CL2014000122A1 - Compuestos derivados de indazol, inhibidores de janus quinasa (jak); composicion farmaceutica que los comprende; y su uso para tratar rinitis alergica, congestion nasal, asma, bronquitis cronica, artritis, insuficiencia cardiaca, colitis ulcerativa, infeccion viral y bacteriana, cancer y alzheimer, entre otras enfermedades. - Google Patents
Compuestos derivados de indazol, inhibidores de janus quinasa (jak); composicion farmaceutica que los comprende; y su uso para tratar rinitis alergica, congestion nasal, asma, bronquitis cronica, artritis, insuficiencia cardiaca, colitis ulcerativa, infeccion viral y bacteriana, cancer y alzheimer, entre otras enfermedades.Info
- Publication number
- CL2014000122A1 CL2014000122A1 CL2014000122A CL2014000122A CL2014000122A1 CL 2014000122 A1 CL2014000122 A1 CL 2014000122A1 CL 2014000122 A CL2014000122 A CL 2014000122A CL 2014000122 A CL2014000122 A CL 2014000122A CL 2014000122 A1 CL2014000122 A1 CL 2014000122A1
- Authority
- CL
- Chile
- Prior art keywords
- jak
- indazole
- alzheimer
- asthma
- arthritis
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
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- Public Health (AREA)
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- Orthopedic Medicine & Surgery (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Dermatology (AREA)
- Neurosurgery (AREA)
- Ophthalmology & Optometry (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Toxicology (AREA)
- Obesity (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161512144P | 2011-07-27 | 2011-07-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
CL2014000122A1 true CL2014000122A1 (es) | 2014-08-18 |
Family
ID=46826868
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CL2014000122A CL2014000122A1 (es) | 2011-07-27 | 2014-01-16 | Compuestos derivados de indazol, inhibidores de janus quinasa (jak); composicion farmaceutica que los comprende; y su uso para tratar rinitis alergica, congestion nasal, asma, bronquitis cronica, artritis, insuficiencia cardiaca, colitis ulcerativa, infeccion viral y bacteriana, cancer y alzheimer, entre otras enfermedades. |
Country Status (29)
Country | Link |
---|---|
US (2) | US8575336B2 (es) |
EP (1) | EP2736907B1 (es) |
JP (1) | JP5579351B1 (es) |
KR (1) | KR20140026627A (es) |
CN (1) | CN103717599B (es) |
AP (1) | AP2014007372A0 (es) |
AR (1) | AR087348A1 (es) |
AU (1) | AU2012288491A1 (es) |
BR (1) | BR112014001801A2 (es) |
CA (1) | CA2841882A1 (es) |
CL (1) | CL2014000122A1 (es) |
CO (1) | CO6862160A2 (es) |
CR (1) | CR20140042A (es) |
CU (1) | CU20140009A7 (es) |
DO (1) | DOP2014000016A (es) |
EA (1) | EA201490357A1 (es) |
EC (1) | ECSP14013222A (es) |
GT (1) | GT201400016A (es) |
IL (1) | IL230662A0 (es) |
MA (1) | MA35285B1 (es) |
MD (1) | MD20140002A2 (es) |
MX (1) | MX2014001004A (es) |
NI (1) | NI201400005A (es) |
PE (1) | PE20141059A1 (es) |
TN (1) | TN2014000033A1 (es) |
TW (1) | TWI462922B (es) |
UA (1) | UA108442C2 (es) |
UY (1) | UY34220A (es) |
WO (1) | WO2013014567A1 (es) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11629148B2 (en) | 2019-02-25 | 2023-04-18 | Henan Medinno Pharmaceutical Technology Co., Ltd. | Substituted pyrrolo[3,4-d]imidazoles as JAK inhibitors |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8575336B2 (en) | 2011-07-27 | 2013-11-05 | Pfizer Limited | Indazoles |
AU2015260905A1 (en) | 2014-05-14 | 2016-12-01 | Pfizer Inc. | Pyrazolopyridines and pyrazolopyrimidines |
JP2018507236A (ja) | 2015-03-04 | 2018-03-15 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | トリアゾロピリジン化合物及びその使用法 |
EA039043B1 (ru) | 2015-04-22 | 2021-11-25 | Райджел Фармасьютикалз, Инк. | Пиразольные соединения и способ получения и применения данных соединений |
CA3001542C (en) | 2015-11-03 | 2021-02-16 | Theravance Biopharma R&D Ip, Llc | Jak kinase inhibitor compounds for treatment of respiratory disease |
US10556901B2 (en) | 2015-11-03 | 2020-02-11 | Topivert Pharma Limited | 4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine and 1,4,5,6,7,8-hexahydroimidazo[4,5-d]azepine derivatives as Janus kinase inhibitors |
WO2017077283A1 (en) * | 2015-11-03 | 2017-05-11 | Topivert Pharma Limited | 4,5,6,7-tetrahydro-1h-imidazo[4,5-c]pyridine and 1,4,5,6,7,8-hexahydroimidazo[4,5-d]azepine derivatives as janus kinase inhibitors |
TW201720828A (zh) | 2015-11-23 | 2017-06-16 | 赫孚孟拉羅股份公司 | 治療性化合物及組合物以及其使用方法 |
US20170157215A1 (en) | 2015-12-04 | 2017-06-08 | Jomoco, Corp. | Compositions and methods to mitigate or prevent an immune response to an immunogenic therapeutic molecule in non-human primates |
WO2017140825A1 (en) | 2016-02-18 | 2017-08-24 | F. Hoffmann-La Roche Ag | Therapeutic compounds, compositions and methods of use thereof |
CN109476638B (zh) | 2016-05-05 | 2021-12-28 | 豪夫迈·罗氏有限公司 | 吡唑衍生物、其组合物及治疗用途 |
AU2017272505B9 (en) * | 2016-06-01 | 2021-10-28 | Bayer Animal Health Gmbh | Substituted indazoles useful for treatment and prevention of allergic and/or inflammatory diseases in animals |
MX2019002627A (es) | 2016-09-06 | 2019-10-30 | Hoffmann La Roche | Compuestos de 8-(azetidin-1-il)-[1,2,4]triazolo[1,5-a]piridinilo, composiciones y métodos de uso del mismo. |
AU2017385543A1 (en) | 2016-12-29 | 2019-05-23 | F. Hoffmann-La Roche Ag | Pyrazolopyrimidine compounds and methods of use thereof |
PT3592742T (pt) * | 2017-03-09 | 2021-07-30 | Theravance Biopharma R&D Ip Llc | Inibidores de jak contendo uma amida heterocíclica com 4 membros |
CN110494434B (zh) | 2017-03-14 | 2022-05-24 | 豪夫迈·罗氏有限公司 | 吡唑并氯苯基化合物、其组合物及其使用方法 |
AR111495A1 (es) * | 2017-05-01 | 2019-07-17 | Theravance Biopharma R&D Ip Llc | Compuestos de imidazo-piperidina fusionada como inhibidores de jak |
SG11201909376TA (en) * | 2017-05-01 | 2019-11-28 | Theravance Biopharma R&D Ip Llc | Crystalline forms of a jak inhibitor compound |
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US11629148B2 (en) | 2019-02-25 | 2023-04-18 | Henan Medinno Pharmaceutical Technology Co., Ltd. | Substituted pyrrolo[3,4-d]imidazoles as JAK inhibitors |
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