RU95105970A - Новые дельта-амино-гамма-гидрокси-омега-арил-амиды алкан-карбоновой кислоты - Google Patents

Новые дельта-амино-гамма-гидрокси-омега-арил-амиды алкан-карбоновой кислоты

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Publication number
RU95105970A
RU95105970A RU95105970/04A RU95105970A RU95105970A RU 95105970 A RU95105970 A RU 95105970A RU 95105970/04 A RU95105970/04 A RU 95105970/04A RU 95105970 A RU95105970 A RU 95105970A RU 95105970 A RU95105970 A RU 95105970A
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Russia
Prior art keywords
rmeans
lower alkyl
hydroxy
substituted
cycloalkyl
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RU95105970/04A
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English (en)
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Гешке Рихард
Ch]
Клаус Майбаум Юрген
Шиллинг Вальтер
De]
Стутз Стэфан
Ригольер Паскаль
Ямагуши Ясушика
Клод Соген Ниссим
Херольд Петер
Fr]
Original Assignee
Циба - Гейге А.Г. (CH)
Циба - Гейге А.Г.
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=4204102&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RU95105970(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Циба - Гейге А.Г. (CH), Циба - Гейге А.Г. filed Critical Циба - Гейге А.Г. (CH)
Publication of RU95105970A publication Critical patent/RU95105970A/ru

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    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
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    • C07D307/26Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
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    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/34Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C229/36Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings with at least one amino group and one carboxyl group bound to the same carbon atom of the carbon skeleton
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    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
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    • C07C237/20Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
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    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
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    • C07C255/11Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound oxygen atoms bound to the same saturated acyclic carbon skeleton
    • C07C255/13Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound oxygen atoms bound to the same saturated acyclic carbon skeleton containing cyano groups and etherified hydroxy groups bound to the carbon skeleton
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    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Furan Compounds (AREA)
  • Peptides Or Proteins (AREA)
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Abstract

Дельта-амино-гамма- гидрокси-омега- арил-амиды алкан-карбоновой кислоты формулы I, приведенной в описании, и их соли обладают свойствами, сдерживающими активность ренина и могут быть использованы в качестве антигипертенсивных лекарственных биологически активных веществ.

Claims (1)

  1. Дельта-амино-гамма- гидрокси-омега- арил-амиды алкан-карбоновой кислоты формулы I, приведенной в описании, и их соли обладают свойствами, сдерживающими активность ренина и могут быть использованы в качестве антигипертенсивных лекарственных биологически активных веществ.
RU95105970/04A 1994-04-18 1995-04-13 Новые дельта-амино-гамма-гидрокси-омега-арил-амиды алкан-карбоновой кислоты RU95105970A (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1169/94-3 1994-04-18
CH116994 1994-04-18

Publications (1)

Publication Number Publication Date
RU95105970A true RU95105970A (ru) 1997-01-10

Family

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RU95105970/04A RU95105970A (ru) 1994-04-18 1995-04-13 Новые дельта-амино-гамма-гидрокси-омега-арил-амиды алкан-карбоновой кислоты

Country Status (27)

Country Link
US (5) US5559111A (ru)
EP (1) EP0678503B1 (ru)
JP (1) JP3240322B2 (ru)
KR (1) KR100353779B1 (ru)
CN (2) CN1153759C (ru)
AT (1) ATE183997T1 (ru)
AU (1) AU699616B2 (ru)
BR (1) BR1100656A (ru)
CA (1) CA2147056C (ru)
CY (4) CY2208B1 (ru)
CZ (1) CZ287935B6 (ru)
DE (4) DE59506707D1 (ru)
DK (1) DK0678503T3 (ru)
ES (1) ES2137478T3 (ru)
FI (1) FI118336B (ru)
GR (1) GR3031997T3 (ru)
HK (1) HK1070881A1 (ru)
HU (2) HUT71701A (ru)
IL (1) IL113403A (ru)
LU (2) LU91373I2 (ru)
MY (1) MY119161A (ru)
NL (2) NL300296I2 (ru)
NO (4) NO310410B1 (ru)
NZ (1) NZ270936A (ru)
RU (1) RU95105970A (ru)
TW (2) TW366341B (ru)
ZA (3) ZA953052B (ru)

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