KR20180127416A - Rnaset2를 통한 염증성 장 질환의 진단 방법 - Google Patents

Rnaset2를 통한 염증성 장 질환의 진단 방법 Download PDF

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KR20180127416A
KR20180127416A KR1020187030036A KR20187030036A KR20180127416A KR 20180127416 A KR20180127416 A KR 20180127416A KR 1020187030036 A KR1020187030036 A KR 1020187030036A KR 20187030036 A KR20187030036 A KR 20187030036A KR 20180127416 A KR20180127416 A KR 20180127416A
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rnaset2
subject
disease
expression
tl1a
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Korean (ko)
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레베카 곤스카이
스테판 알 타간
리차드 엘 딤
필립 플레슈너
더모트 피 맥거번
자닌 빌스보러
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세다르스-신나이 메디칼 센터
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Priority to KR1020227001356A priority Critical patent/KR102464372B1/ko
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/154—Methylation markers
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/06—Gastro-intestinal diseases
    • G01N2800/065—Bowel diseases, e.g. Crohn, ulcerative colitis, IBS

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  • Chemical & Material Sciences (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
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  • General Chemical & Material Sciences (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
KR1020187030036A 2016-03-17 2017-03-17 Rnaset2를 통한 염증성 장 질환의 진단 방법 Ceased KR20180127416A (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
KR1020227001356A KR102464372B1 (ko) 2016-03-17 2017-03-17 Rnaset2를 통한 염증성 장 질환의 진단 방법

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662309817P 2016-03-17 2016-03-17
US62/309,817 2016-03-17
US201762457048P 2017-02-09 2017-02-09
US62/457,048 2017-02-09
PCT/US2017/023082 WO2017161342A1 (en) 2016-03-17 2017-03-17 Methods of diagnosing inflammatory bowel disease through rnaset2

Related Child Applications (1)

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KR1020227001356A Division KR102464372B1 (ko) 2016-03-17 2017-03-17 Rnaset2를 통한 염증성 장 질환의 진단 방법

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KR20180127416A true KR20180127416A (ko) 2018-11-28

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KR1020187030036A Ceased KR20180127416A (ko) 2016-03-17 2017-03-17 Rnaset2를 통한 염증성 장 질환의 진단 방법
KR1020247020176A Ceased KR20240095481A (ko) 2016-03-17 2017-03-17 Rnaset2를 통한 염증성 장 질환의 진단 방법
KR1020227001356A Active KR102464372B1 (ko) 2016-03-17 2017-03-17 Rnaset2를 통한 염증성 장 질환의 진단 방법
KR1020227038458A Ceased KR20220153109A (ko) 2016-03-17 2017-03-17 Rnaset2를 통한 염증성 장 질환의 진단 방법

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KR1020247020176A Ceased KR20240095481A (ko) 2016-03-17 2017-03-17 Rnaset2를 통한 염증성 장 질환의 진단 방법
KR1020227001356A Active KR102464372B1 (ko) 2016-03-17 2017-03-17 Rnaset2를 통한 염증성 장 질환의 진단 방법
KR1020227038458A Ceased KR20220153109A (ko) 2016-03-17 2017-03-17 Rnaset2를 통한 염증성 장 질환의 진단 방법

Country Status (6)

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US (2) US11186872B2 (https=)
EP (1) EP3430172A4 (https=)
JP (3) JP7082945B2 (https=)
KR (4) KR20180127416A (https=)
CN (2) CN118773299A (https=)
WO (1) WO2017161342A1 (https=)

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KR102343212B1 (ko) 2013-03-27 2021-12-23 세다르스-신나이 메디칼 센터 Tl1a 기능 및 관련된 신호전달 경로의 저해에 의한 섬유증 및 염증의 완화 및 반전
WO2014186750A2 (en) 2013-05-17 2014-11-20 Cedars-Sinai Medical Center Variants of tnfsf15 and dcr3 associated with crohn's disease
WO2015010108A1 (en) 2013-07-19 2015-01-22 Cedars-Sinai Medical Center Signature of tl1a (tnfsf15) signaling pathway
TWI703158B (zh) 2015-09-18 2020-09-01 美商希佛隆公司 特異性結合tl1a之抗體
US11186872B2 (en) 2016-03-17 2021-11-30 Cedars-Sinai Medical Center Methods of diagnosing inflammatory bowel disease through RNASET2
CA3097874A1 (en) * 2018-04-24 2019-10-31 Cedars-Sinai Medical Center Methods and systems for characterizing severe crohn's disease
CN109266749A (zh) * 2018-11-23 2019-01-25 皖南医学院 一种检测rnaset2基因启动子甲基化的引物及其检测方法
WO2020112890A1 (en) 2018-11-29 2020-06-04 Cedars-Sinai Medical Center Rnaset2 compositions and methods of treatment therewith
KR20210130168A (ko) * 2019-02-08 2021-10-29 세다르스-신나이 메디칼 센터 Il18r1을 표적화하는 염증성 질환의 치료를 위한 방법, 시스템 및 키트
AU2020228760A1 (en) 2019-02-25 2021-09-23 Glaxosmithkline Intellectual Property (No. 3) Limited Treatment with P2X3 modulators
CN113710316A (zh) * 2019-03-26 2021-11-26 阿斯特捷利康合作创业有限责任公司 适合于il23拮抗剂疗法的患者群体
JP2022533956A (ja) 2019-05-14 2022-07-27 プロメテウス バイオサイエンシーズ，インク． Ｔｌ１ａ患者を選択する方法、システム、およびデバイス
EP3748017A1 (en) * 2019-06-07 2020-12-09 Academisch Medisch Centrum Methylation markers for predicting sensitivity to treatment with antibody based therapy
EP4162067A4 (en) * 2020-06-03 2024-07-10 Cedars-Sinai Medical Center METHODS AND SYSTEMS FOR MEASURING THE RECURRENCE OF POSTOPERATIVE DISEASES
EP4263585A4 (en) * 2020-12-21 2024-11-27 Cedars-Sinai Medical Center THERAPEUTIC COMPOSITIONS OF TL1A AND METHODS OF TREATMENT USING THEM
CN113436741B (zh) * 2021-07-16 2023-02-28 四川大学华西医院 基于组织特异增强子区域dna甲基化的肺癌复发预测方法
JPWO2023243470A1 (https=) 2022-06-14 2023-12-21
WO2024233362A1 (en) * 2023-05-05 2024-11-14 Cedars-Sinai Medical Center Compositions and methods for treating inflammatory bowel disease (ibd)
CN121843714A (zh) 2023-08-11 2026-04-10 派拉冈医疗公司 Tl1a结合抗体及使用方法

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