CN105158129B - 一种红细胞沉降率标准品及其制备方法 - Google Patents
一种红细胞沉降率标准品及其制备方法 Download PDFInfo
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- CN105158129B CN105158129B CN201510530401.2A CN201510530401A CN105158129B CN 105158129 B CN105158129 B CN 105158129B CN 201510530401 A CN201510530401 A CN 201510530401A CN 105158129 B CN105158129 B CN 105158129B
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- liquid
- erythrocyte
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- 210000003743 erythrocyte Anatomy 0.000 title claims abstract description 49
- 238000004062 sedimentation Methods 0.000 title claims abstract description 32
- 238000002360 preparation method Methods 0.000 title abstract description 7
- 239000007788 liquid Substances 0.000 claims abstract description 40
- 210000004369 blood Anatomy 0.000 claims abstract description 22
- 239000008280 blood Substances 0.000 claims abstract description 22
- 239000000203 mixture Substances 0.000 claims abstract description 15
- 238000005119 centrifugation Methods 0.000 claims abstract description 12
- 239000003223 protective agent Substances 0.000 claims abstract description 12
- 210000004027 cell Anatomy 0.000 claims abstract description 11
- 239000003755 preservative agent Substances 0.000 claims abstract description 10
- 239000006228 supernatant Substances 0.000 claims abstract description 10
- 239000002245 particle Substances 0.000 claims abstract description 8
- 238000007689 inspection Methods 0.000 claims abstract description 7
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims abstract description 6
- 239000001509 sodium citrate Substances 0.000 claims abstract description 6
- 241001465754 Metazoa Species 0.000 claims abstract description 5
- 238000007710 freezing Methods 0.000 claims abstract description 5
- 238000007789 sealing Methods 0.000 claims abstract description 5
- 238000012797 qualification Methods 0.000 claims abstract description 4
- 210000000601 blood cell Anatomy 0.000 claims abstract description 3
- 230000001413 cellular effect Effects 0.000 claims abstract description 3
- 238000003860 storage Methods 0.000 claims abstract description 3
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 claims description 8
- 239000004327 boric acid Substances 0.000 claims description 8
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 4
- SXRSQZLOMIGNAQ-UHFFFAOYSA-N Glutaraldehyde Chemical compound O=CCCCC=O SXRSQZLOMIGNAQ-UHFFFAOYSA-N 0.000 claims description 4
- WJEIYVAPNMUNIU-UHFFFAOYSA-N [Na].OC(O)=O Chemical compound [Na].OC(O)=O WJEIYVAPNMUNIU-UHFFFAOYSA-N 0.000 claims description 4
- 244000309466 calf Species 0.000 claims description 4
- BNIILDVGGAEEIG-UHFFFAOYSA-L disodium hydrogen phosphate Chemical compound [Na+].[Na+].OP([O-])([O-])=O BNIILDVGGAEEIG-UHFFFAOYSA-L 0.000 claims description 4
- 238000003682 fluorination reaction Methods 0.000 claims description 4
- 210000002966 serum Anatomy 0.000 claims description 4
- 239000008103 glucose Substances 0.000 claims description 3
- ULWHHBHJGPPBCO-UHFFFAOYSA-N propane-1,1-diol Chemical class CCC(O)O ULWHHBHJGPPBCO-UHFFFAOYSA-N 0.000 claims description 3
- 238000000034 method Methods 0.000 claims description 2
- KDCGOANMDULRCW-UHFFFAOYSA-N 7H-purine Chemical compound N1=CNC2=NC=NC2=C1 KDCGOANMDULRCW-UHFFFAOYSA-N 0.000 claims 2
- 210000004907 gland Anatomy 0.000 claims 1
- 238000002347 injection Methods 0.000 abstract description 5
- 239000007924 injection Substances 0.000 abstract description 5
- 229930024421 Adenine Natural products 0.000 description 3
- GFFGJBXGBJISGV-UHFFFAOYSA-N Adenine Chemical compound NC1=NC=NC2=C1N=CN2 GFFGJBXGBJISGV-UHFFFAOYSA-N 0.000 description 3
- 229960000643 adenine Drugs 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 2
- 239000008202 granule composition Substances 0.000 description 2
- 244000144977 poultry Species 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000003204 osmotic effect Effects 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 238000003908 quality control method Methods 0.000 description 1
- 238000004445 quantitative analysis Methods 0.000 description 1
Landscapes
- Investigating Or Analysing Biological Materials (AREA)
Abstract
Description
红细胞颗粒混合物 | 枸橼酸钠 |
0.2ml | 1.8ml |
0.4ml | 1.6ml |
0.6ml | 1.4ml |
0.8ml | 1.2ml |
1.0ml | 1.0ml |
红细胞颗粒混合物 | 枸橼酸钠 |
0.2ml | 1.8ml |
0.4ml | 1.6ml |
0.6ml | 1.4ml |
0.8ml | 1.2ml |
1.0ml | 1.0ml |
Claims (2)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201510530401.2A CN105158129B (zh) | 2015-08-26 | 2015-08-26 | 一种红细胞沉降率标准品及其制备方法 |
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CN201510530401.2A CN105158129B (zh) | 2015-08-26 | 2015-08-26 | 一种红细胞沉降率标准品及其制备方法 |
Publications (2)
Publication Number | Publication Date |
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CN105158129A CN105158129A (zh) | 2015-12-16 |
CN105158129B true CN105158129B (zh) | 2018-04-17 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CN201510530401.2A Active CN105158129B (zh) | 2015-08-26 | 2015-08-26 | 一种红细胞沉降率标准品及其制备方法 |
Country Status (1)
Country | Link |
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CN (1) | CN105158129B (zh) |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0236949A2 (en) * | 1986-03-07 | 1987-09-16 | Takeda Chemical Industries, Ltd. | Blood preservation |
CN1310797A (zh) * | 1998-06-30 | 2001-08-29 | 莱密纳股份有限公司 | 细胞学和组织学固定剂组合物及其使用方法 |
CN1683522A (zh) * | 2005-03-04 | 2005-10-19 | 江西特康科技有限公司 | 全血质控物细胞生物活性保护剂及其制法 |
CN103267715A (zh) * | 2013-05-16 | 2013-08-28 | 李滨 | 红细胞沉降速率的自动检测方法及装置 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB201303666D0 (en) * | 2013-03-01 | 2013-04-17 | Goldsborough Andrew S | Sample fixation and stabilisation |
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2015
- 2015-08-26 CN CN201510530401.2A patent/CN105158129B/zh active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0236949A2 (en) * | 1986-03-07 | 1987-09-16 | Takeda Chemical Industries, Ltd. | Blood preservation |
CN1310797A (zh) * | 1998-06-30 | 2001-08-29 | 莱密纳股份有限公司 | 细胞学和组织学固定剂组合物及其使用方法 |
CN1683522A (zh) * | 2005-03-04 | 2005-10-19 | 江西特康科技有限公司 | 全血质控物细胞生物活性保护剂及其制法 |
CN103267715A (zh) * | 2013-05-16 | 2013-08-28 | 李滨 | 红细胞沉降速率的自动检测方法及装置 |
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Publication number | Publication date |
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CN105158129A (zh) | 2015-12-16 |
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Inventor after: Ding Huanhong Inventor after: Wang Su Inventor after: Zhu Qing Inventor after: Wang Wendong Inventor before: Wang Su Inventor before: Duan Yanli Inventor before: Liu Yong |
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Effective date of registration: 20231114 Address after: 519000 room 1301, building 3, scientific research incubation building, phase II, Tsinghua Science Park, 101 University Road, Tangjiawan Town, high tech Zone, Zhuhai, Guangdong Patentee after: Zhuhai Langtai Biotechnology Co.,Ltd. Address before: 430000 floors 1-2, plant 2, economic development zone, Hannan District, Wuhan City, Hubei Province (Wuhan Gaoyuan Biotechnology Development Co., Ltd.) Patentee before: WUHAN DONGFANG HUAKANG TECHNOLOGY Co.,Ltd. |
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