NO2009011I1 - Kombinasjon omfattende aliskiren, som fri base eller som et farmasoytisk akseptabelt salt derav, og hydroklortiazid eller et farmasoytisk akseptabelt salt derav - Google Patents
Kombinasjon omfattende aliskiren, som fri base eller som et farmasoytisk akseptabelt salt derav, og hydroklortiazid eller et farmasoytisk akseptabelt salt deravInfo
- Publication number
- NO2009011I1 NO2009011I1 NO2009011C NO2009011C NO2009011I1 NO 2009011 I1 NO2009011 I1 NO 2009011I1 NO 2009011 C NO2009011 C NO 2009011C NO 2009011 C NO2009011 C NO 2009011C NO 2009011 I1 NO2009011 I1 NO 2009011I1
- Authority
- NO
- Norway
- Prior art keywords
- opt
- substd
- alkylene
- cooh
- mono
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
- C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C229/36—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
- C07C255/11—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound oxygen atoms bound to the same saturated acyclic carbon skeleton
- C07C255/13—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound oxygen atoms bound to the same saturated acyclic carbon skeleton containing cyano groups and etherified hydroxy groups bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/16—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/18—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by doubly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
- C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Heart & Thoracic Surgery (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Ophthalmology & Optometry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Reproductive Health (AREA)
- Anesthesiology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Furan Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Peptides Or Proteins (AREA)
- Pyrrole Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH116994 | 1994-04-18 |
Publications (2)
Publication Number | Publication Date |
---|---|
NO2009011I1 true NO2009011I1 (no) | 2009-06-02 |
NO2009011I2 NO2009011I2 (no) | 2010-11-22 |
Family
ID=4204102
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO19951441A NO310410B1 (no) | 1994-04-18 | 1995-04-12 | Nye <delta>-amino-<gamma>-hydroksy-<omega>-aryl- alkansyreamider, fremgangsmåte for fremstilling herav,farmasöytiske sammensetninger og mellomprodukter, samtforbindelser for anvendelse som terapeutikum |
NO2007011C NO2007011I1 (no) | 1994-04-18 | 2007-10-31 | Aliskiren eller farmasoytisk akseptable salter derav |
NO2009011C NO2009011I2 (no) | 1994-04-18 | 2009-05-18 | Kombinasjon omfattende aliskiren, som fri base eller som et farmasøytisk akseptabelt salt derav, og hydroklortiazid. |
NO2011020C NO2011020I1 (no) | 1994-04-18 | 2011-09-20 | Kombinasjon omfattende aliskiren, eller et farmasøytisk akseptabelt salt derav, og amlodipin, eller et farmasøytisk akseptabelt salt derav |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO19951441A NO310410B1 (no) | 1994-04-18 | 1995-04-12 | Nye <delta>-amino-<gamma>-hydroksy-<omega>-aryl- alkansyreamider, fremgangsmåte for fremstilling herav,farmasöytiske sammensetninger og mellomprodukter, samtforbindelser for anvendelse som terapeutikum |
NO2007011C NO2007011I1 (no) | 1994-04-18 | 2007-10-31 | Aliskiren eller farmasoytisk akseptable salter derav |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO2011020C NO2011020I1 (no) | 1994-04-18 | 2011-09-20 | Kombinasjon omfattende aliskiren, eller et farmasøytisk akseptabelt salt derav, og amlodipin, eller et farmasøytisk akseptabelt salt derav |
Country Status (27)
Country | Link |
---|---|
US (5) | US5559111A (no) |
EP (1) | EP0678503B1 (no) |
JP (1) | JP3240322B2 (no) |
KR (1) | KR100353779B1 (no) |
CN (2) | CN1266118C (no) |
AT (1) | ATE183997T1 (no) |
AU (1) | AU699616B2 (no) |
BR (1) | BR1100656A (no) |
CA (1) | CA2147056C (no) |
CY (4) | CY2208B1 (no) |
CZ (1) | CZ287935B6 (no) |
DE (4) | DE59506707D1 (no) |
DK (1) | DK0678503T3 (no) |
ES (1) | ES2137478T3 (no) |
FI (1) | FI118336B (no) |
GR (1) | GR3031997T3 (no) |
HK (1) | HK1070881A1 (no) |
HU (2) | HU226860B1 (no) |
IL (1) | IL113403A (no) |
LU (2) | LU91373I2 (no) |
MY (1) | MY119161A (no) |
NL (2) | NL300296I2 (no) |
NO (4) | NO310410B1 (no) |
NZ (1) | NZ270936A (no) |
RU (1) | RU95105970A (no) |
TW (2) | TW366341B (no) |
ZA (3) | ZA953050B (no) |
Families Citing this family (152)
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DE4408534A1 (de) * | 1994-03-14 | 1995-09-28 | Hoechst Ag | Substituierte N-Ethyl-Glycinderivate zur Herstellung von PNA und PNA-/DNA-Hybriden |
MY119161A (en) * | 1994-04-18 | 2005-04-30 | Novartis Ag | Delta-amino-gamma-hydroxy-omega-aryl-alkanoic acid amides with enzyme especially renin inhibiting activities |
EP0716077A1 (de) * | 1994-12-08 | 1996-06-12 | Ciba-Geigy Ag | Aromatisch substituierte Omega-Aminoalkansäureamide und Alkansäurediamide und ihre Verwendung als Renininhibitoren |
US6465650B1 (en) | 1995-03-13 | 2002-10-15 | Aventis Pharma Deutschland Gmbh | Substituted N-ethylglycine derivatives for preparing PNA and PNA/DNA hybrids |
ATE260904T1 (de) * | 1997-12-16 | 2004-03-15 | Warner Lambert Co | ((cyclo)alkyl substituierte)-.gamma.- aminobuttersäure derivate (=gaba analoga), deren herstellung und deren verwendung bei der behandlung von neurologischen erkrankungen |
US7354894B2 (en) * | 1998-08-18 | 2008-04-08 | The Regents Of The University Of California | Preventing airway mucus production by administration of EGF-R antagonists |
US6846799B1 (en) | 1998-08-18 | 2005-01-25 | The Regents Of The University Of California | Preventing airway mucus production by administration of EGF-R antagonists |
US6833460B2 (en) * | 1999-06-18 | 2004-12-21 | E. I. Du Pont De Nemours And Company | Preparation and use of gamma-butyrolactones as cross-linking agents |
US6423850B1 (en) | 1999-06-18 | 2002-07-23 | E.I. Du Pont De Nemours And Company | Preparation and use of gamma-butyrolactones as cross-linking agents |
AU5518500A (en) * | 1999-07-29 | 2001-02-19 | Speedel Pharma Ag | 2-alkyl-5-halogen-pent-4-ene carboxylic acids and their production |
EP1296912B1 (en) * | 2000-07-03 | 2006-01-25 | Speedel Pharma AG | Process for the preparation of (r)-2-alkyl-3-phenyl-1-propanols |
DE60138099D1 (de) * | 2000-07-05 | 2009-05-07 | Speedel Pharma Ag | Verfahren zur herstellung von substituierten octanoyl-amiden |
DE122007000077I2 (de) * | 2000-07-25 | 2008-08-21 | Speedel Pharma Ag Hirchgaessle | Verfahren zur herstellung von substituierten octanoyl-amiden |
US8168616B1 (en) * | 2000-11-17 | 2012-05-01 | Novartis Ag | Combination comprising a renin inhibitor and an angiotensin receptor inhibitor for hypertension |
ES2274847T3 (es) | 2000-12-14 | 2007-06-01 | Speedel Pharma Ag | Proceso para preparar ariloctanoil-amidas. |
JP3440082B2 (ja) | 2001-02-19 | 2003-08-25 | 科学技術振興事業団 | 電気自動車用インホイールモーター |
IL158586A0 (en) | 2001-05-15 | 2004-05-12 | Speedel Pharma Ag | Process for the preparation of substituted carboxylic acid esters by enzymatic hydrolysis |
WO2002100820A1 (en) * | 2001-06-11 | 2002-12-19 | Elan Pharmaceuticals, Inc. | Substituted aminoalcohols useful in treatment of alzheimer's disease |
EP1448190A2 (en) * | 2001-10-18 | 2004-08-25 | Novartis AG | Salts formed of an at1-receptor antagonist and a cardiovascular agent |
US20050101638A1 (en) * | 2002-11-08 | 2005-05-12 | Webb Randy L. | Combination of organic compounds |
RU2316318C2 (ru) * | 2002-05-17 | 2008-02-10 | Новартис Аг | Фармацевтическая композиция, включающая ингибитор ренина, блокатор кальциевых каналов и диуретик |
GB0212410D0 (en) * | 2002-05-29 | 2002-07-10 | Novartis Ag | Organic compounds |
AU2003238007A1 (en) * | 2002-06-11 | 2003-12-22 | Elan Pharmaceuticals, Inc. | Methods of treating alzheimer's disease using aryl alkanoic acid amides |
US20060089355A1 (en) * | 2002-06-11 | 2006-04-27 | Michel Maillard | Methods of treating alzheimer's disease using aromatically substituted w-amino-alkanoic acid amides and alkanoic acid diamides |
EP1539754A4 (en) * | 2002-08-23 | 2009-02-25 | Novartis Vaccines & Diagnostic | BENZIMIDAZOLE QUINOLINONES AND USES THEREOF |
US7049469B2 (en) | 2002-10-24 | 2006-05-23 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Process for preparing (R)-salbutamol |
BR0316629A (pt) | 2002-11-27 | 2005-10-11 | Elan Pharm Inc | Uréias e carbamatos substituìdos |
WO2004100871A2 (en) * | 2003-05-09 | 2004-11-25 | Pharmacia Corporation | Combination of an aldosterone receptor antagonist and a renin inhibitor |
WO2005019214A1 (en) * | 2003-08-25 | 2005-03-03 | Warner-Lambert Company Llc | Novel antimicrobial aryloxazolidinone compounds |
CN102260188A (zh) * | 2003-11-26 | 2011-11-30 | 诺瓦提斯公司 | 有机化合物 |
GB0327839D0 (en) | 2003-12-01 | 2003-12-31 | Novartis Ag | Organic compounds |
PE20050596A1 (es) * | 2003-12-19 | 2005-10-18 | Novartis Ag | Microemulsion que comprende un inhibidor renina |
BRPI0507030A (pt) * | 2004-01-22 | 2007-06-05 | Novartis Ag | combinação de compostos orgánicos |
PL1735270T3 (pl) * | 2004-01-23 | 2010-12-31 | Novartis Ag | Dwuaminoalkohole i ich zastosowanie jako inhibitorów reniny |
EP1756037B1 (en) * | 2004-01-23 | 2010-12-15 | Novartis AG | Amino alcohol derivatives and their activity as renin inhibitors |
PE20110121A1 (es) * | 2004-03-17 | 2011-02-28 | Novartis Ag | Composiciones farmaceuticas de aliskiren |
EP1729749A2 (en) | 2004-03-17 | 2006-12-13 | Novartis AG | Use of renin inhibitors in therapy |
US20070191487A1 (en) * | 2004-03-17 | 2007-08-16 | Rigassi-Dietrich Petra G | Galenic formulations of organic compounds |
WO2005090304A1 (en) * | 2004-03-19 | 2005-09-29 | Speedel Experimenta Ag | Organic compounds |
EP1712548A3 (en) * | 2004-03-19 | 2006-11-02 | Speedel Experimenta AG | 5-amino-4-hydroxy-7-(pyridinylmethyl)-alkanamide derivatives and related compounds as renin inhibitors for the treatment of hypertension |
WO2005095876A1 (en) | 2004-04-01 | 2005-10-13 | Cucumber Limited | Delivery and storage of goods |
GB0419361D0 (en) | 2004-08-31 | 2004-10-06 | Novartis Ag | Organic compounds |
KR20070101843A (ko) | 2004-10-08 | 2007-10-17 | 노파르티스 아게 | 확장기 기능장애 또는 확장기 심부전의 예방 또는 치료를위한 레닌 억제제의 용도 |
TW200631929A (en) | 2004-12-10 | 2006-09-16 | Speedel Experimenta Ag | ω -phenyloctanamides |
TW200633983A (en) * | 2004-12-10 | 2006-10-01 | Speedel Experimenta Ag | 5-Amino-4-hydroxy-2-isopropyl-7-[4-methoxy-3-(3-methoxypropoxy)benzyl]-8-methyl-nonanamides |
JP2008528691A (ja) * | 2005-02-02 | 2008-07-31 | ビテ ファーマシューティカルズ, インコーポレイテッド | レニン阻害剤としての1−アシルアミノ−2−ヒドロキシ−3−アミノ−ω−アリールアルカン |
TW200700358A (en) * | 2005-03-11 | 2007-01-01 | Speedel Experimenta Ag | Organic compounds |
CN101171230A (zh) * | 2005-03-11 | 2008-04-30 | 斯皮德尔实验股份公司 | 用作肾素抑制剂的杂环取代的链烷酰胺 |
ES2337826T3 (es) * | 2005-03-17 | 2010-04-29 | Basf Se | Metodo para la produccion de derivados opticamente activos de acido 3-fenilpropionico y productos de reaccion del mismo. |
GB0511686D0 (en) * | 2005-06-08 | 2005-07-13 | Novartis Ag | Organic compounds |
JP5123178B2 (ja) * | 2005-07-11 | 2013-01-16 | ノバルティス アーゲー | 新規ピロカテキン誘導体 |
US20070021413A1 (en) | 2005-07-20 | 2007-01-25 | Peter Herold | Diamino alcohols as therapeutic compounds |
US8063105B2 (en) | 2005-07-22 | 2011-11-22 | Merck Canada Inc. | Renin inhibitors |
EP1764098A1 (en) * | 2005-09-17 | 2007-03-21 | Speedel Experimenta AG | Diaminoalcohols derivatives for the treatment of Alzheimer, malaria, HIV |
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