AR019670A1 - Comprimidos de ciclofosfamida, provistos de una pelicula de recubrimiento - Google Patents

Comprimidos de ciclofosfamida, provistos de una pelicula de recubrimiento

Info

Publication number
AR019670A1
AR019670A1 ARP990102862A ARP990102862A AR019670A1 AR 019670 A1 AR019670 A1 AR 019670A1 AR P990102862 A ARP990102862 A AR P990102862A AR P990102862 A ARP990102862 A AR P990102862A AR 019670 A1 AR019670 A1 AR 019670A1
Authority
AR
Argentina
Prior art keywords
dilated
starch
film
tablets
cyclophosphamide
Prior art date
Application number
ARP990102862A
Other languages
English (en)
Original Assignee
Asta Medica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica Ag filed Critical Asta Medica Ag
Publication of AR019670A1 publication Critical patent/AR019670A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/286Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/284Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846Poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Comprimidos recubiertos con película, con ciclofosfamida como compuesto activo, que en el nucleo comprende ciclofosfamida, uno o más sustancias de relleno,uno o más ligantes secos, pero no almidon pre-dilatado, reguladores de flujo y lubricantes. Conforme a una realizacion de preferencia, el nucleo delcomprimido recubierto con película comprende como sustancia de relleno monohidrato de lactosa, D-manitol o CaHPO4, almidon no pre-dilatado o celulosa microfinacomo ligante seco, sílice altamente dispersada como regulador de flujo, y estearato de magnesio, ácido esteárico, palmitoestearato de glicerol,polietilenglicol, talco o monobehenato de glicerol como lubricante.
ARP990102862A 1998-06-15 1999-06-15 Comprimidos de ciclofosfamida, provistos de una pelicula de recubrimiento AR019670A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19826517A DE19826517B4 (de) 1998-06-15 1998-06-15 Verfahren zur Herstellung von Filmtabletten mit Cyclophosphamid als Wirkstoff und daraus hergestellte Cyclophosphamid-Filmtablette

Publications (1)

Publication Number Publication Date
AR019670A1 true AR019670A1 (es) 2002-03-13

Family

ID=7870877

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP990102862A AR019670A1 (es) 1998-06-15 1999-06-15 Comprimidos de ciclofosfamida, provistos de una pelicula de recubrimiento

Country Status (29)

Country Link
US (1) US20010046504A1 (es)
EP (1) EP1089739B1 (es)
JP (1) JP4891478B2 (es)
KR (1) KR100679872B1 (es)
CN (1) CN1177590C (es)
AR (1) AR019670A1 (es)
AT (1) ATE310523T1 (es)
AU (1) AU771284B2 (es)
BG (1) BG65253B1 (es)
BR (1) BR9911276A (es)
CA (1) CA2333682C (es)
CO (1) CO5070588A1 (es)
CZ (1) CZ302157B6 (es)
DE (3) DE19826517B4 (es)
DK (1) DK1089739T3 (es)
ES (1) ES2255276T3 (es)
HK (1) HK1037959A1 (es)
HU (1) HU226528B1 (es)
IL (2) IL139944A0 (es)
NO (1) NO325154B1 (es)
NZ (1) NZ508888A (es)
PL (1) PL193398B1 (es)
RU (1) RU2236231C2 (es)
SK (1) SK286185B6 (es)
TR (1) TR200003702T2 (es)
TW (1) TWI242450B (es)
UA (1) UA75566C2 (es)
WO (1) WO1999065499A1 (es)
ZA (1) ZA200006998B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT500063A1 (de) 1999-11-23 2005-10-15 Sandoz Ag Beschichtete tablettenkerne
ES2377729T3 (es) 2002-02-21 2012-03-30 Valeant International (Barbados) Srl Formulaciones de liberación modificada de al menos una forma de tramadol
DE102005008797A1 (de) * 2005-02-25 2006-09-07 Baxter International Inc., Deerfield Trofosfamid-haltige Filmtabletten und Verfahren zu deren Herstellung
US9452980B2 (en) 2009-12-22 2016-09-27 Hoffmann-La Roche Inc. Substituted benzamides
JO3659B1 (ar) * 2010-06-02 2020-08-27 Astellas Deutschland Gmbh أشكال جرعات بينداموستين عن طريق الفم وإستخداماته العلاجية
UA112170C2 (uk) 2010-12-10 2016-08-10 Санофі Протипухлинна комбінація, що містить антитіло, яке специфічно розпізнає cd38, і бортезоміб
EP2745833A1 (en) * 2012-12-21 2014-06-25 Institut Gustave Roussy Soluble, dispersible or orodispersible tablets comprising cyclophosphamide
EP3197438A4 (en) 2014-09-26 2018-06-20 Intas Pharmaceuticals Ltd. Pharmaceutical composition having improved content uniformity
PL3430010T3 (pl) 2016-03-17 2020-11-16 F. Hoffmann-La Roche Ag Pochodna 5-etylo-4-metylopirazolo-3-karboksyamidu wykazująca aktywność jako agonista taar

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5047246A (en) * 1988-09-09 1991-09-10 Bristol-Myers Company Direct compression cyclophosphamide tablet
US5110814A (en) * 1989-01-11 1992-05-05 Asta Pharma Ag Azelastine and its salts used to combat psoriasis
UA26305A (uk) * 1990-07-16 1999-08-30 Аста Медіка Аг Таблетка, спосіб її одержаhhя, граhулят та спосіб одержаhhя граhулята
EP0468245B1 (de) * 1990-07-16 1994-04-20 ASTA Medica Aktiengesellschaft Tablette und Granulat welche als Wirkstoff Mesna enthalten
RO113611B1 (ro) * 1990-08-03 1998-09-30 Asta Pharma Ag Preparate solide de ifosfamida, administrate oral si procedeu de obtinere
DE4433764A1 (de) * 1994-09-22 1996-03-28 Asta Medica Ag Darreichungsformen enthaltend alpha-Liponsäure, feste Salze von R-Thioctsäure mit verbesserter Freisetzung und Bioverfügbarkeit
BRPI9604907B8 (pt) * 1996-02-22 2016-11-08 Samjin Pharm Co Ltd derivados de nucleosidios homocarbociclico de pirimidinodiona substituída antiviral e composição contendo derivados de nucleosidios homocarbociclico de pirimidinodiona substituída antiviral com princípios ativos.
JPH11322596A (ja) * 1998-05-12 1999-11-24 Shionogi & Co Ltd 白金錯体および環状リン酸エステルアミドを含有する抗癌剤
US20040034099A1 (en) * 2002-06-27 2004-02-19 Ramsey Beverly J. Pharmaceutical composition

Also Published As

Publication number Publication date
AU771284B2 (en) 2004-03-18
NO20006325D0 (no) 2000-12-12
SK286185B6 (sk) 2008-05-06
HUP0102788A3 (en) 2002-12-28
DE29921466U1 (de) 2000-03-09
WO1999065499A1 (de) 1999-12-23
ATE310523T1 (de) 2005-12-15
CA2333682A1 (en) 1999-12-23
UA75566C2 (en) 2006-05-15
CA2333682C (en) 2008-01-29
BR9911276A (pt) 2001-10-23
TR200003702T2 (tr) 2001-06-21
EP1089739B1 (de) 2005-11-23
AU4508599A (en) 2000-01-05
PL193398B1 (pl) 2007-02-28
NZ508888A (en) 2003-11-28
NO325154B1 (no) 2008-02-11
CO5070588A1 (es) 2001-08-28
DK1089739T3 (da) 2006-04-03
RU2236231C2 (ru) 2004-09-20
TWI242450B (en) 2005-11-01
DE19826517B4 (de) 2006-03-23
IL139944A (en) 2006-08-01
NO20006325L (no) 2000-12-12
CN1305381A (zh) 2001-07-25
KR100679872B1 (ko) 2007-02-07
PL344832A1 (en) 2001-11-19
IL139944A0 (en) 2002-02-10
DE19826517A1 (de) 2000-03-02
CN1177590C (zh) 2004-12-01
BG105139A (en) 2001-07-31
CZ20004489A3 (cs) 2001-08-15
HUP0102788A2 (hu) 2002-03-28
DE59912829D1 (de) 2005-12-29
SK18582000A3 (sk) 2001-08-06
JP2002518334A (ja) 2002-06-25
ES2255276T3 (es) 2006-06-16
KR20010052819A (ko) 2001-06-25
CZ302157B6 (cs) 2010-11-18
HU226528B1 (en) 2009-03-30
ZA200006998B (en) 2001-11-20
JP4891478B2 (ja) 2012-03-07
EP1089739A1 (de) 2001-04-11
BG65253B1 (bg) 2007-10-31
HK1037959A1 (en) 2002-03-01
US20010046504A1 (en) 2001-11-29

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