CO4970787A1 - Composiciones insolubles de insulina y derivados de insulina que controlan la glucosa sanguinea - Google Patents

Composiciones insolubles de insulina y derivados de insulina que controlan la glucosa sanguinea

Info

Publication number
CO4970787A1
CO4970787A1 CO98075716A CO98075716A CO4970787A1 CO 4970787 A1 CO4970787 A1 CO 4970787A1 CO 98075716 A CO98075716 A CO 98075716A CO 98075716 A CO98075716 A CO 98075716A CO 4970787 A1 CO4970787 A1 CO 4970787A1
Authority
CO
Colombia
Prior art keywords
insulin
blood glucose
control blood
insoluble compositions
derivatives
Prior art date
Application number
CO98075716A
Other languages
English (en)
Inventor
Mark Laurence Brader
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of CO4970787A1 publication Critical patent/CO4970787A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin

Abstract

Una composición insoluble constituida por: a) una proteína seleccionada del grupo conformado por insulina, análogo de la insulina, y proinsulina; b) una proteína derivatizada seleccionada del grupo conformado por insulina derivatizada, análogo de insulina denvatizada, y proinsulina derivatizada; c) un compuesto complejante; d) un compuesto estabilizante de hexámeros; y e) un catión de metal divalente.
CO98075716A 1997-12-23 1998-12-21 Composiciones insolubles de insulina y derivados de insulina que controlan la glucosa sanguinea CO4970787A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6860197P 1997-12-23 1997-12-23
US8885998P 1998-06-11 1998-06-11
US10994098P 1998-11-25 1998-11-25

Publications (1)

Publication Number Publication Date
CO4970787A1 true CO4970787A1 (es) 2000-11-07

Family

ID=27371371

Family Applications (1)

Application Number Title Priority Date Filing Date
CO98075716A CO4970787A1 (es) 1997-12-23 1998-12-21 Composiciones insolubles de insulina y derivados de insulina que controlan la glucosa sanguinea

Country Status (24)

Country Link
US (2) US6531448B1 (es)
EP (1) EP0925792B1 (es)
JP (1) JP2001526225A (es)
KR (1) KR20010024799A (es)
CN (1) CN1284876A (es)
AR (1) AR019807A1 (es)
AT (1) ATE264690T1 (es)
AU (1) AU2008899A (es)
BR (1) BR9814471A (es)
CA (1) CA2315300A1 (es)
CO (1) CO4970787A1 (es)
DE (1) DE69823319D1 (es)
DZ (1) DZ2691A1 (es)
EA (1) EA003394B1 (es)
HR (1) HRP20000427A2 (es)
HU (1) HUP0100243A3 (es)
ID (1) ID25476A (es)
IL (1) IL136724A0 (es)
NO (1) NO20003269L (es)
NZ (1) NZ505091A (es)
PE (1) PE20000106A1 (es)
PL (1) PL341300A1 (es)
TR (1) TR200001935T2 (es)
WO (1) WO1999032116A1 (es)

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Also Published As

Publication number Publication date
AU2008899A (en) 1999-07-12
HUP0100243A3 (en) 2001-09-28
EP0925792A2 (en) 1999-06-30
PL341300A1 (en) 2001-04-09
AR019807A1 (es) 2002-03-20
JP2001526225A (ja) 2001-12-18
TR200001935T2 (tr) 2000-12-21
CA2315300A1 (en) 1999-07-01
NO20003269D0 (no) 2000-06-22
HUP0100243A2 (hu) 2001-08-28
DZ2691A1 (fr) 2003-03-29
US6531448B1 (en) 2003-03-11
BR9814471A (pt) 2000-10-10
EA003394B1 (ru) 2003-04-24
HRP20000427A2 (en) 2001-06-30
US20030144181A1 (en) 2003-07-31
EA200000708A1 (ru) 2000-12-25
PE20000106A1 (es) 2000-02-09
NZ505091A (en) 2002-11-26
CN1284876A (zh) 2001-02-21
DE69823319D1 (de) 2004-05-27
EP0925792B1 (en) 2004-04-21
EP0925792A3 (en) 2001-09-12
WO1999032116A1 (en) 1999-07-01
KR20010024799A (ko) 2001-03-26
NO20003269L (no) 2000-08-23
IL136724A0 (en) 2001-06-14
ATE264690T1 (de) 2004-05-15
ID25476A (id) 2000-10-05

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