MA37886B1 - Nouvelles pyridinones bicycliques - Google Patents

Nouvelles pyridinones bicycliques

Info

Publication number
MA37886B1
MA37886B1 MA37886A MA37886A MA37886B1 MA 37886 B1 MA37886 B1 MA 37886B1 MA 37886 A MA37886 A MA 37886A MA 37886 A MA37886 A MA 37886A MA 37886 B1 MA37886 B1 MA 37886B1
Authority
MA
Morocco
Prior art keywords
new bicyclic
compounds
pyridinones
bicyclic pyridinones
methods
Prior art date
Application number
MA37886A
Other languages
English (en)
Other versions
MA37886A1 (fr
Inventor
Antonia Friederike Stepan
Patrick Robert Verhoest
Ende Christopher William Am
Michael Eric Green
Douglas Scott Johnson
Gregory Wayne Kauffman
Christopher John O'donnell
Nandini Chaturbhai Patel
Martin Youngjin Pettersson
Cory Michael Stiff
Chakrapani Subramanyam
Tuan Phong Tran
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of MA37886A1 publication Critical patent/MA37886A1/fr
Publication of MA37886B1 publication Critical patent/MA37886B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Epidemiology (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

La présente invention concerne des composés et des sels pharmaceutiquement acceptables desdits composés, lesdits composés présentant une structure répondant à la formule (i) telle que définie dans la description. L'invention concerne également des compositions pharmaceutiques correspondantes, des méthodes de traitement, des procédés de synthèse et des intermédiaires.
MA37886A 2012-09-21 2013-09-05 Nouvelles pyridinones bicycliques MA37886B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261703969P 2012-09-21 2012-09-21
PCT/IB2013/058347 WO2014045156A1 (fr) 2012-09-21 2013-09-06 Nouvelles pyridinones bicycliques

Publications (2)

Publication Number Publication Date
MA37886A1 MA37886A1 (fr) 2016-02-29
MA37886B1 true MA37886B1 (fr) 2016-09-30

Family

ID=49585452

Family Applications (1)

Application Number Title Priority Date Filing Date
MA37886A MA37886B1 (fr) 2012-09-21 2013-09-05 Nouvelles pyridinones bicycliques

Country Status (47)

Country Link
US (3) US8916564B2 (fr)
EP (1) EP2897956B1 (fr)
JP (1) JP5844018B2 (fr)
KR (1) KR101725696B1 (fr)
CN (1) CN104662021B (fr)
AP (1) AP2015008277A0 (fr)
AR (1) AR092628A1 (fr)
AU (1) AU2013319845B2 (fr)
BR (1) BR112015006436A2 (fr)
CA (1) CA2882386C (fr)
CL (1) CL2015000717A1 (fr)
CR (1) CR20150053A (fr)
CU (1) CU20150021A7 (fr)
CY (1) CY1118662T1 (fr)
DK (1) DK2897956T3 (fr)
DO (1) DOP2015000069A (fr)
EA (1) EA026668B1 (fr)
EC (1) ECSP15015594A (fr)
ES (1) ES2609987T3 (fr)
GE (1) GEP201706659B (fr)
GT (1) GT201500069A (fr)
HK (1) HK1206013A1 (fr)
HR (1) HRP20161558T1 (fr)
HU (1) HUE031248T2 (fr)
IL (1) IL237163A (fr)
IN (1) IN2015DN01119A (fr)
LT (1) LT2897956T (fr)
MA (1) MA37886B1 (fr)
MD (1) MD4583B1 (fr)
ME (1) ME02571B (fr)
MX (1) MX360599B (fr)
MY (1) MY181891A (fr)
NI (1) NI201500038A (fr)
NZ (1) NZ704863A (fr)
PE (1) PE20150686A1 (fr)
PH (1) PH12015500376B1 (fr)
PL (1) PL2897956T3 (fr)
PT (1) PT2897956T (fr)
RS (1) RS55426B1 (fr)
SG (1) SG11201501074WA (fr)
SI (1) SI2897956T1 (fr)
TN (1) TN2015000084A1 (fr)
TW (1) TWI500616B (fr)
UA (1) UA110688C2 (fr)
UY (1) UY35039A (fr)
WO (1) WO2014045156A1 (fr)
ZA (1) ZA201501195B (fr)

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UA110688C2 (uk) 2012-09-21 2016-01-25 Пфайзер Інк. Біциклічні піридинони
CN104918938B (zh) 2012-12-20 2017-08-15 詹森药业有限公司 新颖的作为γ分泌酶调节剂的三环3，4‑二氢‑2H‑吡啶并[1，2‑a]吡嗪‑1，6‑二酮衍生物
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ES2759277T3 (es) * 2014-04-01 2020-05-08 Pfizer Cromeno y 1,1a,2,7b-tetrahidrociclopropa[c]cromeno piridopiracinadionionas como moduladores de gamma-secretasa
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MA55611A (fr) 2019-04-08 2022-02-16 Frequency Therapeutics Inc Association de chir99021 et d'acide valproïque pour traiter une perte auditive
TW202128675A (zh) 2019-12-06 2021-08-01 美商維泰克斯製藥公司 作為鈉通道調節劑之經取代四氫呋喃
CN113402490B (zh) * 2021-03-29 2023-01-03 白银京宇新药业有限公司 一种1，2，6，7-四氢-8H-茚并[5，4-b]呋喃-8-酮的制备方法
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