TN2014000033A1 - Indazoles - Google Patents

Indazoles

Info

Publication number
TN2014000033A1
TN2014000033A1 TNP2014000033A TN2014000033A TN2014000033A1 TN 2014000033 A1 TN2014000033 A1 TN 2014000033A1 TN P2014000033 A TNP2014000033 A TN P2014000033A TN 2014000033 A TN2014000033 A TN 2014000033A TN 2014000033 A1 TN2014000033 A1 TN 2014000033A1
Authority
TN
Tunisia
Prior art keywords
compounds
pharmaceutically acceptable
salts
indazoles
copd
Prior art date
Application number
TNP2014000033A
Other languages
English (en)
Inventor
Jotham Wadsworth Coe
Christoph Martin Dehnhardt
Peter Jones
Steven Wade Kortum
Yogesh Anil Sabnis
Florian Michel Wakenhut
Gavin Alistair Whitlock
Original Assignee
Pfizer Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46826868&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TN2014000033(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer Ltd filed Critical Pfizer Ltd
Publication of TN2014000033A1 publication Critical patent/TN2014000033A1/fr

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurosurgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Toxicology (AREA)
  • Obesity (AREA)
  • Hospice & Palliative Care (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Child & Adolescent Psychology (AREA)

Abstract

La présente invention concerne des composés de formule (I), leurs sels pharmaceutiquement acceptables et les produits de solvatation pharmaceutiquement acceptables desdits composés et sels, dans lesquels les substituants répondent aux définitions figurants dans le présent mémoire ; des compositions contenant ces composés ; et les utilisations de ces composés dans le traitement de diverses maladies, en particulier l'asthme et la maladie pulmonaire obstructive chronique (COPD)
TNP2014000033A 2011-07-27 2014-01-21 Indazoles TN2014000033A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161512144P 2011-07-27 2011-07-27
PCT/IB2012/053546 WO2013014567A1 (fr) 2011-07-27 2012-07-11 Indazoles

Publications (1)

Publication Number Publication Date
TN2014000033A1 true TN2014000033A1 (fr) 2015-07-01

Family

ID=46826868

Family Applications (1)

Application Number Title Priority Date Filing Date
TNP2014000033A TN2014000033A1 (fr) 2011-07-27 2014-01-21 Indazoles

Country Status (29)

Country Link
US (2) US8575336B2 (fr)
EP (1) EP2736907B1 (fr)
JP (1) JP5579351B1 (fr)
KR (1) KR20140026627A (fr)
CN (1) CN103717599B (fr)
AP (1) AP2014007372A0 (fr)
AR (1) AR087348A1 (fr)
AU (1) AU2012288491A1 (fr)
BR (1) BR112014001801A2 (fr)
CA (1) CA2841882A1 (fr)
CL (1) CL2014000122A1 (fr)
CO (1) CO6862160A2 (fr)
CR (1) CR20140042A (fr)
CU (1) CU20140009A7 (fr)
DO (1) DOP2014000016A (fr)
EA (1) EA201490357A1 (fr)
EC (1) ECSP14013222A (fr)
GT (1) GT201400016A (fr)
IL (1) IL230662A0 (fr)
MA (1) MA35285B1 (fr)
MD (1) MD20140002A2 (fr)
MX (1) MX2014001004A (fr)
NI (1) NI201400005A (fr)
PE (1) PE20141059A1 (fr)
TN (1) TN2014000033A1 (fr)
TW (1) TWI462922B (fr)
UA (1) UA108442C2 (fr)
UY (1) UY34220A (fr)
WO (1) WO2013014567A1 (fr)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8575336B2 (en) 2011-07-27 2013-11-05 Pfizer Limited Indazoles
WO2015173683A1 (fr) 2014-05-14 2015-11-19 Pfizer Inc. Pyrazolopyridines et pyrazolopyrimidines
JP2018507236A (ja) 2015-03-04 2018-03-15 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ トリアゾロピリジン化合物及びその使用法
EP3286181B1 (fr) 2015-04-22 2021-01-27 Rigel Pharmaceuticals, Inc. Composés de pyrazole et procédé de fabrication et d'utilisation de ces composés
EP3865481A1 (fr) 2015-11-03 2021-08-18 Topivert Pharma Limited Dérivés de 4,5,6,7-tétrahydro-1h-imidazo[4,5-c]pyridine et 1,4,5,6,7,8-hexahydroimidazo[4,5-d]azépine à utiliser en tant qu'inhibiteurs de janus kinase
EP3371185B1 (fr) 2015-11-03 2020-09-30 Topivert Pharma Limited Dérivés de 4,5,6,7-tétrahydro-1h-imidazo[4,5-c]pyridine et 1,4,5,6,7,8-hexahydroimidazo[4,5-d]azépine à utiliser en tant qu'inhibiteurs de janus kinase
US10100049B2 (en) * 2015-11-03 2018-10-16 Theravance Biopharma R&D Ip, Llc JAK kinase inhibitor compounds for treatment of respiratory disease
TW201720828A (zh) 2015-11-23 2017-06-16 赫孚孟拉羅股份公司 治療性化合物及組合物以及其使用方法
US20170157215A1 (en) 2015-12-04 2017-06-08 Jomoco, Corp. Compositions and methods to mitigate or prevent an immune response to an immunogenic therapeutic molecule in non-human primates
JP6936236B2 (ja) 2016-02-18 2021-09-15 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 治療化合物、組成物及びその方法の使用
EP3452464B1 (fr) 2016-05-05 2021-12-15 F. Hoffmann-La Roche AG Dérivés de la pyrazole et leur utilisations therapeutique
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