MX360599B - Piridinonas bicíclicas novedosas. - Google Patents

Piridinonas bicíclicas novedosas.

Info

Publication number
MX360599B
MX360599B MX2015003637A MX2015003637A MX360599B MX 360599 B MX360599 B MX 360599B MX 2015003637 A MX2015003637 A MX 2015003637A MX 2015003637 A MX2015003637 A MX 2015003637A MX 360599 B MX360599 B MX 360599B
Authority
MX
Mexico
Prior art keywords
novel bicyclic
compounds
pyridinones
bicyclic pyridinones
disclosed
Prior art date
Application number
MX2015003637A
Other languages
English (en)
Other versions
MX2015003637A (es
Inventor
Cory Michael Stiff
Douglas Scott Johnson
Chakrapani Subramanyam
Patrick Robert Verhoest
Christopher John O'donnell
Antonia Friederike Stepan
Michael Eric Green
Gregory Wayne Kauffman
Nandini Chaturbhai Patel
Martin Youngjin Pettersson
Tuan Phong Tran
William Am Ende Christopher
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of MX2015003637A publication Critical patent/MX2015003637A/es
Publication of MX360599B publication Critical patent/MX360599B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Epidemiology (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Se describen compuestos y sales farmacéuticamente aceptables de los compuestos, en donde los compuestos tienen la estructura de la Fórmula I (ver Fórmula) como se define en la especificación; se describen también las composiciones farmacéuticas, métodos de tratamiento, métodos de síntesis e intermediarios correspondientes.
MX2015003637A 2012-09-21 2013-09-06 Piridinonas bicíclicas novedosas. MX360599B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261703969P 2012-09-21 2012-09-21
PCT/IB2013/058347 WO2014045156A1 (en) 2012-09-21 2013-09-06 Novel bicyclic pyridinones

Publications (2)

Publication Number Publication Date
MX2015003637A MX2015003637A (es) 2015-06-05
MX360599B true MX360599B (es) 2018-11-08

Family

ID=49585452

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015003637A MX360599B (es) 2012-09-21 2013-09-06 Piridinonas bicíclicas novedosas.

Country Status (47)

Country Link
US (3) US8916564B2 (es)
EP (1) EP2897956B1 (es)
JP (1) JP5844018B2 (es)
KR (1) KR101725696B1 (es)
CN (1) CN104662021B (es)
AP (1) AP2015008277A0 (es)
AR (1) AR092628A1 (es)
AU (1) AU2013319845B2 (es)
BR (1) BR112015006436A2 (es)
CA (1) CA2882386C (es)
CL (1) CL2015000717A1 (es)
CR (1) CR20150053A (es)
CU (1) CU20150021A7 (es)
CY (1) CY1118662T1 (es)
DK (1) DK2897956T3 (es)
DO (1) DOP2015000069A (es)
EA (1) EA026668B1 (es)
EC (1) ECSP15015594A (es)
ES (1) ES2609987T3 (es)
GE (1) GEP201706659B (es)
GT (1) GT201500069A (es)
HK (1) HK1206013A1 (es)
HR (1) HRP20161558T1 (es)
HU (1) HUE031248T2 (es)
IL (1) IL237163A (es)
IN (1) IN2015DN01119A (es)
LT (1) LT2897956T (es)
MA (1) MA37886B1 (es)
MD (1) MD4583B1 (es)
ME (1) ME02571B (es)
MX (1) MX360599B (es)
MY (1) MY181891A (es)
NI (1) NI201500038A (es)
NZ (1) NZ704863A (es)
PE (1) PE20150686A1 (es)
PH (1) PH12015500376A1 (es)
PL (1) PL2897956T3 (es)
PT (1) PT2897956T (es)
RS (1) RS55426B1 (es)
SG (1) SG11201501074WA (es)
SI (1) SI2897956T1 (es)
TN (1) TN2015000084A1 (es)
TW (1) TWI500616B (es)
UA (1) UA110688C2 (es)
UY (1) UY35039A (es)
WO (1) WO2014045156A1 (es)
ZA (1) ZA201501195B (es)

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CN104936958B (zh) 2013-01-17 2019-07-26 詹森药业有限公司 作为γ分泌酶调节剂的新颖的经取代的吡啶并-哌嗪酮衍生物
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SG11202111191YA (en) 2019-04-08 2021-11-29 Frequency Therapeutics Inc Combination of chir99021 and valproic acid for treating hearing loss
IL293592A (en) 2019-12-06 2022-08-01 Vertex Pharma Transduced tetrahydrofurans as sodium channel modulators
CN113402490B (zh) * 2021-03-29 2023-01-03 白银京宇新药业有限公司 一种1，2，6，7-四氢-8H-茚并[5，4-b]呋喃-8-酮的制备方法
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CN114034792B (zh) * 2021-11-09 2024-06-25 山东新华制药股份有限公司 检测氯酮含量的液相色谱分析方法

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