PL2464232T3 - Indazolowe inhibitory szlaku sygnałowego Wnt i ich zastosowania terapeutyczne - Google Patents

Indazolowe inhibitory szlaku sygnałowego Wnt i ich zastosowania terapeutyczne

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Publication number
PL2464232T3
PL2464232T3 PL10808589T PL10808589T PL2464232T3 PL 2464232 T3 PL2464232 T3 PL 2464232T3 PL 10808589 T PL10808589 T PL 10808589T PL 10808589 T PL10808589 T PL 10808589T PL 2464232 T3 PL2464232 T3 PL 2464232T3
Authority
PL
Poland
Prior art keywords
therapeutic uses
signal pathway
wnt signal
indazole inhibitors
indazole
Prior art date
Application number
PL10808589T
Other languages
English (en)
Inventor
John Hood
David Mark Wallace
Sunil Kumar Kc
Original Assignee
Samumed Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Samumed Llc filed Critical Samumed Llc
Publication of PL2464232T3 publication Critical patent/PL2464232T3/pl

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    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
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    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
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    • A61K31/4151,2-Diazoles
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