NO20081087L - Fremgangsmater for fremstilling av sterilisert pankreatinpulver - Google Patents
Fremgangsmater for fremstilling av sterilisert pankreatinpulverInfo
- Publication number
- NO20081087L NO20081087L NO20081087A NO20081087A NO20081087L NO 20081087 L NO20081087 L NO 20081087L NO 20081087 A NO20081087 A NO 20081087A NO 20081087 A NO20081087 A NO 20081087A NO 20081087 L NO20081087 L NO 20081087L
- Authority
- NO
- Norway
- Prior art keywords
- methods
- pancreatin
- pancreatin powder
- preparing sterilized
- sterilized
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/94—Pancreatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/37—Digestive system
- A61K35/39—Pancreas; Islets of Langerhans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/54—Mixtures of enzymes or proenzymes covered by more than a single one of groups A61K38/44 - A61K38/46 or A61K38/51 - A61K38/53
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
- A61L2/04—Heat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nutrition Science (AREA)
- Cell Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Physiology (AREA)
- Virology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Det er beskrevet fremgangsmåte for fremstilling av pankreatin hvor konsentrasjonen av én eller flere biologiske forurensninger er redusert, slik som virus og/eller bakterier, hvor fremgangsmåten omfatter oppvarming av pankreatinet ved en temperatur på minst 85 °C ved et totalt innhold av oppløsningsmidler som er lavere enn 9 vekt%. Videre er det beskrevet et pankreatin som lar seg erholde ved hjelp av en slik fremgangsmåte.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US70381305P | 2005-07-29 | 2005-07-29 | |
EP05016533 | 2005-07-29 | ||
PCT/EP2006/064717 WO2007014896A1 (en) | 2005-07-29 | 2006-07-27 | Processes for the manufacture of sterilized pancreatin powder |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20081087L true NO20081087L (no) | 2008-04-28 |
NO340996B1 NO340996B1 (no) | 2017-07-31 |
Family
ID=35457614
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20081087A NO340996B1 (no) | 2005-07-29 | 2008-02-29 | Fremgangsmåter for fremstilling av pankreatin som er redusert i virus-forurensninger |
NO20171131A NO342419B1 (no) | 2005-07-29 | 2017-07-07 | Pankreatin som er redusert i virus-forurensninger, og farmasøytisk sammensetning derav |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20171131A NO342419B1 (no) | 2005-07-29 | 2017-07-07 | Pankreatin som er redusert i virus-forurensninger, og farmasøytisk sammensetning derav |
Country Status (18)
Country | Link |
---|---|
US (3) | US20070148151A1 (no) |
EP (2) | EP1913138B1 (no) |
JP (1) | JP5140586B2 (no) |
KR (1) | KR101555058B1 (no) |
CN (1) | CN101233229B (no) |
AU (1) | AU2006274835B2 (no) |
BR (1) | BRPI0614914A2 (no) |
CA (1) | CA2616943C (no) |
ES (2) | ES2635308T3 (no) |
HK (1) | HK1120288A1 (no) |
HU (2) | HUE031042T2 (no) |
IL (1) | IL189103A (no) |
MX (1) | MX2008000850A (no) |
NO (2) | NO340996B1 (no) |
PL (2) | PL2278002T3 (no) |
RU (1) | RU2413532C2 (no) |
UA (1) | UA93384C2 (no) |
WO (1) | WO2007014896A1 (no) |
Families Citing this family (49)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6632429B1 (en) | 1999-12-17 | 2003-10-14 | Joan M. Fallon | Methods for treating pervasive development disorders |
US20070053895A1 (en) * | 2000-08-14 | 2007-03-08 | Fallon Joan M | Method of treating and diagnosing parkinsons disease and related dysautonomic disorders |
IT1319655B1 (it) | 2000-11-15 | 2003-10-23 | Eurand Int | Microsfere di enzimi pancreatici con elevata stabilita' e relativometodo di preparazione. |
US8030002B2 (en) | 2000-11-16 | 2011-10-04 | Curemark Llc | Methods for diagnosing pervasive development disorders, dysautonomia and other neurological conditions |
US8100844B2 (en) * | 2002-04-25 | 2012-01-24 | Ultraflex Systems, Inc. | Ambulating ankle and knee joints with bidirectional dampening and assistance using elastomeric restraint |
PT1729797E (pt) | 2004-03-22 | 2008-12-17 | Solvay Pharm Gmbh | Composições farmacêuticas orais de produtos contendo lipase, em particular de pancreatina, contendo tensioactivos |
US20060198838A1 (en) * | 2004-09-28 | 2006-09-07 | Fallon Joan M | Combination enzyme for cystic fibrosis |
EP1913138B1 (en) | 2005-07-29 | 2016-08-24 | Abbott Laboratories GmbH | Processes for the manufacture of pancreatin powder with low virus content |
US9198871B2 (en) | 2005-08-15 | 2015-12-01 | Abbott Products Gmbh | Delayed release pancreatin compositions |
US11266607B2 (en) | 2005-08-15 | 2022-03-08 | AbbVie Pharmaceuticals GmbH | Process for the manufacture and use of pancreatin micropellet cores |
US20080058282A1 (en) | 2005-08-30 | 2008-03-06 | Fallon Joan M | Use of lactulose in the treatment of autism |
US20070116695A1 (en) * | 2005-09-21 | 2007-05-24 | Fallon Joan M | Pharmaceutical preparations for attention deficit disorder, attention deficit hyperactivity disorder and other associated disorders |
US10072256B2 (en) * | 2006-05-22 | 2018-09-11 | Abbott Products Gmbh | Process for separating and determining the viral load in a pancreatin sample |
SG186648A1 (en) | 2007-02-20 | 2013-01-30 | Aptalis Pharma Ltd | Stable digestive enzyme compositions |
US20090130063A1 (en) * | 2007-11-15 | 2009-05-21 | Solvay Pharmaceuticals Gmbh | Process for separating and determining the viral load in a pancreatin sample |
MX2010003707A (es) * | 2007-11-15 | 2010-04-21 | Solvay Pharm Gmbh | Nuevo proceso para separar y determinar la carga viral en una muestra de pancreatina. |
US10087493B2 (en) * | 2008-03-07 | 2018-10-02 | Aptalis Pharma Canada Ulc | Method for detecting infectious parvovirus in pharmaceutical preparations |
US8658163B2 (en) | 2008-03-13 | 2014-02-25 | Curemark Llc | Compositions and use thereof for treating symptoms of preeclampsia |
US8084025B2 (en) | 2008-04-18 | 2011-12-27 | Curemark Llc | Method for the treatment of the symptoms of drug and alcohol addiction |
US20090324730A1 (en) * | 2008-06-26 | 2009-12-31 | Fallon Joan M | Methods and compositions for the treatment of symptoms of complex regional pain syndrome |
US9320780B2 (en) * | 2008-06-26 | 2016-04-26 | Curemark Llc | Methods and compositions for the treatment of symptoms of Williams Syndrome |
WO2010002972A1 (en) * | 2008-07-01 | 2010-01-07 | Curemark, Llc | Methods and compositions for the treatment of symptoms of neurological and mental health disorders |
US10776453B2 (en) * | 2008-08-04 | 2020-09-15 | Galenagen, Llc | Systems and methods employing remote data gathering and monitoring for diagnosing, staging, and treatment of Parkinsons disease, movement and neurological disorders, and chronic pain |
EP2165717A1 (de) * | 2008-08-27 | 2010-03-24 | Nordmark Arzneimittel GmbH & Co.KG | Verfahren zur Verringerung der viralen und mikrobiellen Belastung feststoffhaltiger biologischer Extrakte |
US20100092447A1 (en) | 2008-10-03 | 2010-04-15 | Fallon Joan M | Methods and compositions for the treatment of symptoms of prion diseases |
DE202008014562U1 (de) | 2008-11-03 | 2009-02-26 | Nordmark Arzneimittel Gmbh & Co. Kg | Pankreatin |
ATE541591T1 (de) * | 2008-11-03 | 2012-02-15 | Nordmark Arzneimittel Gmbh & Co Kg | Verfahren zur verringerung der viralen und mikrobiellen belastung von pankreatin |
KR101694931B1 (ko) | 2009-01-06 | 2017-01-10 | 큐어론 엘엘씨 | 이. 콜라이에 의한 구강 감염의 치료 또는 예방을 위한 조성물 및 방법 |
KR20170005192A (ko) | 2009-01-06 | 2017-01-11 | 큐어론 엘엘씨 | 스타필로코쿠스 아우레우스 감염의 치료 또는 예방 및 표면 상의 스타필로코쿠스 아우레우스의 박멸 또는 감소를 위한 조성물 및 방법 |
US9056050B2 (en) | 2009-04-13 | 2015-06-16 | Curemark Llc | Enzyme delivery systems and methods of preparation and use |
US8784884B2 (en) | 2009-09-17 | 2014-07-22 | Stephen Perrett | Pancreatic enzyme compositions and methods for treating pancreatitis and pancreatic insufficiency |
US9511125B2 (en) | 2009-10-21 | 2016-12-06 | Curemark Llc | Methods and compositions for the treatment of influenza |
CN102884181A (zh) * | 2010-03-19 | 2013-01-16 | 加拿大阿普塔利斯制药公司 | 用于药用胰腺酶制剂中的病毒灭活的β-丙内酯 |
UA111726C2 (uk) | 2010-10-01 | 2016-06-10 | Апталіс Фарма Лімітед | Препарат панкреліпази низької сили з кишковорозчинним покриттям |
CN106310242B (zh) | 2011-04-21 | 2020-02-28 | 柯尔马克有限责任公司 | 用于治疗神经精神障碍的化合物 |
EP2741766B1 (en) | 2011-08-08 | 2015-10-07 | Aptalis Pharma Limited | Method for dissolution testing of solid compositions containing digestive enzymes |
JP5814094B2 (ja) * | 2011-11-30 | 2015-11-17 | ふたみ青果株式会社 | 遠赤外線ヒーターによる凍結乾燥方法とその装置 |
US10350278B2 (en) | 2012-05-30 | 2019-07-16 | Curemark, Llc | Methods of treating Celiac disease |
US10993996B2 (en) | 2013-08-09 | 2021-05-04 | Allergan Pharmaceuticals International Limited | Digestive enzyme composition suitable for enteral administration |
BR112016000658A2 (pt) | 2013-11-05 | 2018-03-20 | Allergan Pharmaceuticals International Limited | pancreatina de alta atividade, processo para a preparação de pancreatina de aa tendo atividade lipásica específica de pelo menos aproximadamente 120 usp iu/mg e método de tratamento de um paciente sujeito a uma condição patológica associada com a insuficiência enzimática pandreática |
CA2947998A1 (en) | 2014-06-19 | 2015-12-23 | Aptalis Pharma Ltd. | Methods for removing viral contaminants from pancreatic extracts |
CN107073084B (zh) * | 2014-11-05 | 2022-03-25 | 雅培制药股份有限公司 | 用于生产具有改善的安全特性的具有脂肪酶活性的组合物和适用于药物用途的组合物的方法 |
EP3298139B1 (en) | 2015-05-19 | 2021-09-15 | Scientific Protein Laboratories LLC | Method for reducing or inactivating viral and microbial content in the processes for the manufacture of pancreatin |
DE102015119006A1 (de) | 2015-11-05 | 2017-05-11 | Nordmark Arzneimittel Gmbh & Co. Kg | Verfahren zur Reduzierung der Belastung von Pankreatin mit Mikroorganismen |
WO2017172619A1 (en) | 2016-03-28 | 2017-10-05 | Abb Vie Inc. | Enzyme compositions with reduced viral and microbial contamination |
US11278603B2 (en) | 2016-03-28 | 2022-03-22 | Abbvie Inc. | Enzyme compositions with reduced viral and microbial contamination |
KR101813920B1 (ko) * | 2016-07-06 | 2018-01-04 | 넨시스(주) | 판크레아틴의 살균방법 및 이를 이용한 판크레아틴 제조방법 |
EP3688153A1 (en) * | 2017-09-27 | 2020-08-05 | Abbott Laboratories GmbH | Enzyme compositions with reduced viral and microbial contamination |
US11541009B2 (en) | 2020-09-10 | 2023-01-03 | Curemark, Llc | Methods of prophylaxis of coronavirus infection and treatment of coronaviruses |
Family Cites Families (181)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2189948A (en) | 1938-10-31 | 1940-02-13 | Griffith Laboratories | Sterilization of pancreatin |
US2503313A (en) | 1947-04-14 | 1950-04-11 | Levin Ezra | Production of dried, defatted enzymatic material |
US3324002A (en) * | 1962-09-17 | 1967-06-06 | Armour Pharma | Anti-inflammatory preparations containing proteolytic enzymes and adrenal glucocorticoids |
US3803305A (en) * | 1962-12-28 | 1974-04-09 | Rolland A Lab | Process for obtaining extracts from pancreas |
US3956483A (en) * | 1968-10-24 | 1976-05-11 | Wilson Pharmaceutical & Chemical Corporation | Preparing pancreatin |
DE2035739A1 (en) | 1970-07-18 | 1972-01-27 | Röhm FmbH, 6100 Darmstadt | Oral enzyme prepsn - consisting of granulate with gastric juices-resistant coating in tablet or capsule form |
US3991180A (en) * | 1972-03-06 | 1976-11-09 | Rohm And Haas Company | Stabilization of internally administered pancreatic lipase |
FR2183546B1 (no) * | 1972-05-10 | 1975-06-20 | Servier Lab | |
JPS4936886A (no) | 1972-08-15 | 1974-04-05 | ||
JPS5543723B2 (no) | 1972-08-24 | 1980-11-07 | ||
DE2410241A1 (de) | 1974-03-04 | 1975-09-18 | Christian Brunnengraeber Chem | Granulataehnliche darreichungsform fuer arzneimittel |
DE2512746C3 (de) * | 1975-03-22 | 1980-04-24 | Kali-Chemie Pharma Gmbh, 3000 Hannover | Verfahren zur Herstellung von keimarmem, faserfreiem Pankreatin |
US3986927A (en) * | 1975-04-28 | 1976-10-19 | Armour Pharmaceutical Company | Process for the purification and sterilization of acidophilic biologicals by extreme acidification at cold temperatures |
GB1509866A (en) * | 1975-06-10 | 1978-05-04 | Johnson & Johnson | Enteric coated digestive enzyme compositions |
GB1590432A (en) * | 1976-07-07 | 1981-06-03 | Novo Industri As | Process for the production of an enzyme granulate and the enzyme granuate thus produced |
GB1603640A (en) | 1977-07-20 | 1981-11-25 | Gist Brocades Nv | Enzyme particles |
JPS5535031A (en) | 1978-09-04 | 1980-03-11 | Shin Etsu Chem Co Ltd | Enteric coating composition |
US4259440A (en) | 1979-05-21 | 1981-03-31 | Miles Laboratories, Inc. | Hydrolysis and assay of triglycerides |
DE2923279C2 (de) * | 1979-06-08 | 1987-07-09 | Kali-Chemie Pharma Gmbh, 3000 Hannover | Verfahren zur Herstellung von Pankreatin-Pellets und diese enthaltende Arzneimittel |
JPS5855125B2 (ja) | 1980-03-10 | 1983-12-08 | 信越化学工業株式会社 | 固形薬剤用腸溶性コ−テイング剤組成物 |
JPS57171428A (en) * | 1981-04-13 | 1982-10-22 | Sankyo Co Ltd | Preparation of coated solid preparation |
US4495278A (en) | 1981-04-27 | 1985-01-22 | Baxter Travenol Laboratories, Inc. | Process for making novel blood clotting enzyme compositions |
US4456590B2 (en) * | 1981-11-02 | 1989-05-30 | Heat treatment of lyphilized blood clotting factor viii concentrate | |
JPS58148814A (ja) | 1982-03-01 | 1983-09-05 | Fujimoto Seiyaku Kk | 消化酵素軟カプセル剤 |
JPS58179492A (ja) | 1982-04-12 | 1983-10-20 | Dainichi Seika Kogyo Kk | 洗剤用酵素粒剤およびその製造方法 |
DE3377506D1 (en) | 1982-12-30 | 1988-09-01 | Nordmark Arzneimittel Gmbh | Process for obtaining pancreatin |
US4447412A (en) * | 1983-02-01 | 1984-05-08 | Bilton Gerald L | Enzyme-containing digestive aid compostions |
JPS59169491A (ja) | 1983-03-15 | 1984-09-25 | Duskin Franchise Co Ltd | 酵素の安定化法 |
IE55711B1 (en) | 1983-10-24 | 1990-12-19 | Bausch & Lomb | Improved method for enzymatic cleaning and disinfecting contact lenses |
US4490361A (en) * | 1983-12-02 | 1984-12-25 | Alpha Therapeutic Corporation | Virus inactivating heat treatment of plasma fractions |
JPS61162185A (ja) | 1985-01-09 | 1986-07-22 | Nagase Seikagaku Kogyo Kk | 顆粒状酵素製剤の製造方法 |
US4689297A (en) * | 1985-03-05 | 1987-08-25 | Miles Laboratories, Inc. | Dust free particulate enzyme formulation |
US4707287A (en) | 1985-06-28 | 1987-11-17 | The Procter & Gamble Company | Dry bleach stable enzyme composition |
JPH0622461B2 (ja) | 1985-07-31 | 1994-03-30 | キユーピー株式会社 | 水中油型乳化食品の製造方法 |
US4775536A (en) * | 1986-02-24 | 1988-10-04 | Bristol-Myers Company | Enteric coated tablet and process for making |
US5766912A (en) * | 1986-03-17 | 1998-06-16 | Novo Nordisk A/S | Humicola lipase produced in aspergillus |
DK122686D0 (da) | 1986-03-17 | 1986-03-17 | Novo Industri As | Fremstilling af proteiner |
US5536661A (en) * | 1987-03-10 | 1996-07-16 | Novo Nordisk A/S | Process for the production of protein products in aspergillus |
US5874558A (en) * | 1986-03-17 | 1999-02-23 | Novo Nordisk | Nucleic acid encoding a recombinant humicola sp. lipase |
GB2189698A (en) * | 1986-04-30 | 1987-11-04 | Haessle Ab | Coated omeprazole tablets |
EP0277532B1 (en) | 1986-05-21 | 1990-08-22 | Novo Nordisk A/S | Production of a granular enzyme product and its use in detergent compositions |
DE3642853A1 (de) | 1986-12-16 | 1988-06-23 | Ulrich Von Dr Ing Pidoll | Arzneimittel |
DK435587D0 (da) | 1987-08-21 | 1987-08-21 | Novo Industri As | Fremgangsmaade til fremstilling af et enzymholdigt granulat |
DK435687D0 (da) | 1987-08-21 | 1987-08-21 | Novo Industri As | Enzymholdigt granulat og fremgangsmaade til fremstilling deraf |
ATE125865T1 (de) | 1987-08-28 | 1995-08-15 | Novo Nordisk As | Rekombinante humicola-lipase und verfahren zur herstellung von rekombinanten humicola-lipasen. |
US5068110A (en) * | 1987-09-29 | 1991-11-26 | Warner-Lambert Company | Stabilization of enteric coated dosage form |
IL88961A (en) | 1988-01-29 | 1992-07-15 | Basf Ag | Stable mixtures containing oxidation-sensitive compounds |
EP0404806B1 (en) | 1988-03-14 | 1992-03-11 | Novo Nordisk A/S | Stabilized particulate composition |
DK78189D0 (da) | 1989-02-20 | 1989-02-20 | Novo Industri As | Enzymholdigt granulat og fremgangsmaade til fremstilling deraf |
DK78089D0 (da) | 1989-02-20 | 1989-02-20 | Novo Industri As | Detergentholdigt granulat og fremgangsmaade til fremstilling deraf |
US5219572A (en) * | 1989-03-17 | 1993-06-15 | Pitman-Moore, Inc. | Controlled release delivery device for macromolecular proteins |
DE69027187T2 (de) * | 1989-06-15 | 1996-10-31 | Rorer Int Overseas | Verfahren zur inaktivierung von viren in mit viren verunreinigten pharmazeutischen zusammensetzungen |
GB8915658D0 (en) | 1989-07-07 | 1989-08-23 | Unilever Plc | Enzymes,their production and use |
US5658871A (en) * | 1989-07-07 | 1997-08-19 | Lever Brothers Company, Division Of Conopco, Inc. | Microbial lipase muteins and detergent compositions comprising same |
WO1991006638A1 (en) | 1989-10-31 | 1991-05-16 | Genencor International, Inc. | Dust-free coated enzyme formulation |
KR100229754B1 (ko) | 1989-11-24 | 1999-11-15 | 샬러 한스, 하우스 한스 루돌프 | 판크레아틴구형입자, 이의 제조방법 및 이를 함유하는 약제학적 조성물 |
WO1991016060A1 (en) | 1990-04-16 | 1991-10-31 | Cryopharm Corporation | Method of inactivation of viral and bacterial blood contaminants |
US6187572B1 (en) * | 1990-04-16 | 2001-02-13 | Baxter International Inc. | Method of inactivation of viral and bacterial blood contaminants |
JP3110437B2 (ja) | 1990-05-17 | 2000-11-20 | 財団法人化学及血清療法研究所 | 流行性非a非b型肝炎ウイルス抗原ペプチドおよびこれをコードする核酸断片 |
DK173590D0 (da) * | 1990-06-06 | 1990-07-19 | Novo Nordisk As | Rekombinante terapeutiske lipaser |
JPH05508549A (ja) | 1990-08-03 | 1993-12-02 | バーテツクス・フアーマシユーチカルズ・インコーポレーテツド | 新規な酵素固定化形態としての架橋結合された結晶の使用 |
US5801022A (en) * | 1990-08-03 | 1998-09-01 | Vertex Pharmaceuticals, Incorporated | Method of producing a product with crosslinked crystals of thermolysin |
US5618710A (en) * | 1990-08-03 | 1997-04-08 | Vertex Pharmaceuticals, Inc. | Crosslinked enzyme crystals |
US5869438A (en) * | 1990-09-13 | 1999-02-09 | Novo Nordisk A/S | Lipase variants |
JP3055799B2 (ja) | 1990-11-21 | 2000-06-26 | 塩野義製薬株式会社 | パンクレアチン含有組成物 |
US5254283A (en) | 1991-01-17 | 1993-10-19 | Genencor International, Inc. | Isophthalic polymer coated particles |
EP1787532A3 (en) * | 1991-01-24 | 2010-03-31 | Martek Biosciences Corporation | Microbial oil mixtures and uses thereof |
DK13491D0 (da) | 1991-01-25 | 1991-01-25 | Novo Nordisk As | Anvendelse af et enzymholdigt granulat og fremgangsmaade til fremstilling af et forderstof i tabletform |
DE4203315A1 (de) | 1991-02-14 | 1992-08-20 | Kali Chemie Pharma Gmbh | Verfahren zur gewinnung von pankreatin |
US5489530A (en) * | 1991-07-01 | 1996-02-06 | Basf Aktiengesellschaft | Lipase from Pseudomonas and strain |
US5225202A (en) * | 1991-09-30 | 1993-07-06 | E. R. Squibb & Sons, Inc. | Enteric coated pharmaceutical compositions |
US5324649A (en) * | 1991-10-07 | 1994-06-28 | Genencor International, Inc. | Enzyme-containing granules coated with hydrolyzed polyvinyl alcohol or copolymer thereof |
US5879920A (en) * | 1991-10-07 | 1999-03-09 | Genencor International, Inc. | Coated enzyme-containing granule |
ATE210723T1 (de) | 1991-10-07 | 2001-12-15 | Genencor Int | Umhüllte enzym enthaltende körnchen |
WO1993007260A1 (en) | 1991-10-10 | 1993-04-15 | Genencor International, Inc. | Process for dust-free enzyme manufacture |
DE4200002A1 (de) | 1992-01-02 | 1993-07-08 | Rudolf V Dipl Chem Dr Noronha | Reinigungstablette fuer die zahnprothesen |
US5686238A (en) | 1992-02-10 | 1997-11-11 | Baxter International Inc. | Method and device for testing blood units for viral contamination |
ATE229344T1 (de) | 1992-03-24 | 2002-12-15 | United Cancer Res Inst | Impfstoff enthaltend lebendes virus |
US5302400A (en) * | 1992-06-22 | 1994-04-12 | Digestive Care Inc. | Preparation of gastric acid-resistant microspheres containing digestive enzymes and buffered-bile acids |
US5260074A (en) * | 1992-06-22 | 1993-11-09 | Digestive Care Inc. | Compositions of digestive enzymes and salts of bile acids and process for preparation thereof |
DE4227385A1 (de) | 1992-08-19 | 1994-02-24 | Kali Chemie Pharma Gmbh | Pankreatinmikropellets |
WO1994008603A1 (en) | 1992-10-16 | 1994-04-28 | Smithkline Beecham Corporation | Compositions |
JP3264027B2 (ja) * | 1993-02-24 | 2002-03-11 | ソニー株式会社 | 放電セル及びその製造方法 |
DK39693D0 (da) | 1993-04-02 | 1993-04-02 | Novo Nordisk As | Enzym |
DE4322229A1 (de) | 1993-07-05 | 1995-01-12 | Cognis Bio Umwelt | Umhüllte Enzymzubereitung für Wasch- und Reinigungsmittel |
NZ273329A (en) | 1993-09-15 | 1996-09-25 | Unilever Plc | Skin care preparation containing stratum corneum trypsin-like enzymes |
US6312704B1 (en) * | 1993-09-30 | 2001-11-06 | Gattefosse, S.A. | Orally administrable composition capable of providing enhanced bioavailability when ingested |
US6054136A (en) * | 1993-09-30 | 2000-04-25 | Gattefosse S.A. | Orally administrable composition capable of providing enhanced bioavailability when ingested |
FR2710535B1 (fr) | 1993-09-30 | 1995-11-24 | Gattefosse Ets Sa | Composition à usage pharmaceutique ou cosmétique apte à former une microémulsion. |
DE4344215A1 (de) * | 1993-12-23 | 1995-06-29 | Cognis Bio Umwelt | Silberkorrosionsschutzmittelhaltige Enzymzubereitung |
US5605793A (en) | 1994-02-17 | 1997-02-25 | Affymax Technologies N.V. | Methods for in vitro recombination |
JP2917799B2 (ja) * | 1994-03-11 | 1999-07-12 | 田辺製薬株式会社 | 消化管内適所放出型製剤 |
DE4422198C2 (de) | 1994-06-24 | 1997-08-28 | Audi Ag | Verfahren zum Steuern der elektrischen Beheizung eines Katalysators |
JP3355593B2 (ja) * | 1994-08-19 | 2002-12-09 | 信越化学工業株式会社 | 固形腸溶製剤の製造方法 |
EP0804532B1 (en) | 1994-11-18 | 2001-01-17 | Genencor International, Inc. | Coated enzyme granules |
JPH08143457A (ja) | 1994-11-21 | 1996-06-04 | Microbial Chem Res Found | 酵素阻害剤および高脂血症抑制剤 |
WO1996038527A1 (en) | 1995-05-29 | 1996-12-05 | Kao Corporation | Enzyme-containing granulated substance and preparation process thereof |
AU6221496A (en) * | 1995-05-31 | 1996-12-18 | Simon Lodewijk Scharpe | Composition to improve digestibility and utilisation of nutr ients |
JPH09125096A (ja) | 1995-10-30 | 1997-05-13 | Koei Sangyo:Kk | 液状天然油脂洗剤 |
AU1200997A (en) | 1995-12-22 | 1997-07-17 | Helix Biotechnology Ltd | Thermostable proteolytic enzyme from thermoactinomyces thalpophilus thm1 |
ID18663A (id) * | 1996-04-12 | 1998-04-30 | Novartis Ag | Komposisi farmasi berlapis enterik |
CN1135265C (zh) | 1996-04-12 | 2004-01-21 | 诺沃奇梅兹有限公司 | 含酶颗粒及其生产方法 |
DE69737828T2 (de) * | 1996-04-29 | 2008-03-06 | Novozymes A/S | Flüssige, nichtwässrige enzyme enthaltende zusammensetzungen |
US6632648B1 (en) | 1996-05-14 | 2003-10-14 | Elan Drug Delivery Limited | Methods of terminal sterilization of fibrinogen |
US5750104A (en) * | 1996-05-29 | 1998-05-12 | Digestive Care Inc. | High buffer-containing enteric coating digestive enzyme bile acid compositions and method of treating digestive disorders therewith |
GB9613858D0 (en) | 1996-07-02 | 1996-09-04 | Cortecs Ltd | Hydrophobic preparations |
DE19724845A1 (de) | 1996-08-28 | 1998-03-05 | Solvay Pharm Gmbh | Verwendung von komplexen Lipiden als stabilisierende Zusätze zu pharmazeutischen Zubereitungen von Verdauungsenzymgemischen |
GB9624927D0 (en) * | 1996-11-29 | 1997-01-15 | Oxford Glycosciences Uk Ltd | Gels and their use |
US5861291A (en) | 1997-02-24 | 1999-01-19 | Biozymes Inc. | Method for producing pancreatin which contains low amounts of residual organic solvent and product thereof |
US6140475A (en) * | 1997-04-11 | 2000-10-31 | Altus Biologics Inc. | Controlled dissolution crosslinked protein crystals |
AUPO693397A0 (en) | 1997-05-22 | 1997-06-12 | Betatene Limited | Carotenoid formulation |
NZ330940A (en) | 1997-07-24 | 2000-02-28 | F | Production of consensus phytases from fungal origin using computer programmes |
ES2137862B1 (es) | 1997-07-31 | 2000-09-16 | Intexim S A | Preparacion farmaceutica oral que comprende un compuesto de actividad antiulcerosa y procedimiento para su obtencion. |
JP3611456B2 (ja) * | 1997-09-30 | 2005-01-19 | 日研化学株式会社 | テオフィリン徐放性錠剤 |
KR100387245B1 (ko) | 1997-10-17 | 2003-08-19 | 일양약품주식회사 | 유산균의안정화를위한미세장용성코팅과립 |
AU2155899A (en) | 1997-11-28 | 1999-06-16 | Innogenetics N.V. | Synthetic peptides containing citrulline recognized by rheumatoid arthritis sera as tools for diagnosis and treatment |
KR19990072826A (ko) | 1998-02-26 | 1999-09-27 | 우재영 | 판크레아틴장용코팅과립의제조방법 |
FR2775597B1 (fr) | 1998-03-04 | 2001-04-20 | Gattefosse Ets Sa | Pellet administrable par voie orale apte a ameliorer la biodisponibilite de la substance active, procede de fabrication |
US20030021844A1 (en) | 1998-03-04 | 2003-01-30 | Philippe Barthelemy | Immediate-release oral pellet comprising polyglycolysed glycerides, and manufacturing process |
ATE308293T1 (de) * | 1998-03-09 | 2005-11-15 | Ista Pharmaceuticals Inc | Verwendung von glyceraldehyde als hornhaut härtungsmitteln |
UA69413C2 (uk) * | 1998-05-22 | 2004-09-15 | Брістол-Майерс Сквібб Компані | Фармацевтична композиція, яка містить серцевину та ентеросолюбільну оболонку, фармацевтична композиція у вигляді сфероїдальних гранул, спосіб одержання сфероїдальних гранул та спосіб одержання фармацевтичної композиції |
DE29824797U1 (de) | 1998-05-22 | 2002-08-22 | Bristol-Myers Squibb Co., Princeton, N.J. | Magensaftresistent überzogene Arzneimittel |
US7122207B2 (en) * | 1998-05-22 | 2006-10-17 | Bristol-Myers Squibb Company | High drug load acid labile pharmaceutical composition |
US6268329B1 (en) * | 1998-06-30 | 2001-07-31 | Nouozymes A/S | Enzyme containing granule |
AU4499299A (en) | 1998-06-30 | 2000-01-24 | Novozymes A/S | A new improved enzyme containing granule |
DE19848849A1 (de) | 1998-10-22 | 2000-04-27 | Knoll Ag | Verfahren zur Herstellung von festen, sphärischen Formen, enthaltend eine biologisch aktive Substanz |
DE19856415C2 (de) | 1998-12-08 | 2001-06-07 | Thomas Fenner | Verfahren zur Reinigung bzw. Isolierung viraler Nukleinsäuren |
US6267985B1 (en) * | 1999-06-30 | 2001-07-31 | Lipocine Inc. | Clear oil-containing pharmaceutical compositions |
US6248363B1 (en) | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
US20030104048A1 (en) * | 1999-02-26 | 2003-06-05 | Lipocine, Inc. | Pharmaceutical dosage forms for highly hydrophilic materials |
SK284677B6 (sk) * | 1999-03-17 | 2005-09-08 | Solvay Pharmaceuticals Gmbh | Farmaceutický prípravok na liečbu diabetu a spôsob jeho prípravy |
WO2000073429A1 (fr) | 1999-05-27 | 2000-12-07 | Amano Enzyme Inc. | Liqueur enzymatique et procede de production correspondant, preparation enzymatique, preparations de proteases et bacteries produisant des proteases |
EP1889904A3 (en) | 1999-10-01 | 2008-07-09 | Novozymes A/S | Enzyme granulate |
DE60008497T2 (de) | 1999-10-12 | 2004-12-02 | Daiichi Suntory Pharma Co., Ltd. | Arzneimittel zur oralen verabreichung |
DK1225897T3 (da) * | 1999-11-01 | 2005-01-10 | John Rhodes | Sammensætning til behandling af obstipation og colon irritabile |
US20030180352A1 (en) * | 1999-11-23 | 2003-09-25 | Patel Mahesh V. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
DK1250057T3 (da) * | 1999-12-30 | 2006-02-20 | Kemin Ind Inc | Fremgangsmåde til forbedring af aktiviteten af enzymer |
BR0108164B1 (pt) | 2000-02-08 | 2014-06-17 | Dsm Ip Assets Bv | Uso de pelo menos uma protease estável em ácido, processo para melhorar o valor nutritivo de um alimento para animal, aditivo de alimento para animal, composição de alimento para animal, e, processo para tratar proteínas vegetais para uso em alimento para animal. |
US20010046493A1 (en) * | 2000-02-24 | 2001-11-29 | Alex Margolin | Lipase-containing composition and methods of use thereof |
KR20010100194A (ko) | 2000-03-13 | 2001-11-14 | 박호군 | 여러 가지 물질의 가용화용 조성물과 제형 및 그들의제조방법 |
DE10026698A1 (de) * | 2000-05-30 | 2001-12-06 | Basf Ag | Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung |
US20020146451A1 (en) * | 2000-07-15 | 2002-10-10 | Sharma Virender K. | Method for the administration of acid-labile drugs |
CN1336434A (zh) * | 2000-08-01 | 2002-02-20 | 上海惠海生化制品厂 | 胰激肽原酶的制备及其亲和层析纯化方法 |
WO2002020746A1 (en) | 2000-09-08 | 2002-03-14 | Novozymes A/S | Lubricated granules |
DE60119947T2 (de) | 2000-10-02 | 2007-01-04 | Novozymes A/S | Einen wirkstoff enthaltende, beschichtete teilchen |
IL155515A0 (en) * | 2000-11-02 | 2003-11-23 | Cilian Ag | Use of enzymes obtained from ciliates as medicaments for promoting digestion |
IT1319655B1 (it) | 2000-11-15 | 2003-10-23 | Eurand Int | Microsfere di enzimi pancreatici con elevata stabilita' e relativometodo di preparazione. |
AR032392A1 (es) | 2001-01-19 | 2003-11-05 | Solvay Pharm Gmbh | Mezcla de enzimas, preparado farmaceutico y utilizacion de dicho preparado. |
US6692771B2 (en) * | 2001-02-23 | 2004-02-17 | Cima Labs Inc. | Emulsions as solid dosage forms for oral administration |
US6676933B2 (en) * | 2001-05-23 | 2004-01-13 | Osmotica Corp. | Pharmaceutical composition containing mosapride and pancreatin |
EP1279402B1 (en) | 2001-07-26 | 2006-11-29 | Ethypharm | Coated granules of allylamine-or benzylamine-anti-mycotics, process for preparation thereof and orodispersible tablets containing said coated granules |
FR2827770B1 (fr) * | 2001-07-27 | 2005-08-19 | Gattefosse Ets Sa | Composition pharmaceutique a usage oral comprenant un principe actif susceptible de subir un important effet de premier passage intestinal |
US6749851B2 (en) * | 2001-08-31 | 2004-06-15 | Clearant, Inc. | Methods for sterilizing preparations of digestive enzymes |
US6783968B2 (en) * | 2001-09-24 | 2004-08-31 | Clearant, Inc. | Methods for sterilizing preparations of glycosidases |
BR0214679A (pt) | 2001-12-03 | 2004-12-14 | Novacea Inc | Composições farmacêuticas compreendendo compostos a base de vitamina d ativa |
WO2003055967A1 (en) | 2001-12-21 | 2003-07-10 | Novozymes A/S | Salt coatings |
US20040009953A1 (en) * | 2002-01-10 | 2004-01-15 | Comper Wayne D. | Antimicrobial charged polymers that exhibit resistance to lysosomal degradation during kidney filtration and renal passage, compositions and method of use thereof |
EP1490485B1 (en) | 2002-03-27 | 2015-03-04 | Novozymes A/S | Granules with filamentous coatings |
GB0216002D0 (en) * | 2002-07-10 | 2002-08-21 | Nat Blood Authority | Process and composition |
US20040161423A1 (en) * | 2002-07-18 | 2004-08-19 | Sanjeev Kumar (Mendiratta) | Polymer modified anti-angiogenic serpins |
BRPI0407108A (pt) | 2003-02-06 | 2006-01-24 | Novozymes As | Método para produzir uma imunoglobulina funcional humana |
US20040213847A1 (en) * | 2003-04-23 | 2004-10-28 | Matharu Amol Singh | Delayed release pharmaceutical compositions containing proton pump inhibitors |
AU2004260961B2 (en) | 2003-07-29 | 2010-05-20 | Abbott Laboratories Gmbh | Analytical method for pancreatin and comparable compositions |
CA2553731A1 (en) | 2004-01-21 | 2005-08-04 | Novozymes A/S | Production of a monoclonal antibody in a heterokaryon fungus or in a fungal host cell |
PT1729797E (pt) * | 2004-03-22 | 2008-12-17 | Solvay Pharm Gmbh | Composições farmacêuticas orais de produtos contendo lipase, em particular de pancreatina, contendo tensioactivos |
JP4936885B2 (ja) | 2004-04-23 | 2012-05-23 | 出光興産株式会社 | マグネシウム化合物、オレフィン重合用触媒及びオレフィン重合体の製造方法 |
ITMI20040891A1 (it) | 2004-05-04 | 2004-08-04 | Ibsa Inst Biochimique Sa | Nuovo metodo per la partizione ed inattivazione di contaminanti virali e prionici |
EP1809320B1 (en) | 2004-10-14 | 2010-07-21 | Altus Pharmaceuticals Inc. | Compositions containing lipase; protease and amylase for treating pancreatic insufficiency |
AR053634A1 (es) | 2005-06-24 | 2007-05-09 | Novozymes As | Lipasas para uso farmaceutico |
EP1913138B1 (en) | 2005-07-29 | 2016-08-24 | Abbott Laboratories GmbH | Processes for the manufacture of pancreatin powder with low virus content |
US7951384B2 (en) | 2005-08-05 | 2011-05-31 | University Of Massachusetts | Virus-like particles as vaccines for paramyxovirus |
CA2619477C (en) | 2005-08-15 | 2015-05-26 | Solvay Pharmaceuticals Gmbh | Pancreatin micropellet cores suitable for enteric coating |
US9198871B2 (en) * | 2005-08-15 | 2015-12-01 | Abbott Products Gmbh | Delayed release pancreatin compositions |
US11266607B2 (en) * | 2005-08-15 | 2022-03-08 | AbbVie Pharmaceuticals GmbH | Process for the manufacture and use of pancreatin micropellet cores |
SI1931316T2 (sl) | 2005-08-15 | 2017-05-31 | Abbott Laboratories Gmbh | Farmacevtski sestavki z nadzorovanim sproščanjem za kislinsko labilna zdravila |
US10072256B2 (en) * | 2006-05-22 | 2018-09-11 | Abbott Products Gmbh | Process for separating and determining the viral load in a pancreatin sample |
WO2007135125A1 (en) | 2006-05-22 | 2007-11-29 | Solvay Pharmaceuticals Gmbh | Process for separating and determining the viral load in a pancreatin sample |
EP2455461B1 (en) | 2006-12-21 | 2016-03-16 | Novozymes A/S | Lipase variants for pharmaceutical use |
SG186648A1 (en) | 2007-02-20 | 2013-01-30 | Aptalis Pharma Ltd | Stable digestive enzyme compositions |
US20090130063A1 (en) * | 2007-11-15 | 2009-05-21 | Solvay Pharmaceuticals Gmbh | Process for separating and determining the viral load in a pancreatin sample |
US10087493B2 (en) * | 2008-03-07 | 2018-10-02 | Aptalis Pharma Canada Ulc | Method for detecting infectious parvovirus in pharmaceutical preparations |
-
2006
- 2006-07-27 EP EP06778012.2A patent/EP1913138B1/en not_active Revoked
- 2006-07-27 HU HUE06778012A patent/HUE031042T2/en unknown
- 2006-07-27 MX MX2008000850A patent/MX2008000850A/es active IP Right Grant
- 2006-07-27 EP EP10178590.5A patent/EP2278002B1/en not_active Revoked
- 2006-07-27 RU RU2008107261/15A patent/RU2413532C2/ru active
- 2006-07-27 CN CN2006800277018A patent/CN101233229B/zh active Active
- 2006-07-27 US US11/460,330 patent/US20070148151A1/en not_active Abandoned
- 2006-07-27 JP JP2008523364A patent/JP5140586B2/ja active Active
- 2006-07-27 BR BRPI0614914-6A patent/BRPI0614914A2/pt not_active Application Discontinuation
- 2006-07-27 ES ES10178590.5T patent/ES2635308T3/es active Active
- 2006-07-27 UA UAA200802536A patent/UA93384C2/ru unknown
- 2006-07-27 CA CA2616943A patent/CA2616943C/en active Active
- 2006-07-27 AU AU2006274835A patent/AU2006274835B2/en active Active
- 2006-07-27 HU HUE10178590A patent/HUE034739T2/en unknown
- 2006-07-27 WO PCT/EP2006/064717 patent/WO2007014896A1/en active Application Filing
- 2006-07-27 KR KR1020087004969A patent/KR101555058B1/ko active IP Right Grant
- 2006-07-27 ES ES06778012.2T patent/ES2597381T3/es active Active
- 2006-07-27 PL PL10178590T patent/PL2278002T3/pl unknown
- 2006-07-27 PL PL06778012T patent/PL1913138T3/pl unknown
-
2008
- 2008-01-29 IL IL189103A patent/IL189103A/en active IP Right Grant
- 2008-02-29 NO NO20081087A patent/NO340996B1/no unknown
- 2008-09-30 HK HK08110876.0A patent/HK1120288A1/xx unknown
-
2016
- 2016-07-20 US US15/214,973 patent/US10704037B2/en active Active
-
2017
- 2017-07-07 NO NO20171131A patent/NO342419B1/no unknown
-
2020
- 2020-06-04 US US16/893,036 patent/US20200299669A1/en not_active Abandoned
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO20081087L (no) | Fremgangsmater for fremstilling av sterilisert pankreatinpulver | |
Fu et al. | Induction of Escherichia coli O157: H7 into a viable but non‐culturable state by high temperature and its resuscitation | |
SE0701440L (sv) | Förfarande för modifiering av polyfenolinnehållande växtmaterial och medicinska användningar av de modifierade polyfenolinnehållande växtmaterialen | |
EP1831353A4 (en) | NON-TUMORING MDCK CELL LINES FOR VIRUSING | |
NO20062247L (no) | Melsammensetning med okt totalmengde kostfiber, fremgangsmate for fremstilling og anvendelser derav | |
WO2008157497A3 (en) | Method of treating tissue | |
MY151119A (en) | Duck embryonic derived stem cell lines for the production of viral vaccines | |
ATE541591T1 (de) | Verfahren zur verringerung der viralen und mikrobiellen belastung von pankreatin | |
NZ611994A (en) | Viral inactivation using improved solvent-detergent method | |
BRPI0917104A8 (pt) | Uso de sulfoximinas para intensificar a resistência de plantas a fatores abióticos de estresse de deficência de oxigênio, solução nutriente, e seu uso | |
WO2010047830A3 (en) | Agents for hcv treatment | |
Donati et al. | Stilbene biosynthesis and gene expression in response to methyl jasmonate and continuous light treatment in Vitis vinifera cv. Malvasia del Lazio and Vitis rupestris Du Lot cell cultures | |
NO20082862L (no) | Nye alkylfosfolipidderivater med redusert cytotoksisitet og anvendelse derav | |
Lal et al. | Identification of a Novel Geminivirus in Fraxinus rhynchophylla in Korea | |
ATE397620T1 (de) | Aufreinigungsverfahren, das eine mikrofiltration bei erhöhten temperaturen beinhaltet | |
BRPI0823057A2 (pt) | Planta da espécie cucumis melo, parte de planta, método para obter uma planta resistente a cvyv da espécie cucumis melo, planta resistente ao vírus do amarelecimento das nervuras do pepino (cvyv) da espécie cucumis melo, uso de pelo menos um marcador molecular, e resistência ao vírus do amarelecimento das nervuras do pedido (cvyv) conferindo locos de caracteres quantitativos (qtl), ou uma parte da mesma conferindo resistência a cvyv. | |
WO2009132856A3 (de) | Methode und vorrichtung zur behandlung von eiern mit schale | |
WO2008136861A3 (en) | Inactivated and dried biological preparations | |
BR0308736A (pt) | Células de pulmão de rato cotton para cultura de vìrus | |
Stolarzewicz et al. | Plant and microbial sources of antioxidants | |
DK1981549T3 (da) | Fremgangsmåde til viral inaktivering ved tör opvarmning | |
Mahajan et al. | A wound inducible chalcone synthase gene from Dysoxylum gotadhora (DbCHS) regulates flavonoid biosynthesis | |
WO2014001476A3 (en) | Non-destructive heat treatment of trees to stop disease progression | |
MX2016016010A (es) | Metodo y estuche diagnostico para la deteccion de virus fitopatogenos. | |
Muhammad et al. | Use of silver nanoparticles to suppress Cucumber mosaic virus (CMV) in ginger (Zingiber officinale Roscoe) and turmeric (Curcuma longa L.) |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
CHAD | Change of the owner's name or address (par. 44 patent law, par. patentforskriften) |
Owner name: ABBOTT LABORATORIES GMBH, DE |