UA108442C2 - Индазолы - Google Patents

Индазолы

Info

Publication number
UA108442C2
UA108442C2 UAA201400660A UAA201400660A UA108442C2 UA 108442 C2 UA108442 C2 UA 108442C2 UA A201400660 A UAA201400660 A UA A201400660A UA A201400660 A UAA201400660 A UA A201400660A UA 108442 C2 UA108442 C2 UA 108442C2
Authority
UA
Ukraine
Prior art keywords
compounds
pharmaceutically acceptable
salts
indazol
copd
Prior art date
Application number
UAA201400660A
Other languages
English (en)
Ukrainian (uk)
Inventor
Джонатан Уодсворт Ко
Крістоф Мартін Денхардт
Пітер Джонс
Стівен Уейд Кортум
Йогеш Еніл Сабніс
Флоріан Майкл Вакенхут
Гейвін Алістер Вайтлок
Original Assignee
Пфайзер Лімітед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46826868&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA108442(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Пфайзер Лімітед filed Critical Пфайзер Лімітед
Publication of UA108442C2 publication Critical patent/UA108442C2/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Toxicology (AREA)
  • Reproductive Health (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Gynecology & Obstetrics (AREA)
  • Transplantation (AREA)

Abstract

Настоящее изобретение касается соединений формулы (I) EMBED ISISServer    (I) их фармацевтически приемлемых солей и фармацевтически приемлемых сольватов упомянутых соединений и солей, где заместители определены в этом документе; композиций, содержащих такие соединения; и использование таких соединений в лечении различных заболеваний, в частности астмы и ХОБЛ.
UAA201400660A 2011-07-27 2012-07-11 Индазолы UA108442C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161512144P 2011-07-27 2011-07-27
PCT/IB2012/053546 WO2013014567A1 (en) 2011-07-27 2012-07-11 Indazoles

Publications (1)

Publication Number Publication Date
UA108442C2 true UA108442C2 (ru) 2015-04-27

Family

ID=46826868

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201400660A UA108442C2 (ru) 2011-07-27 2012-07-11 Индазолы

Country Status (29)

Country Link
US (2) US8575336B2 (ru)
EP (1) EP2736907B1 (ru)
JP (1) JP5579351B1 (ru)
KR (1) KR20140026627A (ru)
CN (1) CN103717599B (ru)
AP (1) AP2014007372A0 (ru)
AR (1) AR087348A1 (ru)
AU (1) AU2012288491A1 (ru)
BR (1) BR112014001801A2 (ru)
CA (1) CA2841882A1 (ru)
CL (1) CL2014000122A1 (ru)
CO (1) CO6862160A2 (ru)
CR (1) CR20140042A (ru)
CU (1) CU20140009A7 (ru)
DO (1) DOP2014000016A (ru)
EA (1) EA201490357A1 (ru)
EC (1) ECSP14013222A (ru)
GT (1) GT201400016A (ru)
IL (1) IL230662A0 (ru)
MA (1) MA35285B1 (ru)
MD (1) MD20140002A2 (ru)
MX (1) MX2014001004A (ru)
NI (1) NI201400005A (ru)
PE (1) PE20141059A1 (ru)
TN (1) TN2014000033A1 (ru)
TW (1) TWI462922B (ru)
UA (1) UA108442C2 (ru)
UY (1) UY34220A (ru)
WO (1) WO2013014567A1 (ru)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8575336B2 (en) 2011-07-27 2013-11-05 Pfizer Limited Indazoles
KR20170002623A (ko) 2014-05-14 2017-01-06 화이자 인코포레이티드 피라졸로피리딘 및 피라졸로피리미딘
JP2018507236A (ja) 2015-03-04 2018-03-15 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ トリアゾロピリジン化合物及びその使用法
SG11201707752SA (en) 2015-04-22 2017-11-29 Rigel Pharmaceuticals Inc Pyrazole compounds and method for making and using the compounds
PT3371185T (pt) * 2015-11-03 2020-12-28 Topivert Pharma Ltd Derivados de 4,5,6,7-tetrahidro-1h-imidazo[4,5-c]piridina e 1,4,5,6,7,8-hexahidroimidazo[4,5-d]azepina como inibidores de janus quinase
WO2017077283A1 (en) * 2015-11-03 2017-05-11 Topivert Pharma Limited 4,5,6,7-tetrahydro-1h-imidazo[4,5-c]pyridine and 1,4,5,6,7,8-hexahydroimidazo[4,5-d]azepine derivatives as janus kinase inhibitors
CA3001542C (en) 2015-11-03 2021-02-16 Theravance Biopharma R&D Ip, Llc Jak kinase inhibitor compounds for treatment of respiratory disease
TW201720828A (zh) 2015-11-23 2017-06-16 赫孚孟拉羅股份公司 治療性化合物及組合物以及其使用方法
WO2017096262A1 (en) 2015-12-04 2017-06-08 Jomoco, Corp. Compositions and methods to mitigate or prevent an immune response to an immunogenic therapeutic molecule in non-human primates
CN108473501B (zh) 2016-02-18 2021-07-16 豪夫迈·罗氏有限公司 治疗化合物、其组合物及使用方法
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