JP6317372B2 - 試料固定及び安定化 - Google Patents

試料固定及び安定化 Download PDF

Info

Publication number
JP6317372B2
JP6317372B2 JP2015559516A JP2015559516A JP6317372B2 JP 6317372 B2 JP6317372 B2 JP 6317372B2 JP 2015559516 A JP2015559516 A JP 2015559516A JP 2015559516 A JP2015559516 A JP 2015559516A JP 6317372 B2 JP6317372 B2 JP 6317372B2
Authority
JP
Japan
Prior art keywords
rna
component
use according
mol
des
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2015559516A
Other languages
English (en)
Japanese (ja)
Other versions
JP2016510976A5 (enExample
JP2016510976A (ja
Inventor
サイモン ゴールズボロウ，アンドリュー
サイモン ゴールズボロウ，アンドリュー
ロバート ベイツ，マルコム
ロバート ベイツ，マルコム
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of JP2016510976A publication Critical patent/JP2016510976A/ja
Publication of JP2016510976A5 publication Critical patent/JP2016510976A5/ja
Application granted granted Critical
Publication of JP6317372B2 publication Critical patent/JP6317372B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/128—Chemically defined matrices for immobilising, holding or storing living parts, e.g. alginate gels; Chemically altering living parts, e.g. by cross-linking
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2250/00—Food ingredients
    • A23V2250/30—Other Organic compounds
    • A23V2250/302—Betaine, trimethylglycine
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N2001/305—Fixative compositions
    • G01N2001/307—Fixative compositions non-toxic, no Hg, no formaldehyde

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Dispersion Chemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
JP2015559516A 2013-03-01 2014-02-28 試料固定及び安定化 Active JP6317372B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1303666.0A GB201303666D0 (en) 2013-03-01 2013-03-01 Sample fixation and stabilisation
GB1303666.0 2013-03-01
PCT/EP2014/054009 WO2014131906A1 (en) 2013-03-01 2014-02-28 Sample fixation and stabilisation

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2018064225A Division JP6527616B2 (ja) 2013-03-01 2018-03-29 試料固定及び安定化

Publications (3)

Publication Number Publication Date
JP2016510976A JP2016510976A (ja) 2016-04-14
JP2016510976A5 JP2016510976A5 (enExample) 2017-04-06
JP6317372B2 true JP6317372B2 (ja) 2018-04-25

Family

ID=48142243

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2015559516A Active JP6317372B2 (ja) 2013-03-01 2014-02-28 試料固定及び安定化
JP2018064225A Active JP6527616B2 (ja) 2013-03-01 2018-03-29 試料固定及び安定化
JP2019089830A Pending JP2019141098A (ja) 2013-03-01 2019-05-10 試料固定及び安定化

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2018064225A Active JP6527616B2 (ja) 2013-03-01 2018-03-29 試料固定及び安定化
JP2019089830A Pending JP2019141098A (ja) 2013-03-01 2019-05-10 試料固定及び安定化

Country Status (9)

Country Link
US (5) US9696247B2 (enExample)
EP (3) EP3430903B1 (enExample)
JP (3) JP6317372B2 (enExample)
CN (1) CN105392363B (enExample)
AU (1) AU2014222618B2 (enExample)
CA (1) CA2904765C (enExample)
ES (1) ES2709064T3 (enExample)
GB (1) GB201303666D0 (enExample)
WO (1) WO2014131906A1 (enExample)

Families Citing this family (116)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009147537A2 (en) 2008-05-27 2009-12-10 Dako Denmark A/S Compositions and methods for detection of chromosomal aberrations with novel hybridization buffers
ES2574956T3 (es) 2011-09-26 2016-06-23 Preanalytix Gmbh Estabilización y aislamiento de ácidos nucleicos extracelulares
US11021733B2 (en) 2011-09-26 2021-06-01 Qiagen Gmbh Stabilization and isolation of extracellular nucleic acids
AU2012314514B2 (en) 2011-09-26 2018-03-15 Qiagen Gmbh Stabilisation and isolation of extracellular nucleic acids
CA2884915C (en) 2012-09-25 2022-05-17 Qiagen Gmbh Stabilisation of biological samples
GB201303666D0 (en) * 2013-03-01 2013-04-17 Goldsborough Andrew S Sample fixation and stabilisation
EP3447141B1 (en) 2013-03-18 2020-08-05 PreAnalytiX GmbH Stabilisation of biological samples
WO2014146780A1 (en) 2013-03-18 2014-09-25 Qiagen Gmbh Stabilization and isolation of extracellular nucleic acids
FI126757B (en) * 2014-02-28 2017-05-15 Teknologian Tutkimuskeskus Vtt Oy EUTEXT SOLVENT MIXTURES AND THEIR USE
US20160374330A1 (en) * 2014-03-18 2016-12-29 Qiagen Gmbh Stabilization and isolation of extracellular nucleic acids
CN104023526B (zh) * 2014-03-24 2016-01-13 金仕生物科技（常熟）有限公司 一种处理生物材料的方法及经该方法处理的生物材料
WO2015179719A1 (en) * 2014-05-22 2015-11-26 Zoetis Services Llc Methods and apparatus for selectively processing eggs according to gender and other characteristics
CN115184120A (zh) * 2014-05-28 2022-10-14 凯杰有限公司 用于含细胞液体样品的固定剂组合物
KR20170098821A (ko) 2014-12-17 2017-08-30 에프. 호프만-라 로슈 아게 소르타아제를 사용한 １ 단계로의 이중 폴리펩티드 컨쥬게이션을 위한 효소 원-포트 반응
JP6800154B2 (ja) 2014-12-17 2020-12-16 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 結合形成酵素の活性アッセイ
US10111842B2 (en) * 2014-12-31 2018-10-30 University Of Oslo Eutectic solvents and uses thereof
WO2016144891A1 (en) 2015-03-06 2016-09-15 Bio-Rad Laboratories, Inc. Stabilized rna solutions
CN104887723A (zh) * 2015-06-18 2015-09-09 天津理工大学 一种利用低共熔溶剂提取银杏叶中黄酮类化合物的方法
EP3329011B1 (en) * 2015-07-30 2019-12-18 Arcis Biotechnology Holdings Limited Method and composition
GB201513492D0 (en) 2015-07-30 2015-09-16 Arcis Biotechnology Holdings Ltd Method and composition
WO2017027439A1 (en) * 2015-08-07 2017-02-16 Yangchuan Xing Synthesis of deep eutectic solvent chemical precursors and their use in the production of metal oxides
CN105158129B (zh) * 2015-08-26 2018-04-17 武汉东方华康科技有限公司 一种红细胞沉降率标准品及其制备方法
EP3353310B1 (en) 2015-09-25 2020-04-29 H. Hoffnabb-La Roche Ag Process for producing thioesters employing a sortase a
WO2017050872A1 (en) 2015-09-25 2017-03-30 F. Hoffmann-La Roche Ag Transamidation employing sortase a in deep eutectic solvents
EP3353291B1 (en) 2015-09-25 2021-06-09 F. Hoffmann-La Roche AG Novel soluble sortase a
JP2017082063A (ja) * 2015-10-26 2017-05-18 日本化薬株式会社 深共晶溶媒を含む光波長変換要素およびその光波長変換要素を含む物品
CA3005694A1 (en) 2015-11-20 2017-05-26 Qiagen Gmbh Method of preparing sterilized compositions for stabilization of extracellular nucleic acids
US20170226555A1 (en) * 2016-02-05 2017-08-10 Hoffmann-La Roche Inc. Thiol-based deep eutectic solvent
WO2017155869A1 (en) * 2016-03-07 2017-09-14 X-Zell Inc. Compositions and methods for identifying rare cells
WO2017164627A2 (ko) * 2016-03-21 2017-09-28 주식회사 엘지생활건강 바이오필름 억제 또는 제거용 조성물
KR101978828B1 (ko) * 2016-03-21 2019-05-15 주식회사 엘지생활건강 바이오필름 제거용 조성물
WO2018009765A1 (en) * 2016-07-08 2018-01-11 President And Fellows Of Harvard College Determination of rna in blood or other fluids
FR3058905B1 (fr) * 2016-11-18 2020-02-28 Universite Du Littoral Cote D'opale Procede d'epuration d'un effluent gazeux
EP3571314B1 (en) * 2017-01-22 2023-12-20 Chryos, LLC Composition and method of use of the same for preserving cells for analysis
CN110520045A (zh) * 2017-02-03 2019-11-29 斯特里克公司 带防腐剂的采样管
DE102017003171A1 (de) * 2017-03-31 2018-10-04 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Tieftemperatur-indikatormischung, vorrichtung und verfahren zur überwachung eines temperaturübergangs bei tiefen temperaturen
US20220125042A1 (en) * 2017-05-17 2022-04-28 Universidade Nova De Lisboa Cryoprotectant and/or cryopreservant composition, methods and uses thereof
CN107177024B (zh) * 2017-05-23 2019-07-30 广州纽楷美新材料科技有限公司 可聚合低共熔溶剂在制备透明导电弹性体中的应用
WO2019089898A1 (en) 2017-11-02 2019-05-09 Danisco Us Inc Freezing point depressed solid matrix compositions for melt granulation of enzymes
EP3485874A1 (en) * 2017-11-17 2019-05-22 SeraNovo B.V. Method of preparing a natural deep eutectic solvent (nades)-active ingredient system; a nades-, and preferably a polymeric precipitation inhibitor containing nades-, based drug formulation technology and development method
CN107870190B (zh) * 2017-11-21 2020-02-07 中国人民解放军军事科学院军事医学研究院 脑缺血近交系长爪沙鼠的遗传生化位点标记及其应用
CN109837272B (zh) * 2017-11-27 2021-07-16 北京自然博物馆 血液组织rna成分保存剂及其制备方法
AU2018374628A1 (en) * 2017-12-01 2020-07-02 Copan Italia S.P.A. Support for the preservation of biological samples and correlated method of production
AR113996A1 (es) 2017-12-22 2020-07-08 Intervet Int Bv Vacunas líquidas de virus envueltos vivos
EP3732461A1 (en) * 2017-12-29 2020-11-04 F. Hoffmann-La Roche AG Tissue sample preparation system
CN107982299A (zh) * 2018-01-01 2018-05-04 广东汇群中药饮片股份有限公司 一种低共熔试剂保护的麸炒白术炮制方法
CN108251414A (zh) * 2018-01-17 2018-07-06 云健康基因科技（上海）有限公司 骨髓细胞基因组dna的提取方法及提取试剂盒
CN108375571B (zh) * 2018-02-05 2019-11-26 苏州长光华医生物医学工程有限公司 一种用于化学发光免疫检测的磁颗粒试剂及试剂盒
JP7178607B2 (ja) * 2018-02-23 2022-11-28 学校法人麻布獣医学園 アミロイドタンパク質を抽出する試薬
CN108094412A (zh) * 2018-03-01 2018-06-01 安徽工业大学 一种用于细胞冷冻保存的新型冷冻保护剂及其应用
CN116929574A (zh) * 2018-03-14 2023-10-24 泰坦公司 使用深共晶物的温度升降指示器
CN108186575B (zh) * 2018-03-14 2020-05-22 安徽工业大学 一种基于低共熔溶剂为溶剂的包埋体系
BR112020021134A2 (pt) * 2018-04-16 2021-03-23 Merck Patent Gmbh aditivos para formulações de proteínas para aprimorar estabilidade térmica
EP3781182A4 (en) 2018-04-18 2021-11-17 Summa Health COMPOSITIONS AND METHODS OF TREATMENT OF ISCHEMIA AND CARDIOMYOPATHIA
CN110604126A (zh) * 2018-06-14 2019-12-24 宁波化奇工程技术有限公司 一种非甲醛环保病理组织固定剂
CN110633719B (zh) * 2018-06-21 2022-05-20 清华大学 一种微液滴数据的分类方法
EP3827241B1 (en) * 2018-07-24 2024-03-13 Andrew Simon Goldsborough Dissociation of biological samples
KR102220167B1 (ko) * 2018-09-04 2021-02-25 성균관대학교산학협력단 단백질 상온 안정화 및 저장용 천연공융용매
EP3851184A4 (en) * 2018-09-14 2022-06-08 Sumitomo Chemical Company Limited PROCESS FOR MAKING A MEMBRANE FOR ACID GAS SEPARATION
CN109757466B (zh) * 2018-10-29 2022-05-24 中国医学科学院阜外医院 一种尿液保存液
CN109781977B (zh) * 2019-01-09 2022-03-29 首都医科大学附属北京安定医院 IL15Rα以及相关膜蛋白检测试剂盒及其应用
CN109706113B (zh) * 2019-02-28 2022-08-26 华侨大学 一种利用低共熔溶剂提取大豆线粒体的方法
BR112021018854A2 (pt) 2019-03-29 2021-11-30 Intervet Int Bv Estabilização de bactérias mollicutes vivas em uma composição líquida
JP7615052B2 (ja) 2019-04-25 2025-01-16 アジレント・テクノロジーズ・インク ハイブリダイゼーション組成物ならびに組成物を調製および使用するための方法
CN110286019B (zh) * 2019-04-26 2021-10-15 青岛农业大学 一种去膜端黄卵的整胚固定方法
CN110441531B (zh) * 2019-08-17 2022-08-23 宁波奥丞生物科技有限公司 一种检测血液中降钙素原的试剂盒及制备方法
CN110448996A (zh) * 2019-08-21 2019-11-15 浙江工业大学 一种基于Emim[Cl]低共熔溶剂捕集二氧化硫的方法
CN111302499B (zh) * 2019-11-07 2022-04-08 桂林理工大学 一种快速催化降解己烯雌酚的方法
CN110836803A (zh) * 2019-11-15 2020-02-25 安徽雷根生物技术有限公司 一种无甲醛固定液
CN110954380B (zh) * 2019-11-18 2024-09-20 宁波瑞源生物科技有限公司 一种生化校准品用基质以及一种生化校准品
IT201900024448A1 (it) * 2019-12-18 2021-06-18 Addax Biosciences S R L Conservazione di sequenze di acidi nucleici mediante fissazione dei tessuti in formalina tamponata preparata utilizzando formaldeide deprivata di acidi
FR3107282B1 (fr) * 2020-02-14 2025-01-03 Enalees Trousses et procédés pour l’extraction d’acides nucléiques à partir d’échantillons complexes
CN110982876B (zh) * 2020-03-04 2020-05-26 圣湘生物科技股份有限公司 病毒核酸检测的预处理方法、预处理液、试剂盒及其用途
CN111088319B (zh) * 2020-03-25 2020-07-21 深圳市上为生物科技有限公司 一种灭活型病毒样本rna保存液及其制备方法
WO2021205042A1 (en) 2020-04-10 2021-10-14 RNAssist Limited Composition and method for inactivating a virus
CN111218502B (zh) * 2020-04-23 2020-07-21 圣湘生物科技股份有限公司 提升qPCR检测性能的组合物、反应液、用途及方法
CN111397997A (zh) * 2020-04-26 2020-07-10 中烨(山东)检验检测有限公司 一种用于新鲜组织样本固定的组织固定液
CN111397998A (zh) * 2020-04-26 2020-07-10 中烨(山东)检验检测有限公司 一种用于组织细胞切片的染色液
GB202007246D0 (en) * 2020-05-15 2020-07-01 Map Ip Holding Ltd Sample preparation and analysis methods
JP2023533323A (ja) * 2020-07-10 2023-08-02 アキュタス ダイアグノスティクス，インク． 血液及び体液からの微生物の単離及び迅速検出のための方法及び組成物
CN111982626B (zh) * 2020-08-20 2023-07-25 江苏瑞思坦生物科技有限公司 一种软骨球快速石蜡切片鉴定方法
WO2022103843A1 (en) * 2020-11-11 2022-05-19 George Mason Research Foundation, Inc. Laser capture microdissection visualization chemistry
WO2022101877A1 (pt) * 2020-11-13 2022-05-19 Targetalent, Lda Composição de criopreservação de amostras biológicas para pcr
KR20230105332A (ko) * 2020-11-13 2023-07-11 유니베르시다데 도 미노 공융 조성물, 방법 및 이의 용도
CN112400861B (zh) * 2020-11-24 2022-02-22 河南赛诺特生物技术有限公司 一种用于快速细胞免疫组化的细胞保存液及其制备方法和应用
CN112662561A (zh) * 2021-01-15 2021-04-16 中农新科(苏州)有机循环研究院有限公司 一种常温细菌核糖核酸保护剂及其制备方法与应用
CN113218723A (zh) * 2021-03-16 2021-08-06 吴敏 一种用于显微镜观察的组合物及其制备方法和应用
CN112760360B (zh) * 2021-03-22 2023-12-19 洛阳赛奥生物工程技术有限公司 一种rna保护剂及其应用
WO2022201519A1 (ja) 2021-03-26 2022-09-29 株式会社ダイセル 共融混合物及び液状組成物
CN113125482A (zh) * 2021-04-20 2021-07-16 浙江科技学院 一种用于冷冻电镜制样的低共熔溶剂及其制备方法
CN113009184A (zh) * 2021-04-20 2021-06-22 浙江科技学院 一种基于低共熔溶剂制备冷冻电镜检测样品的方法
WO2022254209A1 (en) * 2021-06-04 2022-12-08 Imperial College Innovations Limited Stable composition
CN113533292B (zh) * 2021-08-24 2024-04-26 常州工学院 一种双酚s含量的荧光检测方法
CN113484192B (zh) * 2021-09-06 2021-12-14 广汉市福客科技有限公司 一种下沉式延缓起泡剂的评价装置与评价方法
CN113817718B (zh) * 2021-09-16 2023-10-24 上海市刑事科学技术研究院 一种利用低共熔溶剂裂解细胞并直接用于聚合酶链式扩增反应的方法
CN113740134B (zh) * 2021-09-24 2023-11-28 中国电建集团成都勘测设计研究院有限公司 一种用于三轴试验土样制备装置
US11753677B2 (en) 2021-11-10 2023-09-12 Encodia, Inc. Methods for barcoding macromolecules in individual cells
CN114082218B (zh) * 2021-12-03 2022-12-27 齐鲁工业大学 一种可调控且选择性提取木质素的开关型低共熔溶剂的制备与应用
CN114740121A (zh) * 2022-04-24 2022-07-12 杭州广科安德生物科技有限公司 基于一级质谱分析的双氨基酸稳定同位素标记方法及应用
CN115011671A (zh) * 2022-07-26 2022-09-06 郑州标源生物科技有限公司 呼吸道核酸复合质控品的制备方法
KR102835401B1 (ko) * 2022-09-19 2025-07-16 연세대학교 산학협력단 하이드로겔 조직의 팽윤을 억제하는 조직투명화 혼합물
WO2024075941A1 (ko) * 2022-10-04 2024-04-11 인천대학교 산학협력단 세포밖 소포체 또는 세포의 고흡수성 수지 기반 표면 고정 기술
CN115678191B (zh) * 2022-11-08 2023-09-26 曲阜师范大学 一种高机械强度抗冻自粘自修复导电弹性体的制备方法及应用
CN115777695B (zh) * 2023-02-07 2023-05-12 成都海默云因医学检验实验室有限公司 适用于脑脊液细胞形态学检查的复合保存液及其制备方法
EP4414458A1 (de) * 2023-02-07 2024-08-14 Senckenberg Gesellschaft Für Naturforschung Collect & extract - lösung für die sammlung und lagerung biologischer probentypen zur extraktion von biomolekülen
CN118518439B (zh) * 2023-02-17 2025-09-16 清华大学 离子液体制剂和组织处理方法及其应用
CN115993457B (zh) * 2023-03-22 2023-06-09 广州科方生物技术股份有限公司 一种用于化学发光免疫分析仪检测光子含量的发光剂及其制配方法
CN116891910A (zh) * 2023-04-23 2023-10-17 北京森康生物技术开发有限公司 一种具有抗干扰能力的非洲猪瘟病毒荧光pcr检测试剂盒
CN116891945B (zh) * 2023-07-19 2025-08-08 昆明理工大学 一种从废旧ncm型锂离子电池正极中浸出锂镍钴锰的方法
CN116656671B (zh) * 2023-07-27 2023-11-21 南京诺唯赞生物科技股份有限公司 一种rna提取方法
CN117054182B (zh) * 2023-07-31 2024-03-15 广东湛江海洋医药研究院 一种可塑形的组织透明化试剂及其制备方法和使用方法
CN117129605B (zh) * 2023-10-25 2024-02-02 济南和合医学检验有限公司 一种液相色谱串联质谱法检测11种抗高血压药物和3种代谢物的方法
CN117949646B (zh) * 2023-12-31 2025-03-07 深圳市新产业生物医学工程股份有限公司 试剂组合以及免离心的全血中目标免疫抑制剂的检测方法
CN118374486B (zh) * 2024-05-24 2025-02-11 信天翁生物科技(广州)有限公司 一种基于柱式法的rna提取方法
CN120310965A (zh) * 2025-06-19 2025-07-15 山东亦度生物技术有限公司 一种轮状病毒检测的引物对、试剂盒、应用及减毒活疫苗病毒滴度的检测方法
CN120400022B (zh) * 2025-07-03 2025-09-12 江苏同萃科创服务有限公司 一种人参愈伤组织来源外泌体的高效提取方法、外泌体及其应用

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3667928A (en) * 1969-11-12 1972-06-06 Union Oil Co Increased component concentration of nutrient solutions of trace metals
US4579580A (en) * 1982-12-22 1986-04-01 Moore William P Urea-methylolurea plant food composition
US5010183A (en) 1989-07-07 1991-04-23 Macfarlane Donald E Process for purifying DNA and RNA using cationic detergents
US5300635A (en) 1993-02-01 1994-04-05 University Of Iowa Research Foundation Quaternary amine surfactants and methods of using same in isolation of nucleic acids
US6777210B1 (en) 1998-09-24 2004-08-17 Ambion, Inc. Method and reagents for inactivating ribonucleases RNase A, RNase I and RNase T1
DE10031236A1 (de) 2000-06-27 2002-01-10 Qiagen Gmbh Verwendung von Carbonsäuren und anderen Additiven in Kombination mit kationischen Verbindungen zur Stabilisierung von Nukleinsäuren in biologischen Materialien
IN188857B (enExample) * 2000-07-14 2002-11-16 Govind Kane Dr Shantaram
GB0023706D0 (en) * 2000-09-27 2000-11-08 Scionix Ltd Ionic liquids
CA2428864C (en) * 2000-11-08 2011-04-12 Becton, Dickinson And Company Method and device for collecting and stabilizing a biological sample
US6602718B1 (en) * 2000-11-08 2003-08-05 Becton, Dickinson And Company Method and device for collecting and stabilizing a biological sample
US20040077519A1 (en) 2002-06-28 2004-04-22 The Procter & Gamble Co. Ionic liquid based products and method of using the same
GB0217963D0 (en) * 2002-08-02 2002-09-11 Cyclops Genome Sciences Ltd Purification of nucleic acids
US20060094616A1 (en) 2004-11-01 2006-05-04 Hecht Stacie E Ionic liquids derived from surfactants
US20060188892A1 (en) 2005-02-18 2006-08-24 Ambion, Inc. Enzymatic digestion of tissue
US7763715B2 (en) 2005-04-22 2010-07-27 The Procter & Gamble Company Extracting biopolymers from a biomass using ionic liquids
CA2629586C (en) * 2007-04-20 2016-05-24 F.Hoffmann-La Roche Ag Adsorption of nucleic acids to solid phases under low-salt conditions
CA2629589C (en) * 2007-04-20 2016-03-29 F.Hoffmann-La Roche Ag Isolation and purification of nucleic acid molecules with a solid phase
DE102007025277A1 (de) 2007-05-31 2008-12-04 Qiagen Gmbh Verfahren zur Stabilisierung einer biologischen Probe
US8247198B2 (en) 2007-09-21 2012-08-21 Friedrich Srienc Enzymatic processing in deep eutectic solvents
WO2009085574A2 (en) * 2007-12-28 2009-07-09 Spring Bioscience Corporation Microwave antigen retrieval in non-aqueous solvents
US8022014B2 (en) 2008-03-26 2011-09-20 Shrieve Chemical Products, Inc. Deep eutectic solvents and applications
US20120141980A1 (en) * 2009-08-17 2012-06-07 Merk Patent Gesellschaft Mit Beschrankter Haftung Method for isolating viruses
EP2471497A4 (en) * 2009-08-26 2013-10-09 Otsuka Medical Devices Co Ltd MEDICAL DEVICE FOR PLACEMENT IN A LUMEN AND METHOD FOR THE PRODUCTION THEREOF
MX341433B (es) 2009-12-23 2016-08-18 Colgate-Palmolive Company * Composicion antitranspirante/desodorante anhidra liquida.
NL2004835C2 (en) 2010-06-07 2011-12-08 Univ Leiden Process for extracting materials from biological material.
US8292625B2 (en) 2010-07-23 2012-10-23 Pulpdent Corporation Radically curable urethane dimethacrylates and compositions thereof for tougher dental prosthetics
WO2012145522A2 (en) 2011-04-19 2012-10-26 Georgia Tech Research Corporation Deep eutectic solvent systems and methods
WO2014055936A1 (en) 2012-10-04 2014-04-10 Integenx Inc. Preservation of biological materials in non-aqueous fluid media
GB201303666D0 (en) 2013-03-01 2013-04-17 Goldsborough Andrew S Sample fixation and stabilisation
US9840731B2 (en) 2013-03-14 2017-12-12 Gentegra, Llc Preservation of biological materials in non-aqueous fluid media

Also Published As

Publication number Publication date
CA2904765C (en) 2023-01-03
EP3788873A1 (en) 2021-03-10
US20200225128A1 (en) 2020-07-16
US20240027309A1 (en) 2024-01-25
US20180058988A1 (en) 2018-03-01
EP3430903B1 (en) 2020-10-21
AU2014222618B2 (en) 2017-12-14
ES2709064T3 (es) 2019-04-15
CN105392363B (zh) 2017-09-29
US10393633B2 (en) 2019-08-27
US20170328819A1 (en) 2017-11-16
EP2961268B1 (en) 2018-11-21
CN105392363A (zh) 2016-03-09
JP2019141098A (ja) 2019-08-29
AU2014222618A1 (en) 2015-10-29
EP2961268A1 (en) 2016-01-06
EP3430903A1 (en) 2019-01-23
GB201303666D0 (en) 2013-04-17
JP6527616B2 (ja) 2019-06-05
US20140295404A1 (en) 2014-10-02
JP2018113982A (ja) 2018-07-26
US9696247B2 (en) 2017-07-04
WO2014131906A1 (en) 2014-09-04
JP2016510976A (ja) 2016-04-14
US10539488B2 (en) 2020-01-21
CA2904765A1 (en) 2014-09-04

Similar Documents

Publication Publication Date Title
JP6317372B2 (ja) 試料固定及び安定化
EP3827241B1 (en) Dissociation of biological samples
US20110027862A1 (en) Sample stabilization
US8372637B2 (en) Method for stabilising a biological sample
EP2598660B1 (en) Compositions for stabilizing dna, rna and proteins in blood and other biological samples during shipping and storage at ambient temperatures
US8193001B2 (en) Compositions and methods for preserving RNA in biological samples
JP2005501523A (ja) 界面活性剤およびプロテアーゼを使用して核酸を単離するための組成物、方法およびキット
KR20070115874A (ko) Ｄｎａ 분석용 생물 시료를 보관 및 처리하는 시약 및 방법
KR101777168B1 (ko) 별도의 세포 용해 과정 없이 핵산을 추출하기 위한 검체 수송 배지 조성물 및 이의 용도
EP4133062A1 (en) Composition and method for inactivating a virus
KR102786563B1 (ko) 수송배지로서 혈액 내의 핵산 보존용 조성물 및 이를 이용한 핵산의 보존방법
KR20250020999A (ko) 혈액 시료 내 성분 고정을 위한 조성물

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20170228

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20170228

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20180227

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20180329

R150 Certificate of patent or registration of utility model

Ref document number: 6317372

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250