KR100679872B1 - 사이클로포스파미드 제피 정제 및 이의 제조방법 - Google Patents

사이클로포스파미드 제피 정제 및 이의 제조방법 Download PDF

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Publication number
KR100679872B1
KR100679872B1 KR1020007014142A KR20007014142A KR100679872B1 KR 100679872 B1 KR100679872 B1 KR 100679872B1 KR 1020007014142 A KR1020007014142 A KR 1020007014142A KR 20007014142 A KR20007014142 A KR 20007014142A KR 100679872 B1 KR100679872 B1 KR 100679872B1
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KR
South Korea
Prior art keywords
weight
parts
cyclophosphamide
tablet
talc
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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KR1020007014142A
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English (en)
Korean (ko)
Other versions
KR20010052819A (ko
Inventor
엔겔위르겐
라베르트위르겐
자우어비어디터
비헤르트부르크하르트
Original Assignee
아스타 메디카 아크티엔게젤샤프트
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Publication of KR20010052819A publication Critical patent/KR20010052819A/ko
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Publication of KR100679872B1 publication Critical patent/KR100679872B1/ko
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020007014142A 1998-06-15 1999-06-08 사이클로포스파미드 제피 정제 및 이의 제조방법 Expired - Fee Related KR100679872B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19826517.4 1998-06-15
DE19826517A DE19826517B4 (de) 1998-06-15 1998-06-15 Verfahren zur Herstellung von Filmtabletten mit Cyclophosphamid als Wirkstoff und daraus hergestellte Cyclophosphamid-Filmtablette

Publications (2)

Publication Number Publication Date
KR20010052819A KR20010052819A (ko) 2001-06-25
KR100679872B1 true KR100679872B1 (ko) 2007-02-07

Family

ID=7870877

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020007014142A Expired - Fee Related KR100679872B1 (ko) 1998-06-15 1999-06-08 사이클로포스파미드 제피 정제 및 이의 제조방법

Country Status (28)

Country Link
US (1) US20010046504A1 (enExample)
EP (1) EP1089739B1 (enExample)
JP (1) JP4891478B2 (enExample)
KR (1) KR100679872B1 (enExample)
CN (1) CN1177590C (enExample)
AR (1) AR019670A1 (enExample)
AT (1) ATE310523T1 (enExample)
AU (1) AU771284B2 (enExample)
BG (1) BG65253B1 (enExample)
BR (1) BR9911276A (enExample)
CA (1) CA2333682C (enExample)
CO (1) CO5070588A1 (enExample)
CZ (1) CZ302157B6 (enExample)
DE (3) DE19826517B4 (enExample)
DK (1) DK1089739T3 (enExample)
ES (1) ES2255276T3 (enExample)
HU (1) HU226528B1 (enExample)
IL (2) IL139944A0 (enExample)
NO (1) NO325154B1 (enExample)
NZ (1) NZ508888A (enExample)
PL (1) PL193398B1 (enExample)
RU (1) RU2236231C2 (enExample)
SK (1) SK286185B6 (enExample)
TR (1) TR200003702T2 (enExample)
TW (1) TWI242450B (enExample)
UA (1) UA75566C2 (enExample)
WO (1) WO1999065499A1 (enExample)
ZA (1) ZA200006998B (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT500063A1 (de) 1999-11-23 2005-10-15 Sandoz Ag Beschichtete tablettenkerne
ES2377729T3 (es) 2002-02-21 2012-03-30 Valeant International (Barbados) Srl Formulaciones de liberación modificada de al menos una forma de tramadol
DE102005008797A1 (de) * 2005-02-25 2006-09-07 Baxter International Inc., Deerfield Trofosfamid-haltige Filmtabletten und Verfahren zu deren Herstellung
US9452980B2 (en) 2009-12-22 2016-09-27 Hoffmann-La Roche Inc. Substituted benzamides
JO3659B1 (ar) * 2010-06-02 2020-08-27 Astellas Deutschland Gmbh أشكال جرعات بينداموستين عن طريق الفم وإستخداماته العلاجية
UA112170C2 (uk) 2010-12-10 2016-08-10 Санофі Протипухлинна комбінація, що містить антитіло, яке специфічно розпізнає cd38, і бортезоміб
EP2745833A1 (en) * 2012-12-21 2014-06-25 Institut Gustave Roussy Soluble, dispersible or orodispersible tablets comprising cyclophosphamide
US10016447B2 (en) 2014-09-26 2018-07-10 Intas Pharmaceuticals Ltd. Pharmaceutical composition having improved content uniformity
HRP20201405T1 (hr) 2016-03-17 2020-11-27 F. Hoffmann - La Roche Ag Derivat 5-etil-4-metil-pirazol-3-karboksamida, koji djeluje kao agonist taar-a

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5047246A (en) * 1988-09-09 1991-09-10 Bristol-Myers Company Direct compression cyclophosphamide tablet
US5110814A (en) * 1989-01-11 1992-05-05 Asta Pharma Ag Azelastine and its salts used to combat psoriasis
UA26305A (uk) * 1990-07-16 1999-08-30 Аста Медіка Аг Таблетка, спосіб її одержаhhя, граhулят та спосіб одержаhhя граhулята
DE59101431D1 (de) * 1990-07-16 1994-05-26 Asta Medica Ag Tablette und Granulat welche als Wirkstoff Mesna enthalten.
RO113611B1 (ro) * 1990-08-03 1998-09-30 Asta Pharma Ag Preparate solide de ifosfamida, administrate oral si procedeu de obtinere
GB9115160D0 (en) * 1991-07-12 1991-08-28 Erba Carlo Spa Methylen-oxindole derivatives and process for their preparation
GB9119983D0 (en) * 1991-09-19 1991-11-06 Erba Carlo Spa Dihydropyridine derivatives useful in antitumor therapy
DE4433764A1 (de) * 1994-09-22 1996-03-28 Asta Medica Ag Darreichungsformen enthaltend alpha-Liponsäure, feste Salze von R-Thioctsäure mit verbesserter Freisetzung und Bioverfügbarkeit
JP3049095B2 (ja) * 1996-02-22 2000-06-05 サムジン ファーマシューチカル カンパニー，リミテッド 新規抗ウイルス性置換ピリミジンジオン単素炭素環式ヌクレオシド誘導体及びその製造方法とこれを活性成分として含有する組成物
JPH11322596A (ja) * 1998-05-12 1999-11-24 Shionogi & Co Ltd 白金錯体および環状リン酸エステルアミドを含有する抗癌剤
US20040034099A1 (en) * 2002-06-27 2004-02-19 Ramsey Beverly J. Pharmaceutical composition

Also Published As

Publication number Publication date
ZA200006998B (en) 2001-11-20
AR019670A1 (es) 2002-03-13
DK1089739T3 (da) 2006-04-03
SK18582000A3 (sk) 2001-08-06
CN1177590C (zh) 2004-12-01
DE59912829D1 (de) 2005-12-29
BG65253B1 (bg) 2007-10-31
NO20006325D0 (no) 2000-12-12
DE29921466U1 (de) 2000-03-09
JP2002518334A (ja) 2002-06-25
TR200003702T2 (tr) 2001-06-21
DE19826517A1 (de) 2000-03-02
CN1305381A (zh) 2001-07-25
PL193398B1 (pl) 2007-02-28
CO5070588A1 (es) 2001-08-28
ES2255276T3 (es) 2006-06-16
NO20006325L (no) 2000-12-12
RU2236231C2 (ru) 2004-09-20
KR20010052819A (ko) 2001-06-25
BR9911276A (pt) 2001-10-23
EP1089739B1 (de) 2005-11-23
CA2333682A1 (en) 1999-12-23
US20010046504A1 (en) 2001-11-29
AU771284B2 (en) 2004-03-18
WO1999065499A1 (de) 1999-12-23
JP4891478B2 (ja) 2012-03-07
UA75566C2 (en) 2006-05-15
HUP0102788A2 (hu) 2002-03-28
CA2333682C (en) 2008-01-29
IL139944A0 (en) 2002-02-10
PL344832A1 (en) 2001-11-19
NO325154B1 (no) 2008-02-11
DE19826517B4 (de) 2006-03-23
IL139944A (en) 2006-08-01
HK1037959A1 (en) 2002-03-01
NZ508888A (en) 2003-11-28
EP1089739A1 (de) 2001-04-11
AU4508599A (en) 2000-01-05
HU226528B1 (en) 2009-03-30
BG105139A (en) 2001-07-31
CZ302157B6 (cs) 2010-11-18
TWI242450B (en) 2005-11-01
ATE310523T1 (de) 2005-12-15
CZ20004489A3 (cs) 2001-08-15
SK286185B6 (sk) 2008-05-06
HUP0102788A3 (en) 2002-12-28

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