CU20150021A7 - Piridinonas bicíclicas novedosas - Google Patents

Piridinonas bicíclicas novedosas

Info

Publication number
CU20150021A7
CU20150021A7 CUP2015000021A CU20150021A CU20150021A7 CU 20150021 A7 CU20150021 A7 CU 20150021A7 CU P2015000021 A CUP2015000021 A CU P2015000021A CU 20150021 A CU20150021 A CU 20150021A CU 20150021 A7 CU20150021 A7 CU 20150021A7
Authority
CU
Cuba
Prior art keywords
new bicyclic
compounds
pyridinones
bicyclic pyridinones
formula
Prior art date
Application number
CUP2015000021A
Other languages
English (en)
Inventor
Ende Christopher William Am
Michael Eric Green
Douglas Scott Johnson
Gregory Wayne Kauffman
Christopher John O'donnell
Nandini Chaturbhai Patel
Martín Youngjin Pettersson
Antonia Friederike Stepan
Cory Michael Stiff
Chakrapani Subramanyam
Tuan Phong Tran
Patrick Robert Verhoest
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of CU20150021A7 publication Critical patent/CU20150021A7/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Epidemiology (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Se describen compuestos y sales farmacéuticamente aceptables de los compuestos, en donde los compuestos tienen la estructura de la Fórmula I Espacio para Fórmula como se define en la especificación. Se describen también las composiciones farmacéuticas, métodos de tratamiento, métodos de síntesis e intermediarios correspondientes.
CUP2015000021A 2012-09-21 2015-03-06 Piridinonas bicíclicas novedosas CU20150021A7 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261703969P 2012-09-21 2012-09-21
PCT/IB2013/058347 WO2014045156A1 (en) 2012-09-21 2013-09-06 Novel bicyclic pyridinones

Publications (1)

Publication Number Publication Date
CU20150021A7 true CU20150021A7 (es) 2015-08-27

Family

ID=49585452

Family Applications (1)

Application Number Title Priority Date Filing Date
CUP2015000021A CU20150021A7 (es) 2012-09-21 2015-03-06 Piridinonas bicíclicas novedosas

Country Status (47)

Country Link
US (3) US8916564B2 (es)
EP (1) EP2897956B1 (es)
JP (1) JP5844018B2 (es)
KR (1) KR101725696B1 (es)
CN (1) CN104662021B (es)
AP (1) AP2015008277A0 (es)
AR (1) AR092628A1 (es)
AU (1) AU2013319845B2 (es)
BR (1) BR112015006436A2 (es)
CA (1) CA2882386C (es)
CL (1) CL2015000717A1 (es)
CR (1) CR20150053A (es)
CU (1) CU20150021A7 (es)
CY (1) CY1118662T1 (es)
DK (1) DK2897956T3 (es)
DO (1) DOP2015000069A (es)
EA (1) EA026668B1 (es)
EC (1) ECSP15015594A (es)
ES (1) ES2609987T3 (es)
GE (1) GEP201706659B (es)
GT (1) GT201500069A (es)
HK (1) HK1206013A1 (es)
HR (1) HRP20161558T1 (es)
HU (1) HUE031248T2 (es)
IL (1) IL237163A (es)
IN (1) IN2015DN01119A (es)
LT (1) LT2897956T (es)
MA (1) MA37886B1 (es)
MD (1) MD4583B1 (es)
ME (1) ME02571B (es)
MX (1) MX360599B (es)
MY (1) MY181891A (es)
NI (1) NI201500038A (es)
NZ (1) NZ704863A (es)
PE (1) PE20150686A1 (es)
PH (1) PH12015500376A1 (es)
PL (1) PL2897956T3 (es)
PT (1) PT2897956T (es)
RS (1) RS55426B1 (es)
SG (1) SG11201501074WA (es)
SI (1) SI2897956T1 (es)
TN (1) TN2015000084A1 (es)
TW (1) TWI500616B (es)
UA (1) UA110688C2 (es)
UY (1) UY35039A (es)
WO (1) WO2014045156A1 (es)
ZA (1) ZA201501195B (es)

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AU2020397059A1 (en) 2019-12-06 2022-07-21 Vertex Pharmaceuticals Incorporated Substituted tetrahydrofurans as modulators of sodium channels
CN113402490B (zh) * 2021-03-29 2023-01-03 白银京宇新药业有限公司 一种1，2，6，7-四氢-8H-茚并[5，4-b]呋喃-8-酮的制备方法
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