LV11884A - Ciklosporina oralas arstnieciskas formas ar augstu biopieejamibu - Google Patents

Ciklosporina oralas arstnieciskas formas ar augstu biopieejamibu

Info

Publication number
LV11884A
LV11884A LV970094A LV970094A LV11884A LV 11884 A LV11884 A LV 11884A LV 970094 A LV970094 A LV 970094A LV 970094 A LV970094 A LV 970094A LV 11884 A LV11884 A LV 11884A
Authority
LV
Latvia
Prior art keywords
cyclosporin
weight
high bioavailability
solvent
oralas
Prior art date
Application number
LV970094A
Other languages
English (en)
Other versions
LV11884B (lv
Inventor
Matthias Olbrich
Heinrich Poetter
Original Assignee
Dresden Arzneimittel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dresden Arzneimittel filed Critical Dresden Arzneimittel
Publication of LV11884A publication Critical patent/LV11884A/lv
Publication of LV11884B publication Critical patent/LV11884B/lv

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Transplantation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
LVP-97-94A 1994-11-03 1997-05-14 Ciklosporīna orālās ārstnieciskās formas ar augstu biopieejamību LV11884B (lv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4438861 1994-11-03
PCT/DE1995/000951 WO1996014079A1 (de) 1994-11-03 1995-07-19 Neue zubereitungsformen des cyclosporins zur oralen applikation mit einfacher zusammensetzung und hoher bioverfügbarkeit und verfahren zu deren herstellung

Publications (2)

Publication Number Publication Date
LV11884A true LV11884A (lv) 1997-12-20
LV11884B LV11884B (lv) 1998-03-20

Family

ID=6532126

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-97-94A LV11884B (lv) 1994-11-03 1997-05-14 Ciklosporīna orālās ārstnieciskās formas ar augstu biopieejamību

Country Status (27)

Country Link
US (1) US6486124B2 (lv)
EP (1) EP0789580B1 (lv)
JP (1) JP3833248B2 (lv)
KR (1) KR970704464A (lv)
CN (1) CN1121238C (lv)
AT (1) ATE218359T1 (lv)
AU (1) AU715165B2 (lv)
BG (1) BG62955B1 (lv)
BR (1) BR9509550A (lv)
CA (1) CA2231404C (lv)
CZ (1) CZ287806B6 (lv)
DE (2) DE59510233D1 (lv)
DK (1) DK0789580T3 (lv)
EE (1) EE03425B1 (lv)
ES (1) ES2177652T3 (lv)
FI (1) FI118722B (lv)
HU (1) HUT77283A (lv)
LT (1) LT4306B (lv)
LV (1) LV11884B (lv)
NO (1) NO970741D0 (lv)
PL (1) PL183579B1 (lv)
PT (1) PT789580E (lv)
RU (1) RU2158601C2 (lv)
SK (1) SK164796A3 (lv)
TR (1) TR199501361A2 (lv)
TW (1) TW492876B (lv)
WO (1) WO1996014079A1 (lv)

Families Citing this family (31)

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PT789580E (pt) 1994-11-03 2002-09-30 Novartis Ag Formulacoes de ciclosporina para administracao oral com composicao simples e alta biodisponibilidade e processo para a sua producao
US5834017A (en) * 1995-08-25 1998-11-10 Sangstat Medical Corporation Oral cyclopsporin formulations
US5962019A (en) * 1995-08-25 1999-10-05 Sangstat Medical Corporation Oral cyclosporin formulations
AU709548B2 (en) * 1995-08-25 1999-09-02 Sangstat Medical Corporation Oral cyclosporin formulations
US5766629A (en) * 1995-08-25 1998-06-16 Sangstat Medical Corporation Oral cyclosporin formulations
DE19549852B4 (de) * 1995-11-29 2009-06-04 Novartis Ag Cyclosporin enthaltende Präparate
CZ295207B6 (cs) * 1997-01-30 2005-06-15 Novartis Ag Tvrdá želatinová tobolka obsahující cyklosporin A
AU762247B2 (en) * 1997-01-30 2003-06-19 Novartis Ag Oil-free pharmaceutical compositions containing cyclosporin A
DE19821951A1 (de) * 1998-05-15 1999-11-18 Basf Ag Cyclosporin-Zubereitungen
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US20070015691A1 (en) * 2005-07-13 2007-01-18 Allergan, Inc. Cyclosporin compositions
US7276476B2 (en) * 2005-07-13 2007-10-02 Allergan, Inc. Cyclosporin compositions
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US20070015693A1 (en) * 2005-07-13 2007-01-18 Allergan, Inc. Cyclosporin compositions
US7501393B2 (en) * 2005-07-27 2009-03-10 Allergan, Inc. Pharmaceutical compositions comprising cyclosporins
US7745400B2 (en) * 2005-10-14 2010-06-29 Gregg Feinerman Prevention and treatment of ocular side effects with a cyclosporin
US9839667B2 (en) 2005-10-14 2017-12-12 Allergan, Inc. Prevention and treatment of ocular side effects with a cyclosporin
ES2666191T3 (es) * 2011-11-15 2018-05-03 Allergan, Inc. Un proceso para la cristalización de la forma 2 de la ciclosporina A
ES2791751T3 (es) * 2011-11-15 2020-11-05 Allergan Inc Suspensiones de forma 2 de ciclosporina A

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Also Published As

Publication number Publication date
US6486124B2 (en) 2002-11-26
DK0789580T3 (da) 2002-09-09
WO1996014079A1 (de) 1996-05-17
US20020025927A1 (en) 2002-02-28
KR970704464A (ko) 1997-09-06
DE59510233D1 (de) 2002-07-11
TR199501361A2 (tr) 1996-06-21
FI970634A (fi) 1997-02-14
CA2231404C (en) 2009-02-17
LV11884B (lv) 1998-03-20
HUT77283A (hu) 1998-03-30
SK164796A3 (en) 1997-06-04
EP0789580B1 (de) 2002-06-05
CA2231404A1 (en) 1996-05-17
BG62955B1 (bg) 2000-12-29
BR9509550A (pt) 1997-09-16
BG101117A (en) 1997-08-29
RU2158601C2 (ru) 2000-11-10
NO970741L (no) 1997-02-18
EE03425B1 (et) 2001-06-15
DE19539860A1 (de) 1996-05-09
CN1162265A (zh) 1997-10-15
CZ287806B6 (en) 2001-02-14
CZ361696A3 (en) 1997-07-16
AU2975195A (en) 1996-05-31
EP0789580A1 (de) 1997-08-20
JPH10508306A (ja) 1998-08-18
EE9700112A (et) 1997-12-15
ES2177652T3 (es) 2002-12-16
PL183579B1 (pl) 2002-06-28
CN1121238C (zh) 2003-09-17
AU715165B2 (en) 2000-01-20
TW492876B (en) 2002-07-01
LT4306B (lt) 1998-03-25
ATE218359T1 (de) 2002-06-15
PL318560A1 (en) 1997-06-23
FI970634A0 (fi) 1997-02-14
FI118722B (fi) 2008-02-29
LT97002A (en) 1997-11-25
NO970741D0 (no) 1997-02-18
PT789580E (pt) 2002-09-30
JP3833248B2 (ja) 2006-10-11

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