MX360599B - Piridinonas bicíclicas novedosas. - Google Patents

Piridinonas bicíclicas novedosas.

Info

Publication number
MX360599B
MX360599B MX2015003637A MX2015003637A MX360599B MX 360599 B MX360599 B MX 360599B MX 2015003637 A MX2015003637 A MX 2015003637A MX 2015003637 A MX2015003637 A MX 2015003637A MX 360599 B MX360599 B MX 360599B
Authority
MX
Mexico
Prior art keywords
novel bicyclic
compounds
pyridinones
bicyclic pyridinones
disclosed
Prior art date
Application number
MX2015003637A
Other languages
English (en)
Spanish (es)
Other versions
MX2015003637A (es
Inventor
Cory Michael Stiff
Douglas Scott Johnson
Chakrapani Subramanyam
Patrick Robert Verhoest
Christopher John O'donnell
Antonia Friederike Stepan
Michael Eric Green
Gregory Wayne Kauffman
Nandini Chaturbhai Patel
Martin Youngjin Pettersson
Tuan Phong Tran
William Am Ende Christopher
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of MX2015003637A publication Critical patent/MX2015003637A/es
Publication of MX360599B publication Critical patent/MX360599B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Epidemiology (AREA)
  • Pyridine Compounds (AREA)
MX2015003637A 2012-09-21 2013-09-06 Piridinonas bicíclicas novedosas. MX360599B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261703969P 2012-09-21 2012-09-21
PCT/IB2013/058347 WO2014045156A1 (en) 2012-09-21 2013-09-06 Novel bicyclic pyridinones

Publications (2)

Publication Number Publication Date
MX2015003637A MX2015003637A (es) 2015-06-05
MX360599B true MX360599B (es) 2018-11-08

Family

ID=49585452

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015003637A MX360599B (es) 2012-09-21 2013-09-06 Piridinonas bicíclicas novedosas.

Country Status (46)

Country Link
US (3) US8916564B2 (index.php)
EP (1) EP2897956B1 (index.php)
JP (1) JP5844018B2 (index.php)
KR (1) KR101725696B1 (index.php)
CN (1) CN104662021B (index.php)
AP (1) AP2015008277A0 (index.php)
AR (1) AR092628A1 (index.php)
AU (1) AU2013319845B2 (index.php)
BR (1) BR112015006436A2 (index.php)
CA (1) CA2882386C (index.php)
CL (1) CL2015000717A1 (index.php)
CR (1) CR20150053A (index.php)
CU (1) CU20150021A7 (index.php)
CY (1) CY1118662T1 (index.php)
DK (1) DK2897956T3 (index.php)
DO (1) DOP2015000069A (index.php)
EA (1) EA026668B1 (index.php)
EC (1) ECSP15015594A (index.php)
ES (1) ES2609987T3 (index.php)
GE (1) GEP201706659B (index.php)
GT (1) GT201500069A (index.php)
HR (1) HRP20161558T1 (index.php)
HU (1) HUE031248T2 (index.php)
IL (1) IL237163A (index.php)
IN (1) IN2015DN01119A (index.php)
LT (1) LT2897956T (index.php)
MA (1) MA37886B1 (index.php)
MD (1) MD4583B1 (index.php)
ME (1) ME02571B (index.php)
MX (1) MX360599B (index.php)
MY (1) MY181891A (index.php)
NI (1) NI201500038A (index.php)
NZ (1) NZ704863A (index.php)
PE (1) PE20150686A1 (index.php)
PH (1) PH12015500376B1 (index.php)
PL (1) PL2897956T3 (index.php)
PT (1) PT2897956T (index.php)
RS (1) RS55426B1 (index.php)
SG (1) SG11201501074WA (index.php)
SI (1) SI2897956T1 (index.php)
TN (1) TN2015000084A1 (index.php)
TW (1) TWI500616B (index.php)
UA (1) UA110688C2 (index.php)
UY (1) UY35039A (index.php)
WO (1) WO2014045156A1 (index.php)
ZA (1) ZA201501195B (index.php)

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ES2742078T3 (es) * 2013-10-04 2020-02-13 Pfizer Piridonas bicíclicas novedosas como moduladores de gamma-secretasa
US10562897B2 (en) 2014-01-16 2020-02-18 Janssen Pharmaceutica Nv Substituted 3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-diones as gamma secretase modulators
SG11201607465UA (en) * 2014-04-01 2016-10-28 Pfizer Chromene and 1,1 a,2,7b-tetrahydrocyclopropa[c]chromene pyridopyrazinediones as gamma-secretase modulators
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CN110337291A (zh) * 2016-12-16 2019-10-15 帕珀莱恩医疗公司 治疗耳蜗突触病变的方法
KR20210084484A (ko) 2018-10-02 2021-07-07 프리퀀시 테라퓨틱스, 인크. 귀 치료제를 포함하는 약제학적 조성물 및 관련 방법
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WO2020210388A1 (en) 2019-04-08 2020-10-15 Frequency Therapeutics, Inc. Combination of chir99021 and valproic acid for treating hearing loss
CR20220316A (es) 2019-12-06 2022-10-07 Vertex Pharma Tetrahidrofuranos sustituidos como moduladores de canales de sodio
CN113402490B (zh) * 2021-03-29 2023-01-03 白银京宇新药业有限公司 一种1，2，6，7-四氢-8H-茚并[5，4-b]呋喃-8-酮的制备方法
SMT202500481T1 (it) 2021-06-04 2026-01-12 Vertex Pharma N-(idrossialchil(etero)aril)tetraidrofuran carbossammidi come modulatori di canali del sodio
CN114034792B (zh) * 2021-11-09 2024-06-25 山东新华制药股份有限公司 检测氯酮含量的液相色谱分析方法

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