MX9709698A - Composicion para la liberacion sostenida de hormona de crecimiento humano. - Google Patents
Composicion para la liberacion sostenida de hormona de crecimiento humano.Info
- Publication number
- MX9709698A MX9709698A MX9709698A MX9709698A MX9709698A MX 9709698 A MX9709698 A MX 9709698A MX 9709698 A MX9709698 A MX 9709698A MX 9709698 A MX9709698 A MX 9709698A MX 9709698 A MX9709698 A MX 9709698A
- Authority
- MX
- Mexico
- Prior art keywords
- composition
- sustained release
- hgh
- biologically active
- polymer
- Prior art date
Links
- 102000002265 Human Growth Hormone Human genes 0.000 title abstract 9
- 108010000521 Human Growth Hormone Proteins 0.000 title abstract 9
- 239000000854 Human Growth Hormone Substances 0.000 title abstract 9
- 239000000203 mixture Substances 0.000 title abstract 9
- 238000013268 sustained release Methods 0.000 title abstract 7
- 239000012730 sustained-release form Substances 0.000 title abstract 7
- 238000000034 method Methods 0.000 abstract 6
- 239000002245 particle Substances 0.000 abstract 4
- 229920000642 polymer Polymers 0.000 abstract 4
- 229920000249 biocompatible polymer Polymers 0.000 abstract 3
- 230000036765 blood level Effects 0.000 abstract 2
- 239000011159 matrix material Substances 0.000 abstract 2
- 230000002459 sustained effect Effects 0.000 abstract 2
- 239000006185 dispersion Substances 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/27—Growth hormone [GH], i.e. somatotropin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1611—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Endocrinology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Nanotechnology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Crystallography & Structural Chemistry (AREA)
- Biotechnology (AREA)
- Inorganic Chemistry (AREA)
- Biophysics (AREA)
- Medical Informatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Abstract
Esta invencion se refiere a una composicion, y métodos de formar y usar dicha composicion, para la liberacion sostenida de homona del crecimiento humano estabilizada, biologicamente activa (hGH). La composicion de liberacion sostenida de esta invencion incluye una matriz polimérica de un polímero biocompatible y partículas de hGH estabilizada por cation de metal, biologicamente activa, donde dichas partículas están dispersadas dentro del polímero biocompatible.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/473,544 US5654010A (en) | 1992-12-02 | 1995-06-07 | Composition for sustained release of human growth hormone |
US08/477,725 US5667808A (en) | 1992-12-02 | 1995-06-07 | Composition for sustained release of human growth hormone |
Publications (1)
Publication Number | Publication Date |
---|---|
MX9709698A true MX9709698A (es) | 1998-07-31 |
Family
ID=27044171
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9709698A MX9709698A (es) | 1995-06-07 | 1997-12-05 | Composicion para la liberacion sostenida de hormona de crecimiento humano. |
Country Status (22)
Country | Link |
---|---|
EP (1) | EP0831787B1 (es) |
JP (1) | JPH11506740A (es) |
CN (1) | CN1102854C (es) |
AT (1) | ATE204468T1 (es) |
AU (1) | AU708756B2 (es) |
BR (1) | BR9608542A (es) |
CA (1) | CA2223436A1 (es) |
CZ (1) | CZ288147B6 (es) |
DE (1) | DE69614685T2 (es) |
DK (1) | DK0831787T3 (es) |
ES (1) | ES2161366T3 (es) |
HK (1) | HK1009089A1 (es) |
HU (1) | HUP9900870A3 (es) |
IL (1) | IL122385A (es) |
MX (1) | MX9709698A (es) |
NO (1) | NO316104B1 (es) |
NZ (1) | NZ310644A (es) |
PL (1) | PL184531B1 (es) |
PT (1) | PT831787E (es) |
RU (1) | RU2161502C2 (es) |
SK (1) | SK281571B6 (es) |
WO (1) | WO1996040072A2 (es) |
Families Citing this family (95)
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MY118835A (en) * | 1997-04-18 | 2005-01-31 | Ipsen Pharma Biotech | Sustained release compositions and the process for their preparation |
US6306826B1 (en) | 1997-06-04 | 2001-10-23 | The Regents Of The University Of California | Treatment of heart failure with growth hormone |
US6663899B2 (en) | 1997-06-13 | 2003-12-16 | Genentech, Inc. | Controlled release microencapsulated NGF formulation |
US6113947A (en) * | 1997-06-13 | 2000-09-05 | Genentech, Inc. | Controlled release microencapsulated NGF formulation |
US6191107B1 (en) * | 1997-09-26 | 2001-02-20 | Takeda Chemical Industries, Ltd. | Complex of human growth hormone and zinc |
NZ525914A (en) | 1998-03-10 | 2004-03-26 | Genentech Inc | Novel polypeptides and nucleic acids encoding the same |
EP3112468A1 (en) | 1998-05-15 | 2017-01-04 | Genentech, Inc. | Il-17 homologous polypeptides and therapeutic uses thereof |
DK1076703T4 (da) | 1998-05-15 | 2011-03-28 | Genentech Inc | Terapeutiske anvendelser af IL-17-homologe polypeptider |
US20020172678A1 (en) | 2000-06-23 | 2002-11-21 | Napoleone Ferrara | EG-VEGF nucleic acids and polypeptides and methods of use |
US7173115B2 (en) | 2000-01-13 | 2007-02-06 | Genentech, Inc. | Stra6 polypeptides |
AU5152700A (en) | 1999-06-15 | 2001-01-02 | Genentech Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
EP1690872A3 (en) | 1999-12-01 | 2006-08-23 | Genentech, Inc. | Composition and methods for the diagnosis of tumours |
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ES2266187T3 (es) | 2000-03-24 | 2007-03-01 | Genentech, Inc. | Uso de la insulina para el tratamiento de trastornos del cartilago. |
US6998137B2 (en) * | 2000-04-07 | 2006-02-14 | Macromed, Inc. | Proteins deposited onto sparingly soluble biocompatible particles for controlled protein release into a biological environment from a polymer matrix |
AU6531101A (en) | 2000-06-02 | 2001-12-17 | Genentech Inc | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
EP2014298A3 (en) | 2000-08-24 | 2009-10-07 | Genentech, Inc. | Interleukin-22 polypeptides, nucleic acids encoding the same and methods for the treatment of pancreatic disorders |
EP1944317A3 (en) | 2000-09-01 | 2008-09-17 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US6673580B2 (en) | 2000-10-27 | 2004-01-06 | Genentech, Inc. | Identification and modification of immunodominant epitopes in polypeptides |
EP1356809A4 (en) | 2000-12-28 | 2008-05-14 | Takeda Pharmaceutical | SUSTAINED RELEASE PREPARATIONS |
AU2002342653A1 (en) | 2001-05-14 | 2002-11-25 | The Gouvernment Of The United States Of America, Represented By The Secretary, Department Of Health | Modified growth hormone |
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US7481997B1 (en) | 2004-02-12 | 2009-01-27 | Montana State University | Snow mountain virus genome sequence, virus-like particles and methods of use |
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Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5656297A (en) * | 1992-03-12 | 1997-08-12 | Alkermes Controlled Therapeutics, Incorporated | Modulated release from biocompatible polymers |
DK0674506T3 (da) * | 1992-12-02 | 2001-01-08 | Alkermes Inc | Væksthormonholdige mikrosfærer med styret frigivelse |
ES2151079T3 (es) * | 1994-09-09 | 2000-12-16 | Takeda Chemical Industries Ltd | Preparacion de liberacion sostenida que contiene una sal metalica de un peptido. |
-
1996
- 1996-06-03 AU AU61469/96A patent/AU708756B2/en not_active Ceased
- 1996-06-03 RU RU97119935/14A patent/RU2161502C2/ru not_active IP Right Cessation
- 1996-06-03 NZ NZ310644A patent/NZ310644A/xx unknown
- 1996-06-03 WO PCT/US1996/008086 patent/WO1996040072A2/en not_active Application Discontinuation
- 1996-06-03 JP JP9500870A patent/JPH11506740A/ja active Pending
- 1996-06-03 CN CN96194614A patent/CN1102854C/zh not_active Expired - Fee Related
- 1996-06-03 IL IL12238596A patent/IL122385A/xx not_active IP Right Cessation
- 1996-06-03 BR BR9608542-8A patent/BR9608542A/pt not_active Application Discontinuation
- 1996-06-03 DK DK96919016T patent/DK0831787T3/da active
- 1996-06-03 PT PT96919016T patent/PT831787E/pt unknown
- 1996-06-03 CZ CZ19973907A patent/CZ288147B6/cs not_active IP Right Cessation
- 1996-06-03 HU HU9900870A patent/HUP9900870A3/hu unknown
- 1996-06-03 DE DE69614685T patent/DE69614685T2/de not_active Expired - Fee Related
- 1996-06-03 SK SK1671-97A patent/SK281571B6/sk unknown
- 1996-06-03 ES ES96919016T patent/ES2161366T3/es not_active Expired - Lifetime
- 1996-06-03 PL PL96323832A patent/PL184531B1/pl not_active IP Right Cessation
- 1996-06-03 AT AT96919016T patent/ATE204468T1/de not_active IP Right Cessation
- 1996-06-03 EP EP96919016A patent/EP0831787B1/en not_active Expired - Lifetime
- 1996-06-03 CA CA002223436A patent/CA2223436A1/en not_active Abandoned
-
1997
- 1997-12-05 NO NO19975708A patent/NO316104B1/no unknown
- 1997-12-05 MX MX9709698A patent/MX9709698A/es not_active IP Right Cessation
-
1998
- 1998-08-19 HK HK98110029A patent/HK1009089A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
RU2161502C2 (ru) | 2001-01-10 |
WO1996040072A3 (en) | 1997-01-23 |
CA2223436A1 (en) | 1996-12-19 |
SK281571B6 (sk) | 2001-05-10 |
CN1187120A (zh) | 1998-07-08 |
NO975708D0 (no) | 1997-12-05 |
IL122385A0 (en) | 1998-06-15 |
HUP9900870A3 (en) | 2001-04-28 |
ES2161366T3 (es) | 2001-12-01 |
DK0831787T3 (da) | 2001-12-17 |
NO316104B1 (no) | 2003-12-15 |
DE69614685D1 (de) | 2001-09-27 |
PL323832A1 (en) | 1998-04-27 |
EP0831787A2 (en) | 1998-04-01 |
PT831787E (pt) | 2002-02-28 |
CZ390797A3 (cs) | 1998-07-15 |
IL122385A (en) | 2001-01-11 |
AU6146996A (en) | 1996-12-30 |
CZ288147B6 (en) | 2001-05-16 |
HK1009089A1 (en) | 1999-09-10 |
JPH11506740A (ja) | 1999-06-15 |
WO1996040072A2 (en) | 1996-12-19 |
NO975708L (no) | 1998-02-05 |
ATE204468T1 (de) | 2001-09-15 |
PL184531B1 (pl) | 2002-11-29 |
EP0831787B1 (en) | 2001-08-22 |
DE69614685T2 (de) | 2002-06-27 |
SK167197A3 (en) | 1998-06-03 |
BR9608542A (pt) | 1999-11-30 |
HUP9900870A2 (hu) | 1999-09-28 |
AU708756B2 (en) | 1999-08-12 |
CN1102854C (zh) | 2003-03-12 |
NZ310644A (en) | 1999-08-30 |
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