B1 NO20025893A NO20025893A NO323873B1 NO 323873 B1 NO323873 B1 NO 323873B1 NO 20025893 A NO20025893 A NO 20025893A NO 20025893 A NO20025893 A NO 20025893A NO 323873 B1 NO323873 B1 NO 323873B1
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0212—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -N-C-N-C(=0)-, e.g. retro-inverso peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
- C07K5/06034—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Physical Education & Sports Medicine (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Virology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Crystallography & Structural Chemistry (AREA)
- AIDS & HIV (AREA)
- Nutrition Science (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Oncology (AREA)
- Surgery (AREA)
- Communicable Diseases (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21132600P | 2000-06-13 | 2000-06-13 | |
| US23492800P | 2000-09-26 | 2000-09-26 | |
| PCT/EP2001/006717 WO2001096300A1 (en) | 2000-06-13 | 2001-06-13 | Growth hormone secretagogues |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20025893D0 NO20025893D0 (no) | 2002-12-09 |
| NO20025893L NO20025893L (no) | 2003-02-10 |
| NO323873B1 true NO323873B1 (no) | 2007-07-16 |
Family
ID=26906052
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20025893A NO323873B1 (no) | 2000-06-13 | 2002-12-09 | Veksthormon sekretagoga |
Country Status (30)
| Country | Link |
|---|---|
| US (2) | US6861409B2 (ja) |
| EP (1) | EP1289951B1 (ja) |
| JP (2) | JP3522265B2 (ja) |
| KR (1) | KR100825109B1 (ja) |
| CN (1) | CN1232507C (ja) |
| AR (1) | AR029941A1 (ja) |
| AT (3) | ATE302181T1 (ja) |
| AU (2) | AU6606601A (ja) |
| BG (3) | BG66130B1 (ja) |
| BR (1) | BRPI0111591B8 (ja) |
| CA (1) | CA2407659C (ja) |
| CY (2) | CY1107710T1 (ja) |
| CZ (2) | CZ305279B6 (ja) |
| DE (3) | DE60128494T2 (ja) |
| DK (3) | DK1289951T3 (ja) |
| ES (3) | ES2250416T3 (ja) |
| FR (1) | FR19C1044I2 (ja) |
| HK (1) | HK1054224A1 (ja) |
| HU (1) | HU229233B1 (ja) |
| IL (2) | IL153067A0 (ja) |
| MX (1) | MXPA02011899A (ja) |
| NL (1) | NL300999I2 (ja) |
| NO (1) | NO323873B1 (ja) |
| NZ (1) | NZ522280A (ja) |
| PL (1) | PL216676B1 (ja) |
| PT (2) | PT1344773E (ja) |
| RU (1) | RU2270198C2 (ja) |
| SK (1) | SK287169B6 (ja) |
| TW (2) | TWI305529B (ja) |
| WO (1) | WO2001096300A1 (ja) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE302181T1 (de) * | 2000-06-13 | 2005-09-15 | Zentaris Gmbh | Verbindungen zur stimulation der sekretion von wachstumshormonen |
| CU23157A1 (es) * | 2001-01-03 | 2006-07-18 | Ct Ingenieria Genetica Biotech | COMPOSICION FARMACéUTICA PARA EL TRATAMIENTO DEL DANO TISULAR DEBIDO A FALTA DE IRRIGACION SANGUINEA ARTERIAL |
| US7476653B2 (en) | 2003-06-18 | 2009-01-13 | Tranzyme Pharma, Inc. | Macrocyclic modulators of the ghrelin receptor |
| US7034050B2 (en) * | 2004-04-28 | 2006-04-25 | Romano Deghenghi | Pseudopeptides growth hormone secretagogues |
| JP4879265B2 (ja) * | 2005-07-22 | 2012-02-22 | イプセン ファルマ ソシエテ パール アクシオン サンプリフィエ | 成長ホルモン分泌促進薬 |
| EP1757290A1 (en) | 2005-08-16 | 2007-02-28 | Zentaris GmbH | Novel triazole derivatives as ghrelin analogue ligands of growth hormone secretagogue receptors |
| GB0603295D0 (en) | 2006-02-18 | 2006-03-29 | Ardana Bioscience Ltd | Methods and kits |
| CU23558A1 (es) | 2006-02-28 | 2010-07-20 | Ct Ingenieria Genetica Biotech | Compuestos análogos a los secretagogos peptidicos de la hormona de crecimiento |
| US7763707B2 (en) * | 2006-03-13 | 2010-07-27 | Liat Mintz | Use of ghrelin splice variant for treating cachexia and/or anorexia and/or anorexia-cachexia and/or malnutrition and/or lipodystrophy and/or muscle wasting and/or appetite-stimulation |
| BRPI0807046A2 (pt) | 2007-02-09 | 2015-05-26 | Tranzyme Pharma Inc | Composto, composição farmacêutica, métodos de tratar um distúrbio, uma doença cardiovascular e um paciente que sofre de motilidade gastrointestinal reduzida ou disfuncional e, kit. |
| EP2103602A1 (en) | 2008-03-17 | 2009-09-23 | AEterna Zentaris GmbH | Novel 1,2,4-triazole derivatives and process of manufacturing thereof |
| US8431642B2 (en) * | 2008-06-09 | 2013-04-30 | Exxonmobil Chemical Patents Inc. | Polyolefin adhesive compositions and articles made therefrom |
| EP2431035A1 (en) | 2010-09-16 | 2012-03-21 | Æterna Zentaris GmbH | Novel Triazole Derivatives with Improved Receptor Activity and Bioavailability Properties as Ghrelin Antagonists of Growth Hormone Secretagogue Receptors |
| US8747922B2 (en) | 2012-09-19 | 2014-06-10 | Quality Ip Holdings, Inc. | Methods and compositions for increasing sex steroids and growth hormones |
| US10300101B2 (en) | 2012-09-19 | 2019-05-28 | Quality IP Holdings, LLC | Methods and compositions for enhancing or maintaining fertility |
| US8747921B2 (en) | 2012-09-19 | 2014-06-10 | Quality Ip Holdings, Inc. | Methods for improving health in humans |
| US9198889B2 (en) | 2012-09-19 | 2015-12-01 | Quality IP Holdings, LLC | Methods for treating post-traumatic stress disorder |
| US8715752B2 (en) | 2012-09-20 | 2014-05-06 | Quality Ip Holdings, Inc. | Compositions for increasing human growth hormone levels |
| US9066953B2 (en) | 2012-09-20 | 2015-06-30 | Quality IP Holdings, LLC | Methods for increasing endurance and fat metabolism in humans |
| US8747923B2 (en) | 2012-09-20 | 2014-06-10 | Quality Ip Holdings, Inc. | Methods for improving health in canines |
| US10292957B2 (en) | 2012-09-20 | 2019-05-21 | Quality IP Holdings, LLC | Compositions and methods for treating fibromyalgia |
| BR112015009107A2 (pt) | 2012-10-24 | 2017-11-14 | Daiichi Sankyo Co Ltd | agente terapêutico para esclerose lateral amiotrófica, uso de um agonista do receptor do secretagogo do hormônio do crescimento ou um sal farmaceuticamente aceitável do mesmo, e, agonista do receptor do secretagogo do hormônio do crescimento ou sal farmaceuticamente aceitável do mesmo |
| CN105330720A (zh) * | 2014-06-06 | 2016-02-17 | 深圳翰宇药业股份有限公司 | 一种制备马昔瑞林的方法 |
| PL3939590T3 (pl) | 2015-09-21 | 2024-03-25 | Lumos Pharma, Inc. | Wykrywanie i leczenie niedoboru hormonu wzrostu |
| US10894072B2 (en) | 2017-02-13 | 2021-01-19 | IP Quality Holdings, LLC | Compositions and methods for treating fibromyalgia |
| US10288629B1 (en) | 2017-12-19 | 2019-05-14 | Aeterna Zentaris, Inc. | Method of assessing growth hormone deficiency in humans by a macimorelin containing composition |
| EP4185866A1 (en) | 2020-07-22 | 2023-05-31 | Aeterna Zentaris GmbH | A screening method for diagnosing growth hormone deficiency in pediatric patients by using macimorelin |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE68922602T2 (de) * | 1988-01-28 | 1995-12-07 | Polygen Holding Corp | Polypeptide mit hormonwachstumsbefreiender wirkung. |
| US5536814A (en) * | 1993-09-27 | 1996-07-16 | La Jolla Cancer Research Foundation | Integrin-binding peptides |
| AU684878B2 (en) | 1993-11-24 | 1998-01-08 | Merck & Co., Inc. | Compounds and the use thereof to promote the release of growth hormone(s) |
| US5798337A (en) * | 1994-11-16 | 1998-08-25 | Genentech, Inc. | Low molecular weight peptidomimetic growth hormone secretagogues |
| US6025471A (en) * | 1998-06-03 | 2000-02-15 | Deghenghi; Romano | Diazaspiro, azepino and azabicyclo therapeutic peptides |
| ATE302181T1 (de) * | 2000-06-13 | 2005-09-15 | Zentaris Gmbh | Verbindungen zur stimulation der sekretion von wachstumshormonen |
-
2001
- 2001-06-13 AT AT01943504T patent/ATE302181T1/de active
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- 2001-06-13 AU AU6606601A patent/AU6606601A/xx active Pending
- 2001-06-13 SK SK1756-2002A patent/SK287169B6/sk not_active IP Right Cessation
- 2001-06-13 AT AT05075086T patent/ATE362472T1/de active
- 2001-06-13 CZ CZ2011-585A patent/CZ305279B6/cs not_active IP Right Cessation
- 2001-06-13 ES ES01943504T patent/ES2250416T3/es not_active Expired - Lifetime
- 2001-06-13 AT AT03075950T patent/ATE370119T1/de active
- 2001-06-13 CA CA2407659A patent/CA2407659C/en not_active Expired - Lifetime
- 2001-06-13 EP EP01943504A patent/EP1289951B1/en not_active Expired - Lifetime
- 2001-06-13 AU AU2001266066A patent/AU2001266066B2/en not_active Expired
- 2001-06-13 WO PCT/EP2001/006717 patent/WO2001096300A1/en active IP Right Grant
- 2001-06-13 DE DE60128494T patent/DE60128494T2/de not_active Expired - Lifetime
- 2001-06-13 CN CNB018104916A patent/CN1232507C/zh not_active Expired - Lifetime
- 2001-06-13 PT PT03075950T patent/PT1344773E/pt unknown
- 2001-06-13 HU HU0302026A patent/HU229233B1/hu active IP Right Revival
- 2001-06-13 DK DK05075086T patent/DK1524272T3/da active
- 2001-06-13 MX MXPA02011899A patent/MXPA02011899A/es active IP Right Grant
- 2001-06-13 DE DE60112753T patent/DE60112753T2/de not_active Expired - Lifetime
- 2001-06-13 AR ARP010102827A patent/AR029941A1/es active IP Right Grant
- 2001-06-13 IL IL15306701A patent/IL153067A0/xx unknown
- 2001-06-13 CZ CZ20024095A patent/CZ303173B6/cs not_active IP Right Cessation
- 2001-06-13 KR KR1020027016614A patent/KR100825109B1/ko active IP Right Grant
- 2001-06-13 DE DE60130025T patent/DE60130025T2/de not_active Expired - Lifetime
- 2001-06-13 JP JP2002510444A patent/JP3522265B2/ja not_active Expired - Lifetime
- 2001-06-13 ES ES03075950T patent/ES2292900T3/es not_active Expired - Lifetime
- 2001-06-13 ES ES05075086T patent/ES2288724T3/es not_active Expired - Lifetime
- 2001-06-13 PL PL363081A patent/PL216676B1/pl unknown
- 2001-06-13 PT PT05075086T patent/PT1524272E/pt unknown
- 2001-06-13 DK DK03075950T patent/DK1344773T3/da active
- 2001-06-13 RU RU2002135312/04A patent/RU2270198C2/ru not_active IP Right Cessation
- 2001-06-13 BR BRPI0111591A patent/BRPI0111591B8/pt not_active IP Right Cessation
- 2001-06-13 US US09/880,498 patent/US6861409B2/en not_active Expired - Lifetime
- 2001-08-01 TW TW090114317A patent/TWI305529B/zh not_active IP Right Cessation
- 2001-08-01 TW TW097111056A patent/TW200831076A/zh unknown
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2002
- 2002-11-24 IL IL153067A patent/IL153067A/en active IP Right Grant
- 2002-12-09 NO NO20025893A patent/NO323873B1/no not_active IP Right Cessation
- 2002-12-12 BG BG107379A patent/BG66130B1/bg unknown
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2003
- 2003-06-02 JP JP2003156884A patent/JP4932132B2/ja not_active Expired - Lifetime
- 2003-08-27 HK HK03106131A patent/HK1054224A1/xx not_active IP Right Cessation
-
2004
- 2004-05-04 US US10/837,620 patent/US7297681B2/en not_active Expired - Lifetime
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2007
- 2007-08-07 CY CY20071101051T patent/CY1107710T1/el unknown
- 2007-11-08 CY CY20071101443T patent/CY1107793T1/el unknown
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2010
- 2010-07-21 BG BG10110708A patent/BG66216B1/bg unknown
- 2010-10-18 BG BG10110771A patent/BG66217B1/bg unknown
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2019
- 2019-07-05 NL NL300999C patent/NL300999I2/nl unknown
- 2019-07-08 FR FR19C1044C patent/FR19C1044I2/fr active Active
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Legal Events
| Date | Code | Title | Description |
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| CHAD | Change of the owner's name or address (par. 44 patent law, par. patentforskriften) |
Owner name: AETERNA ZENTARIS GMBH, DE |
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| MK1K | Patent expired |