MA35285B1 - Indazoles - Google Patents

Indazoles

Info

Publication number
MA35285B1
MA35285B1 MA36716A MA36716A MA35285B1 MA 35285 B1 MA35285 B1 MA 35285B1 MA 36716 A MA36716 A MA 36716A MA 36716 A MA36716 A MA 36716A MA 35285 B1 MA35285 B1 MA 35285B1
Authority
MA
Morocco
Prior art keywords
compounds
pharmaceutically acceptable
well
relates
salts
Prior art date
Application number
MA36716A
Other languages
English (en)
Inventor
Jotham Wadsworth Coe
Christoph Martin Dehnhardt
Peter Jones
Steven Wade Kortum
Yogesh Anil Sabnis
Florian Michel Wakenhut
Gavin Alistair Whitlock
Original Assignee
Pfizer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46826868&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA35285(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer Ltd filed Critical Pfizer Ltd
Publication of MA35285B1 publication Critical patent/MA35285B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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    • A—HUMAN NECESSITIES
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Communicable Diseases (AREA)
  • Endocrinology (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Reproductive Health (AREA)
  • Toxicology (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Psychiatry (AREA)
  • Child & Adolescent Psychology (AREA)

Abstract

L'invention concerne des composés de formule (i), des sels pharmaceutiquement acceptables de ceux-ci, ainsi que des solvates pharmaceutiquement acceptables de ces composés et sels, dont les substituants sont tels que définis dans la description. L'invention concerne également des compositions contenant ces composés, ainsi que les utilisations de ces composés dans le traitement de diverses maladies, en particulier l'asthme et la maladie pulmonaire obstructive chronique (mpoc).
MA36716A 2011-07-27 2014-01-27 Indazoles MA35285B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161512144P 2011-07-27 2011-07-27
PCT/IB2012/053546 WO2013014567A1 (fr) 2011-07-27 2012-07-11 Indazoles

Publications (1)

Publication Number Publication Date
MA35285B1 true MA35285B1 (fr) 2014-07-03

Family

ID=46826868

Family Applications (1)

Application Number Title Priority Date Filing Date
MA36716A MA35285B1 (fr) 2011-07-27 2014-01-27 Indazoles

Country Status (30)

Country Link
US (2) US8575336B2 (fr)
EP (1) EP2736907B1 (fr)
JP (1) JP5579351B1 (fr)
KR (1) KR20140026627A (fr)
CN (1) CN103717599B (fr)
AP (1) AP2014007372A0 (fr)
AR (1) AR087348A1 (fr)
AU (1) AU2012288491A1 (fr)
BR (1) BR112014001801A2 (fr)
CA (1) CA2841882A1 (fr)
CL (1) CL2014000122A1 (fr)
CO (1) CO6862160A2 (fr)
CR (1) CR20140042A (fr)
CU (1) CU20140009A7 (fr)
DO (1) DOP2014000016A (fr)
EA (1) EA201490357A1 (fr)
EC (1) ECSP14013222A (fr)
GT (1) GT201400016A (fr)
IL (1) IL230662A0 (fr)
MA (1) MA35285B1 (fr)
MD (1) MD20140002A2 (fr)
MX (1) MX2014001004A (fr)
NI (1) NI201400005A (fr)
PE (1) PE20141059A1 (fr)
PH (1) PH12014500199A1 (fr)
TN (1) TN2014000033A1 (fr)
TW (1) TWI462922B (fr)
UA (1) UA108442C2 (fr)
UY (1) UY34220A (fr)
WO (1) WO2013014567A1 (fr)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8575336B2 (en) 2011-07-27 2013-11-05 Pfizer Limited Indazoles
EP3143021B1 (fr) * 2014-05-14 2019-06-12 Pfizer Inc Pyrazolopyridines et pyrazolopyrimidines
WO2016139212A1 (fr) 2015-03-04 2016-09-09 F. Hoffmann-La Roche Ag Composés de triazolopyridine, et procédés d'utilisation de ceux-ci
SG11201707752SA (en) 2015-04-22 2017-11-29 Rigel Pharmaceuticals Inc Pyrazole compounds and method for making and using the compounds
EP3371184A1 (fr) 2015-11-03 2018-09-12 Topivert Pharma Limited Dérivés 4,5,6,7-tétrahydro-1h-imidazo[4,5-c]pyridine et 1,4,5,6,7,8-héxahydroimidazo[4,5-d]azépine en tant qu'inhibiteurs de janus kinase
KR20180073687A (ko) 2015-11-03 2018-07-02 세라밴스 바이오파마 알앤디 아이피, 엘엘씨 호흡기 질환의 치료를 위한 jak 키나제 저해제 화합물
ES2840650T3 (es) 2015-11-03 2021-07-07 Topivert Pharma Ltd Derivados de 4,5,6,7-tetrahidro-1h-imidazo[4,5-c]piridina y 1,4,5,6,7,8-hexahidroimidazo[4,5-d]azepina como inhibidores de la quinasa janus
TW201720828A (zh) 2015-11-23 2017-06-16 赫孚孟拉羅股份公司 治療性化合物及組合物以及其使用方法
WO2017096262A1 (fr) 2015-12-04 2017-06-08 Jomoco, Corp. Compositions et procédés pour atténuer ou prévenir une réponse immunitaire à une molécule thérapeutique immunogène chez des primates non humains
EP3416967B1 (fr) 2016-02-18 2022-02-09 F. Hoffmann-La Roche AG Composés thérapeutiques, leurs compositions et méthodes d'utilisation
WO2017191098A1 (fr) 2016-05-05 2017-11-09 F. Hoffmann-La Roche Ag Dérivés de pyrazole, compositions les comprenant et leur utilisation thérapeutique
RU2743170C2 (ru) * 2016-06-01 2021-02-15 Байер Энимал Хелс Гмбх Замещенные индазолы, пригодные для лечения и предупреждения аллергических и/или воспалительных заболеваний у животных
JP7050761B2 (ja) 2016-09-06 2022-04-08 エフ．ホフマン－ラ ロシュ アーゲー ８－（アゼチジン－１－イル）－［１，２，４］トリアゾロ［１，５－ａ］ピリジニル化合物、組成物及びその使用方法
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