LV11884B - Ciklosporīna orālās ārstnieciskās formas ar augstu biopieejamību - Google Patents

Ciklosporīna orālās ārstnieciskās formas ar augstu biopieejamību Download PDF

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Publication number
LV11884B
LV11884B LVP-97-94A LV970094A LV11884B LV 11884 B LV11884 B LV 11884B LV 970094 A LV970094 A LV 970094A LV 11884 B LV11884 B LV 11884B
Authority
LV
Latvia
Prior art keywords
cyclosporin
und
weight
solution
ethanol
Prior art date
Application number
LVP-97-94A
Other languages
English (en)
Latvian (lv)
Other versions
LV11884A (lv
Inventor
Matthias Olbrich
Heinrich P�TTER
Original Assignee
Novartis Ag
,
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag, , filed Critical Novartis Ag
Publication of LV11884A publication Critical patent/LV11884A/xx
Publication of LV11884B publication Critical patent/LV11884B/lv

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Transplantation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
LVP-97-94A 1994-11-03 1997-05-14 Ciklosporīna orālās ārstnieciskās formas ar augstu biopieejamību LV11884B (lv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4438861 1994-11-03
PCT/DE1995/000951 WO1996014079A1 (de) 1994-11-03 1995-07-19 Neue zubereitungsformen des cyclosporins zur oralen applikation mit einfacher zusammensetzung und hoher bioverfügbarkeit und verfahren zu deren herstellung

Publications (2)

Publication Number Publication Date
LV11884A LV11884A (lv) 1997-12-20
LV11884B true LV11884B (lv) 1998-03-20

Family

ID=6532126

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-97-94A LV11884B (lv) 1994-11-03 1997-05-14 Ciklosporīna orālās ārstnieciskās formas ar augstu biopieejamību

Country Status (27)

Country Link
US (1) US6486124B2 (ru)
EP (1) EP0789580B1 (ru)
JP (1) JP3833248B2 (ru)
KR (1) KR970704464A (ru)
CN (1) CN1121238C (ru)
AT (1) ATE218359T1 (ru)
AU (1) AU715165B2 (ru)
BG (1) BG62955B1 (ru)
BR (1) BR9509550A (ru)
CA (1) CA2231404C (ru)
CZ (1) CZ287806B6 (ru)
DE (2) DE59510233D1 (ru)
DK (1) DK0789580T3 (ru)
EE (1) EE03425B1 (ru)
ES (1) ES2177652T3 (ru)
FI (1) FI118722B (ru)
HU (1) HUT77283A (ru)
LT (1) LT4306B (ru)
LV (1) LV11884B (ru)
NO (1) NO970741D0 (ru)
PL (1) PL183579B1 (ru)
PT (1) PT789580E (ru)
RU (1) RU2158601C2 (ru)
SK (1) SK164796A3 (ru)
TR (1) TR199501361A2 (ru)
TW (1) TW492876B (ru)
WO (1) WO1996014079A1 (ru)

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RU2158601C2 (ru) 1994-11-03 2000-11-10 Новартис Аг Новые лекарственные формы циклоспорина для орального применения с простым составом и высокой биодоступностью и способ их получения
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Also Published As

Publication number Publication date
EE03425B1 (et) 2001-06-15
TR199501361A2 (tr) 1996-06-21
LT4306B (lt) 1998-03-25
CA2231404A1 (en) 1996-05-17
EE9700112A (et) 1997-12-15
PL183579B1 (pl) 2002-06-28
ATE218359T1 (de) 2002-06-15
CZ361696A3 (en) 1997-07-16
CN1121238C (zh) 2003-09-17
BG62955B1 (bg) 2000-12-29
NO970741L (no) 1997-02-18
RU2158601C2 (ru) 2000-11-10
NO970741D0 (no) 1997-02-18
US6486124B2 (en) 2002-11-26
EP0789580B1 (de) 2002-06-05
WO1996014079A1 (de) 1996-05-17
PT789580E (pt) 2002-09-30
FI970634A0 (fi) 1997-02-14
SK164796A3 (en) 1997-06-04
CZ287806B6 (en) 2001-02-14
DE19539860A1 (de) 1996-05-09
BR9509550A (pt) 1997-09-16
CN1162265A (zh) 1997-10-15
DK0789580T3 (da) 2002-09-09
DE59510233D1 (de) 2002-07-11
PL318560A1 (en) 1997-06-23
LT97002A (en) 1997-11-25
HUT77283A (hu) 1998-03-30
FI118722B (fi) 2008-02-29
LV11884A (lv) 1997-12-20
AU715165B2 (en) 2000-01-20
KR970704464A (ko) 1997-09-06
EP0789580A1 (de) 1997-08-20
JPH10508306A (ja) 1998-08-18
AU2975195A (en) 1996-05-31
BG101117A (en) 1997-08-29
JP3833248B2 (ja) 2006-10-11
ES2177652T3 (es) 2002-12-16
CA2231404C (en) 2009-02-17
US20020025927A1 (en) 2002-02-28
TW492876B (en) 2002-07-01
FI970634A (fi) 1997-02-14

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