MX2014000963A - Derivados de carboxamida y urea aromaticos biciclicos sustituidos como ligandos del receptor de vanilloide. - Google Patents

Derivados de carboxamida y urea aromaticos biciclicos sustituidos como ligandos del receptor de vanilloide.

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Publication number
MX2014000963A
MX2014000963A MX2014000963A MX2014000963A MX2014000963A MX 2014000963 A MX2014000963 A MX 2014000963A MX 2014000963 A MX2014000963 A MX 2014000963A MX 2014000963 A MX2014000963 A MX 2014000963A MX 2014000963 A MX2014000963 A MX 2014000963A
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MX
Mexico
Prior art keywords
receptor ligands
bicyclic aromatic
urea derivatives
substituted bicyclic
vanilloid receptor
Prior art date
Application number
MX2014000963A
Other languages
English (en)
Inventor
Thomas Christoph
Jeewoo Lee
Bernhard Lesch
Robert Frank-Foltyn
Original Assignee
Gruenenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruenenthal Gmbh filed Critical Gruenenthal Gmbh
Publication of MX2014000963A publication Critical patent/MX2014000963A/es

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    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Abstract

La presente invención se refiere a carboxamida aromática bicíclica sustituida y derivados de urea como ligandos del receptor vanilloide, a composiciones farmacéuticas que contienen estos compuestos y también a estos compuestos para uso en el tratamiento y/o profilaxis de dolor y enfermedades y/o trastornos adicionales.
MX2014000963A 2011-07-26 2012-07-25 Derivados de carboxamida y urea aromaticos biciclicos sustituidos como ligandos del receptor de vanilloide. MX2014000963A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11006113 2011-07-26
PCT/EP2012/003136 WO2013013816A1 (en) 2011-07-26 2012-07-25 Substituted bicyclic aromatic carboxamide and urea derivatives as vanilloid receptor ligands

Publications (1)

Publication Number Publication Date
MX2014000963A true MX2014000963A (es) 2014-03-27

Family

ID=46639966

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014000963A MX2014000963A (es) 2011-07-26 2012-07-25 Derivados de carboxamida y urea aromaticos biciclicos sustituidos como ligandos del receptor de vanilloide.

Country Status (9)

Country Link
US (1) US9029378B2 (es)
EP (1) EP2736899A1 (es)
JP (1) JP2014521617A (es)
KR (1) KR20140049028A (es)
AU (1) AU2012289254A1 (es)
BR (1) BR112014001714A2 (es)
CA (1) CA2842976A1 (es)
MX (1) MX2014000963A (es)
WO (1) WO2013013816A1 (es)

Families Citing this family (5)

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Publication number Priority date Publication date Assignee Title
US10270003B2 (en) * 2012-12-04 2019-04-23 Taiwan Semiconductor Manufacturing Company, Ltd. Method and apparatus for CMOS sensor packaging
EP3130590A1 (en) * 2015-08-13 2017-02-15 Grünenthal GmbH Aromatic aza compounds as vr1/trpv1 ligands
US20190275012A9 (en) * 2016-07-29 2019-09-12 Lupin Limited Substituted thiazolo-pyridine compounds as malt1 inhibitors
CN108383782A (zh) * 2018-03-20 2018-08-10 北京凯恩梅格医药科技有限公司 4-氨基喹哪啶的合成方法
WO2022030589A1 (ja) * 2020-08-05 2022-02-10 国立大学法人北海道大学 単座配位尿素化合物を含む配位子とそれを含むホウ素化触媒

Family Cites Families (17)

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Publication number Priority date Publication date Assignee Title
US7202257B2 (en) 2003-12-24 2007-04-10 Deciphera Pharmaceuticals, Llc Anti-inflammatory medicaments
US20050113576A1 (en) * 2003-08-05 2005-05-26 Chih-Hung Lee Fused azabicyclic compounds that inhibit vanilloid receptor subtype 1 (VR1) receptor
EP1747206A1 (en) * 2004-04-29 2007-01-31 Abbott Laboratories Amino-tetrazoles analogues and methods of use
JP2008525502A (ja) 2004-12-23 2008-07-17 デシファラ ファーマスーティカルズ， エルエルシー 抗炎症薬
NZ593684A (en) 2005-10-19 2012-11-30 Gruenenthal Chemie Novel vanilloid receptor ligands and their use for producing medicaments
TWI325423B (en) 2005-10-28 2010-06-01 Lilly Co Eli Kinase inhibitors
WO2007113548A1 (en) 2006-04-06 2007-10-11 Astrazeneca Ab Naphthyridine derivatives
US7767705B2 (en) * 2006-08-25 2010-08-03 Abbott Laboratories Compounds that inhibit TRPV1 and uses thereof
KR20100016593A (ko) 2007-04-16 2010-02-12 그뤼넨탈 게엠베하 신규한 바닐로이드 수용체 리간드 및 약제의 제조를 위한 이의 용도
DE102007018151A1 (de) 2007-04-16 2008-10-23 Günenthal GmbH Neue Vanilloid-Rezeptor Liganden und ihre Verwendung zur Herstellung von Arzneimitteln
JP5478488B2 (ja) 2007-06-20 2014-04-23 メルク・シャープ・アンド・ドーム・コーポレーション Ｊａｎｕｓキナーゼの阻害剤
US8288540B2 (en) 2007-08-22 2012-10-16 Irm Llc 2-heteroarylamino-pyrimidine derivatives as kinase inhibitors
AU2010215261A1 (en) 2009-02-17 2011-09-08 Chiesi Farmaceutici S.P.A. Triazolopyridine derivatives as p38 MAP kinase inhibitors
EP2241557A1 (de) 2009-04-02 2010-10-20 Æterna Zentaris GmbH Chinoxalin-Derivate und deren Anwendung zur Behandlung gutartiger und bösartiger Tumorerkrankungen
SI2427436T1 (sl) 2009-05-07 2013-04-30 Grunenthal Gmbh Substituirani aromatski karboksamidni in sečninski derivati kot ligandi vaniloidnega receptorja
NZ595759A (en) 2009-05-07 2014-03-28 Gruenenthal Chemie Substituted phenylureas and phenylamides as vanilloid receptor ligands
CN102471276A (zh) 2009-08-28 2012-05-23 第一三共株式会社 新型四氢异喹啉化合物

Also Published As

Publication number Publication date
AU2012289254A1 (en) 2014-03-13
CA2842976A1 (en) 2013-01-31
JP2014521617A (ja) 2014-08-28
WO2013013816A1 (en) 2013-01-31
EP2736899A1 (en) 2014-06-04
US20130029995A1 (en) 2013-01-31
US9029378B2 (en) 2015-05-12
KR20140049028A (ko) 2014-04-24
BR112014001714A2 (pt) 2017-02-14

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