HUP0102788A2 - Ciklofoszfamid filmtabletták és eljárás az előállításukra - Google Patents

Ciklofoszfamid filmtabletták és eljárás az előállításukra

Info

Publication number
HUP0102788A2
HUP0102788A2 HU0102788A HUP0102788A HUP0102788A2 HU P0102788 A2 HUP0102788 A2 HU P0102788A2 HU 0102788 A HU0102788 A HU 0102788A HU P0102788 A HUP0102788 A HU P0102788A HU P0102788 A2 HUP0102788 A2 HU P0102788A2
Authority
HU
Hungary
Prior art keywords
cyclophosphamide
coated tablets
preparation
tablet
fillers
Prior art date
Application number
HU0102788A
Other languages
English (en)
Inventor
Jürgen Engel
Jürgen Rawert
Dieter Sauerbier
Burkhard Wichert
Original Assignee
Asta Medica Ag.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica Ag. filed Critical Asta Medica Ag.
Publication of HUP0102788A2 publication Critical patent/HUP0102788A2/hu
Publication of HUP0102788A3 publication Critical patent/HUP0102788A3/hu
Publication of HU226528B1 publication Critical patent/HU226528B1/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A találmány ciklofoszfamidot tartalmazó filmtablettákra,tablettamagokra és az előállításukra alkalmas eljárásra vonatkozik. Afilmtabletta egy tablettamagból, amely ciklofoszfamid hatóanyagot, egyvagy több töltőanyagot, egy vagy több szárazon kötő anyagot, egy vagytöbb folyásszabályozó szert, egy vagy több kenőanyagot tartalmaz, ésegy alkalmas filmbevonatból áll, a tablettamag legalább a töltőanyagokegyikeként laktóz-monohidrátot foglal magában, és szárazon kötőszerként előduzzasztott keményítőt nem tartalmaz. Ó
HU0102788A 1998-06-15 1999-06-08 Cyclophosphamide coated tablets HU226528B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19826517A DE19826517B4 (de) 1998-06-15 1998-06-15 Verfahren zur Herstellung von Filmtabletten mit Cyclophosphamid als Wirkstoff und daraus hergestellte Cyclophosphamid-Filmtablette
PCT/EP1999/003920 WO1999065499A1 (de) 1998-06-15 1999-06-08 Cyclophosphamid filmtabletten

Publications (3)

Publication Number Publication Date
HUP0102788A2 true HUP0102788A2 (hu) 2002-03-28
HUP0102788A3 HUP0102788A3 (en) 2002-12-28
HU226528B1 HU226528B1 (en) 2009-03-30

Family

ID=7870877

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0102788A HU226528B1 (en) 1998-06-15 1999-06-08 Cyclophosphamide coated tablets

Country Status (29)

Country Link
US (1) US20010046504A1 (hu)
EP (1) EP1089739B1 (hu)
JP (1) JP4891478B2 (hu)
KR (1) KR100679872B1 (hu)
CN (1) CN1177590C (hu)
AR (1) AR019670A1 (hu)
AT (1) ATE310523T1 (hu)
AU (1) AU771284B2 (hu)
BG (1) BG65253B1 (hu)
BR (1) BR9911276A (hu)
CA (1) CA2333682C (hu)
CO (1) CO5070588A1 (hu)
CZ (1) CZ302157B6 (hu)
DE (3) DE19826517B4 (hu)
DK (1) DK1089739T3 (hu)
ES (1) ES2255276T3 (hu)
HK (1) HK1037959A1 (hu)
HU (1) HU226528B1 (hu)
IL (2) IL139944A0 (hu)
NO (1) NO325154B1 (hu)
NZ (1) NZ508888A (hu)
PL (1) PL193398B1 (hu)
RU (1) RU2236231C2 (hu)
SK (1) SK286185B6 (hu)
TR (1) TR200003702T2 (hu)
TW (1) TWI242450B (hu)
UA (1) UA75566C2 (hu)
WO (1) WO1999065499A1 (hu)
ZA (1) ZA200006998B (hu)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT500063A1 (de) 1999-11-23 2005-10-15 Sandoz Ag Beschichtete tablettenkerne
ATE536173T1 (de) 2002-02-21 2011-12-15 Biovail Lab Int Srl Formulierungen mit modifizierter freisetzung von mindestens einer form von tramadol
DE102005008797A1 (de) * 2005-02-25 2006-09-07 Baxter International Inc., Deerfield Trofosfamid-haltige Filmtabletten und Verfahren zu deren Herstellung
US9452980B2 (en) 2009-12-22 2016-09-27 Hoffmann-La Roche Inc. Substituted benzamides
JO3659B1 (ar) * 2010-06-02 2020-08-27 Astellas Deutschland Gmbh أشكال جرعات بينداموستين عن طريق الفم وإستخداماته العلاجية
UA112170C2 (uk) 2010-12-10 2016-08-10 Санофі Протипухлинна комбінація, що містить антитіло, яке специфічно розпізнає cd38, і бортезоміб
EP2745833A1 (en) * 2012-12-21 2014-06-25 Institut Gustave Roussy Soluble, dispersible or orodispersible tablets comprising cyclophosphamide
WO2016046797A1 (en) 2014-09-26 2016-03-31 Intas Pharmaceuticals Ltd. Pharmaceutical composition having improved content uniformity
SG11201807516UA (en) 2016-03-17 2018-09-27 Hoffmann La Roche 5-ethyl-4-methyl-pyrazole-3-carboxamide derivative having activity as agonist of taar

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5047246A (en) * 1988-09-09 1991-09-10 Bristol-Myers Company Direct compression cyclophosphamide tablet
US5110814A (en) * 1989-01-11 1992-05-05 Asta Pharma Ag Azelastine and its salts used to combat psoriasis
DK0468245T3 (da) * 1990-07-16 1994-05-16 Asta Medica Ag Tablet og granulat indeholdende mesna som aktivt middel
UA26305A (uk) * 1990-07-16 1999-08-30 Аста Медіка Аг Таблетка, спосіб її одержаhhя, граhулят та спосіб одержаhhя граhулята
RO113611B1 (ro) * 1990-08-03 1998-09-30 Asta Pharma Ag Preparate solide de ifosfamida, administrate oral si procedeu de obtinere
DE4433764A1 (de) * 1994-09-22 1996-03-28 Asta Medica Ag Darreichungsformen enthaltend alpha-Liponsäure, feste Salze von R-Thioctsäure mit verbesserter Freisetzung und Bioverfügbarkeit
AU710490B2 (en) * 1996-02-22 1999-09-23 Samjin Pharmaceutical Co., Ltd. New antiviral substituted pyrimidinedione homocarbocyclic nucleoside derivatives and methods for the preparation thereof and compositions containing the same as active ingredients
JPH11322596A (ja) * 1998-05-12 1999-11-24 Shionogi & Co Ltd 白金錯体および環状リン酸エステルアミドを含有する抗癌剤
US20040034099A1 (en) * 2002-06-27 2004-02-19 Ramsey Beverly J. Pharmaceutical composition

Also Published As

Publication number Publication date
NZ508888A (en) 2003-11-28
DE19826517B4 (de) 2006-03-23
ZA200006998B (en) 2001-11-20
DK1089739T3 (da) 2006-04-03
ATE310523T1 (de) 2005-12-15
DE59912829D1 (de) 2005-12-29
TR200003702T2 (tr) 2001-06-21
KR100679872B1 (ko) 2007-02-07
DE29921466U1 (de) 2000-03-09
CN1305381A (zh) 2001-07-25
RU2236231C2 (ru) 2004-09-20
KR20010052819A (ko) 2001-06-25
WO1999065499A1 (de) 1999-12-23
DE19826517A1 (de) 2000-03-02
NO325154B1 (no) 2008-02-11
IL139944A (en) 2006-08-01
US20010046504A1 (en) 2001-11-29
CZ20004489A3 (cs) 2001-08-15
CZ302157B6 (cs) 2010-11-18
PL193398B1 (pl) 2007-02-28
NO20006325D0 (no) 2000-12-12
EP1089739B1 (de) 2005-11-23
SK18582000A3 (sk) 2001-08-06
PL344832A1 (en) 2001-11-19
JP4891478B2 (ja) 2012-03-07
HUP0102788A3 (en) 2002-12-28
ES2255276T3 (es) 2006-06-16
AR019670A1 (es) 2002-03-13
JP2002518334A (ja) 2002-06-25
CN1177590C (zh) 2004-12-01
TWI242450B (en) 2005-11-01
BR9911276A (pt) 2001-10-23
AU4508599A (en) 2000-01-05
HK1037959A1 (en) 2002-03-01
IL139944A0 (en) 2002-02-10
CO5070588A1 (es) 2001-08-28
SK286185B6 (sk) 2008-05-06
CA2333682A1 (en) 1999-12-23
UA75566C2 (en) 2006-05-15
CA2333682C (en) 2008-01-29
HU226528B1 (en) 2009-03-30
BG65253B1 (bg) 2007-10-31
NO20006325L (no) 2000-12-12
EP1089739A1 (de) 2001-04-11
AU771284B2 (en) 2004-03-18
BG105139A (en) 2001-07-31

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Legal Events

Date Code Title Description
GB9A Succession in title

Owner name: BAXTER HEALTHCARE S. A., CH

Free format text: FORMER OWNER(S): ASTA MEDICA AG., DE

Owner name: BAXTER INTERNATIONAL INC., US

Free format text: FORMER OWNER(S): ASTA MEDICA AG., DE

MM4A Lapse of definitive patent protection due to non-payment of fees