TR200003702T2 - Siklofosfamid filmi kaplanmış tabletler - Google Patents

Siklofosfamid filmi kaplanmış tabletler

Info

Publication number
TR200003702T2
TR200003702T2 TR2000/03702T TR200003702T TR200003702T2 TR 200003702 T2 TR200003702 T2 TR 200003702T2 TR 2000/03702 T TR2000/03702 T TR 2000/03702T TR 200003702 T TR200003702 T TR 200003702T TR 200003702 T2 TR200003702 T2 TR 200003702T2
Authority
TR
Turkey
Prior art keywords
cyclophosphamide
coated tablets
lubricants
fillers
core
Prior art date
Application number
TR2000/03702T
Other languages
English (en)
Inventor
Engel Jurgen
Rawert Jurgen
Sauerbier Dieter
Wichert Burkhard
Original Assignee
Asta Medica Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica Aktiengesellschaft filed Critical Asta Medica Aktiengesellschaft
Publication of TR200003702T2 publication Critical patent/TR200003702T2/tr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Bulus, aktif madde olarak siklofosfamide sahip olan kaplanmis tabletlere iliskindir, bu tabletler, çekirdekte, siklofosfamid, bir ya da daha çok dolgu maddesi, bir ya da bir kaç kuru baglama maddesini ihtiva etmekte, fakat, önceden sisirilmis nisastalar, akis düzenleme maddeleri ve kayganlastirma maddelerini ihtiva etmemektedir. Bulusun tercih edilen bir düzenlemesinde, film tabletinin çekirdegi, laktoz monohidrat, D-manit ya da CaHPO4'ü dolgu maddeleri olarak, önceden sisirilmemis misir nisastasi ve mikro ince selülozu kuru baglayici madde olarak, yüksek ölçüde dagitilmis silikon oksiti akis düzenleme maddeleri olarak ve magnezyum stearat, stearik asit, giliserin palmitostearat, polietilen glikol, talk ya da gliserin monobehenati kayganlastirma maddeleri olarak ihtiva etmektedir.
TR2000/03702T 1998-06-15 1999-06-08 Siklofosfamid filmi kaplanmış tabletler TR200003702T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19826517A DE19826517B4 (de) 1998-06-15 1998-06-15 Verfahren zur Herstellung von Filmtabletten mit Cyclophosphamid als Wirkstoff und daraus hergestellte Cyclophosphamid-Filmtablette

Publications (1)

Publication Number Publication Date
TR200003702T2 true TR200003702T2 (tr) 2001-06-21

Family

ID=7870877

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2000/03702T TR200003702T2 (tr) 1998-06-15 1999-06-08 Siklofosfamid filmi kaplanmış tabletler

Country Status (29)

Country Link
US (1) US20010046504A1 (tr)
EP (1) EP1089739B1 (tr)
JP (1) JP4891478B2 (tr)
KR (1) KR100679872B1 (tr)
CN (1) CN1177590C (tr)
AR (1) AR019670A1 (tr)
AT (1) ATE310523T1 (tr)
AU (1) AU771284B2 (tr)
BG (1) BG65253B1 (tr)
BR (1) BR9911276A (tr)
CA (1) CA2333682C (tr)
CO (1) CO5070588A1 (tr)
CZ (1) CZ302157B6 (tr)
DE (3) DE19826517B4 (tr)
DK (1) DK1089739T3 (tr)
ES (1) ES2255276T3 (tr)
HK (1) HK1037959A1 (tr)
HU (1) HU226528B1 (tr)
IL (2) IL139944A0 (tr)
NO (1) NO325154B1 (tr)
NZ (1) NZ508888A (tr)
PL (1) PL193398B1 (tr)
RU (1) RU2236231C2 (tr)
SK (1) SK286185B6 (tr)
TR (1) TR200003702T2 (tr)
TW (1) TWI242450B (tr)
UA (1) UA75566C2 (tr)
WO (1) WO1999065499A1 (tr)
ZA (1) ZA200006998B (tr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT500063A1 (de) 1999-11-23 2005-10-15 Sandoz Ag Beschichtete tablettenkerne
AU2003211146B2 (en) 2002-02-21 2007-07-19 Valeant International (Barbados) Srl Controlled release dosage forms
DE102005008797A1 (de) * 2005-02-25 2006-09-07 Baxter International Inc., Deerfield Trofosfamid-haltige Filmtabletten und Verfahren zu deren Herstellung
US9452980B2 (en) 2009-12-22 2016-09-27 Hoffmann-La Roche Inc. Substituted benzamides
JO3659B1 (ar) * 2010-06-02 2020-08-27 Astellas Deutschland Gmbh أشكال جرعات بينداموستين عن طريق الفم وإستخداماته العلاجية
UA112170C2 (uk) 2010-12-10 2016-08-10 Санофі Протипухлинна комбінація, що містить антитіло, яке специфічно розпізнає cd38, і бортезоміб
EP2745833A1 (en) * 2012-12-21 2014-06-25 Institut Gustave Roussy Soluble, dispersible or orodispersible tablets comprising cyclophosphamide
EP3197438A4 (en) 2014-09-26 2018-06-20 Intas Pharmaceuticals Ltd. Pharmaceutical composition having improved content uniformity
JP6814814B2 (ja) 2016-03-17 2021-01-20 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ Ｔａａｒのアゴニストとしての活性を有する５−エチル−４−メチル−ピラゾール−３−カルボキサミド誘導体

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5047246A (en) * 1988-09-09 1991-09-10 Bristol-Myers Company Direct compression cyclophosphamide tablet
US5110814A (en) * 1989-01-11 1992-05-05 Asta Pharma Ag Azelastine and its salts used to combat psoriasis
DE4122167A1 (de) * 1990-07-16 1992-01-23 Asta Pharma Ag Tablette und granulat enthaltend als wirkstoff mesna
UA26305A (uk) * 1990-07-16 1999-08-30 Аста Медіка Аг Таблетка, спосіб її одержаhhя, граhулят та спосіб одержаhhя граhулята
RO113611B1 (ro) * 1990-08-03 1998-09-30 Asta Pharma Ag Preparate solide de ifosfamida, administrate oral si procedeu de obtinere
DE4433764A1 (de) * 1994-09-22 1996-03-28 Asta Medica Ag Darreichungsformen enthaltend alpha-Liponsäure, feste Salze von R-Thioctsäure mit verbesserter Freisetzung und Bioverfügbarkeit
JP3049095B2 (ja) * 1996-02-22 2000-06-05 サムジン ファーマシューチカル カンパニー，リミテッド 新規抗ウイルス性置換ピリミジンジオン単素炭素環式ヌクレオシド誘導体及びその製造方法とこれを活性成分として含有する組成物
JPH11322596A (ja) * 1998-05-12 1999-11-24 Shionogi & Co Ltd 白金錯体および環状リン酸エステルアミドを含有する抗癌剤
US20040034099A1 (en) * 2002-06-27 2004-02-19 Ramsey Beverly J. Pharmaceutical composition

Also Published As

Publication number Publication date
NZ508888A (en) 2003-11-28
JP2002518334A (ja) 2002-06-25
CA2333682C (en) 2008-01-29
DE29921466U1 (de) 2000-03-09
DE59912829D1 (de) 2005-12-29
CN1177590C (zh) 2004-12-01
HUP0102788A3 (en) 2002-12-28
SK286185B6 (sk) 2008-05-06
DK1089739T3 (da) 2006-04-03
NO20006325D0 (no) 2000-12-12
CN1305381A (zh) 2001-07-25
JP4891478B2 (ja) 2012-03-07
RU2236231C2 (ru) 2004-09-20
CO5070588A1 (es) 2001-08-28
US20010046504A1 (en) 2001-11-29
PL193398B1 (pl) 2007-02-28
DE19826517B4 (de) 2006-03-23
AR019670A1 (es) 2002-03-13
AU4508599A (en) 2000-01-05
CA2333682A1 (en) 1999-12-23
HK1037959A1 (en) 2002-03-01
AU771284B2 (en) 2004-03-18
TWI242450B (en) 2005-11-01
ES2255276T3 (es) 2006-06-16
IL139944A0 (en) 2002-02-10
NO325154B1 (no) 2008-02-11
WO1999065499A1 (de) 1999-12-23
ZA200006998B (en) 2001-11-20
EP1089739B1 (de) 2005-11-23
BG65253B1 (bg) 2007-10-31
SK18582000A3 (sk) 2001-08-06
CZ302157B6 (cs) 2010-11-18
BR9911276A (pt) 2001-10-23
NO20006325L (no) 2000-12-12
KR100679872B1 (ko) 2007-02-07
ATE310523T1 (de) 2005-12-15
BG105139A (en) 2001-07-31
KR20010052819A (ko) 2001-06-25
HU226528B1 (en) 2009-03-30
DE19826517A1 (de) 2000-03-02
PL344832A1 (en) 2001-11-19
HUP0102788A2 (hu) 2002-03-28
EP1089739A1 (de) 2001-04-11
CZ20004489A3 (cs) 2001-08-15
UA75566C2 (en) 2006-05-15
IL139944A (en) 2006-08-01

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