MD4583B1 - Piridinone biciclice noi - Google Patents

Piridinone biciclice noi

Info

Publication number
MD4583B1
MD4583B1 MDA20150023A MD20150023A MD4583B1 MD 4583 B1 MD4583 B1 MD 4583B1 MD A20150023 A MDA20150023 A MD A20150023A MD 20150023 A MD20150023 A MD 20150023A MD 4583 B1 MD4583 B1 MD 4583B1
Authority
MD
Moldova
Prior art keywords
novel bicyclic
pyridinones
compounds
methods
relates
Prior art date
Application number
MDA20150023A
Other languages
English (en)
Russian (ru)
Other versions
MD20150023A2 (ro
Inventor
ЭНДЕ Кристофер Уильям ЭМ
Майкл Эрик Грин
Дуглас Скотт Джонсон
Грегори Уэйн Кауффман
Кристофер Джон О'Доннелл
Нандини Чатурбхай ПАТЕЛ
Мартин Янгчжин Петтерссон
Антония Фредерике СТИПЭН
Кори Майкл Стифф
Чакрапани Субраманиам
Туан Пхон Трэн
Патрик Роберт Верхоуэст
Original Assignee
Pfizer Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc. filed Critical Pfizer Inc.
Publication of MD20150023A2 publication Critical patent/MD20150023A2/ro
Publication of MD4583B1 publication Critical patent/MD4583B1/ro

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Epidemiology (AREA)

Abstract

Invenţia se referă la compuşi şi săruri farmaceutic acceptabile ale acestora, compuşii având structura cu formula IIunde substituenţii au semnificaţiile definite în descrierea invenţiei.Invenţia se referă, de asemenea, la compoziţii farmaceutice care le conţin, procedee de sinteză şi compuşi intermediari, metode de tratament al tulburărilor neurodegenerative şi psihice.
MDA20150023A 2012-09-21 2013-09-06 Piridinone biciclice noi MD4583B1 (ro)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261703969P 2012-09-21 2012-09-21
PCT/IB2013/058347 WO2014045156A1 (en) 2012-09-21 2013-09-06 Novel bicyclic pyridinones

Publications (2)

Publication Number Publication Date
MD20150023A2 MD20150023A2 (ro) 2015-07-31
MD4583B1 true MD4583B1 (ro) 2018-07-31

Family

ID=49585452

Family Applications (1)

Application Number Title Priority Date Filing Date
MDA20150023A MD4583B1 (ro) 2012-09-21 2013-09-06 Piridinone biciclice noi

Country Status (47)

Country Link
US (3) US8916564B2 (ro)
EP (1) EP2897956B1 (ro)
JP (1) JP5844018B2 (ro)
KR (1) KR101725696B1 (ro)
CN (1) CN104662021B (ro)
AP (1) AP2015008277A0 (ro)
AR (1) AR092628A1 (ro)
AU (1) AU2013319845B2 (ro)
BR (1) BR112015006436A2 (ro)
CA (1) CA2882386C (ro)
CL (1) CL2015000717A1 (ro)
CR (1) CR20150053A (ro)
CU (1) CU20150021A7 (ro)
CY (1) CY1118662T1 (ro)
DK (1) DK2897956T3 (ro)
DO (1) DOP2015000069A (ro)
EA (1) EA026668B1 (ro)
EC (1) ECSP15015594A (ro)
ES (1) ES2609987T3 (ro)
GE (1) GEP201706659B (ro)
GT (1) GT201500069A (ro)
HK (1) HK1206013A1 (ro)
HR (1) HRP20161558T1 (ro)
HU (1) HUE031248T2 (ro)
IL (1) IL237163A (ro)
IN (1) IN2015DN01119A (ro)
LT (1) LT2897956T (ro)
MA (1) MA37886B1 (ro)
MD (1) MD4583B1 (ro)
ME (1) ME02571B (ro)
MX (1) MX360599B (ro)
MY (1) MY181891A (ro)
NI (1) NI201500038A (ro)
NZ (1) NZ704863A (ro)
PE (1) PE20150686A1 (ro)
PH (1) PH12015500376A1 (ro)
PL (1) PL2897956T3 (ro)
PT (1) PT2897956T (ro)
RS (1) RS55426B1 (ro)
SG (1) SG11201501074WA (ro)
SI (1) SI2897956T1 (ro)
TN (1) TN2015000084A1 (ro)
TW (1) TWI500616B (ro)
UA (1) UA110688C2 (ro)
UY (1) UY35039A (ro)
WO (1) WO2014045156A1 (ro)
ZA (1) ZA201501195B (ro)

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