MX2014000964A - Derivados aza heterociclicos sustituidos. - Google Patents
Derivados aza heterociclicos sustituidos.Info
- Publication number
- MX2014000964A MX2014000964A MX2014000964A MX2014000964A MX2014000964A MX 2014000964 A MX2014000964 A MX 2014000964A MX 2014000964 A MX2014000964 A MX 2014000964A MX 2014000964 A MX2014000964 A MX 2014000964A MX 2014000964 A MX2014000964 A MX 2014000964A
- Authority
- MX
- Mexico
- Prior art keywords
- substituted heterocyclic
- aza derivatives
- heterocyclic aza
- compounds
- derivatives
- Prior art date
Links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/40—Acylated substituent nitrogen atom
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
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- C—CHEMISTRY; METALLURGY
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- C07D—HETEROCYCLIC COMPOUNDS
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- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
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- C07D213/72—Nitrogen atoms
- C07D213/76—Nitrogen atoms to which a second hetero atom is attached
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- C07D213/81—Amides; Imides
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- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Abstract
La invención se relaciona con derivados aza heterocíclicos como ligandos de receptor vainilloide, con composiciones farmacéuticas que contienen estos compuestos y también estos compuestos para uso en el tratamiento y/o profilaxis de dolor y enfermedades y/o trastornos adicionales.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP11006115 | 2011-07-26 | ||
PCT/EP2012/003138 WO2013013817A1 (en) | 2011-07-26 | 2012-07-25 | Substituted heterocyclic aza derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2014000964A true MX2014000964A (es) | 2014-03-27 |
Family
ID=46642463
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2014000964A MX2014000964A (es) | 2011-07-26 | 2012-07-25 | Derivados aza heterociclicos sustituidos. |
Country Status (10)
Country | Link |
---|---|
US (1) | US20130029961A1 (es) |
EP (1) | EP2736882A1 (es) |
JP (1) | JP2014521618A (es) |
KR (1) | KR20140049027A (es) |
AR (1) | AR087302A1 (es) |
AU (1) | AU2012289255A1 (es) |
BR (1) | BR112014001908A2 (es) |
CA (1) | CA2842983A1 (es) |
MX (1) | MX2014000964A (es) |
WO (1) | WO2013013817A1 (es) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2016082930A1 (en) | 2014-11-24 | 2016-06-02 | Grünenthal GmbH | Substituted oxazole- and thiazole-based carboxamide and urea derivatives as vanilloid receptor ligands ii |
US20180194769A1 (en) | 2015-07-06 | 2018-07-12 | Rodin Therapeutics, Inc. | Hetero-halo inhibitors of histone deacetylase |
EP3319968A1 (en) | 2015-07-06 | 2018-05-16 | Rodin Therapeutics, Inc. | Heterobicyclic n-aminophenyl-amides as inhibitors of histone deacetylase |
EP3130590A1 (en) | 2015-08-13 | 2017-02-15 | Grünenthal GmbH | Aromatic aza compounds as vr1/trpv1 ligands |
EP3130589A1 (en) | 2015-08-13 | 2017-02-15 | Grünenthal GmbH | Heterocyclic aza compounds |
EP3404020B1 (en) * | 2016-01-14 | 2022-11-30 | Research Cooperation Foundation of Yeungnam University | Pyridinol derivative or pharmaceutically acceptable salt thereof, and pharmaceutical composition containing same as active ingredient |
US10793567B2 (en) | 2017-01-11 | 2020-10-06 | Rodin Therapeutics, Inc. | Bicyclic inhibitors of histone deacetylase |
EP3664802B1 (en) | 2017-08-07 | 2022-02-23 | Alkermes, Inc. | Bicyclic inhibitors of histone deacetylase |
CN108997202A (zh) * | 2018-07-10 | 2018-12-14 | 湖南华腾制药有限公司 | 一种(5-三氟甲基-吡啶-2-基)-乙酸盐的制备方法 |
JP7319395B2 (ja) * | 2019-06-14 | 2023-08-01 | ディスアーム セラピューティクス, インコーポレイテッド | Sarm1の阻害剤 |
US20230010258A1 (en) * | 2019-10-31 | 2023-01-12 | Checkmate Therapeutics Inc. | Composition for preventing or inhibiting axonal degeneration |
WO2022030589A1 (ja) * | 2020-08-05 | 2022-02-10 | 国立大学法人北海道大学 | 単座配位尿素化合物を含む配位子とそれを含むホウ素化触媒 |
Family Cites Families (4)
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NZ593684A (en) | 2005-10-19 | 2012-11-30 | Gruenenthal Chemie | Novel vanilloid receptor ligands and their use for producing medicaments |
DE102007018151A1 (de) | 2007-04-16 | 2008-10-23 | Günenthal GmbH | Neue Vanilloid-Rezeptor Liganden und ihre Verwendung zur Herstellung von Arzneimitteln |
KR20100016593A (ko) | 2007-04-16 | 2010-02-12 | 그뤼넨탈 게엠베하 | 신규한 바닐로이드 수용체 리간드 및 약제의 제조를 위한 이의 용도 |
PE20140836A1 (es) * | 2011-07-26 | 2014-08-03 | Gruenenthal Chemie | Derivados de carboxamida y urea que contienen pirazol heteroaromatico sustituido como ligandos del receptor de vanilloide |
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2012
- 2012-07-25 AU AU2012289255A patent/AU2012289255A1/en not_active Abandoned
- 2012-07-25 EP EP12745773.7A patent/EP2736882A1/en not_active Withdrawn
- 2012-07-25 CA CA2842983A patent/CA2842983A1/en not_active Abandoned
- 2012-07-25 MX MX2014000964A patent/MX2014000964A/es unknown
- 2012-07-25 JP JP2014521986A patent/JP2014521618A/ja not_active Withdrawn
- 2012-07-25 AR ARP120102685A patent/AR087302A1/es unknown
- 2012-07-25 US US13/557,773 patent/US20130029961A1/en not_active Abandoned
- 2012-07-25 BR BR112014001908A patent/BR112014001908A2/pt not_active IP Right Cessation
- 2012-07-25 KR KR1020147004941A patent/KR20140049027A/ko not_active Application Discontinuation
- 2012-07-25 WO PCT/EP2012/003138 patent/WO2013013817A1/en active Application Filing
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AU2012289255A1 (en) | 2014-01-30 |
JP2014521618A (ja) | 2014-08-28 |
CA2842983A1 (en) | 2013-01-31 |
AR087302A1 (es) | 2014-03-12 |
EP2736882A1 (en) | 2014-06-04 |
WO2013013817A1 (en) | 2013-01-31 |
BR112014001908A2 (pt) | 2017-02-21 |
KR20140049027A (ko) | 2014-04-24 |
US20130029961A1 (en) | 2013-01-31 |
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