BR9911276A - Comprimidos com pelìcula de ciclofosfamida - Google Patents

Comprimidos com pelìcula de ciclofosfamida

Info

Publication number
BR9911276A
BR9911276A BR9911276-0A BR9911276A BR9911276A BR 9911276 A BR9911276 A BR 9911276A BR 9911276 A BR9911276 A BR 9911276A BR 9911276 A BR9911276 A BR 9911276A
Authority
BR
Brazil
Prior art keywords
cyclophosphamide
tablets
flow regulating
wrapping
glycerin
Prior art date
Application number
BR9911276-0A
Other languages
English (en)
Inventor
Juergen Engel
Juergen Rawert
Dieter Sauerbier
Burkhard Wichert
Original Assignee
Asta Medica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica Ag filed Critical Asta Medica Ag
Publication of BR9911276A publication Critical patent/BR9911276A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Patente de Invenção: "COMPRIMIDOS COM PELìCULA DE CICLOFOSFAMIDA". A invenção refere-se a comprimidos com invólucro com ciclofosfamida como substância ativa, que no núcleo contém ciciofosfamida, uma ou várias substâncias de enchimento, um ou mais agentes de adesão secos, no entanto, nenhum amido pré-intumescido, agentes de regulagem de escoamento e lubrificantes. De acordo com uma forma de execução da invenção o núcleo do comprimido de invólucro contém como substância de enchimento monohidrato de lactose, D-manitol ou CaHPO~ 4~, amido de milho não pré-intumescido ou celulose microfina como agente de adesão seco, como agente de regulagem de escoamento dióxido de silício altamente disperso e como lubrificante estearato de magnésio, ácido esteárico, glicerinopalmito-estearato, polietilenoglicol, talco ou monobehenato de glicerina.
BR9911276-0A 1998-06-15 1999-06-08 Comprimidos com pelìcula de ciclofosfamida BR9911276A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19826517A DE19826517B4 (de) 1998-06-15 1998-06-15 Verfahren zur Herstellung von Filmtabletten mit Cyclophosphamid als Wirkstoff und daraus hergestellte Cyclophosphamid-Filmtablette
PCT/EP1999/003920 WO1999065499A1 (de) 1998-06-15 1999-06-08 Cyclophosphamid filmtabletten

Publications (1)

Publication Number Publication Date
BR9911276A true BR9911276A (pt) 2001-10-23

Family

ID=7870877

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9911276-0A BR9911276A (pt) 1998-06-15 1999-06-08 Comprimidos com pelìcula de ciclofosfamida

Country Status (29)

Country Link
US (1) US20010046504A1 (pt)
EP (1) EP1089739B1 (pt)
JP (1) JP4891478B2 (pt)
KR (1) KR100679872B1 (pt)
CN (1) CN1177590C (pt)
AR (1) AR019670A1 (pt)
AT (1) ATE310523T1 (pt)
AU (1) AU771284B2 (pt)
BG (1) BG65253B1 (pt)
BR (1) BR9911276A (pt)
CA (1) CA2333682C (pt)
CO (1) CO5070588A1 (pt)
CZ (1) CZ302157B6 (pt)
DE (3) DE19826517B4 (pt)
DK (1) DK1089739T3 (pt)
ES (1) ES2255276T3 (pt)
HK (1) HK1037959A1 (pt)
HU (1) HU226528B1 (pt)
IL (2) IL139944A0 (pt)
NO (1) NO325154B1 (pt)
NZ (1) NZ508888A (pt)
PL (1) PL193398B1 (pt)
RU (1) RU2236231C2 (pt)
SK (1) SK286185B6 (pt)
TR (1) TR200003702T2 (pt)
TW (1) TWI242450B (pt)
UA (1) UA75566C2 (pt)
WO (1) WO1999065499A1 (pt)
ZA (1) ZA200006998B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT500063A1 (de) 1999-11-23 2005-10-15 Sandoz Ag Beschichtete tablettenkerne
ATE536173T1 (de) 2002-02-21 2011-12-15 Biovail Lab Int Srl Formulierungen mit modifizierter freisetzung von mindestens einer form von tramadol
DE102005008797A1 (de) * 2005-02-25 2006-09-07 Baxter International Inc., Deerfield Trofosfamid-haltige Filmtabletten und Verfahren zu deren Herstellung
US9452980B2 (en) 2009-12-22 2016-09-27 Hoffmann-La Roche Inc. Substituted benzamides
JO3659B1 (ar) * 2010-06-02 2020-08-27 Astellas Deutschland Gmbh أشكال جرعات بينداموستين عن طريق الفم وإستخداماته العلاجية
UA112170C2 (uk) 2010-12-10 2016-08-10 Санофі Протипухлинна комбінація, що містить антитіло, яке специфічно розпізнає cd38, і бортезоміб
EP2745833A1 (en) * 2012-12-21 2014-06-25 Institut Gustave Roussy Soluble, dispersible or orodispersible tablets comprising cyclophosphamide
EP3197438A4 (en) 2014-09-26 2018-06-20 Intas Pharmaceuticals Ltd. Pharmaceutical composition having improved content uniformity
MY195528A (en) 2016-03-17 2023-01-30 Hoffmann La Roche 5-Ethyl-4-Methyl-Pyrazole-3-Carboxamide Derivative Having Activity as Agonist of Taar

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5047246A (en) * 1988-09-09 1991-09-10 Bristol-Myers Company Direct compression cyclophosphamide tablet
US5110814A (en) * 1989-01-11 1992-05-05 Asta Pharma Ag Azelastine and its salts used to combat psoriasis
UA26305A (uk) * 1990-07-16 1999-08-30 Аста Медіка Аг Таблетка, спосіб її одержаhhя, граhулят та спосіб одержаhhя граhулята
DE59101431D1 (de) * 1990-07-16 1994-05-26 Asta Medica Ag Tablette und Granulat welche als Wirkstoff Mesna enthalten.
RO113611B1 (ro) * 1990-08-03 1998-09-30 Asta Pharma Ag Preparate solide de ifosfamida, administrate oral si procedeu de obtinere
DE4433764A1 (de) * 1994-09-22 1996-03-28 Asta Medica Ag Darreichungsformen enthaltend alpha-Liponsäure, feste Salze von R-Thioctsäure mit verbesserter Freisetzung und Bioverfügbarkeit
DE69628750T2 (de) * 1996-02-22 2004-04-29 Samjin Pharm, Co., Ltd. Neue antivirale, homocarbozklische nukleosidderivate von substituierten pyrimidindionen, verfahren zu ihrer herstellung und zusammensetzungen, die diese als aktiven bestandteil enthalten
JPH11322596A (ja) * 1998-05-12 1999-11-24 Shionogi & Co Ltd 白金錯体および環状リン酸エステルアミドを含有する抗癌剤
US20040034099A1 (en) * 2002-06-27 2004-02-19 Ramsey Beverly J. Pharmaceutical composition

Also Published As

Publication number Publication date
KR100679872B1 (ko) 2007-02-07
DE59912829D1 (de) 2005-12-29
NO325154B1 (no) 2008-02-11
AR019670A1 (es) 2002-03-13
ATE310523T1 (de) 2005-12-15
HUP0102788A3 (en) 2002-12-28
DE19826517A1 (de) 2000-03-02
CA2333682C (en) 2008-01-29
DK1089739T3 (da) 2006-04-03
IL139944A0 (en) 2002-02-10
NZ508888A (en) 2003-11-28
HU226528B1 (en) 2009-03-30
EP1089739A1 (de) 2001-04-11
AU771284B2 (en) 2004-03-18
SK286185B6 (sk) 2008-05-06
TR200003702T2 (tr) 2001-06-21
TWI242450B (en) 2005-11-01
IL139944A (en) 2006-08-01
NO20006325D0 (no) 2000-12-12
US20010046504A1 (en) 2001-11-29
DE19826517B4 (de) 2006-03-23
NO20006325L (no) 2000-12-12
CZ302157B6 (cs) 2010-11-18
PL193398B1 (pl) 2007-02-28
BG65253B1 (bg) 2007-10-31
CZ20004489A3 (cs) 2001-08-15
WO1999065499A1 (de) 1999-12-23
HK1037959A1 (en) 2002-03-01
AU4508599A (en) 2000-01-05
PL344832A1 (en) 2001-11-19
CA2333682A1 (en) 1999-12-23
JP2002518334A (ja) 2002-06-25
KR20010052819A (ko) 2001-06-25
HUP0102788A2 (hu) 2002-03-28
EP1089739B1 (de) 2005-11-23
ZA200006998B (en) 2001-11-20
CO5070588A1 (es) 2001-08-28
CN1305381A (zh) 2001-07-25
UA75566C2 (en) 2006-05-15
BG105139A (en) 2001-07-31
DE29921466U1 (de) 2000-03-09
ES2255276T3 (es) 2006-06-16
SK18582000A3 (sk) 2001-08-06
RU2236231C2 (ru) 2004-09-20
CN1177590C (zh) 2004-12-01
JP4891478B2 (ja) 2012-03-07

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PRESENTE PEDIDO, UMA VEZ QUE O MESMO NAO ATENDE AOS REQUISITOS DOS ARTIGOS 8O E 13 DA LPI