MX2009002999A - Analogos de insulina resistentes a proteasa. - Google Patents

Analogos de insulina resistentes a proteasa.

Info

Publication number
MX2009002999A
MX2009002999A MX2009002999A MX2009002999A MX2009002999A MX 2009002999 A MX2009002999 A MX 2009002999A MX 2009002999 A MX2009002999 A MX 2009002999A MX 2009002999 A MX2009002999 A MX 2009002999A MX 2009002999 A MX2009002999 A MX 2009002999A
Authority
MX
Mexico
Prior art keywords
insulin analogues
insulin
protease resistant
analogues
resistant insulin
Prior art date
Application number
MX2009002999A
Other languages
English (en)
Inventor
Svend Havelund
Per Balschmidt
Svend Ludvigsen
Ulla Ribel-Madsen
Frantisek Hubalek
Peter Kresten Nielsen
Inger Lautrup-Larsen
Per Noergaard
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38754488&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2009002999(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of MX2009002999A publication Critical patent/MX2009002999A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)

Abstract

La presente invención se relaciona con análogos de insulina novedosos que exhiben resistencia hacia la proteasa, en donde al menos dos aminoácidos están sustituidos y/o suprimidos con relación a la molécula de insulina progenitora. También se proporciona un método para el tratamiento de estos análogos de insulina, las preparaciones de insulina que contienen los análogos de insulina de la invención y un método de tratamiento de diabetes mellitus usando estos análogos de insulina.
MX2009002999A 2006-09-22 2007-09-20 Analogos de insulina resistentes a proteasa. MX2009002999A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06121113 2006-09-22
PCT/EP2007/059990 WO2008034881A1 (en) 2006-09-22 2007-09-20 Protease resistant insulin analogues

Publications (1)

Publication Number Publication Date
MX2009002999A true MX2009002999A (es) 2009-04-01

Family

ID=38754488

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009002999A MX2009002999A (es) 2006-09-22 2007-09-20 Analogos de insulina resistentes a proteasa.

Country Status (20)

Country Link
US (1) US9018161B2 (es)
EP (2) EP2404934A1 (es)
JP (2) JP5864834B2 (es)
KR (2) KR101699370B1 (es)
CN (1) CN101541830A (es)
AU (1) AU2007298919C1 (es)
BR (1) BRPI0717098B8 (es)
CA (1) CA2663074A1 (es)
DK (1) DK2074141T3 (es)
ES (1) ES2601839T3 (es)
HU (1) HUE029512T2 (es)
IL (1) IL197609A (es)
MX (1) MX2009002999A (es)
NO (1) NO20091563L (es)
PL (1) PL2074141T3 (es)
PT (1) PT2074141T (es)
RU (1) RU2524150C2 (es)
TW (1) TW200829600A (es)
WO (1) WO2008034881A1 (es)
ZA (1) ZA200901838B (es)

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