NO20081970L - Sulfonamidderivat med PGD2-reseptorantagonistaktivitet - Google Patents
Sulfonamidderivat med PGD2-reseptorantagonistaktivitetInfo
- Publication number
- NO20081970L NO20081970L NO20081970A NO20081970A NO20081970L NO 20081970 L NO20081970 L NO 20081970L NO 20081970 A NO20081970 A NO 20081970A NO 20081970 A NO20081970 A NO 20081970A NO 20081970 L NO20081970 L NO 20081970L
- Authority
- NO
- Norway
- Prior art keywords
- ring
- receptor antagonist
- antagonist activity
- sulfonamide derivatives
- nitrogen
- Prior art date
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- C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
- C07D295/26—Sulfur atoms
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- A61K31/00—Medicinal preparations containing organic active ingredients
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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Abstract
Sulfonamidderivat som har DP-reseptorantagonist-aktivitet, farmasøytisk preparat og terapeutisk middel omfattende forbindelsen som en aktiv ingrediens, for behandling av allergisykdommer. Forbindelse med generell formel (II) hvor ring A er en aromatisk karbosyklisk ring, ring B er en nitrogenholdig ikke-aromatisk heterosyklisk ring, ring C er en aromatisk karbosyklisk ring, R1 er karboksy, R2 er halogenatom, R3 er eventuelt substituert alkyloksy, R4 er halogenatom, R5 er eventuelt substituert alkyl, M er sulfonyl, Y, L1 og L er enkeltbindinger, k er 0, 1, 2, 3 eller 4, n er 0, 1 eller 2, og q er 0, 1,2 eller 3, forutsatt at a) k er ikke 0 når ring B er en 6-leddet nitrogenholdig heterosyklisk ring som inneholder ett eller to nitrogen-atomer og ring C er en benzenring, og et farmasøytisk akseptabelt salt eller hydrat derav.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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JP2005280532 | 2005-09-27 | ||
JP2006062617 | 2006-03-08 | ||
PCT/JP2006/318917 WO2007037187A1 (ja) | 2005-09-27 | 2006-09-25 | Pgd2受容体アンタゴニスト活性を有するスルホンアミド誘導体 |
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NO20081970L true NO20081970L (no) | 2008-06-16 |
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NO20081970A NO20081970L (no) | 2005-09-27 | 2008-04-25 | Sulfonamidderivat med PGD2-reseptorantagonistaktivitet |
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EP (3) | EP2407459A1 (no) |
JP (3) | JP5114202B2 (no) |
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AU (1) | AU2006296004B2 (no) |
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RU (1) | RU2405770C2 (no) |
TW (2) | TWI325861B (no) |
WO (1) | WO2007037187A1 (no) |
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