ATE308293T1 - Verwendung von glyceraldehyde als hornhaut härtungsmitteln - Google Patents

Verwendung von glyceraldehyde als hornhaut härtungsmitteln

Info

Publication number
ATE308293T1
ATE308293T1 AT99912347T AT99912347T ATE308293T1 AT E308293 T1 ATE308293 T1 AT E308293T1 AT 99912347 T AT99912347 T AT 99912347T AT 99912347 T AT99912347 T AT 99912347T AT E308293 T1 ATE308293 T1 AT E308293T1
Authority
AT
Austria
Prior art keywords
eye
cornea
emmetropic
glyceral
dehyde
Prior art date
Application number
AT99912347T
Other languages
English (en)
Inventor
Hampar Karageozian
John Y Park
Vicken Karageozian
Phillip Baker
Anthony Nesburn
Original Assignee
Ista Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ista Pharmaceuticals Inc filed Critical Ista Pharmaceuticals Inc
Application granted granted Critical
Publication of ATE308293T1 publication Critical patent/ATE308293T1/de

Links

Classifications

    • GPHYSICS
    • G02OPTICS
    • G02CSPECTACLES; SUNGLASSES OR GOGGLES INSOFAR AS THEY HAVE THE SAME FEATURES AS SPECTACLES; CONTACT LENSES
    • G02C7/00Optical parts
    • G02C7/02Lenses; Lens systems ; Methods of designing lenses
    • G02C7/04Contact lenses for the eyes
    • G02C7/047Contact lens fitting; Contact lenses for orthokeratology; Contact lenses for specially shaped corneae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007Methods or devices for eye surgery
    • A61F9/013Instruments for compensation of ocular refraction ; Instruments for use in cornea removal, for reshaping or performing incisions in the cornea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/10Ophthalmic agents for accommodation disorders, e.g. myopia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/14Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/147Implants to be inserted in the stroma for refractive correction, e.g. ring-like implants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007Methods or devices for eye surgery
    • A61F9/008Methods or devices for eye surgery using laser
    • A61F2009/00853Laser thermal keratoplasty or radial keratotomy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007Methods or devices for eye surgery
    • A61F9/008Methods or devices for eye surgery using laser
    • A61F2009/00861Methods or devices for eye surgery using laser adapted for treatment at a particular location
    • A61F2009/00872Cornea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007Methods or devices for eye surgery
    • A61F9/008Methods or devices for eye surgery using laser
    • A61F2009/00885Methods or devices for eye surgery using laser for treating a particular disease
    • A61F2009/00887Cataract
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/16Materials or treatment for tissue regeneration for reconstruction of eye parts, e.g. intraocular lens, cornea

Landscapes

  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Surgery (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Transplantation (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Cardiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT99912347T 1998-03-09 1999-03-09 Verwendung von glyceraldehyde als hornhaut härtungsmitteln ATE308293T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7733998P 1998-03-09 1998-03-09
PCT/US1999/005135 WO1999045869A1 (en) 1998-03-09 1999-03-09 Use of corneal hardening agents in enzyme orthokeratology

Publications (1)

Publication Number Publication Date
ATE308293T1 true ATE308293T1 (de) 2005-11-15

Family

ID=22137478

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99912347T ATE308293T1 (de) 1998-03-09 1999-03-09 Verwendung von glyceraldehyde als hornhaut härtungsmitteln

Country Status (11)

Country Link
US (2) US6537545B1 (de)
EP (1) EP1061873B1 (de)
JP (1) JP2002506013A (de)
KR (1) KR20010041806A (de)
CN (1) CN1200698C (de)
AT (1) ATE308293T1 (de)
AU (1) AU758862B2 (de)
BR (1) BR9908692A (de)
CA (1) CA2323199A1 (de)
DE (1) DE69928087D1 (de)
WO (1) WO1999045869A1 (de)

Families Citing this family (112)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6493570B1 (en) * 1998-11-02 2002-12-10 Photogen, Inc. Method for improved imaging and photodynamic therapy
BR9908692A (pt) * 1998-03-09 2001-12-04 Ista Pharmaceuticals Inc Uso de agentes de enrijecimento corneal emortocerotologia enzimática
US8470296B2 (en) 1998-12-21 2013-06-25 Provectus Pharmatech, Inc. Intracorporeal medicaments for high energy phototherapeutic treatment of disease
US20020001567A1 (en) * 1998-12-21 2002-01-03 Photogen, Inc. Intracorporeal medicaments for high energy phototherapeutic treatment of disease
US6946440B1 (en) * 1999-09-15 2005-09-20 Dewoolfson Bruce H Composition for stabilizing corneal tissue during or after orthokeratology lens wear
US6652095B2 (en) * 2000-11-17 2003-11-25 Hsiao-Ching Tung Orthokeratology and bi-focal contact lens
JP4855592B2 (ja) * 2001-06-28 2012-01-18 株式会社シード ハードコンタクトレンズ
US20070088415A1 (en) * 2001-11-07 2007-04-19 Minu Llc Method of treating the eye using controlled heat delivery
US20070142828A1 (en) * 2001-11-07 2007-06-21 Minu, Llc Method and system for altering the refractive properties of the eye
US9370446B2 (en) 2001-11-07 2016-06-21 Gholam A. Peyman Method of altering the refractive properties of an eye
US9681984B2 (en) 2001-11-07 2017-06-20 Gholam A. Peyman Method of altering the refractive properties of an eye
US20050149006A1 (en) * 2001-11-07 2005-07-07 Peyman Gholam A. Device and method for reshaping the cornea
US9155652B2 (en) * 2001-11-07 2015-10-13 Gholam A. Peyman Method for laser correction of refractive errors of an eye with a thin cornea
US9814567B2 (en) 2001-11-07 2017-11-14 Gholam A. Peyman Method of altering the refractive properties of an eye
US6997553B2 (en) * 2002-08-07 2006-02-14 Global-Ok Vision, Inc. Contact lens for reshaping the altered corneas of post refractive surgery, previous ortho-K of keratoconus
US6969514B2 (en) * 2003-02-05 2005-11-29 Soll David B Method for treating elevated intraocular pressure, including glaucoma
US7101042B2 (en) * 2003-08-12 2006-09-05 S.I.B. Investments Llc Multifocal contact lens
MXPA03011987A (es) 2003-12-19 2005-06-23 Osio Sancho Alberto Metodo para el tratamiento de la presbicia induciendo cambios en el poder y fisiologia corneal.
ES2322850T3 (es) * 2004-02-03 2009-06-30 Iroc Ag Dispositivo oftalmologico.
PT1729797E (pt) * 2004-03-22 2008-12-17 Solvay Pharm Gmbh Composições farmacêuticas orais de produtos contendo lipase, em particular de pancreatina, contendo tensioactivos
US20060276777A1 (en) * 2005-04-08 2006-12-07 Coroneo Minas T Corneal shaping
JP5140586B2 (ja) 2005-07-29 2013-02-06 アボット プロダクツ ゲゼルシャフト ミット ベシュレンクテル ハフツング 滅菌パンクレアチン粉末の製法
US11266607B2 (en) * 2005-08-15 2022-03-08 AbbVie Pharmaceuticals GmbH Process for the manufacture and use of pancreatin micropellet cores
US9198871B2 (en) * 2005-08-15 2015-12-01 Abbott Products Gmbh Delayed release pancreatin compositions
ES2527284T3 (es) * 2005-08-24 2015-01-22 Hecht Contactlinsen Gmbh Lente de contacto de forma estable
DE102005056958A1 (de) * 2005-11-29 2007-06-06 Rowiak Gmbh Verfahren und Vorrichtung zum Bearbeiten eines Werkstücks
WO2007082127A2 (en) * 2006-01-05 2007-07-19 El Hage Sami G Combination therapy for long-lasting ckrtm
EP2004209B1 (de) * 2006-04-13 2013-07-24 Euclid Systems Corporation Zusammensetzung und verfahren zur stabilisierung des hornhautgewebes nach einem refraktiven chirurgischen eingriff
US10072256B2 (en) * 2006-05-22 2018-09-11 Abbott Products Gmbh Process for separating and determining the viral load in a pancreatin sample
US8202272B2 (en) 2007-07-19 2012-06-19 Avedro, Inc. Eye therapy system
US8992516B2 (en) 2007-07-19 2015-03-31 Avedro, Inc. Eye therapy system
WO2009042159A1 (en) * 2007-09-24 2009-04-02 The Johns Hopkins University Wearable photoactivator for ocular therapeutic applications and use thereof
US8545487B2 (en) * 2007-12-05 2013-10-01 Avedro Inc. Eye therapy system
US8348935B2 (en) 2008-01-23 2013-01-08 Avedro, Inc. System and method for reshaping an eye feature
US8409189B2 (en) * 2008-01-23 2013-04-02 Avedro, Inc. System and method for reshaping an eye feature
US8469952B2 (en) * 2008-01-23 2013-06-25 Avedro, Inc. System and method for positioning an eye therapy device
IT1393402B1 (it) 2008-08-28 2012-04-20 Sooft Italia Spa Uso di enhancer eventualmente con riboflavina, nonche' relative composizioni oftalmiche per cross-linking corneale del cheratocono o di altre patologie ectasiche corneali
US8398628B2 (en) * 2008-09-19 2013-03-19 Avedro, Inc. Eye therapy system
US20100082018A1 (en) * 2008-09-26 2010-04-01 Daryus Panthakey Method and system for reshaping the cornea
US8366689B2 (en) * 2008-09-30 2013-02-05 Avedro, Inc. Method for making structural changes in corneal fibrils
WO2010039979A1 (en) * 2008-10-01 2010-04-08 Avedro, Inc. Eye therapy system
US8882757B2 (en) * 2008-11-11 2014-11-11 Avedro, Inc. Eye therapy system
US8712536B2 (en) 2009-04-02 2014-04-29 Avedro, Inc. Eye therapy system
EP2413832A1 (de) * 2009-04-02 2012-02-08 Avedro, INC. Augentherapiesystem
US8632187B1 (en) * 2009-04-27 2014-01-21 Dakota Sciences, Inc. Progressive multifocal rigid gas permeable contact lens
WO2011050164A1 (en) 2009-10-21 2011-04-28 Avedro, Inc. Eye therapy
US8177778B2 (en) * 2009-10-30 2012-05-15 Avedro, Inc. System and method for stabilizing corneal tissue after treatment
EP4480461A3 (de) 2010-03-19 2025-02-12 Avedro, Inc. Systeme zur anwendung und überwachung einer augentherapie
US20110288466A1 (en) * 2010-04-13 2011-11-24 Avedro, Inc. Systems and methods for activating cross-linking in an eye
US20110280763A1 (en) * 2010-05-17 2011-11-17 Abbott Medical Optics Inc. Light-activated disinfection system
US9622911B2 (en) 2010-09-30 2017-04-18 Cxl Ophthalmics, Llc Ophthalmic treatment device, system, and method of use
US8668333B2 (en) * 2010-12-08 2014-03-11 Valdemar Portney Contra-aspheric toric ophthalmic lens
BR112013017875B1 (pt) * 2011-01-12 2021-06-29 Sooft Italia Spa Composição oftálmica
WO2012162529A1 (en) 2011-05-24 2012-11-29 Avedro, Inc. Systems and methods for reshaping an eye feature
US20140066835A1 (en) * 2011-05-24 2014-03-06 Avedro, Inc. Systems and methods for corneal cross-linking with pulsed light
JP6122845B2 (ja) 2011-06-02 2017-04-26 アヴェドロ・インコーポレーテッドAvedro,Inc. 時間ベースの光活性剤の送達又は光活性マーカの存在をモニターするシステム及び方法
US20120330291A1 (en) * 2011-06-24 2012-12-27 The Regents Of The University Of California Nonlinear optical photodynamic therapy (nlo-pdt) of the cornea
EP2830554A1 (de) 2012-03-29 2015-02-04 CXL Ophthalmics, LLC Okulares vernetzungssystem und verfahren zum verschliessen von wunden in der augenhornhaut
WO2013148896A1 (en) 2012-03-29 2013-10-03 Cxl Ophthalmics, Llc Ocular treatment solutions, delivery devices and delivery augmentation methods
US9566301B2 (en) 2012-03-29 2017-02-14 Cxl Ophthalmics, Llc Compositions and methods for treating or preventing diseases associated with oxidative stress
EP2872081B2 (de) 2012-07-16 2025-07-16 Avedro, Inc. Systeme zur hornhautvernetzung mit gepulstem licht
CN104823100B (zh) * 2012-08-10 2020-04-24 奥西奥公司以约利亚健康公司名义经营 隐形眼镜和为个体的眼睛测定隐形眼镜的适配的方法
US20140113009A1 (en) * 2012-10-24 2014-04-24 Avedro, Inc. Controlled application of cross-linking agent
WO2014117120A2 (en) * 2013-01-28 2014-07-31 The Cleveland Clinic Foundation Corneal stiffening for treating astigmatism
EP2967990A1 (de) 2013-03-15 2016-01-20 Amo Wavefront Sciences, LLC Nichtinvasive refraktive behandlung unter verwendung von nanopartikeln
US9498114B2 (en) 2013-06-18 2016-11-22 Avedro, Inc. Systems and methods for determining biomechanical properties of the eye for applying treatment
US9498122B2 (en) 2013-06-18 2016-11-22 Avedro, Inc. Systems and methods for determining biomechanical properties of the eye for applying treatment
EP3052983B1 (de) 2013-10-04 2024-05-08 Ophtec B.V. Ophthalmische linse zur astigmatismuskorrektur
US20150305933A1 (en) * 2014-04-23 2015-10-29 Carl Zeiss Meditec Ag Integrated device system and method for noninvasive corneal refractive corrections
US11666777B2 (en) 2014-05-12 2023-06-06 Gholam A. Peyman Photodynamic therapy technique for preventing damage to the fovea of the eye or another body portion of a patient
US9937033B1 (en) 2014-05-12 2018-04-10 Gholam A. Peyman Corneal lenslet implantation with a cross-linked cornea
US10195081B1 (en) 2014-05-12 2019-02-05 Gholam A. Peyman Method of prevention of capsular opacification and fibrosis after cataract extraction and/or prevention of fibrosis around a shunt or stent after glaucoma surgery
US10278920B1 (en) * 2014-05-12 2019-05-07 Gholam A. Peyman Drug delivery implant and a method using the same
US11648261B2 (en) 2014-05-12 2023-05-16 Gholam A. Peyman Method of treating, reducing, or alleviating a medical condition in a patient
US10881503B2 (en) 2014-05-12 2021-01-05 Gholam A. Peyman Method of corneal transplantation or corneal inlay implantation with cross-linking
US9427355B1 (en) 2014-05-12 2016-08-30 Gholam A. Peyman Corneal transplantation with a cross-linked cornea
US10206569B1 (en) 2014-05-12 2019-02-19 Gholam A. Peyman Corneal intraocular pressure sensor and a surgical method using the same
US11259914B2 (en) 2014-05-12 2022-03-01 Gholam A. Peyman Molding or 3-D printing of a synthetic refractive corneal lenslet
US12396889B2 (en) 2014-05-12 2025-08-26 Gholam A. Peyman Lamellar corneal autologous or homologous graft in refractive surgery
US10583221B2 (en) 2014-05-12 2020-03-10 Gholam A. Peyman Method of corneal transplantation or corneal inlay implantation with cross-linking
US10709546B2 (en) 2014-05-12 2020-07-14 Gholam A. Peyman Intracorneal lens implantation with a cross-linked cornea
US9744029B1 (en) 2014-05-12 2017-08-29 Gholam A. Peyman Method of preventing capsular opacification and fibrosis utilizing an accommodative intraocular lens implant
US11045352B2 (en) 2014-05-12 2021-06-29 Gholam A. Peyman Methods for treatment of dry eye and other acute or chronic inflammatory processes
US11338059B2 (en) 2014-05-12 2022-05-24 Gholam A. Peyman Method of corneal and scleral inlay crosslinking and preservation
US11565023B2 (en) 2014-05-12 2023-01-31 Gholam A. Peyman Method of corneal transplantation or corneal inlay implantation with cross-linking
US10925889B2 (en) 2014-05-12 2021-02-23 Gholam A. Peyman Method of treating, reducing, or alleviating a medical condition in a patient
US12383393B2 (en) 2014-05-12 2025-08-12 Gholam A. Peyman Ablatable corneal inlay for correction of refractive errors and/or presbyopia
US10314690B1 (en) 2014-05-12 2019-06-11 Gholam A. Peyman Method of corneal transplantation or corneal inlay implantation with cross-linking
JP6644799B2 (ja) 2014-10-27 2020-02-12 アヴェドロ・インコーポレーテッドAvedro,Inc. 眼の架橋処置のためのシステム及び方法
US10114205B2 (en) 2014-11-13 2018-10-30 Avedro, Inc. Multipass virtually imaged phased array etalon
WO2016172695A1 (en) 2015-04-24 2016-10-27 Avedro, Inc. Systems and methods for photoactivating a photosensitizer applied to an eye
EP4483884A3 (de) 2015-05-22 2025-03-05 Avedro Inc. Systeme zur überwachung der vernetzungsaktivität für hornhautbehandlungen
US11207410B2 (en) 2015-07-21 2021-12-28 Avedro, Inc. Systems and methods for treatments of an eye with a photosensitizer
EP3426262B1 (de) * 2016-03-08 2023-08-23 University of Utah Research Foundation Vernetzungsmittel und zugehörige verfahren
WO2017180851A1 (en) 2016-04-13 2017-10-19 Avedro, Inc. Systems and methods for delivering drugs to an eye
EP3559732B1 (de) * 2016-12-23 2025-03-26 Capricornia Contact Lens Pty Ltd Kontaktlinse
WO2019136358A1 (en) * 2018-01-05 2019-07-11 Iveena Delivery Systems, Inc. Treatment of myopic progression
SG10201800855RA (en) * 2018-01-31 2019-08-27 Menicon Co Ltd Apparatus and Methods for Molding Rigid Ocular Lenses
US12042433B2 (en) 2018-03-05 2024-07-23 Avedro, Inc. Systems and methods for eye tracking during eye treatment
WO2019173762A1 (en) 2018-03-08 2019-09-12 Avedro, Inc. Micro-devices for treatment of an eye
US12453652B2 (en) 2018-09-19 2025-10-28 Avedro, Inc. Systems and methods treating for corneal ectatic disorders
EP3852606A4 (de) 2018-09-19 2022-06-22 Avedro Inc. Systeme und verfahren zur augenverfolgung während der augenbehandlung
JP7596262B2 (ja) 2018-10-09 2024-12-09 アヴェドロ・インコーポレーテッド 角膜架橋治療のための光活性化システム及び方法
EP3930648A4 (de) 2019-02-26 2022-11-23 Avedro, Inc. Systeme und verfahren zur vernetzung von behandlungen trockener augen
US11707518B2 (en) 2019-04-28 2023-07-25 Gholam A. Peyman Method of treating, reducing, or alleviating a medical condition in a patient
US12226478B2 (en) 2019-04-28 2025-02-18 Gholam A. Peyman Method of treating, reducing, or alleviating a medical condition in a patient
JP7624433B2 (ja) 2019-08-06 2025-01-30 アヴェドロ・インコーポレーテッド 角膜の架橋治療のための光活性化システム及び方法
KR102077579B1 (ko) * 2019-08-14 2020-02-14 이정훈 각막굴절교정용 렌즈
US12293513B2 (en) 2021-03-08 2025-05-06 Avedro, Inc. Systems and methods for generating patient-specific corneal cross-linking treatment patterns
US20230067787A1 (en) * 2021-08-30 2023-03-02 Miguelangel Salazar Hydro-contact lens
CN114225016B (zh) * 2021-12-02 2024-07-09 北京大学第一医院 一种用于抑制近视及圆锥角膜进展的方法
EP4257080A1 (de) * 2022-04-04 2023-10-11 Consejo Superior de Investigaciones Cientificas Augenbinde

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3728223A (en) 1971-10-08 1973-04-17 Amano Pharma Co Ltd Production of hyaluronidase from a strain of streptomyces
US3760807A (en) 1972-04-07 1973-09-25 C Neefe Method of reshaping the cornea to eliminate refractive errors
GB1382015A (en) * 1973-06-29 1975-01-29 Neefe C W Method of reshaping the cornea to eliminate refractive errors
JPS5413510B2 (de) 1973-08-28 1979-05-31
JPS6033474B2 (ja) 1978-05-11 1985-08-02 藤沢薬品工業株式会社 新規なヒアルロニダ−ゼbmp−8231およびその製造法
US5316926A (en) 1983-11-25 1994-05-31 Miles Inc. Method for the microbiological production of non-antigenic hyaluronic acid
SE456245B (sv) 1986-07-09 1988-09-19 Pharmacia Ab Enzympreparation innehallande krillhyaluronidas
US4881543A (en) 1988-06-28 1989-11-21 Massachusetts Institute Of Technology Combined microwave heating and surface cooling of the cornea
NO164844C (no) 1988-10-24 1990-11-21 Norsk Hydro As Fremgangsmaate ved utvinning av enzymer fra krepsdyr.
WO1990004409A1 (en) * 1988-10-27 1990-05-03 University Of Kentucky Research Foundation Human leukocyte elastase inhibitors and methods of producing and using same
US4897349A (en) 1989-04-28 1990-01-30 Medchem Products, Inc. Biosynthesis of hyaluronic acid
US5015577A (en) 1989-08-29 1991-05-14 Board Of Regents, The University Of Texas System DNA encoding hyaluronate synthase
US5779696A (en) 1990-07-23 1998-07-14 Sunrise Technologies International, Inc. Method and apparatus for performing corneal reshaping to correct ocular refractive errors
US5270051A (en) 1991-10-15 1993-12-14 Harris Donald H Enzyme-orthokeratology
US5788957A (en) 1991-10-15 1998-08-04 Advanced Corneal Systems, Inc. Enzyme-orthokeratology
US5593877A (en) 1993-03-11 1997-01-14 The Rockefeller University Nucleic acid and recombinant production of vespid venom hyaluronidase
US5496726A (en) 1993-04-16 1996-03-05 Lucky Limited Streptococcus zooepidemicus medium and process for preparing hyaluronic acid
US5749871A (en) 1993-08-23 1998-05-12 Refractec Inc. Method and apparatus for modifications of visual acuity by thermal means
US5611805A (en) 1993-11-12 1997-03-18 Hall; Gary W. Method and device for determining placement of keratotomy incisions
EP0782850A4 (de) 1994-10-13 1998-03-04 Wakamoto Pharma Co Ltd Lyophilisierte zubereitung zur herstellung eines reversibel thermogelierenden arzniemittels auf wasserbasis
US5699810A (en) 1994-11-10 1997-12-23 Pallikaris; Ioannis G. Procedure for removal of soft eye tissue
US5695509A (en) * 1995-03-10 1997-12-09 El Hage; Sami G. Aspherical optical molds for continuous reshaping the cornea based on topographical analysis
US5747027A (en) 1995-04-07 1998-05-05 The Regents Of The University Of California BH55 hyaluronidase
US5697945A (en) 1995-07-27 1997-12-16 Black Hills Regional Eye Institute Corneal surface marker and marking method for reducing irregular astigmatism during lamellar (LASIK) corneal surgery
US5866120A (en) 1995-11-22 1999-02-02 Advanced Corneal Systems, Inc. Method for accelerating clearance of hemorrhagic blood from the vitreous humor with hyaluronidase
US6123938A (en) 1996-10-17 2000-09-26 The Regents Of The University Of California Human urinary hyaluronidase
BR9809558A (pt) 1997-05-22 2000-07-04 Advanced Corneal Systems Inc Uso de hialuronidase na fabricação de um preparado oftálmico para liquefazer o humor vìtreo no tratamento de perturbações do olho
US6161544A (en) 1998-01-28 2000-12-19 Keratoform, Inc. Methods for accelerated orthokeratology
BR9908692A (pt) * 1998-03-09 2001-12-04 Ista Pharmaceuticals Inc Uso de agentes de enrijecimento corneal emortocerotologia enzimática
DE69926053T2 (de) 1999-04-27 2006-04-27 Transgene S.A. Verfahren zur Herstellung von Säugetier-Zellinien
AU6149300A (en) 1999-06-12 2001-01-02 Merck Patent Gmbh Hyaluronidase from the hirudinaria manillensis, isolation, purification and recombinant method of production

Also Published As

Publication number Publication date
JP2002506013A (ja) 2002-02-26
BR9908692A (pt) 2001-12-04
WO1999045869A1 (en) 1999-09-16
US20030175259A1 (en) 2003-09-18
EP1061873B1 (de) 2005-11-02
AU758862B2 (en) 2003-04-03
US6537545B1 (en) 2003-03-25
EP1061873A1 (de) 2000-12-27
CN1299257A (zh) 2001-06-13
CA2323199A1 (en) 1999-09-16
DE69928087D1 (de) 2005-12-08
KR20010041806A (ko) 2001-05-25
AU3073999A (en) 1999-09-27
CN1200698C (zh) 2005-05-11

Similar Documents

Publication Publication Date Title
ATE308293T1 (de) Verwendung von glyceraldehyde als hornhaut härtungsmitteln
BR9206629A (pt) Ortoqueratologia enzimática
EP2294475B1 (de) Weiche kontaktlinsen zur behandlung von fehlsichtigkeit
US6543897B1 (en) Orthokeratology contact lens
JP2011514359A (ja) 角膜脆弱性疾患を治療するための紫外線の照射
US3948871A (en) Composition for hard type contact lens with wettable surface
ATE540332T1 (de) Augenoptische linsen
WO2005062818A3 (en) Treatment of ophthalmic conditions
ATE475115T1 (de) Orthokeratologie und bifokal-kontaktlinse
CA2533304A1 (en) Junctionless ophthalmic lenses and methods for making same
AR027493A1 (es) Disposicion y metodo para integrar datos topograficos de la cornea y datos de frente de onda ocular con mediciones de amtropia primaria a fin de crear undiseno de lente de contacto blanda.
RU2008145675A (ru) Имплантат роговицы и методы коррекции аметропии человеческого глаза
ATE300923T1 (de) Implantat zur korrektur der presbyopie im phaken auge
EP1159941A3 (de) Zusammensetzung zur Verwendung in der Enzymkeratologie
US20130053952A1 (en) Cornea reshaping
KR20130004235U (ko) 각막 복원기능을 가지고 있는 콘택트렌즈
JP2015036080A (ja) 矯正角膜クロスリンキング用コンタクトレンズ及び矯正角膜のクロスリンキング方法
CN118126258A (zh) 一种采用水凝胶制作隐形眼镜的方法
TR2023019496A1 (tr) Enjekte Edilebilir Sertleşen Biyomalzeme Uygulaması ile Korneanın Güçlendirilmesi
KR20010016207A (ko) 콘택트 렌즈의 재료 및 구조
RU98117404A (ru) Способ стабилизации острого зрения и устройство для его осуществления
Vinciguerra et al. Photorefractive keratectomy (PRK) with variable optical zone diameters for the correction of compound myopic astigmatism

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties